Clinical trials: Ileal Pouch
Ileal Pouch
Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)
The aim of this study is to assess the safety and preliminary efficacy of treatment with EXE-346, a live biotherapeutic, which may reduce bowel movement frequency in patients with an ileal pouch-anal anastomosis (IPAA) and lead…
- Trial name
- PROF (NCT05938465)
- Testing
- EXE-346
- Where
- 8 sites in United States
- Volunteers
- 50 people
- Sponsor
- Exegi Pharma, LLC
Faecal Incontinence
A Study to Evaluate Topical Phenylephrine Gel in the Management of Faecal Incontinence
The aim of the study is to test the hypothesis that topical application of phenylephrine improves faecal continence and quality of life in subjects with passive faecal incontinence after ileo-anal pouch construction.
- Trial name
- NCT00420797
- Testing
- 10% Phenylephrine hydrochloride gel
- Where
- United Kingdom
- Sponsor
- S.L.A. Pharma AG
Familial Adenomatous Polyposis (FAP)
Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
The main goal of this clinical trial is to learn if the drug eRapa works to slow down the progression of disease in patients diagnosed with Familial Adenomatous Polyposis (FAP). Researchers will compare eRapa to Placebo.
- Trial name
- SERENTA (NCT06950385)
- Testing
- eRapa (encapsulated rapamycin)
- Where
- 29 sites in United States, Denmark and 5 more
- Volunteers
- 168 people
- Sponsor
- Rapamycin Holdings Inc.