Clinical trials: Ileus Postoperative
Postoperative Ileus
Use of Beetroot Juice to Protect Against Postoperative Ileus (POI) Following Colorectal Surgery: a Pilot Study.
The BEET IT study investigates the possible protective effect of beetroot juice on POI following colorectal surgery in (partially) blinded single-center phase 2 randomized trial (pilot study).
- Trial name
- BEET IT (NCT03772444)
- Testing
- Beetroot juice, Nitrate-depleted beetroot juice, Water
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- University Hospital, Ghent
Ileus Postoperative
The Effects of Combined Gum-chewing and Parenteral Metoclopramide on Post-operative Ileus
A delay in the return of bowel function is a common occurrence after abdominal surgeries.1 The goal of this study was to test the effect of the combined use of chewing a gum and administering metoclopramide intravenously on the…
- Trial name
- NCT05669781
- Testing
- Metoclopramide 10mg, Gum and metoclopramide, Gum
- Where
- Nigeria
- Volunteers
- 105 people
- Sponsor
- Ikechukwu Bartholomew Ulasi
Postoperative Ileus
The Effect of Coffee Consumption in Enhancing Recovery of Bowel Function Following Colorectal Surgery.
The effects of coffee have been shown to act as a colonic stimulant. Caffeinated coffee stimulates colonic activity, most notably in the transverse/descending colon, in magnitude similar to a meal, 60% stronger than water, and…
- Trial name
- NCT02639728
- Testing
- Regular Coffee, Decaffeinated coffee, Warm water
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Cedars-Sinai Medical Center
Ileostomy; Complications, Bowel Obstruction
Implementing a Low Fiber Diet vs. Regular Diet in Postoperative Colorectal Patients With Ileostomies
The primary objective of this study is to prospectively evaluate rate of post-operative ileus or obstruction in patients with ileostomies receiving low fiber diet vs. regular diet starting post-operative day 1.
- Conditions
- Ileostomy; Complications, Bowel Obstruction, Postoperative Ileus
- Trial name
- NCT04675606
- Testing
- Regular diet, Low fiber diet
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Postoperative Ileus
Does Bowel Stimulation Before Loop Ileostomy Closure Reduce Postoperative Ileus?
Postoperative ileus is the most commonly observed morbidity following ileostomy closure. Studies have previously demonstrated that the defunctionalized bowel of a loop ileostomy undergoes a series of functional and structural…
- Trial name
- NCT02559635
- Testing
- Bowel stimulation, Nestle Resource
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- Jewish General Hospital
Postoperative Ileus
Gastric Volume and Colorectal Surgery
Postoperative ileus (POI) is a serious complication after colorectal surgery. One of its most frequent consequences is the replacement of nasogastric tube because of the vomiting.
- Trial name
- EVOL (NCT04461067)
- Testing
- ultrasonography
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Lumbar Spine Surgery Postoperative Ileus
Ileus After Lumbar Spine Surgery
Postoperative ileus (POI) after lumbar spine surgery is not uncommon. However, the incidence, severity and risk factors of ileus after spine surgery remain uncertain because there is not yet a prospective investigation using a…
- Trial name
- NCT04057599
- Where
- Taiwan
- Volunteers
- 156 people
- Sponsor
- National Taiwan University Hospital
Postoperative Ileus, Postoperative Nausea
Assessing Gastric Motility and Distention in Postoperative Gastrointestinal Surgery Using Bedside Gastric Ultrasound: Predicting Risk of Aspiration Pneumonia, Ileus, Return of Bowel Function
Point-of-care gastric ultrasound will be used to measure stomach contents postoperative in patients who underwent colorectal surgery.
- Conditions
- Postoperative Ileus, Postoperative Nausea, Postoperative Complications, Postoperative Nausea and Vomiting
- Trial name
- NCT04747691
- Testing
- Bedside gastric ultrasound
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eric Schwenk
Colorectal Disorders, Postoperative Ileus
Does Epidural Anesthesia Reduce Postoperative Ileus Following Colorectal Surgery?
The use of epidural analgesia (EA) has been suggested as an integral part of an enhanced recovery program for colorectal surgery. However, the effects of EA on postoperative ileus remain controversial.
- Trial name
- NCT04429425
- Testing
- epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Postoperative Ileus, Gastrointestinal Cancer
Acupuncture for the Treatment of Postoperative Ileus After Gastrointestinal Surgery
The goal of this study is to learn if electro-acupuncture is a feasible treatment option for postoperative ileus after abdominal surgery.
- Trial name
- NCT04713241
- Testing
- Electro-acupuncture, Standard of Care Bowel rest
- Sponsor
- Case Comprehensive Cancer Center
Postoperative Ileus
Subcutaneous Methylnaltrexone Versus Placebo for Postoperative Ileus Prevention
This randomized controlled trial will prospectively evaluate the clinical benefit for subcutaneous methylnaltrexone (MNTX) in counteracting the obstipatory (causing constipation) effects of spinal surgery without increasing…
- Trial name
- NCT03852524
- Testing
- Methylnaltrexone
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Ohio State University
Postoperative Ileus, Colorectal Surgery
Prucalopride in Postoperative Ileus
Postoperative ileus (POI) refers to the period of gut dysmotility that occurs after abdominal surgery. Patients with POI are unable to eat, suffer ongoing nausea and vomiting, are unable to open their bowels and have a prolonged…
- Conditions
- Postoperative Ileus, Colorectal Surgery, Postoperative Complications
- Trial name
- NCT02947269
- Testing
- Prucalopride
- Where
- New Zealand
- Volunteers
- 150 people
- Sponsor
- University of Auckland, New Zealand
Acupressure, Post-Op Complication
Effect of Acupressure on Recovery of Bowel Function in Patients Post Cesarean Section
Research objectives To compare the efficacy of acupressure with no acupressure to examine time to first flatus in patient post cesarean section ; Acupressure at ST-36 Zusanli (lateral to anterior crest of tibia, in the tibialis…
- Conditions
- Acupressure, Post-Op Complication, Cesarean Section, Bowel Ileus
- Trial name
- NCT04620850
- Testing
- Acupressure
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Postoperative Ileus, Bladder Cancer
Prucalopride for Postoperative Ileus in Patients Undergoing Robot-assisted Laparoscopic Radical Cystectomy
The first purpose is to determine whether prucalopride can promote the recovery of intestinal function after robot-assisted laparoscopic radical cystectomy and urinary diversion.
- Trial name
- NCT05001763
- Testing
- Prucalopride
- Volunteers
- 160 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Postoperative Ileus, Laparoscopic Colectomy Without Stoma Formation
Does Caffeine Reduce Postoperative Bowel Paralysis After Elective Colectomy?
Postoperative bowel paralysis is common after abdominal operations, including colectomy. As a result, hospitalization may be prolonged leading to increased cost.
- Conditions
- Postoperative Ileus, Laparoscopic Colectomy Without Stoma Formation, Colorectal Neoplasm, Diverticulitis
- Trial name
- CaCo (NCT02510911)
- Testing
- Caffeine (100 mg), Caffeine (200 mg), corn starch (250 mg approx.)
- Where
- 2 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- Thomas Steffen
Inflammatory Bowel Diseases, Dexamethasone
Perioperative Dexamethasone on Postoperative Outcome in IBD
The objective of this RCT is to determine the efficacy of a single preoperative dose of Dexamethasone for accelerating the recovery and reducing the incidence of postoperative complications in adult patients undergoing intestinal…
- Conditions
- Inflammatory Bowel Diseases, Dexamethasone, Postoperative Ileus, Postoperative Complications
- Trial name
- NCT03456752
- Testing
- Dexamethasone, Normal saline
- Where
- China
- Volunteers
- 302 people
- Sponsor
- Jinling Hospital, China
Postoperative Ileus
ANTERO-5: Gastric Motility in Postoperative Ileus
A monocenter, non-randomized interventional investigation in 3 panels of adult patients undergoing elective colorectal surgery who are at risk to develop postoperative ileus.
- Trial name
- ANTERO-5 (NCT04100265)
- Testing
- Panel 1 - High risk for postoperative ileus (VIPUN Gastric Monitoring System), Panel 2 - Postoperative ileus arm with investigational device (VIPUN Gastric Monitoring System)
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Postoperative Ileus
The Effect of Rocking Chair Movement on the Start of Bowel Functions in Patients With Gastrointestinal System Surgery
The Effect of Rocking Chair Movement on the Start of Bowel Functions in Patients With Gastrointestinal System Surgery The research will be carried out as a randomized controlled experimental study in patients with open…
- Trial name
- NCT04466319
- Testing
- Rocking Chair
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Eskisehir Osmangazi University
Postoperative Ileus
Effect of TU-100 in Patients Undergoing Laparoscopic Colectomy
TU-100 is a gastrointestinal drug produced from the three botanical raw materials, Asian ginseng, Zanthoxylum fruit (Japanese pepper), and ginger, based on proprietary aqueous decoction and granulation technology.
- Trial name
- TU100P2T3 (NCT02232893)
- Testing
- Daikenchuto (TU-100)
- Where
- 13 sites in United States
- Volunteers
- 69 people
- Sponsor
- Tsumura USA
Postoperative Ileus
Effects of Open and Laparoscopic Gastrointestinal Surgery on Gastrointestinal Function
A prospective study to compare the postoperative ileus in open and laparoscopic gastrointestinal surgery through the determination of the time the patient takes to pass flatus, pass stool, bowel movement, oral intake, the time of…
- Trial name
- NCT03887845
- Testing
- Surgery
- Where
- China
- Volunteers
- 401 people
- Sponsor
- West China Hospital