Clinical trials: IgAN
Primary IgA Nephropathy
A Trial of HRS-5965 Tablets in Primary IgA Nephropathy
The study is being conducted to evaluate the efficacy, and safety of HRS-5965 tablets for primary IgA nephropathy. To explore the effective dosage of HRS-5965 tablets for primary IgA nephropathy.
- Trial name
- NCT06137768
- Testing
- HRS-5965
- Where
- China
- Volunteers
- 123 people
- Sponsor
- Chengdu Suncadia Medicine Co., Ltd.
IgA Nephropathy
Study of Efficacy and Safety of LNP023 in Primary IgA Nephropathy Patients
The study is designed as a multicenter, randomized, double-blind, placebo controlled study to demonstrate the superiority of iptacopan (LNP023) at a dose of 200 mg b.i.d.
- Trial name
- APPLAUSE-IgAN (NCT04578834)
- Testing
- LNP023
- Where
- 177 sites in United States, Argentina and 33 more
- Volunteers
- 518 people
- Sponsor
- Novartis Pharmaceuticals
IgA Nephropathy (IgAN)
Clinical Experience With Sparsentan in Switzerland in IgA Nephropathy
An observational study tracking the clinical course of patients with IgA nephropathy.
- Trial name
- SWIAN (NCT07555301)
- Testing
- sparsentan
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Waid City Hospital, Zurich
Kidney Disease
A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy
Immunoglobulin A nephropathy (IgAN) is a kidney condition. It happens when the body's immune system creates groups of proteins (called immune complexes) that build-up in the kidneys causing swelling (inflammation).
- Trial name
- NCT06963827
- Testing
- Mezagitamab
- Where
- 181 sites in United States, Argentina and 24 more
- Volunteers
- 347 people
- Sponsor
- Takeda
IgA Nephropathy
Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy
Treatment of prednisone plus cyclophosphamide may be superior to treatment of prednisone alone in patients with advanced-stage IgA nephropathy.
- Trial name
- TOPplus-IgAN (NCT01758120)
- Testing
- prednisone plus cyclophosphamide, Prednisone alone
- Where
- China
- Volunteers
- 135 people
- Sponsor
- Guangdong Provincial People's Hospital
Glomerulonephritis, IGA
Efficacy of Immunosuppressive Therapy for IgA Nephropathy With Stage 3 or 4 CKD
The purpose of this clinical trial is to evaluate the long-term efficacy and safety of low-dose oral corticosteroids combined with cyclophosphamide therapy and low-dose corticosteroids monotherapy, on a background of maximal RAS…
- Trial name
- NCT05510323
- Testing
- Prednisolone, Prednisolone plus Cyclophosphamide
- Where
- China
- Volunteers
- 208 people
- Sponsor
- Air Force Military Medical University, China