Clinical trials: Illness, Chronic
Post-COVID-19 Syndrome, Long-COVID-19 Syndrome
Aerobic Training for Rehabilitation of Patients With Post Covid-19 Syndrome
Post-COVID-19 syndrome (PCS) occurs as a sequelae after acute infection with the SARS-CoV-2 virus (COVID-19 infection). PCS is defined as symptom persistence over a period of 12 weeks from infection and/or the appearance of new…
- Trial name
- NCT06016192
- Testing
- Aerobic Exercise Training
- Where
- Germany
- Volunteers
- 139 people
- Sponsor
- University of Witten/Herdecke
End Stage Renal Disease
Safety and Efficacy of Acthar Gel in an Outpatient Dialysis Population
This will be a prospective observational study of Acthar Gel in Non-Diabetic Hemodialysis [NDHD] patients receiving dialysis for ≤ 2 years.
- Trial name
- NCT02486744
- Testing
- Acthar Gel
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Youngstown State University
End Stage Renal Disease, Chronic Kidney Diseases
Ferric Citrate in ESRD Pilot Project
This research study is for participants that have End Stage Renal Disease (ESRD). ESRD is the last stage of chronic kidney disease.
- Trial name
- NCT03055598
- Testing
- Ferric Citrate
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Sreedhar Mandayam
Pulmonary Disease, Chronic Obstructive, Asthma
Efficacy and Safety of 4 Weeks Treatment With Inhaled BI 1744 CL in Patients With COPD.
The primary objective of this study is to determine the optimum dose(s) of BI 1744 CL inhalation solution delivered by the Respimat® inhaler for four weeks in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00452400
- Testing
- BI 1744CL
- Where
- 42 sites in United States, Canada and 2 more
- Volunteers
- 409 people
- Sponsor
- Boehringer Ingelheim
COPD
Appropriate Admission in COPD Exacerbation From Emergency Department. Multicenter Study
Objectives: To estimate the rate of appropriate hospital admissions , and of discharge to home episodes that would have been appropriate admissions to the hospital, on patients with exacerbations of their COPD by using…
- Trial name
- IRYSS-COPD (NCT02434536)
- Volunteers
- 2,487 people
- Sponsor
- Hospital Galdakao-Usansolo
Peripheral Arterial Disease
ILLUMENATE Below-The-Knee (BTK) Arteries: a Post Market Clinical Study
The objective of this prospective, multi-center, single arm study is to obtain further data on the safety and performance of the StellarexTM 0.014" OTW Drug-coated Angioplasty Balloon in the treatment of lesions in "below the…
- Trial name
- BTK PMS (NCT03395236)
- Testing
- StellarexTM 0.014" Over-The-Wire Drug-coated Angioplasty Balloon
- Where
- 10 sites in Germany, Netherlands and 1 more
- Volunteers
- 49 people
- Sponsor
- Spectranetics Corporation
Chronic Kidney Disease Stage 1, Chronic Kidney Disease Stage 2
The Effect of Vitamin D3 Supplementation on Hepcidin and Ferritin Serum Levels in Children With Chronic Kidney Disease
The goal of this clinical trial is to analyze the effects of in vitamin D3 on serum hepcidin and ferritin levels among children with chronic kidney disease.
- Trial name
- NCT06706271
- Testing
- Vitamin D
- Where
- Indonesia
- Volunteers
- 43 people
- Sponsor
- Hasanuddin University
Adult Acute Promyelocytic Leukemia (M3), Blastic Phase Chronic Myelogenous Leukemia
PS-341 in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia in Blast Phase, or Myelodysplastic Syndrome
Phase I trial to study the effectiveness of PS-341 in treating patients who have refractory or relapsed acute myeloid leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia in blast phase, or myelodysplastic syndrome.
- Conditions
- Adult Acute Promyelocytic Leukemia (M3), Blastic Phase Chronic Myelogenous Leukemia, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia
- Trial name
- NCT00005064
- Testing
- bortezomib
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Chronic Hepatitis C, Insulin Resistance
NIDDM and IR in Combination Therapy for CHC
The influence of insulin sensitivity and glucose tolerance on the effects of antiviral therapy for HCV remains unclear. The aim of the present study was (1) To elucidate the clinical and virological factors associated with…
- Trial name
- NCT00687999
- Testing
- pegylated interferon alpha and ribavirin
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Hypertension
The Effect of Modular Education on Individuals Diagnosed With Hypertension
Aim:This study focused on patients with hypertension to investigate the effect of a nurse-led counseling program on their self-efficacy and disease adherence.
- Trial name
- NCT06816732
- Testing
- Nurse-led Modular Training
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ulviye Özcan Yüce
Chronic Myeloid Leukemia
Observational Study on Dose Optimization of Olverembatinib in Patients With Chronic Myeloid Leukemia in Chronic or Accelerated Phase
This study is a multicenter observational study aimed to investigate the efficacy and safety of olverembatinib dose reduction to 20 mg every other day (QOD) in patients with chronic myeloid leukemia (CML) in chronic phase or…
- Trial name
- NCT07383298
- Testing
- Olverembatinib 20mg
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Qian Jiang
Chronic Renal Failure
Identification of Cardiovascular Risk Factors Linked to Renal Failure Progression
The aim of this study is to appreciate the influence of renal failure progression on vasculopathy (coronary calcifications and left ventricular hypertrophy) and cardiovascular risk factors.
- Trial name
- Pre-HD (NCT00608998)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Montpellier
Chronic Kidney Diseases, Diabetes Mellitus, Type 2
Curcumin on NFE2L2 Gene Expression, Antioxidant Capacity and Renal Function According to rs35652124 in Diabetic Nephropathy
The increase in the prevalence of diabetes mellitus (DM) is one of the greatest public health challenges worldwide. Epidemiological studies have shown that DM is the leading cause of chronic kidney disease (CKD) in patients…
- Conditions
- Chronic Kidney Diseases, Diabetes Mellitus, Type 2, Polymorphism
- Trial name
- CURCUNRF2 (NCT03262363)
- Testing
- Curcumin/NFE2L2 A>G
- Where
- Mexico
- Volunteers
- 176 people
- Sponsor
- Unidad de Investigacion Medica en Enfermedades Renales
Chronic Obstructive Pulmonary Disease (COPD)
Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations.
The purpose of this Phase III study is to evaluate the efficacy and safety of tozorakimab Dose 1 and Dose 2 administered subcutaneously (SC) in adult participants with symptomatic COPD and history of ≥ 2 moderate or ≥ 1 severe…
- Trial name
- TITANIA (NCT05158387)
- Testing
- Tozorakimab
- Where
- 212 sites in United States, Australia and 18 more
- Volunteers
- 1,172 people
- Sponsor
- AstraZeneca
Hepatitis B, HBV
Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic, Hepatitis B e Antigen-negative Subjects Infected With HBV Virus and Receiving or Stopping Treatment With a NUC Inhibitor
An open-label, Phase 2, exploratory study to examine the safety and efficacy of inarigivir in non-cirrhotic, hepatitis B e antigen (HBeAg)-negative subjects with chronic HBV infection.
- Conditions
- Hepatitis B, HBV, Hepatitis B, Chronic
- Trial name
- NCT04023721
- Testing
- Inarigivir soproxil, Nucleoside/nucleotide (NUC) analogue inhibitors
- Where
- 7 sites in Canada, United Kingdom
- Volunteers
- 64 people
- Sponsor
- F-star Therapeutics, Inc.
Chronic Myeloid Leukemia
Telemonitoring Study - for Chronic Myeloid Leukemia (CML)
This study is being conducted in a population of patients with chronic phase Chronic Myeloid Leukemia (CML) to learn more about how patients follow prescribed regimens for taking oral cancer drugs.
- Trial name
- NCT01490983
- Testing
- no access to eMedonline, eMedonline access
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- Rex Cancer Center, Raleigh, NC
Familial Cold Urticaria
The Use of Kineret (Anakinra) in the Treatment of Familial Cold Urticaria
An open labelled trial of Kineret (anakinra) induction therapy (100mg./day) in over a four week period in the treatment of Familial Cold Urticaria.
- Trial name
- NCT00214851
- Testing
- Kineret (anakinra)
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Nova Scotia Health Authority
Respiratory Tract Infections, Chronic Bronchitis
KEYS: Study Comparing Clinical Health Outcomes of Telithromycin Versus Azithromycin in Outpatients With Community-acquired Lower Respiratory Tract Infections
The purpose of this study is to determine if 1 course of antibiotic treatment with telithromycin is superior to azithromycin in the treatment of lower respiratory tract infections (LRTIs), acute exacerbations of chronic…
- Conditions
- Respiratory Tract Infections, Chronic Bronchitis, Pneumonia
- Trial name
- KEYS (NCT00132951)
- Testing
- Telithromycin, Azithromycin
- Where
- 2 sites in United States, Canada
- Volunteers
- 2,051 people
- Sponsor
- Sanofi
Kidney Failure, Chronic, Kidney Transplantation
Safety of Immunosuppression Minimization in Children and Adolescents After Kidney Transplantation
Kidney transplantation is widely considered to be the treatment of choice for children with End Stage Renal Disease (ESRD). The purpose of this study is to determine the safety of sirolimus monotherapy for long-term…
- Conditions
- Kidney Failure, Chronic, Kidney Transplantation, Immunosuppression
- Trial name
- NCT00768729
- Testing
- Sirolimus, MMF or Azathioprine
- Where
- 5 sites in United States
- Volunteers
- 7 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Chronic Renal Failure, Urinary Extracellular Vesicle
Extracellular Vesicles as Biomarkers for Chronic Renal Failure
The recent discovery of extracellular vesicles (EV) as a mechanism of intercellular communication has made it possible to develop a new field of health research and could bring new information on the pathological mechanisms of…
- Trial name
- VE-IRC (NCT04700631)
- Testing
- urinary extracellular vesicle concentration, blood sample
- Where
- France
- Volunteers
- 143 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
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