Clinical trials: Illicit Drug Use
HIV-1-infection
Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Patients With Active Illicit Substance usE
This study will evaluate the efficacy and safety of bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) in HIV-1 infected patients who actively use illicit substances.
- Trial name
- BASE (NCT03998176)
- Testing
- Bictegravir/emtricitabine/tenofovir alafenamide
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Nebraska
Mental Health Disorders, Substance Use Disorders
Supporting Treatment Access and Recovery Through Linkage and Support
This 3-year Hybrid Type 1 study will randomize 208 people with co-occurring substance use and mental health disorders (COD) referred from the Worcester Hub.
- Trial name
- STAR-LS (NCT05713695)
- Testing
- Full MISSION, Linkage Only Delivered by a Peer Specialist
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of Massachusetts, Worcester
Drug Abuse Illicit
Drug User Internet and Mobile Tech Use
The purpose of this exploratory study is to examine factors associated with frequency and type of internet and mobile technology use among illegal drug users, specifically use of internet and text-messaging to obtain health care…
- Trial name
- NCT01871298
- Testing
- Pilot Website Evaluation Component
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Columbia University
Drug Use Disorders, Illicit Drug Use
Digital Treatments for Opioids and Other Substance Use Disorders in Primary Care
The DIGITS Trial addresses a critical knowledge gap: How to best implement digital treatments for opioids and other substance use disorders in primary care.
- Conditions
- Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders, Opioid Use Disorder
- Trial name
- DIGITS (NCT05160233)
- Testing
- Standard implementation, Health Coaching, Practice Facilitation
- Where
- United States
- Volunteers
- 18,430 people
- Sponsor
- Kaiser Permanente
Substance Use Disorders, Illicit Drug Use
The Follow-up Study for the Patients of Illicit Substance Use Disorder
The patients will be diagnosed according to DSM-5, the severity of individual substance use disorder will be assessed, and the plan of treatment will be provided.
- Trial name
- NCT04426565
- Testing
- motivational enhancement interview, the individual psychotherapy, the group psychotherapy
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- Kaohsiung Kai-Suan Psychiatric Hospital
Tobacco Use, Alcohol Abuse
Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use- Electronic Spanish Platform
The goal of this study is to validate the TAPS-ESP as a screen and assessment that can be used in primary care for the screening and treatment of substance use.
- Conditions
- Tobacco Use, Alcohol Abuse, Prescription Drug Abuse, Substance Use
- Trial name
- TAPS-ESP (NCT05476588)
- Testing
- Screening
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Interference With Routine Analytical Tests, Stability of in Vitro Diagnostic Reagents
Interference and Stability Evaluation of the Intelligent Fingerprinting Drug Screening System
Prospective, open-label, double-dose, performance evaluation of interference effects and component stability of the Intelligent Fingerprinting Drug Screening System
- Conditions
- Interference With Routine Analytical Tests, Stability of in Vitro Diagnostic Reagents, Illicit Drug Use
- Trial name
- NCT07758907
- Testing
- Device storage condition, Interferent application
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Intelligent Bio Solutions Inc.
Drug Use Disorders, Addiction, Drug
A Electronic System to Improve Recovery Outcomes in Patients With Drug Use Disorder
Background: Relapse is very common in patients with illicit drug use disorder and contributes to a series of bad consequences that substantially impact patients' physical and social functions.
- Trial name
- NCT03451344
- Testing
- Integrated rehabilitation group, Community-based rehabilitation group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Mental Health Center
Drug-facilitated Sexual Assault
Characteristics of (Unwanted) Use of Alcohol and Illicit Substances Among Patients Reporting After Sexual Violence in Ghent: a Mono-centric Prospective Observational Study
This study aims at defining the patient characteristics and toxicological aspects of patients presenting at the sexual assault care centre with drugs-facilitated sexual assault.
- Trial name
- NCT06188780
- Testing
- urine/blood analysis with IA and LC-GCMS analysis
- Where
- Belgium
- Volunteers
- 114 people
- Sponsor
- University Hospital, Ghent
Substance Abuse, Risk Reduction
First Years Away From Home: Letting Go and Staying Connected
Alcohol abuse is the leading cause of death and serious injury among college students, and students also experience significant harms from other types of substance misuse and risk behaviors.
- Conditions
- Substance Abuse, Risk Reduction, RIsky Sexual Behavior
- Trial name
- FYAH:LGSC (NCT03227809)
- Testing
- Handbook condition, Handbook plus condition
- Where
- United States
- Volunteers
- 910 people, healthy volunteers welcome
- Sponsor
- Washington State University
Opiate Dependent, Previous Illicit Drug Use
Pupillometry and Pain Thresholds Patients Substituted by Methadone and Buprenorphine
The purpose is to study the relation between pupillary diameter measured under scotopic conditions, and the pain thresholds measured at the time of peak and residual effect of methadone/buprenorphine in opiate-dependent patients…
- Trial name
- PUPIDOL (NCT01560442)
- Testing
- Buprenorphine and Methadone Hydrochloride
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Substance Use Disorders
Repetitive Transcranial Magnetic Stimulation in Drugs Addiction
This study also aims to develop and apply a standard repetitive transcranial magnetic stimulation (rTMS) protocol on drug users.
- Trial name
- NCT06244329
- Testing
- Transcranial magnetic stimulation
- Where
- Hong Kong
- Volunteers
- 48 people
- Sponsor
- The Hong Kong Polytechnic University
Sexual; Sexual Desire, Illicit Drugs
Chemsex, Perceived Risks and Coping Strategies.
The research hypothesis is that access to prevention and harm and risk reduction associated with the use of psychoactive substances in a sexual context is insufficient for MSM practicing chemsex.
- Conditions
- Sexual; Sexual Desire, Illicit Drugs, MSM
- Trial name
- Chemsex (NCT04584229)
- Testing
- Intervention
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Montpellier
Drug Addiction, Polysubstance Addiction
Mapping And Preventing Relapse Risk in Polydrug Users
This Interventional two-arm comparative study will evaluate whether a mindfulness-based strategy (MBS) improves outcomes for adults with substance use disorders (polydrug users) compared with treatment-as-usual (TAU).
- Trial name
- NCT07161986
- Testing
- Mindfullness based Sobriety (MBS)
- Where
- Pakistan
- Volunteers
- 130 people
- Sponsor
- Institute of Psychology, Chinese Academy of Sciences
Chronic Pain
Managing Chronic Pain in Veterans With Substance Use Disorders
The proposed project will provide crucial data on the effectiveness of a pain management intervention designed for veterans with co-occurring pain and substance use disorders.
- Trial name
- NCT00982410
- Testing
- cognitive-behavioral treatment, educational supportive group
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- US Department of Veterans Affairs
Substance Abuse
Group Psychotherapy for Adolescents With Substance Use
Background: Substance abuse among children and adolescents is an important public health issue in Taiwan. Kaoshiung Chang Gung Memorial Hospital and Taiwan Kaoshiung Juvenile and Family Court will cooperate in a counseling…
- Trial name
- NCT02933125
- Testing
- Group psychotherapy, Standard supervision
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital
Substance Use, Criminal Recidivism
HOPE Demonstration Field Experiment Multisite Evaluation
The purpose of the Multisite Evaluation of the Honest Opportunity Probation with Enforcement Demonstration Field Experiment (the HOPE DFE Evaluation) is to conduct a randomized control trial (RCT) replication of the original…
- Trial name
- NCT01670708
- Testing
- HOPE, Probation as Usual
- Where
- 4 sites in United States
- Volunteers
- 1,504 people, healthy volunteers welcome
- Sponsor
- RTI International
Illicit Opioid Drug Use
Linking Opioid Dependent Patients From Inpatient Detoxification to Primary Care
The purpose of this study is to determine whether, for individuals in inpatient opioid detoxification, linking to outpatient Suboxone treatment increases treatment adherence and reduces relapse to illicit opioid use.
- Trial name
- NCT01751789
- Testing
- Linkage, Treatment as Usual
- Where
- United States
- Volunteers
- 335 people
- Sponsor
- Butler Hospital