Clinical trials: Illness, Chronic
Proteinuria, Kidney Injury
Inflammatory and Immune Profiling of Kidney Tissue Obtained From Patients With Newly Diagnosed Kidney Disease
This study will evaluate in patients with kidney disease, the role that certain inflammatory and immune mediators play in promoting kidney damage.
- Conditions
- Proteinuria, Kidney Injury, Chronic Kidney Disease
- Trial name
- NCT01156428
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- The Rogosin Institute
End Stage Renal Disease
Conventional Hemodialysis vs. Short Daily Hemodialysis (6 Days / Week) and Mechanisms of Blood Pressure Control
More than 80% of patients with end stage renal disease have hypertension; 70% of whom are poorly controlled using conventional Hemodialysis therapy.
- Trial name
- NCT00759967
- Testing
- Microneurography, Bioimpedance testing
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Ottawa Hospital Research Institute
Asthma Bronchiale, COPD
Investigation of the Respiratory Profile of Patients With Obstructive Pulmonary Disease (ASTHMA, COPD)
The primary aim of the OPTIPULM study is the evaluation of recorded pulmonary function curves and, based on them, the computer modelling of lung deposition for the individually used or potentially applicable inhalation drugs.
- Trial name
- OPTIPULM (NCT06966271)
- Where
- 7 sites in Hungary
- Volunteers
- 150 people
- Sponsor
- Tradeflex Ltd
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Mud Bath Therapy in Chronic Obstructive Pulmonary Disease
Rehabilitation and physical therapy strategies targeting extra pulmonary manifestations of Chronic Obstructive Pulmonary Disease (COPD)are far from being well defined.
- Trial name
- NCT01253941
- Testing
- Mud bath Therapy
- Where
- 2 sites in Italy
- Volunteers
- 42 people
- Sponsor
- Fondazione Salvatore Maugeri
Chronic Pancreatitis
Validation Of Chronic Pancreatitis Prognosis Score (COPPS)
Clinical course of chronic pancreatitis is still unpredictable, due to the lack of clinical classification. There is no model to assess disease severity or progression or predict patient outcomes.
- Trial name
- NCT04907266
- Testing
- Structured Questionnaire
- Where
- India
- Volunteers
- 177 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Chronic Obstructive Pulmonary Disease, Type 2 Diabetes Mellitus
The Early Predictors for Developing Type 2 Diabetes Mellitus in Patients With Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease(COPD), characterized by persistent airflow limitation, associated with an progressive chronic inflammatory response of the lung to noxious particles or gases, can lead to dyspnea and limited…
- Trial name
- NCT03152994
- Testing
- Checking fasting blood glucose(FBG)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Zhujiang Hospital
COPD, HEAD&NECK CANCER,SCREENING
Prevalence of Malignant and Premalignant Lesions in the Head & Neck in Patients With Chronic Obstructive Pulmonary Disease
Head and neck cancers usually occur in patients who have a history of long tobacco use. Chronic obstructive pulmonary disease (COPD) is a chronic progressive disease of the airways and lung parenchyma that is also associated with…
- Trial name
- NCT02333812
- Testing
- Stroboscopic nasopharyngeal laryngoscopy
- Volunteers
- 250 people
- Sponsor
- Hadassah Medical Organization
Chronic Myeloproliferative Disorders, Graft Versus Host Disease
Immunologic Diagnostic Blood Test in Predicting Side-Effects in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Other Diseases
RATIONALE: Studying a diagnostic biomarker test in blood samples from patients who have undergone a donor stem cell transplant for cancer may help doctors plan treatment.
- Conditions
- Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Infection, Leukemia
- Trial name
- NCT00813501
- Testing
- immunosuppressive therapy, immunological diagnostic method, allogeneic hematopoietic stem cell transplantation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- City of Hope Medical Center
Chronic Obstructive Pulmonary Disease
Compliance of Long-term Home Non-invasive Ventilation for Patients With Chronic Obstructive Pulmonary Disease
Background : Long-term home non-invasive ventilation (NIV) can be proposed as treatment for acute respiratory failure with severe alveolar hypoventilation.
- Trial name
- NCT04333901
- Where
- 8 sites in France
- Volunteers
- 25 people
- Sponsor
- Vivisol
Pulmonary Disease, Chronic Obstructive, Respiratory Insufficiency
Сohort Study to Evaluate Exacerbations, Respiratory Symptoms, Physical Exercise Intolerance and Lung Functions Among Participants Who Use IQOS With Heatsticks Compared to Smokers of Conventional Cigarettes
This study evaluates frequency of exacerbations, respiratory symptoms, physical exercise intolerance and abnormal lung functions among participants who use IQOS with heatsticks compared to smokers of conventional cigarettes
- Conditions
- Pulmonary Disease, Chronic Obstructive, Respiratory Insufficiency, Physical Disability, Respiratory Disease
- Trial name
- NCT03383601
- Testing
- Heated Tobacco product IQOS/heatstick, Smoking combustible cigarettes
- Where
- Kazakhstan
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Kazakhstan Academy of Preventive Medicine
Chronic Obstructive Pulmonary Disease, Urinary Incontinence
Urinary Incontinence Amongst Women With Chronic Obstructive Pulmonary Disease
The primary aim of the study is to investigate whether pelvic floor muscle training or cough-suppression therapy reduces symptoms of urinary incontinence amongst women with chronic obstructive pulmonary disease grade 1-4 (mild to…
- Trial name
- UriCO (NCT02614105)
- Testing
- Pelvic floor muscle training, Cough-suppression therapy, Control
- Where
- 2 sites in Norway
- Volunteers
- 35 people
- Sponsor
- Ostfold Hospital Trust
Heart Failure, Copd
The DIVERT-CARE (Collaboration Action Research & Evaluation) Trial
Rationale: In Canada, home care clients are a large and expanding subgroup of medically complex older adults with relatively poor access to effective chronic disease management.
- Trial name
- DIVERT-CARE (NCT03012256)
- Testing
- Cardio-respiratory management model
- Where
- 3 sites in Canada
- Volunteers
- 896 people
- Sponsor
- McMaster University
COPD
HFNC During Bronchoscopy in COPD Patients
Bronchoscopy diagnosis and treatment is highly irritating, and the effect of local topical anesthesia is poor; the airway is shared; and COPD patients have low oxygen reserves due to impaired lung function.
- Trial name
- HFNC COPD (NCT07850856)
- Testing
- group N used traditional nasal cannula for oxygen inhalation, Group HFNC used nasal high-flow oxygen inhalation.
- Volunteers
- 1,000 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Head and Neck Neoplasms
Customized Registry Tool for Tracking Adherence to Clinical Guidelines for Head and Neck Cancers
To implement and evaluate a health information technology platform designed to support the management of patients with head and neck cancer in an urban, publicly-funded outpatient setting.
- Trial name
- NCT03546322
- Testing
- Registry
- Where
- United States
- Volunteers
- 802 people
- Sponsor
- University of California, San Francisco
End Stage Renal Disease, Hemodialysis Access Failure
Acoustic Analysis of VA Sounds
End-stage renal disease (ESRD) is a growing global health problem, strictly connected with progressive ageing population and longer survival of patients living on renal replacement therapy.
- Trial name
- VAsound (NCT05612022)
- Testing
- AVF creation, AVG creation
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Kidney Failure, Chronic
Can Intravenous Vitamin C Improve Skin Hyperpigmentation in Long-Term Hemodialysis Patients?
Intravenous vitamin C may improve skin hyperpigmentation in chronic hemodialysis patients
- Trial name
- NCT00172302
- Testing
- vitamin C, intravenous injection
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
COPD, Aging
D Vitamine and Whole Body Vibration in Functional Outcomes
Older with Chronic obstructive Pulmonary Disease (COPD) were submitted to chronic whole body vibration training during 03 months, receiving a vitamine D dose for each week or placebo vitamine.
- Trial name
- NCT03684837
- Testing
- Vitamine D supplementation, chronic exercise in whole body vibration (WBV)
- Where
- Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Maíra F Pessoa
Peritoneal Dialysis, Kidney Failure, Chronic
Exercise in Peritoneal Dialysis Patients (PDEX)
Patients with end-stage kidney disease (ESKD) receiving peritoneal dialysis (PD) are physically inactive, resulting in poor physical function and reduced quality of life.
- Trial name
- PDEX (NCT03980795)
- Testing
- Exercise Program
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Satellite Healthcare
Hepatitis D, Chronic
A Study of Pegylated Interferon (PEG-IFN) Alfa-2a (Pegasys) in Participants With Chronic Hepatitis D (CHD)
This study evaluated the efficacy and safety of 48-week treatment with pegylated interferon (PEG-IFN) alfa-2a (Pegasys) monotherapy in participants with chronic hepatitis D (CHD).
- Trial name
- NCT02732639
- Testing
- Pegylated Interferon (PEG-IFN) alfa-2a
- Where
- 7 sites in Romania
- Volunteers
- 31 people
- Sponsor
- Hoffmann-La Roche
Chronic Hepatitis C
Multiple Ascending Dose Study of BMS-929075 in Hepatitis C Virus (HCV) Infected Patients
The purpose of this study is to determine the change from baseline in HCV Ribonucleic acid (RNA) on Day 4 following three days of dosing with BMS-929075 in chronically genotype subtype 1a and 1b HCV infected subjects
- Trial name
- NCT01525212
- Testing
- BMS-929075
- Where
- 3 sites in Australia
- Sponsor
- Bristol-Myers Squibb
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