Clinical trials: Ileostomy Closure
Ileostomy Closure in Rectal Cancer
Day-Case Closure of Loop Ileostomy in Rectal Cancer
The aim of this study is to investigate if day-case closure of ileostomy is feasible and safe.
- Trial name
- NCT02774447
- Testing
- ileostoma closure
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Low Anterior Resection Syndrome
The Effects of Colorectal Prehabilitation Via Reinfusion or Retention Enema of Ileal Contents Filtrate on the Defecation Functions for the LAR Patients With Ileostomy Before Stoma Closure
This study was a single-center RCT study to compare the effect of preoperative prehabilitation treatment of ileostomy contents filtrate reinfusion through distal ileocolon or retention of enema colon with that of traditional…
- Trial name
- NCT06569966
- Testing
- preoperative prehabilitation treatment of ileostomy contents filtrate reinfusion through distal ileocolon or retention of enema colon
- Where
- China
- Volunteers
- 154 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Wound Infection
A Randomized Trial of Ostomy Closure Techniques
Stoma closure has been associated with a high rate of surgical site infection (SSI). The rate for SSI following stoma closure has been noted to be 7-41%; a rate that is higher than expected for a clean-contaminated operative…
- Trial name
- NCT01713452
- Testing
- Purse string closure, Primary closure
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Minnesota
Ileostomy - Stoma
Early Closure of Protective Ileostomy in Rectal Cancer Patients
The aim of the study was to compare the restoration of the GI tract by the closure of protective ileostomy after low anterior resection for rectal cancer after 14 days and more than 3 months.
- Trial name
- ECPIS (NCT02997267)
- Testing
- Closure of the ileostomy
- Where
- Poland
- Volunteers
- 58 people
- Sponsor
- Stanley Dudrick's Memorial Hospital
Ileostomy
Early Temporary Stoma Closure After Proctectomy
We conducted a prospective randomized study to evaluate the results of early closure of temporary loop ileostomy at eight days in comparison with late closure at two months, after elective rectal resection with low pelvic…
- Trial name
- NCT00428636
- Testing
- ileostomy
- Where
- 3 sites in France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rectal Cancer, Total Mesorectal Excision
Timing Evaluation of Stoma Closure (TIMES). Early vs Late Closure of Stoma After Rectal Cancer Surgery.
The purpose of this study is to asses the safety and efficacy of early stoma closure (2-3 weeks after total mesorectal excision) vs late closure (16-24 weeks after mesorectal excision).
- Conditions
- Rectal Cancer, Total Mesorectal Excision, Ileostomy - Stoma, Ileostomy; Complications
- Trial name
- TIMES (NCT05284864)
- Testing
- Stoma closure
- Where
- 9 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Hospital Universitario La Fe
Colo-rectal Cancer, Colo-rectal Surgery
Post Operative Hospital at Home After Colorectal Surgery
The goal of this feasibility study is to investigate whether a virtual Hospital at Home is safe and possible for patients undergoing planned minimally invasive colorectal surgery.
- Conditions
- Colo-rectal Cancer, Colo-rectal Surgery, Colocolic and Ileocolic Anastomosis, Colon and/or Rectal Resection With Anastomosis for Cancer
- Trial name
- POPHaH (NCT07113717)
- Testing
- virtual Hospital at Home
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Nordsjaellands Hospital
Colorectal Diseases, Intestinal Diseases
Early Versus Delayed Ileostomy Closure Following Bowel Surgery
Temporary ileostomy is commonly created following bowel surgery to protect distal anastomoses and reduce the consequences of anastomotic leakage. However, the optimal timing for ileostomy closure remains controversial.
- Conditions
- Colorectal Diseases, Intestinal Diseases, Ileostomy
- Trial name
- EDIC (NCT07754227)
- Testing
- Early Ileostomy Closure, Delayed Ileostomy Closure
- Where
- Pakistan
- Volunteers
- 73 people
- Sponsor
- Dr. Waseem Ullah
Incisional Hernia
Prevention of Incisional Hernia With Biosynthetic Mesh at the Site of Temporary Ileostomy Closure (PRINCESS)
Prophylactic mesh reinforcement of the abdominal wall at the site of temporary ileostomy closure is effective in preventing postoperative incisional hernia.
- Trial name
- PRINCESS (NCT05400083)
- Where
- Italy
- Volunteers
- 203 people
- Sponsor
- Federico II University
Surgical Wound Infection
Trial to Reduce Wound Infection With Contralateral Drainage in Loop Ileostomy Closure
1. Introduction: The most common complication of loop ileostomies closure for rectal cancer patients undergoing a low anterior rectum resection, is the superficial surgical site infection (incidence 2-40%).
- Trial name
- NCT02574702
- Testing
- application of a contralateral drainage (Penrose ® device)
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Corporacion Parc Tauli
Rectal Cancer
Early Closure of Temporary Loop Ileostomy After Rectal Resection for Cancer
Early Closure of Temporary Loop Ileostomy After Rectal Resection for cancer
- Trial name
- NCT01865071
- Testing
- loop ileostomi
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Odense University Hospital
Diverting Ileostomy, Rectal Cancer
Purse-String Versus Linear Closure After Ileostomy Reversal
This randomized study compared two wound closure and wound care protocols after reversal of a diverting ileostomy in adults previously treated surgically for rectal cancer.
- Trial name
- NCT07892404
- Testing
- Linear Wound Management Protocol
- Where
- Ukraine
- Volunteers
- 23 people
- Sponsor
- Dnipro Regional Clinical Oncology Dispensary
Ileostomy - Stoma, Ileus
Efferent Loop Stimulation Previous to Ileostomy Closure. Ileostim Trial.
The loop ileostomy is an effective method used to bypass faecal contents and reduce the sequelae of possible anastomotic leakage.
- Conditions
- Ileostomy - Stoma, Ileus, Rectal Cancer, Surgical Complication
- Trial name
- Ileostim (NCT05302557)
- Testing
- Ileostomy stimulation
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Universidad de León
Rectum Cancer
PRELOOP Trial: Synthetic Versus Biological Mesh for Prevention of Incisional Hernia After Loop-ileostomy Closure
This study compares a synthetic mesh and biological implant in prevention of incisional hernia after loop-ileostomy closure.
- Trial name
- NCT03445936
- Testing
- Parietene Macro, Permacol
- Where
- 4 sites in Finland
- Volunteers
- 100 people
- Sponsor
- University of Oulu
Pouchitis, Ulcerative Colitis
Microbiota and Immune microEnvironment in Pouchitis
Microbiota and innate immunity in pouchitis: predisposing factors and modulation of the inflammation with probiotics. Around 20-25% of ulcerative colitis patients undergo restorative proctocolectomy with ileal pouch anal…
- Conditions
- Pouchitis, Ulcerative Colitis, Ileal Pouch
- Trial name
- MEP1 (NCT03136419)
- Testing
- Lactobacillus casei DG
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- University of Padova
Stoma Closure, Postoperative Pain
Revised-Paravertebral Nerve Blocks for Enhanced Recovery After Stoma Closure
After stoma closure, pain remains an important problem affecting patient recovery. A revised paravertebral block (r-PVB) was developed as a single-shot, large-volume intercostal-space injection performed at the exposed…
- Conditions
- Stoma Closure, Postoperative Pain, Quality of Recovery
- Trial name
- r-PVB III (NCT07571902)
- Testing
- Revised-Paravertebral Nerve Block
- Volunteers
- 250 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Incisional Hernia of Anterior Abdominal Wall
Phasix Mesh Underlay During Loop Ileostomy Closure
This prospective study will evaluate whether placement of long-acting absorbable Phasix mesh during loop ileostomy closure reduces the development of an incisional hernia at the ileostomy closure site in patients with a BMI…
- Trial name
- NCT07871630
- Testing
- Long-acting absorbable mesh
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Corewell Health West
Ileostomy, Rectal Cancer
The Stoma Closure Before or After Adjuvant Therapy Trial
This is an open-label multicenter controlled trial, including 28 centers from the Rete Oncologica (Oncological Network) of Piemonte and Valle d'Aosta in Italy (http://www.reteoncologica.it).
- Trial name
- STOMAD (NCT04372992)
- Testing
- Timing of stoma closure
- Where
- 28 sites in Italy
- Volunteers
- 14 people
- Sponsor
- Ospedale Umberto I di Torino
Ileostomy Stoma, Stoma Stimulation
Impact of Ambulatory Physiological Stimulation of the Efferent Limb Prior to Ileostomy Closure on Colorectal Microbiota Composition and Histopathological Findings
BACKGROUND Loop ileostomies are a type of stoma frequently used to protect high-risk colorectal anastomoses (surgical reconnection of the intestines), for example following rectal cancer resection.
- Conditions
- Ileostomy Stoma, Stoma Stimulation, Microbiome Analysis
- Trial name
- STIMIC (NCT07640113)
- Testing
- Serum stimulation, Physiological stimulation
- Volunteers
- 90 people
- Sponsor
- Hospital Clinic of Barcelona
Rectal Cancer
The Effect Of Probiotics On Bowel Function Restoration After Ileostomy Closure In Patients With Rectal Cancer
The study will investigate whether Probiotics(CJLP243) given just before and after ileostomy repair operation in patient with rectal cancer improve a bowel function.
- Trial name
- NCT02751736
- Testing
- CJLP243
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital