Clinical trials: Ileocolic Crohn Disease, open to volunteers
Crohn's Disease (CD)
Ultrasound-Guided Versus Standard Margin Selection in Ileocecal Resection of Terminal Ileal CD
This is a Phase II, single-center (Cleveland Clinic), two-arm, randomized, parallel-group superiority trial. The two arms will compare IOUS-guided margin selection against standard macroscopic margin selection in patients…
- Trial name
- SMILE-CD (NCT07680283)
- Testing
- IOUS-guided margin selection
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- The Cleveland Clinic
Crohn Disease
Comparing Hand-sewn (END-TO-END or Kono-S) to Stapled Anastomosis in Ileocolic Resection for Crohn's Disease
The aim of this multicenter randomised controlled trial is to compare the handsewn (end-to-end and Kono-S) to the stapled side-to-side ileocolic anastomosis after ileocolic resection for Crohn's disease with respect to 6 months…
- Trial name
- END2END (NCT05578235)
- Testing
- stapled side-to-side anastomosis, Handsewn anastomosis
- Where
- Netherlands
- Volunteers
- 165 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Crohn Disease
Safety of Mesentery-embedding Surgery in Patients With Ileocolic Crohn's Disease on Biotherapy
60% of patients with Crohn's disease will undergo surgery during their lifetime and without recurrence prevention treatment, 80% of patients will have an endoscopic recurrence within 1 year of surgery.
- Trial name
- RIC-2 (NCT06856044)
- Testing
- ileocolic resection with extended mesenteric resection
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Colo-rectal Cancer, Colo-rectal Surgery
Post Operative Hospital at Home After Colorectal Surgery
The goal of this feasibility study is to investigate whether a virtual Hospital at Home is safe and possible for patients undergoing planned minimally invasive colorectal surgery.
- Conditions
- Colo-rectal Cancer, Colo-rectal Surgery, Colocolic and Ileocolic Anastomosis, Colon and/or Rectal Resection With Anastomosis for Cancer
- Trial name
- POPHaH (NCT07113717)
- Testing
- virtual Hospital at Home
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Nordsjaellands Hospital
Endoscopic Recurrence Rate, After Ileocolic Crohn 's Disease Surgery
Mesenteric Surgical Margin for Crohn's Disease Endoscopic Recurrence
Despite significant advancements in the treatment of Crohn's disease (CD), approximately 50% of patients undergo surgical intervention within ten years of diagnosis.
- Trial name
- NCT06241170
- Testing
- mesentery-guided resection margin, traditional resection margin
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Crohn Disease (CD), Ileocolic Resection
Evaluation of Therapeutic Strategy to Prevent Crohn's Disease Endoscopic poSToperatIve recurreNce Based on earlY Dosage of Faecal Calprotectin
Crohn's disease (CD) (> 200,000 patients in France) is a chronic inflammatory disease that can lead to progression of intestinal destruction and impaired quality of life.
- Conditions
- Crohn Disease (CD), Ileocolic Resection, Post-endoscopic Operative Reccurence
- Trial name
- DESTINY II (NCT06972901)
- Testing
- Early faecal calprotectin dosage
- Where
- 8 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Clermont-Ferrand