Clinical trials: Image Reconstruction
Breast Cancer
Therapeutic Nipple Sparing Mastectomy.
This is a phase III, multicentric, single arm study with a sequential design using the exact conditional Poisson test. The primary objective of this prospective study is to evaluate whether selected breast carcinoma patients…
- Trial name
- MAPAM-01 (NCT02311959)
- Testing
- Nipple sparing mastectomy
- Where
- 33 sites in France
- Volunteers
- 450 people
- Sponsor
- Institut Claudius Regaud
Alveolar Bone Resorption
Radiographic and Histological Evaluation of Regenerated Bone After Grafting Using Allograft Shell and Autogenous Chips
The clinical cases in the present study described the khoury shell technique using an allograft plate and autogenous chips, for horizontal reconstruction of the anterior alveolar ridge in the esthetic zone.
- Trial name
- Shell grafting (NCT04324697)
- Testing
- Horizontal alveolar bone augmentation
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- October 6 University
Breast Cancer, Reconstructive Surgery
The BREASTrial:Breast Reconstruction Evaluation Using Acellular Dermal Matrix as a Sling Trial
Primary Hypothesis: 1. Alloderm and Dermamatrix have comparable complication rates when used for staged breast reconstruction Secondary hypotheses: 1.
- Trial name
- NCT00872859
- Testing
- Implantation of Dermal Matrix substitute
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Utah
Anterior Cruciate Ligament Reconstruction
Effectiveness of Kneehab in Strengthening Quadriceps in Rehabilitation Post Anterior Cruciate Ligament (ACL) Reconstruction
Prospective, controlled, randomized, single blind study in patients undergoing rehabilitation following anterior cruciate ligament reconstruction. 96 patients were randomly assigned to one of three groups.
- Trial name
- NMES (NCT00738010)
- Testing
- Kneehab, Poli-Stim, Control
- Where
- Germany
- Volunteers
- 131 people
- Sponsor
- Bio-Medical Research, Ltd.
AC Joint Dislocation
Arthroscopic Coracoclavicular Ligament Reconstruction Comparing Two Techniques
This study follows early wound healing using knot hiding titanium implants in coracoclavicular ligament reconstruction. A further aim is to compare two techniques where the semitendinosus tendon graft either runs through the…
- Trial name
- NCT03887234
- Testing
- Coracoclavicular ligament reconstruction
- Where
- Finland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Turku
Patellar (or Kneecap) Instability and Mal-alignment, Patellar Dislocation
MPFL Reconstruction Versus Rehabilitation
This study involves patients between the ages of 16 and 25 and have been diagnosed with a first-time traumatic patellar dislocation within the past 3 months.
- Trial name
- ANTI-GLIDE (NCT06926699)
- Testing
- Medial Patellofemoral Ligament Reconstruction, Rehabilitation
- Sponsor
- McMaster University
Ankle Disease, Ankle (Ligaments); Instability (Old Injury)
Is Harvesting the Peroneus Brevis an Alternative in Anatomic Ankle Ligament Reconstruction
Severe ankle sprains are the most frequent reason for emergency trauma consultations. Between 30% and 80% of sprains result in sequelae such as pain, joint derangement or instability.
- Trial name
- NCT06655350
- Testing
- MRI, Measure
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pain
Bupivacaine Pain Pumps to Decrease Mastectomy Post-Operative Pain
This double-blind, randomized, controlled clinical trial comparing patient-reported pain and pain medication/narcotic use between patients randomized to treatment (bupivacaine) or placebo (saline) delivered via pain pump to the…
- Trial name
- NCT01494259
- Testing
- Bupivacaine, Saline
- Where
- United States
- Sponsor
- Johns Hopkins University
Breast Cancer, Radiation Fibrosis
Autologous Fat Grafting in Radiated Soft Tissue Reconstruction
The purpose of this study is to observe the effect of autologous fat grafting on soft tissue reconstruction of the breast following radiation treatment.
- Conditions
- Breast Cancer, Radiation Fibrosis, Fat Grafting
- Trial name
- NCT05890196
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Chicago
Vertebral Compression Fractures, Osteoporotic Vertebral Compression Fractures
Circumferential Vertebral Reconstruction of Osteoporotic Compression Fractures Using a Novel Bipedicular Peek Implant
The RECONSTRUCT study is a multi-center, prospective, single arm, post-market, pilot study to evaluate clinical and radiologic outcome data regarding the use of the Vertebral Implant PEEK (VIP) implant in the treatment of…
- Trial name
- RECONSTRUCT (NCT05337696)
- Testing
- Vertebral Implant PEEK Procedure, Vertebral Implant PEEK (VIP) implant
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Atherosclerosis, Coronary
Fluid-dynamics in Bifurcation PCI
Investigator-initiated, international, multicentre, observational study with two cohorts. The two study cohorts will be: Cohort A: to understand if the local blood flow patterns (associated with low WSS), as evaluated by…
- Trial name
- FORECAST (NCT03174418)
- Testing
- Coronary angiography and optical coherence tomography
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Catholic University of the Sacred Heart
Cruciate Ligament Rupture, Cartilage Injury
The Treatment of Cartilaginous Lesions and Concomitant Anterior Cruciate Ligament Reconstruction
The aim of the study is the evaluation of both clinical and radiological results in patients undergone to cruciate ligament reconstruction with concomitant cartilaginous lesion treated with or without nanofractures.
- Trial name
- NCT04184687
- Testing
- Nanofractures, no treatment cartilaginous lesions
- Where
- Italy
- Volunteers
- 4 people
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament Reconstruction
Effect of PRP Versus BMC in Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) is an important stabilizer of knee during daily activity and exercise. The ruptured ACL need to be reconstructed by a new tendon graft which passed the bone tunnel and joint during operation.
- Trial name
- NCT05191732
- Testing
- Platelet-Rich Plasma; Bone marrow concentrate
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Endodontic Disease, Root Canal Infection
3D Analysis of Root Canal Conformation
Aim To evaluate in vivo the shaping ability of the canal with 3 different single-file systems: Reciproc Blue, WaveOne Gold and XP Endo-Shaper, using cone beam computed tomography and 3D reconstructions to measure canal volume…
- Trial name
- NCT03680534
- Testing
- Root canal preparation
- Where
- Colombia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institucion Universitaria Colegios de Colombia
Breast Cancer, Breast Reconstruction
Single-Stage Prepectoral Placement of Textured Implants Using a Polyester Mesh Endoprostheses With Fluoropolymer Coating in Patients With Breast Cancer
This study aims to evaluate the efficacy of using a polyester mesh endoprosthesis with a fluoropolymer coating in reducing postoperative complications, particularly protrusions, following subcutaneous mastectomy with simultaneous…
- Conditions
- Breast Cancer, Breast Reconstruction, Coated Materials, Reconstruction Breast Surgery
- Trial name
- FluoropolyMesh (NCT07185334)
- Testing
- Subcutaneous mastectomy using a fluoropolymer-coated polyester mesh endoprosthesis with simultaneous prepectoral placement of textured implants., Subcutaneous mastectomy with simultaneous prepectoral placement of textured implants.
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Saint Petersburg State University, Russia
Benign Breast Neoplasm, Breast Carcinoma
MR Correlated Spectroscopic Imaging for Diagnosing Breast Cancer
This trial studies how well an imaging technique called magnetic resonance (MR) spectroscopic imaging works in identifying breast cancer in women with benign or suspicious areas in the breast.
- Conditions
- Benign Breast Neoplasm, Breast Carcinoma, Malignant Breast Neoplasm
- Trial name
- NCT06090630
- Testing
- Diffusion Weighted Imaging, Magnetic Resonance Spectroscopic Imaging
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
the Severity and Duration of Intraoperative Hypotension
Applying HPI in Oral Cancer Surgery
Investigating HPI effect in oral cancer surgery
- Trial name
- NCT07405892
- Testing
- HPI, HPI silence
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Breast Reconstruction
Impact of Pectoral Versus Paravertebral Blocks on Pain and Physical Well-Being in Implant-Based Breast Reconstruction
The broad aim of this study is to compare the effectiveness of paravertebral and pectoral blocks on pain and physical well-being of patients undergoing immediate implant-based breast reconstruction.
- Trial name
- NCT07209436
- Testing
- Paravertebral block (single injection), Pectoral block
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- Amy Colwell
Lung Cancer, Thoracic Surgery, Video-Assisted
3D Lung Reconstructions Using Open-source Software for Lung Cancer Surgery
Preoperative three-dimensional (3D) lung reconstructions can reduce intraoperative blood loss, conversion rate, and operation duration.
- Conditions
- Lung Cancer, Thoracic Surgery, Video-Assisted, Lobectomy, Segmentectomy
- Trial name
- 3D-LUNG (NCT06132607)
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- Erik de Loos
Breast Reconstruction, Neurotization
Effect of Neurotization on QoL and Sensory Restoration
This is a single-site, randomized, double-blinded trial to assess whether neurotization following autologous breast reconstruction in patients with breast cancer increases quality of life and sensation in the breast compared to…
- Trial name
- NCT05206565
- Testing
- Neurotization - Autologous Reconstruction with DIEP/TRAM
- Sponsor
- University of Wisconsin, Madison
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