Clinical trials: Ileo-colonic Anastomoses
Familial Adenomatous Polyposis
Effect of EPA-FFA on Polypectomy in Familial Adenomatous Polyposis
2 Year randomised, double-blind, placebo-controlled, parallel group study to determine the safety and efficacy of EPA-FFA gastro resistant capsules in FAP.
- Trial name
- NCT03806426
- Testing
- Eicosapentaenoic acid free fatty acid (EPA-FFA)
- Where
- Italy
- Volunteers
- 204 people
- Sponsor
- S.L.A. Pharma AG
Ileal Pouch-Anal Anastomosis
Ileal Pouch-Anal Anastomosis Registry
Little is known about the factors that predispose patients to complications after an ileal pouch-anal anastomosis procedure (IPAA).
- Trial name
- IPAA (NCT01026480)
- Where
- United States
- Volunteers
- 936 people
- Sponsor
- Boston Medical Center
Ulcerative Colitis, Ileal Pouch
MRI Anastomotic Integrity of Pelvic Intestinal Anastomoses
This protocol describes using an MRI-Enema technique to assess the integrity of colorectal anastomoses when compared to fluoroscopic water soluble contrast enema, and provides information the participant recruitment process…
- Conditions
- Ulcerative Colitis, Ileal Pouch, Anastomotic Leak
- Trial name
- NCT04719169
- Testing
- Dynamic MRI enema, Fluoroscopic enema
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- London North West Healthcare NHS Trust
Ulcerative Colitis, Inflammatory Bowel Diseases
Complications and Outcomes of Pouch Excision
Procedure is offered today to most patients with chronic ulcerative colitis (CUC) or familial adenomatous polyposis (FAP) who are candidates for total proctocolectomy.
- Trial name
- NCT03952195
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obesity, Ulcerative Colitis
A Study of Endoscopic Sleeve Gastroplasty for Obesity in Ulcerative Colitis
The purpose of this research is to gather information on the safety and effectiveness of Endoscopic Sleeve Gastroplasty (ESG) for weight loss in a population of obese UC patients undergoing colectomy with eventual IPAA.
- Trial name
- NCT05739162
- Testing
- Apollo Endoscopic Suture System, Lifestyle Intervention
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Ulcerative Colitis, Primary Sclerosing Cholangitis
Surgical Reconstruction in Ulcerative Colitis With Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) occurs in approximately 10 % of patients with ulcerative colitis (UC), but the outcome of reconstructive surgery is not clear.
- Conditions
- Ulcerative Colitis, Primary Sclerosing Cholangitis, Pouchitis, Complications
- Trial name
- NCT01798953
- Where
- Sweden
- Volunteers
- 175 people
- Sponsor
- Sahlgrenska University Hospital
Colon Anastomosis
Flexagon Plus OTOLoc Colon Anastomosis in Patients Undergoing Surgery
The primary objective of this trial is to investigate the safety and effectiveness of the Flexagon SFM system plus OTOLoc when used to create a Ileo-colic and Colo-colonic anastomoses in participants undergoing colon surgery.
- Trial name
- FOCUS (NCT06915818)
- Testing
- Ileo-colic and colo-colonic Anastomosis with Flexagon SFM and OTOLoc
- Where
- 2 sites in Chile, India
- Volunteers
- 65 people
- Sponsor
- GI Windows, Inc.
Colo-colonic Anastomoses, Ileo-colonic Anastomoses
Randomized Study Comparing Two Established Gastrointestinal Suture Techniques - One-layer-continuous Versus Double-layer-continuous Suture
The purpose of this study is to examine the frequency of postoperative complications depending on the number of suture layers in colo-colonic and ileo-colonic anastomoses Hypothesis: double-layer suture has less anastomotic…
- Trial name
- ANATECH (NCT00996554)
- Testing
- double layer-suture, Single-layer suture
- Where
- Germany
- Volunteers
- 252 people
- Sponsor
- Universitätsmedizin Mannheim
Ulcerative Colitis, Anti TNF Therapy
The Influence of Biologcal Treatment on the Short-Term Complications of Surgery in Patients With Inflematory Bowel Disease.
BACKGROUND: Previous studies of short-term surgical outcomes after preoperative exposure to anti-TNF therapy in ulcerative colitis (UC) patients who have undergone IPAA have been conflicting.
- Conditions
- Ulcerative Colitis, Anti TNF Therapy, Ileal Pouch Anal Anastomosis (IPAA)
- Trial name
- NCT03747068
- Testing
- Anti-TNF Drug
- Volunteers
- 130 people
- Sponsor
- HaEmek Medical Center, Israel
Anastomotic Leak, Colon Cancer
Leakage Rate of Ileo-COlic Sutured Anastomosis After Right Hemicolectomy
The primary aim of the study is to show that the ileo-colic anastomosis leakage rate until the first 30 days after surgery using MonoPlus® suture material for anastomosis construction after right hemicolectomy is not inferior to…
- Conditions
- Anastomotic Leak, Colon Cancer, Right Hemicolectomy
- Trial name
- LICOSARH (NCT07132970)
- Testing
- Monoplus Suture Material
- Where
- 4 sites in Germany
- Volunteers
- 249 people
- Sponsor
- Aesculap AG
Ulcerative Colitis, Postoperative Complications
TAMIS-IPAA vs. Lap-IPAA for Ulcerative Colitiis
The objective of this RCT is to compare the postoperative outcome of transanal versus transabdominal minimally invasive proctectomy with ileal pouch-annal anastomosis in patients with ulcerative colitis.
- Conditions
- Ulcerative Colitis, Postoperative Complications, Ileal Pouch
- Trial name
- NCT03536988
- Testing
- TAMIS-IPAA, Lap-IPAA
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Jinling Hospital, China
Ulcerative Colitis, Colorectal Cancer
Subjective Near-infrared Fluorescence Guidance in Perfusion Assessment of Ileal Pouch Formation and Ileal-pouch-anal Anastomosis
In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at three time points during ileal pouch…
- Conditions
- Ulcerative Colitis, Colorectal Cancer, Crohn Disease, Familial Adenomatous Polyposis
- Trial name
- NCT04695184
- Testing
- ICG-NIRF Imaging
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany