Clinical trials: Idiopathic Infertility
Male Infertility Due to Hypospermatogenesis
Omega-3 PUFA for Treatment of Patients With Idiopathic Oligoasthenoteratospermia
Investigators have previously found that sperm quality was not related to obesity indicators, such as body mass index (bmi), waist circumference, waist-hip ratio, girth ratio and serum lipid, but seminal plasma lipids could…
- Trial name
- NCT03634644
- Testing
- Omega 3 fatty acid
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jinling Hospital, China
Oligoasthenoteratozoospermia, Male Infertility
Comparative Efficacy of Antioxidants Alone Versus Combined Therapy With SERMs or FSH in Normogonadotropic Idiopathic OAT Patients: A Randomized Controlled Trial
This prospective randomized controlled trial will compare three treatment approaches for men with idiopathic oligoasthenoteratozoospermia (OAT), a condition characterized by abnormalities in sperm count, movement, and shape…
- Trial name
- NCT07862725
- Testing
- Antioxidants + Clomiphene Citrate, Antioxidants + FSH, Antioxidants Alone
- Where
- Qatar
- Volunteers
- 360 people
- Sponsor
- Hamad Medical Corporation
Infertility Unexplained
Modulation of Reproductive Microbiota by Ligilactobacillus Salivarius CECT5713
The objective of the project is to elucidate if the oral administration of Ligilactobacillus salivarius CECT5713 is capable of improving the rates of term pregnancies in couples with infertility problems of unknown cause.
- Trial name
- NCT06290518
- Testing
- Ligilactobacillus salivarius CECT5713
- Where
- 3 sites in Spain
- Volunteers
- 72 people
- Sponsor
- Biosearch S.A.
Idiopathic Infertility
Effect of Pentoxifylline and Zinc Co-administration in Patients With Oligoasthenoteratozoospermia
The aim of this study is to investigate the impact of co-administration of Pentoxifylline and Zinc sulfate on oxidative stress, apoptosis, and inflammation, sperm capacitation and parameters in infertile men.
- Trial name
- OAT (NCT05156684)
- Testing
- Pentoxifylline, zinc, zinc + pentoxifylline
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Arak University of Medical Sciences
Oligoasthenoteratozoospermia, Male Infertility
Efficacy Comparison of Tamoxifen and Tamoxifen With Antioxidants on Semen Quality of Male With Idiopathic Infertility
Objective of the study is to compare the efficacy of tamoxifen alone \& tamoxifen with antioxidant on semen quality of infertile male with abnormal parameters (sperm count, motility, vitality, morphology) .Infertility is defines…
- Trial name
- NCT05200663
- Testing
- Tab Tamoxifen 10 mg, Tab Tamoxifen 10mg,Cap vitamin E 400mg
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Sharif Medical Research Center
Male Idiopathic Infertility
A Trial to Compare Efficacy and Safety of Follitropin Delta Versus Placebo (Inactive Treatment) in the Treatment of Men With Idiopathic Infertility (Unexplained Reduction of Semen Quality) (ADAM)
The primary purpose of this trial is to investigate whether men with idiopathic infertility (unexplained reduction of semen quality), after being treated with a daily dose of 12 µg recombinant follicle stimulating hormone (rFSH)…
- Trial name
- NCT05403476
- Testing
- FE 999049
- Where
- 22 sites in United States, Belgium and 5 more
- Volunteers
- 4 people
- Sponsor
- Ferring Pharmaceuticals
Infertility, Infertility Unexplained
PMA-FERTITHEQUE Biocollection
Creation of a patient library in Medically Assisted Procreation to allow the implementation of further research with the following objectives: To identify new relevant biomarkers in patients who will carry a pregnancy to term To…
- Trial name
- FERTITHEQUE (NCT05599724)
- Testing
- Biocollection
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Brest
Men Infertility
The Therapeutic Effect of Co-administration of Pentoxifylline and Zinc in Men With Idiopathic Asthenozoospermia
The aim of this study was to investigate the therapeutic effect of co-administration of pentoxifylline and zinc on sperm apoptosis in men with idiopathic infertility
- Trial name
- PTX-Zn (NCT05178953)
- Testing
- Zinc Sulfate 220 mg Capsules, Pentoxifylline
- Where
- 2 sites in Iran
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Arak University of Medical Sciences
Male Infertility
Myo-inositol and an Antioxidant Mix for the Treatment of Vietnamese Infertile Men
The aim of this study is to evaluate if Myo-inositol, N-Acetyl-Cysteine plus a cocktail of antioxidants could be able to increase spermatozoa parameters and reduce semen hyper-viscosity
- Trial name
- NCT03726450
- Testing
- Andrositol Plus
- Where
- Vietnam
- Volunteers
- 55 people
- Sponsor
- Andrology and Fertility Hospital of Hanoi
Infertility, Male
Role of Nutritional Support in Idiopathic Male Infertility
Approximately 100 males with idiopathic infertility and oligo- and/or astheno- and/or and/or teratozoospermia and fertile woman will take a Test dietary supplement (TDS), containing carnitine, vitamins and trace elements (active…
- Trial name
- NCT03588949
- Testing
- Dietary Supplement with L-carnitine (FertilHom), Control Dietary Supplement
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- NATURAmedicatrix Sàrl
Male Infertility
Impact of Coenzyme Q10 and Selenium on Seminal Fluid and Semen Antioxidant Status
The study was conducted to assess the impact of coenzyme Q10 and selenium on seminal fluid parameters and antioxidant status in infertile men.
- Trial name
- NCT03834831
- Testing
- Coenzyme Q10, Selenium
- Where
- Iraq
- Volunteers
- 70 people
- Sponsor
- University of Sumer
Infertility Unexplained, Oligospermia
Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia
Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia
- Trial name
- infertility (NCT06342856)
- Testing
- co enzyme Q10 , L- Carnitine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Osteoarthritis, Hip, Coxarthrosis; Primary
Osseointegration of THA Grafted by PolyNASS (ACTISURF-CERAFIT® ) Versus Non-grafted THA (CERAFIT®)
The infection rate after Total Hip Arthroplasty (THA) is about 1%. It is a serious condition, with high morbidity, sometimes fatal, requiring costly treatment.
- Conditions
- Osteoarthritis, Hip, Coxarthrosis; Primary, Coxarthrosis; Secondary, Osteonecrosis; Aseptic, Idiopathic
- Trial name
- NCT03113981
- Testing
- Total Hip Arthroplasty
- Where
- 7 sites in France
- Volunteers
- 340 people
- Sponsor
- Societe ACTIVBIOMAT
Oligospermia
A Clinical Study of Gulingji Capsule in the Treatment of Idiopathic Oligospermia, Asthenia, and Teratozoospermia
The object of study for patients with idiopathic disease of OAT, the use of multicenter, randomized, double-blind, controlled, prospective clinical research, choose according to row, standard units of idiopathic male infertility…
- Trial name
- NCT05320536
- Testing
- Guilingji Capsule
- Where
- 4 sites in China
- Volunteers
- 240 people
- Sponsor
- Jinling Hospital, China
Idiopathic Infertility
Nasal Oxcytocin During IUI
Placebo-controlled study. Application of nasal oxytocin (8 IU) during intrauterine insemination in 86 patients.
- Trial name
- Oxy (NCT00805662)
- Where
- Germany
- Volunteers
- 86 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Male Infertility
FSH Receptor Polymorphism p.N680S and Efficacy of FSH Therapy
CONDITION: Idiopathic male infertility In men with idiopathic infertility, the sperm DNA fragmentation index (DFI) within 12 weeks of FSH therapy and 12 weeks follow-up improves depending on the FSHR genotype as assessed by the…
- Trial name
- NCT02349945
- Testing
- follitropin alpha
- Where
- 6 sites in Germany, Italy
- Volunteers
- 88 people
- Sponsor
- Azienda USL Modena
APHRODITE Group
Gonadotropin Therapy in Idiopathic Hypogonadal Non-Obstructive
The goal of this clinical trial is to determine whether short-term gonadotropin therapy (hCG + FSH) can increase sperm availability for ICSI in men with idiopathic non-obstructive azoospermia (NOA) and hypogonadism.
- Trial name
- GTIHNO (NCT07540611)
- Testing
- No intervention, hCG + FSH therapy
- Where
- 8 sites in India
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- Indira IVF Hospital Pvt Ltd
Male Infertility
Study to Verify the Efficacy of a Product Containing 125 mg of TetraSOD® for the Treatment of Male Infertility
TetraSOD® is a unique marine phytoplankton (Tetraselmis chuii) SOD-rich ingredient that is grown under patent-protected technology exclusively designed by the company Fitoplancton Marino, S.L. (Spain).
- Trial name
- NCT06324071
- Testing
- Marine microalgae Tetraselmis chuii with high Superoxide Dismutase (SOD) activity
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fitoplancton Marino, S.L.
Infertility
The Value of HBA in the Evaluation of Idiopathic Infertility
We would like to determine if HBA® testing of sperm in couples with presumed idiopathic infertility will reveal lower binding percentages than in couples with an identifiable cause of infertility either male factor or tubal factor
- Trial name
- NCT01683435
- Testing
- HBA binding assay
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center