Clinical trials: Idiopathic Parkinson Patients
Parkinson's Disease
A Study of Three Doses of TCH346 in Patients With Early Parkinson's Disease to Evaluate Safety and Efficacy
This study will investigate the effect of TCH346 compared to placebo in delaying the need for symptomatic treatment with dopaminergic agents
- Trial name
- NCT00407212
- Testing
- TCH346 (dibenz[b,f]oxepin-10-ylmethyl-prop-2-ynyl-amine, hydrogen maleate salt)
- Where
- 45 sites in United States, Brazil and 7 more
- Volunteers
- 301 people
- Sponsor
- Novartis
Adjustment Disorder
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
The purpose of this study is to determine if treatment with a single dose of RE104 for Injection reduces depressive symptoms or depressive symptoms mixed with anxiety symptoms in participants with Adjustment Disorder due to…
- Trial name
- NCT07002034
- Testing
- RE104 for Injection
- Where
- 32 sites in United States
- Volunteers
- 100 people
- Sponsor
- Reunion Neuroscience Inc
Idiopathic Parkinson's Disease
The Acute Effect of Cervical Mobilization in Parkinson's Disease
Patients with Idiopathic Parkinson's disease have balance and gait problems due to sensory and motor impairments. In the literature, there are lots of studies including various approaches for rehabilitation of these parameters…
- Trial name
- NCT04524143
- Testing
- cervical mobilization, control
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Hacettepe University
Parkinson Disease
tDCS for Dual-task Performance in Patients With PD
The purpose of this study is to investigate the optimal stimulation location of transcranial direct current stimulation to improve the dual-task performance in patients with Parkinson's disease.
- Trial name
- NCT04504422
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Idiopathic Parkinson's Disease
PET/MR Imaging in Patients With Short and Long Standing Parkinson's Disease
Parkinson's disease (PD) is a chronic, progressive, neurodegenerative disease that affects 1% of the population older than 60 years.
- Trial name
- NCT02801110
- Volunteers
- 40 people
- Sponsor
- david groshar
Parkinson Disease
Post Marketing Surveillance Study of Sifrol® in Patients With Idiopathic Parkinson's Disease
Study to document pramipexole dosing during monotherapy, occurrence of fluctuations and dyskinesias, dose increases after deterioration of Parkinson's disease (PD) symptoms, assessment of the reasons for add-on treatment with…
- Trial name
- NCT02248181
- Testing
- Pramipexole
- Volunteers
- 442 people
- Sponsor
- Boehringer Ingelheim
Parkinson Disease, Treatment Adherence
Comparison of Dopamin Level in Idiopathic Parkinson's Patients
Our primary aim is to compare the change in blood dopamine levels with a single dose of these two drugs in patients with unilateral findings or axial involvement.
- Trial name
- NCT06115538
- Testing
- Levodopa
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Idiopathic Parkinson's Disease
Impact of Deep Brain Stimulation of Subthalamic Nucleus on the Hepatic Glucose Production in Parkinson's Disease
Parkinson' disease is a neurodegenerative disorder characterised by bradykinesia, rigidity, rest tremor and postural instability.
- Trial name
- NCT00663312
- Testing
- e.g., Protein and calorie controlled diet; Self-hypnotic relaxation
- Where
- France
- Volunteers
- 8 people
- Sponsor
- University Hospital, Clermont-Ferrand
Idiopathic Parkinson's Disease
Efficacy and Safety Study of Inhaled CVT 301 in Parkinson's Disease Patients for Treatment of OFF Episodes
This randomized, multicenter, placebo-controlled, double-blind study will evaluate the efficacy and safety of inhaled CVT 301 compared with placebo in PD patients experiencing motor response fluctuations (OFF phenomena) as an…
- Trial name
- NCT01777555
- Testing
- CVT-301
- Where
- 22 sites in United States, Italy and 2 more
- Volunteers
- 89 people
- Sponsor
- Acorda Therapeutics
Parkinson's Disease
Deep Brain Stimulation (DBS) For Parkinson's Disease: Caudal Zona Incerta Versus Subthalamic Nucleus
The aim of this study is to analyze the effects of two different targets of deep brain stimulation: caudal Zona incerta and Nucleus subthalamicus.
- Trial name
- NCT00888095
- Testing
- deep brain stimulation
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Charite University, Berlin, Germany
Major Depressive Disorder, Idiopathic Parkinson Disease
Study on the Tolerability of Duloxetine in Depressed Patients With Parkinson's Disease
This study aims to assess the tolerability of duloxetine, 60mg once daily, in open label fashion, in depressed patients with Parkinson's disease during 12 weeks treatment.
- Trial name
- NCT00437125
- Testing
- Duloxetine hydrochloride
- Where
- 13 sites in Italy
- Volunteers
- 151 people
- Sponsor
- Eli Lilly and Company
IDIOPATHIC PARKINSON'S DISEASE
A Trial to Evaluate the Effects of Rotigotine Transdermal Patch on Early Morning Motor Impairment and Sleep Disorders Idiopathic Parkinson's Disease
The objective of this trial is to assess the effect of rotigotine (SPM 962) on the control of early morning motor impairment and sleep disorders in subjects with idiopathic PD.
- Trial name
- NCT00243945
- Testing
- Rotigotine
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- UCB Pharma
Parkinson's Disease (Disorder)
A Study to Evaluate the Safety and Efficacy of IPX203 in Parkinson's Disease Participants With Motor Fluctuations
To evaluate the safety and efficacy of IPX203 (carbidopa and levodopa) extended-release capsules (IPX203 ER CD-LD) in comparison to immediate release (IR) CD-LD in the treatment of CD-LD-experienced participants with Parkinson's…
- Trial name
- NCT03670953
- Testing
- IR CD-LD, IPX203 ER CD-LD
- Where
- 108 sites in United States, Czechia and 6 more
- Volunteers
- 630 people
- Sponsor
- Impax Laboratories, LLC
Parkinson's Disease,Idiopathic
Comparing the Therapeutic Efficacy and Safety of DA-9701 With Domperidone in Patients With Parkinson's Disease
This study will evaluate the therapeutic efficacy and safety of DA-9701 with domperidone in patients with Parkinson's disease
- Trial name
- NCT03022201
- Testing
- DA-9701, Domperidone
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Parkinson's Disease
Efficacy and Safety of Safinamide (50 and 100mg/Day) Versus Placebo, in Patients With Mid-late Stage Parkinson's Disease
The purpose of this study is to evaluate the efficacy and safety of two doses of safinamide (50 and 100 mg/day, p.o.), compared to placebo, as add-on therapy in patients with idiopathic Parkinson's disease with motor fluctuations…
- Trial name
- NCT01187966
- Testing
- Safinamide
- Volunteers
- 669 people
- Sponsor
- Newron Pharmaceuticals SPA
Idiopathic Parkinson´s Disease, Parkinson's Disease
A Study to Assess Safety and Efficacy of Surgical Implant of RNDP-001 in Patients With Idiopathic Parkinson's Disease
This clinical trial is designed to test the safety and tolerability of the study intervention, RNDP-001, which will be implanted into the brain of study participants during a surgical procedure.
- Trial name
- NCT07106021
- Testing
- RNDP-001, Syringe Front-Loading Device
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Kenai Therapeutics
Idiopathic Parkinson's Disease
Safety, Pharmacokinetics and Efficacy Study of CVT-301 Inpatients With Parkinson's Disease and "Off" Episodes
The purpose of this study is to determine the safety, efficacy and pharmacokinetics following administration of CVT-301 in treatment of "off" episodes in Parkinson's Disease patients.
- Trial name
- NCT01617135
- Testing
- CVT-301, Sinemet (carbidopa/levodopa)
- Where
- 7 sites in Israel, Serbia and 1 more
- Volunteers
- 25 people
- Sponsor
- Acorda Therapeutics
Parkinson's Disease
A Study Assessing Change in Sense of Smell After Rasagiline Use in Parkinson's Patients
A decrease or loss of the sense of smell is very common in patients with Parkinson's Disease even in the earliest stages of the disease.
- Trial name
- PD-SOAR (NCT01007630)
- Testing
- Rasagiline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- The Parkinson's Institute
Parkinson Disease
Post Marketing Surveillance Study in Patients With Idiopathic Parkinson's Disease
Documentation of the effect of an direct or overlapping switch from another dopamine agonist to Sifrol® on motor function, psychopathological disturbances and mood, assessment of the reasons for the switch and the reasons for…
- Trial name
- NCT02231255
- Testing
- Sifrol®
- Volunteers
- 1,216 people
- Sponsor
- Boehringer Ingelheim
Parkinson Disease, Idiopathic Parkinson Disease
FDOPA PET and Nutritional Support in Parkinson's Disease
The overall goal of this study will be to further our understanding of how N Acetyl Cysteine (NAC) can help to support dopaminergic function in patients with Parkinson's disease (PD).
- Trial name
- FdopaPD2 (NCT04459052)
- Testing
- N acetyl cysteine, [F-18] Fluorodopa Positron Emission Tomography
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University