Clinical trials: Image Guidance
Prostate Cancer
Rectal Spacer for Prostate Cancer Radiation Image Guidance
The purpose of the study is to determine if a radiopaque hydrogel rectal spacer, SpaceOAR Vue®, can be used in place of fiducial markers when aligning patients for radiotherapy.
- Trial name
- NCT05650021
- Testing
- SpaceOAR Vue
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Milton S. Hershey Medical Center
ICH - Intracerebral Hemorrhage, IVH- Intraventricular Hemorrhage
Placing External Ventricular Drains Using Assistive Augmented Reality or Image-Based Localization
The goal of this clinical trial is to assess if EVD placement using augmented reality is non inferior to image-guidance systems for assistance in adult patients needing an EVD for spontaneous ICH with IVH or severe TBI.
- Conditions
- ICH - Intracerebral Hemorrhage, IVH- Intraventricular Hemorrhage, TBI Traumatic Brain Injury
- Trial name
- PEARL (NCT07042048)
- Testing
- EVD placement - image-guidance assisted, EVD placement - AR assisted
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cooper Health System
Magnetic Resonance Imaging
MR Guidance for Liver and Pancreas
This is a single centre, single arm, prospective feasibility study that aims to see whether magnetic resonance imaging (MRI) as a source of image guidance before each radiation treatment fraction is feasible, and also if it may…
- Trial name
- NCT03582189
- Testing
- MRI
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Liver Cancer, Hepatocellular Carcinoma
I-FIGS Feasibility Study
Background: Removal of part of the liver (resection) is performed as a treatment for some cancers in the liver. To achieve the best possible outcomes, it is important that the cancer is removed completely (R0 resection) (1).
- Conditions
- Liver Cancer, Hepatocellular Carcinoma, Liver Metastasis Colon Cancer
- Trial name
- I-FIGS (NCT05616039)
- Testing
- Standard Liver Surgery, Indocyanine Fluorescent Image Guided Surgery (I-FIGS)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University Hospital Plymouth NHS Trust
Prostate Cancer
The Use of Transperineal Ultrasound for Radiation Therapy Treatment Planning and Image Guidance in the Treatment of Prostate Cancer
This study is being done to find out if transperineal ultrasound (TPUS) can help define the prostate gland for radiation treatment planning and improve upon current methods of image guidance for the treatment of prostate cancer.
- Trial name
- NCT01545154
- Testing
- Transperineal Ultrasound
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- H. James Wallace, MD
Localized Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8
Computed Tomography-Guided Stereotactic Body Radiation Therapy With Intrafraction Motion Monitoring for the Treatment of Localized Prostate Cancer, ILLUSION Trial
This clinical trial studies the side effects of computed tomography (CT)-guided stereotactic body radiation therapy (SBRT) with intrafraction motion monitoring and to see how well it works in treating patients with prostate…
- Conditions
- Localized Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8
- Trial name
- ILLUSION (NCT06995053)
- Testing
- Biospecimen Collection, Computed Tomography, CT-guided Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Colorectal Cancer, Metastatic to the Liver
Utility of Intra-operative Image Guidance System for Missing Metastases
Intraoperatively, the surgeon will interrogate the liver with ultrasound. The time spent by the surgeon using the ultrasound is recorded.
- Trial name
- NCT02806037
- Volunteers
- 25 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Post Operative Analgesia, Non-inferiority Trial
Efficacy of Transversus Abdominis Plane (TAP) Block Techniques: Surgeon vs Anesthesia - Ultrasound Guidance
The transversus abdominis plane (TAP) block is a regional anesthesia technique where local anesthetic is injected into the neurovascular plane between the transversus abdominis and internal oblique muscles.
- Trial name
- NCT03577912
- Testing
- TAP block administered by Surgery, TAP block administered by Anesthesia
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Radiation Injuries
Novel Wireless Mixed Reality Headset for Image Guidance in Cardiac Catheterization Laboratory
Our hypothesis is that improved line of sight to patient data, ergonomics, and headset lead shielding in the CCL will lead to behavioral changes in the CCL personnel that will reduce radiation exposure to all members of the team.
- Trial name
- MRCCL (NCT05063773)
- Testing
- Mixed reality heads up display
- Volunteers
- 150 people
- Sponsor
- SG Devices LLC
Prostate Cancer
Focal Laser Ablation of Prostate Cancer: A Feasibility Study Using MRI/US Image Fusion for Guidance
This is an open-label feasibility/pilot study to evaluate the safety and feasibility of the FocalPoint System with UnfoldAI. In this study, the investigators intend to use the UnfoldAI software to identify cancer margins and…
- Trial name
- NCT06047509
- Testing
- Focal Laser Ablation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Abdominal Cancer, Thoracic Cancer
Validate the Safety and Feasibility of the CT-guided Interventional Robot in Percutaneous Biopsy Procedure.
This multicenter, randomized controlled trial aims to investigate whether the interventional robot can be well and safely used for percutaneous needle biopsy compared with the freehand needle biopsy method under CT guidance in…
- Trial name
- NCT06484764
- Testing
- CT-fluoroscopy guided robot-assisted biopsy of thoracic and abdominal lesions, Freehand CT-guided percutaneous needle biopsy of thoracic and abdominal lesions
- Where
- 3 sites in China
- Volunteers
- 166 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Prostate Cancer, Prostatic Neoplasm
Prostate SBRT for Locally Recurrent Prostate Cancer After Prior Radiotherapy
Background: Prostate cancer is the second leading cause of cancer death in United States (U.S.) men. Radiation is an effective treatment for most patients with localized prostate cancer, but sometimes the tumor returns.
- Trial name
- NCT03253744
- Testing
- 18F-DCFPyL, Tumor Irradiation, Prostate + tumor irradiation
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Cancer Institute (NCI)
Esophagogastric Cancer
PET-MRI Esophagus Feasibility Study
This is a single arm, single centre, investigator initiated study to investigate the feasibility of using PET-MRI imaging in radiation treatment workflow in up to 15 patients with esophagogastric cancer.
- Trial name
- PET-MRI (NCT05796102)
- Testing
- PET-MRI
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University Health Network, Toronto
Renal Tumor, Renal Cancer
A CCafU-UroCCR Randomized Trial: 3D Image-Guided Robot-AssisTEd Partial Nephrectomy for Renal Complex Tumor (UroCCR N°99)
The goal of this clinical trial is to evaluate peri and post-operative outcomes as well as long-term survival of 3D IGRAPN compared to conventional Robot-Assisted Partial Nephrectomy (RAPN) for moderate and highly complex renal…
- Trial name
- ACCURATE (NCT05572216)
- Testing
- Robot assisted partial nephrectomy with 3D image guidance
- Where
- 2 sites in France
- Volunteers
- 694 people
- Sponsor
- University Hospital, Grenoble
Posttraumatic Stress Disorder
Multimodal Image Analysis and Guidance of Neuromodulation for Trauma-Related Symptoms
MAGNETS is a prospective, randomized, parallel-design, sham-controlled clinical trial of accelerated, functional magnetic resonance imaging (fMRI)-guided intermittent theta burst stimulation (iTBS) to the right dorsolateral…
- Trial name
- MAGNETS (NCT06449326)
- Testing
- Active Intermittent theta burst stimulation
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- University of New Mexico
Liver Biopsy, Lung Biopsy
Novel Guidance Device for Image Fusion and Needle Guidance in Lung, Liver or Kidney Biopsy
This study investigates whether a new image fusion technology can reduce patient radiation dose from CTs and/or procedure time during biopsies of lung, liver or kidney.
- Conditions
- Liver Biopsy, Lung Biopsy, Kidney Biopsy
- Trial name
- NCT04039529
- Testing
- SCENERGY-guided Biopsy
- Where
- United States
- Sponsor
- Clear Guide Medical
Prostate Cancer
Focal Laser Ablation of Prostate Tissue
This is an open-label pilot, feasibility/exploratory study to evaluate the safety of laser interstitial thermal therapy (LITT) using Visualase in the focal ablation of prostate tissue and to gather data for the design of future…
- Trial name
- FLA (NCT02357121)
- Testing
- Focal Laser Ablation
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Echocardiography, Transesophageal, In-hospital Cardiac Arrest
RescueTEE for In-hospital Cardiac Arrest (ReTEECA Trial)
ReTEECA Trial. Rescue TransEsophageal Echocardiography for In-Hospital Cardiac Arrest. This trial is aimed at studying the utility and interventional outcomes of rescue transesophageal echocardiography (RescueTEE) to aid in…
- Conditions
- Echocardiography, Transesophageal, In-hospital Cardiac Arrest, Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation
- Trial name
- ReTEECA (NCT04220619)
- Testing
- Tranesophageal Echocardiography
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Breast Cancer
Precision Breast Conserving Surgery With Guidance.
From 2021 to 2022, 31 patients with unifocal breast cancer were enrolled for precision breast conserving surgery (PBCS) guided by wire guided localization (WGL) combined with CT guided 3D reconstruction.
- Trial name
- NCT05708664
- Testing
- precision breast conserving surgery guided by wire guided localization combined with MDCT guided 3D reconstruction
- Where
- China
- Volunteers
- 92 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Soft Tissue Sarcoma of the Limb, AJCC Stage II and III
Preoperative Radiotherapy for Sarcomas of the Extremities With Intensity-Modulation, Image-Guidance and Small Safety-margins
RATIONALE: Modern radiotherapy techniques in a neoadjuvant setting have the potential to minimize morbidity and maximize efficacy.
- Trial name
- PREMISS (NCT01552239)
- Testing
- IMRT/IGRT, Tumor resection, Brachytherapy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Technical University of Munich