Clinical trials: Illness Behavior
Critical Illness, Oncology
Giving Information Systematically and Transparently in Lung and GI Cancer Phase 2
When advanced disease progresses, there comes a time when an oncologists must explain to their patients that they only have months left to live.
- Conditions
- Critical Illness, Oncology, Communication
- Trial name
- Oncolo-GIST (NCT04179305)
- Testing
- Oncolo-GIST, Usual Care Arm
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Weill Medical College of Cornell University
Nicotine Addiction, Serious Mental Illness
Feasibility Trial of a Tailored Smoking Cessation App for People With Serious Mental Illness
Quitting smoking has important health benefits for people with serious mental illness, more than half of whom are smokers. Smoking reductions in this population, in turn, could contribute to saving billions of dollars in…
- Trial name
- NCT03069482
- Testing
- Learn to Quit App, Nicotine patch, Nicotine lozenge
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Duke University
Depression
Preventing Depression in People Receiving Mechanical Ventilation in an Intensive Care Unit
This study will determine the effectiveness of antidepressant medication in preventing depression and improving recovery in people who have been supported by mechanical ventilators in an intensive care unit (ICU).
- Trial name
- NCT00872027
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Minnesota
COPD, Heart Failure
Personalized Experiences to Inform Improved Communication for Minorities With Life Limiting Illness
The purpose of this research is to develop patient-centered palliative care interventions to improve patient-provider communication and Quality of Life (QoL) of ethnic and racial minority patients living with life-limiting…
- Conditions
- COPD, Heart Failure, Cancer
- Trial name
- NCT03391115
- Testing
- Storytelling Intervention for Patient Participants, Storytelling Intervention for Nurse Participants
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Medication Adherence, Self Efficacy
The Influence of a Medication Adherence Smartphone Application on Medication Adherence in Chronic Illness
Medication adherence is a critical aspect of achieving optimal health outcomes. Thirty to 50% of patients adhere to long-term medication treatment of chronic diseases.
- Trial name
- NCT05098743
- Testing
- Medisafe smartphone mobile application, Printed medication list
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Vanderbilt University
Critical Illness, Oncology
Giving Information Systematically and Transparently in Lung and GI Cancer Phase 1
When advanced disease progresses, there comes a time when an oncologists must explain to their patients that they only have months left to live.
- Conditions
- Critical Illness, Oncology, Communication
- Trial name
- Oncolo-GIST (NCT04158908)
- Testing
- Oncolo-GIST
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
Psychological Distress, Depression
Mobile Mindfulness to Improve Psychological Distress After Critical Illness
Many survivors of the intensive care unit (ICU) suffer from persistent symptoms of depression, anxiety, and post-traumatic stress disorder (PTSD).
- Conditions
- Psychological Distress, Depression, Anxiety, Post-traumatic Stress Disorder
- Trial name
- NCT02701361
- Testing
- mobile mindfulness, standard mindfulness, education
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Duke University
Mental Disorders
Integrated Care & Patient Navigators for Latinos With Serious Mental Illness
The health care needs of people with serious mental illness are exacerbated by ethnic health disparities. Latinos with serious mental illness show significant health problems compared to other ethnic groups.
- Trial name
- NCT02469714
- Testing
- Peer Navigator Intervention
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Illinois Institute of Technology
Chronic Pain, Schizophrenia
Assessment and Treatment for Chronic Pain in Veterans With Serious Mental Illness
Chronic pain has a highly negative impact on Veterans, especially those with serious mental illness (SMI). Chronic pain leads to poorer mental health and physical functioning, and represents a critical obstacle to rehabilitation…
- Conditions
- Chronic Pain, Schizophrenia, Psychotic Disorders, Bipolar Disorder
- Trial name
- CPSMI (NCT04118283)
- Testing
- Cognitive Behavioral Therapy for Chronic Pain, Health and Wellness
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- VA Office of Research and Development
COVID-19, Cardiorespiratory Failure
Lift Mobile Mindfulness for COVID-19 Distress Symptoms
This is a randomized clinical trial (RCT) nested within the NIH PETAL Network's COVID cohort study (BLUE CORAL [Biology and Longitudinal Epidemiology: COVID Observational Study]) of patients hospitalized for COVID-19-related…
- Trial name
- LIFTCOVID (NCT04581200)
- Testing
- Lift
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Duke University
Mental Disorders, Mental Health Services
Cognitive Behavior Therapy for Work Success in Veterans With Mental Illness: A Pre-post Efficacy Study
In 2010, 11.5% of all Gulf War-II Veterans were unemployed; that figure rose to 15.2% in January 2011 and continues to grow as the number of Veterans from recent wars increases.
- Trial name
- NCT01918774
- Testing
- Cognitive behavior therapy for work success (CBTw)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- VA Office of Research and Development
Mental Illness Persistent
Efficacy of Mental Health Self-Directed Care Financing
Self-directed care (SDC) programs give people with disabilities control over public funds to purchase traditional behavioral health and non-traditional services in order to remain outside of institutional settings.
- Trial name
- SDC-RCT (NCT03582813)
- Testing
- Self-directed care, Services as usual
- Volunteers
- 216 people
- Sponsor
- University of Illinois Chicago
Psychosocial Deprivation, Work-Related Stress
Family Supportive Supervisor Training and Workplace Assessment Tool
This study will evaluate the effectiveness of FSST 2.0 (family supportive supervisor training plus support for use of family and sick leaves) using a randomized control trial design.
- Conditions
- Psychosocial Deprivation, Work-Related Stress, Life-work Imbalance
- Trial name
- FSST (NCT05080426)
- Testing
- Family Supportive Supervisor Training 2.0
- Where
- United States
- Volunteers
- 1,175 people, healthy volunteers welcome
- Sponsor
- Work Life Help
Gulf War Veterans Illness, Neurobehavioral Manifestations
Scalp Application of LED Therapy to Improve Thinking and Memory in Veterans With Gulf War Illness
The purpose of this study is to learn if an experimental treatment can help thinking ability, and memory in Veterans with Gulf War Veterans Illnesses (GWVI).
- Conditions
- Gulf War Veterans Illness, Neurobehavioral Manifestations, Memory Disorders
- Trial name
- NCT01782378
- Testing
- Real LED Treatment
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- VA Office of Research and Development
Cardiorespiratory Failure
Mobile Coping Skills Training to Improve Cardiorespiratory Failure Survivors' Psychological Distress
This is a pilot randomized clinical trial involving adult survivors of cardiorespiratory failure treated in intensive care units (ICUs) that is designed to test the acceptability, feasibility, and clinical impact of a coping…
- Trial name
- Blueprint (NCT04329702)
- Testing
- Coping skills training mobile app with call from CST therapist, Coping skills training mobile app only
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Duke University
Mental Disorders
Efficacy of the Recovery Workbook as a Psychoeducational Tool for Facilitating Recovery
The present study will determine if Spaniol and colleague's (1994) Recovery Workbook group intervention is an effective clinical tool to move a person with SMI along in their journey of recovery.
- Trial name
- NCT00375167
- Testing
- Recovery Workbook Training (psychoeducational training), ACT as usual
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Queen's University
Smoking Cessation
Smoking Cessation After Hospitalization for a Cardiopulmonary Illness
Smoking-related cardiopulmonary diseases account for a large number of hospital admissions. We investigated the efficacy of hypnotherapy as an aid to a counseling-based smoking cessation program in improving quit rates of…
- Trial name
- STOPP (NCT01791803)
- Testing
- hypnotherapy, Nicotine
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- North Shore Medical Center
Bipolar Disorder, Schizophrenia
Novel Pharmacotherapy Approaches in Smokers With Serious Mental Illness
Approximately 60 chronic smokers with bipolar disorder, schizophrenia or schizoaffective disorder who are motivated to try to quit smoking will be randomized to receive smoking cessation treatment with the FDA-approved…
- Conditions
- Bipolar Disorder, Schizophrenia, Schizoaffective Disorder, Nicotine Dependence
- Trial name
- NCT04011280
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of California, San Diego
Discrimination, Racial, Communication
PRISM Race and Communication Pilot RCT
This is a pilot randomized trial of 60 patients to test feasibility, acceptability and efficacy of PRISM to improve resilience and facilitate improved patient-clinician communication in racially minorities patients with serious…
- Conditions
- Discrimination, Racial, Communication, Chronic Illness, Bias, Racial
- Trial name
- NCT04915079
- Testing
- Promoting Resilience in Stress Management (PRISM)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Washington
Caregivers, Parents
Self-Management in Parents of Technology-Dependent Children
Parent caregivers of children with chronic conditions who require life-saving technology such as mechanical ventilation or feeding tubes must maintain a high level of vigilance 24 hours a day, 7 days a week.
- Conditions
- Caregivers, Parents, Self-Management, Chronic Illnesses, Multiple
- Trial name
- NCT04105244
- Testing
- Resourcefulness Training©
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center