Clinical trials: Image-Guided Surgery
Retinal Diseases, Fuchs Endothelial Dystrophy
DISCOVER Study: Microscope-integrated Intraoperative OCT Study
Optical coherence tomography (OCT )provides high resolution information regarding the anatomic structure of the tissues of the eye in a cross-sectional and 3 dimensional view.
- Conditions
- Retinal Diseases, Fuchs Endothelial Dystrophy, Macular Hole, Epiretinal Membrane
- Trial name
- DISCOVER (NCT02423213)
- Where
- United States
- Volunteers
- 2,911 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Sentinel Lymph Node, Breast Cancer
Application of Surgical Navigation System in Sentinel Lymph Node of Breast Cancer Research
The purpose of this study is to compare the sentinel lymph node (SLN) detection rate of early breast cancer patients between using Indocyanine green (ICG) and Methylene blue with a novel surgical navigation system.
- Trial name
- NCT02084784
- Testing
- Indocyanine green, methylene blue
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Chinese Academy of Sciences
NEC, Atresia
Safety and Feasibility of Indocyanine Green Fluorescence for Intraoperative Assessment of Intestinal Perfusion in Young Infants and Neonates
The goal of this clinical trial is to test the use of the SPY-PHI device for the purpose of ICG-mediated intestinal perfusion visualization during gastrointestinal surgery in neonates and young infants (<3 months old) undergoing…
- Conditions
- NEC, Atresia, Malrotation, Intestinal Perforation
- Trial name
- IMAGINE (NCT05734118)
- Testing
- Perfusion assessment by means of the SPY-PHI camera
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
Hip Fractures, Anesthesia Local
Suprasacral Parallel Shift - Ultrasound/MR Image Fusion Guided Lumbosacral Plexus Block
The main objective of the trial is to complete a double-blinded randomized controlled trial with crossover design of a lumbosacral plexus block with the Suprasacral Parallel Shift technique guided by ultrasound/magnetic resonance…
- Conditions
- Hip Fractures, Anesthesia Local, Pain, Perioperative
- Trial name
- NCT02593370
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Thomas F. Bendtsen
Osteoarthritis Knee Pain
Revised Targets for Knee Radiofrequency Ablation
This research team is doing a study to learn more about a new way to treat long-term knee pain caused by joint damage. They are using a treatment called radiofrequency ablation (RFA).
- Trial name
- ReTaKRA (NCT06934421)
- Testing
- Ultrasound-Guided Genicular Nerve Radiofrequency Ablation
- Where
- 2 sites in Portugal
- Volunteers
- 60 people
- Sponsor
- Centro Hospitalar Universitario do Algarve
Gynecologic Cancer, Cervical Cancer
Intraoperative Microscopic Assessment of Lymph Node Status in Gynecological Malignancies
The IMAGINE study is a monocentric, observational, prospective study evaluating the diagnostic performance of Full-Field Optical Coherence Tomography (FF-OCT) combined with Dynamic Cell Imaging (DCI) (Van Gogh System, AQUYRE…
- Conditions
- Gynecologic Cancer, Cervical Cancer, Endometrial Cancer, Ovary Cancer
- Trial name
- IMAGINE (NCT07702721)
- Volunteers
- 160 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Liver Cancer
Evaluation of a Minimally Invasive Image-Guided Surgery System for Hepatic Ablation Procedures
This study was designed in two phases: Phase I is designed to confirm that the surgeon is able to perform accurate liver surface registration including standard liver features used as landmarks during a scheduled laparoscopic…
- Trial name
- NCT01238666
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Pathfinder Therapeutics
Hepatocellular Carcinoma
ITGA6 Targeting NIR-II Fluorescence Image Guided Surgery
In this study, the investigators will detect hepatocellular carcinoma lesions using fluoescence imaging with ITGA6 targeting probes during tumor resection surgery.
- Trial name
- NCT06204835
- Testing
- RD-Cy7 fluorophore
- Where
- 2 sites in China
- Volunteers
- 90 people
- Sponsor
- Institute of Automation, Chinese Academy of Sciences
Hypoparathyroidism Postprocedural, Hypocalcemia
Near Infrared (NIR) Autofluorescence Image-guided Thyroid Surgery
The objective of this ongoing randomized controlled trial is to examine whether the use of intra-operative NIR(near infrared) camera can reduce the number of patients who experience transient or persistent hypoparathyroidism…
- Conditions
- Hypoparathyroidism Postprocedural, Hypocalcemia, Surgery--Complications
- Trial name
- NCT04193332
- Testing
- NIR optical imaging camera
- Where
- 2 sites in Denmark
- Volunteers
- 214 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hepatocellular Carcinoma
Computer-assisted Tumor Ablation for Patients With Liver Cancer
In patients with primary liver cancer arising from the liver cells, several treatment options are available according to the stage of the disease.
- Trial name
- NCT03630068
- Testing
- Stereotactic percutaneous image-guided microwave ablation
- Where
- Switzerland
- Volunteers
- 87 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Breast Cancer
Feasibility and Identification of Breast Cancer Patients for Potential Avoidance of Surgery
The goal of this clinical research study is to compare the use of an ultrasound-guided biopsy with what is found during surgery in finding evidence of the disease.
- Trial name
- NCT02455791
- Testing
- Ultrasound-Guided Biopsy
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- M.D. Anderson Cancer Center
Sensorineural Hearing Loss
Clinal Evaluation of Navigation Based Functional Ear Surgery Using Image Guided and Robotically Assisted Techniques
To assess the feasibility of achieving a minimally invasive access to the inner ear through the navigation-based HEARO procedure and subsequently insert the electrode array of the cochlear implant through the access.
- Trial name
- EAR2OS (NCT03746613)
- Testing
- HEARO
- Where
- Belgium
- Volunteers
- 3 people
- Sponsor
- Prof. Vedat Topsakal
Lung Neoplasm
Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy
Patients with stage I non-small cell lung cancer have been historically treated with surgery whenever they are fit for an operation.
- Trial name
- VALOR (NCT02984761)
- Testing
- Stereotactic Radiotherapy, Anatomic Pulmonary Resection
- Where
- 17 sites in United States
- Volunteers
- 670 people
- Sponsor
- VA Office of Research and Development
Fluorenscent Image Guided Surgery, Indocyanide Green
Intra-gallbladder or Systemic Indocyanide Green Injection Facilitate Cholecystectomy.
The investigators will collect the pre-operative medical history and arrange physical examination, life quality evaluation, blood and biochemical test.
- Trial name
- NCT03024892
- Testing
- ICG GB, ICG IV, LC conventional
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- Chang Gung Memorial Hospital
CT-guided Minimally Invasive Procedures e.g., Biopsies
Evaluation of the Safety, Effectiveness & Usability of the XACT Robotic System for Image Guided Percutaneous Procedures
This is a prospective, single-arm study is to evaluate the safety, effectiveness and usability of the XACT device. Subjects undergoing CT-guided, minimally invasive percutaneous procedures in the interventional radiology suite…
- Trial name
- NCT03008603
- Testing
- XACT Robotic System
- Where
- 2 sites in United States, Israel
- Volunteers
- 60 people
- Sponsor
- Xact Robotics Ltd.
Feasibility of Video Augmentation System, Value of Video Augmentation Navigation
A Feasibility Study of a Modular Video Augmentation System for Image-Guided Skull Base Surgery
Current standard of care for complex head, neck and skull base surgery require navigation systems that allow instruments to be tracked optically or electromagnetically while registered to a patient's pre-operative X-ray computed…
- Trial name
- NCT01591954
- Testing
- Video Augmentation
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Liver Cancer
Feasibility of a Minimally Invasive Image-Guided Surgery System for Hepatic Procedures
This study was designed in two phases: Phase I is designed to confirm that the surgeon is able to perform accurate liver surface registration including standard liver features used as landmarks during a scheduled laparoscopic…
- Trial name
- NCT01286428
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Pathfinder Therapeutics
Penile Cancer, Margin Assessment
Image Guided Penile Cancer Surgery
The main treatment modality for Penile Squamous Cell Carcinoma (PSCC) is surgery with curative intent. In organ sparing surgery a tumor-positive margin of up to 36% exist.
- Trial name
- GLANS (NCT05376202)
- Testing
- Cetuximab-IRDye800CW
- Where
- Netherlands
- Volunteers
- 11 people
- Sponsor
- University Medical Center Groningen
Orthopaedic Trauma, Hip Fracture
Image Guided System for Orthopaedic Surgery
This project focuses on the further development and clinical testing of an image-guided surgical system. The system will help surgeons perform procedures that involve inserting a screw, guide pin, drill bit, or other straight…
- Trial name
- NCT00022802
- Testing
- Image-guided surgical system
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Gastric Cancer
Image-guided Minimally Invasive Robotic Surgery Using Preoperative CT Scan for Gastric Cancer Patients
The purpose of this study is to assess the feasibility of image-guided surgery in patients with early stage gastric cancer using Robotic Surgery with Tile-pro program.
- Trial name
- NCT01338948
- Testing
- preoperative 3D-CT reconstruction
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Yonsei University