Clinical trials: Imaging, Diagnostic
ACL Tears
MRI Evaluation of Graft Maturation Following ACL Reconstruction
Post-surgical ACL Graft maturation will be assessed at 4.5, 6, 7.5, 9, 10.5, and 12 months with MRI.
- Trial name
- NCT07046000
- Testing
- MRI
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Skye Biologics Holdings, LLC
Central Airway Stenosis
Vibration Response Imaging (VRI) in Patients That Are Undergoing Pulmonary Interventional Procedure
Vibration response imaging (VRI) technology, provides a radiation-free dynamic image of the lung, by visualizing vibration energy emitted during the respiration cycle (lung sounds).
- Trial name
- NCT00672893
- Testing
- Vibration Response Imaging
- Where
- 5 sites in United States, France and 2 more
- Volunteers
- 200 people
- Sponsor
- Deep Breeze
Bronchiolitis Obliterans, Lung Transplant Rejection
Prospective Study for Transplant Optimization Using Functional Imaging (TROFI)
The objective of this study is to detect BOS in an early stage by using the outcome parameters generated by Functional Respiratory Imaging (FRI).
- Trial name
- NCT02488304
- Testing
- HRCT scans
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- FLUIDDA nv
Neoplasms of the Prostate
An Extension Study MRI/US Fusion Imaging and Biopsy in Combination With Nanoparticle Directed Focal Therapy for Ablation of Prostate Tissue
To determine the efficacy of using MRI/US fusion imaging technology to direct focal ablation of prostate tissue using nanoparticle-directed laser irradiation.
- Trial name
- NCT04240639
- Testing
- AuroShell particle infusion
- Where
- 8 sites in United States
- Volunteers
- 60 people
- Sponsor
- Nanospectra Biosciences, Inc.
Prostate Cancer (Adenocarcinoma)
Registry to Evaluate Long-Term Outcomes in Patients Who Undergo 68-Ga-PSMA-11 PET/CT Imaging Evaluations
The purpose of this observational research registry is to understand the real-world use of Illuccix PET/CT in prostate cancer, and how results from this testing impact patient's treatment and prostate cancer journey over time.
- Trial name
- NCT06655064
- Testing
- None- Observational
- Where
- 9 sites in United States
- Volunteers
- 120 people
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Limited
Lung Structure Determination
A Comparison of Technegas and Xenon-133 Planar Lung Imaging in Subjects Referred for Ventilation Scintigraphy
Phase 3 within-subject non-inferiority trial of Technegas ventilation imaging compared to Xenon-133 (Xe-133) ventilation imaging to demonstrate the non-inferiority of Technegas compared to Xe-133 ventilation studies with respect…
- Trial name
- NCT03054870
- Testing
- Xe-133, Technegas
- Where
- 9 sites in United States
- Volunteers
- 226 people
- Sponsor
- Cyclomedica Australia PTY Limited
NSCLC, NSCLC (Advanced Non-small Cell Lung Cancer)
A Study of [225Ac]Ac-AKY-2519 in Patients With B7-H3 Expressing Solid Tumors
This is a Phase 1b, 2-part, multi-center, open-label study to evaluate the safety, tolerability, dosimetry, and pharmacokinetics (PK) of [64Cu]Cu-AKY-2519 and/or [225Ac]Ac-AKY-2519, as well as the preliminary anti-tumor activity…
- Conditions
- NSCLC, NSCLC (Advanced Non-small Cell Lung Cancer), ES-SCLC, Small Cell Lung Cancer Extensive Stage
- Trial name
- BActinium-2 (NCT07887971)
- Testing
- [225Ac]Ac-AKY-2519 (therapeutic), [64Cu]Cu-AKY-2519 (imaging)
- Where
- 2 sites in United States
- Volunteers
- 152 people
- Sponsor
- Aktis Oncology, Inc.
Prostate Cancer
Study to Evaluate 99mTc-MIP-1404 SPECT/CT Imaging in Men With Biopsy Proven Low-Grade Prostate Cancer
99mTc-MIP-1404 is a radioactive diagnostic imaging agent indicated for imaging men with newly diagnosed prostate cancer whose biopsy indicates a histopathologic Gleason Score of ≤ 3+4 severity who are candidates for active…
- Trial name
- proSPECT-AS (NCT02615067)
- Testing
- 99mTc-MIP-1404 Injection, Whole-Body Planar and pelvic SPECT/CT scan
- Where
- 45 sites in United States, Canada
- Volunteers
- 531 people
- Sponsor
- Molecular Insight Pharmaceuticals, Inc.
Prostate Cancer, Prostate Cancer (Adenocarcinoma)
A Single-Arm, Blinded, Fluorescent PSMA Histopathology Trial of AS1986NS
A Single-Arm, blinded, fluorescent PSMA histopathology trial of AS1986NS
- Conditions
- Prostate Cancer, Prostate Cancer (Adenocarcinoma), Fluorescence Imaging
- Trial name
- LUMA-PSMA (NCT06906471)
- Testing
- AS1986NS
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Antelope Surgical Solutions, Inc
Prostate Cancer
This Study Evaluates the Diagnostic Performance and Safety of 68Ga-NYM032 PET/CT Imaging in Patients With Suspected Recurrence of Prostate Cancer.
This study evaluates the diagnostic performance and safety of 68Ga-NYM032 PET/CT imaging in patients with suspected recurrence of prostate cancer.
- Trial name
- NCT07649122
- Testing
- 68-Ga-NYM032
- Where
- 2 sites in China
- Volunteers
- 232 people
- Sponsor
- Norroy Bioscience Co., LTD
Infertility
Eeva System Imaging Study
The purpose of this clinical trial is to collect imaging data on embryos followed to blastocyst stage (Day 5-6) for ongoing development and validation of the Eeva System.
- Trial name
- PROSPECT (NCT02301637)
- Testing
- Eeva™ Test
- Where
- 7 sites in United States, New Zealand
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Progyny, Inc.
Deep Vein Thrombosis, Venous Thrombosis
A Randomized, Open-Label, Parallel-Group, Multi-Center Study for the Evaluation of Efficacy and Safety of Edoxaban Monotherapy Versus Low Molecular Weight (LMW) Heparin/Warfarin in Subjects With Symptomatic Deep-Vein Thrombosis
Assess the relative change in thrombus volume as determined by two assessments (Baseline and Day 14-21) with magnetic resonance venography (MRV) in subjects with deep-vein thrombosis (DVT) treated with either an edoxaban…
- Trial name
- eTRIS (NCT01662908)
- Testing
- edoxaban tosylate, enoxaparin/unfractionated heparin, warfarin
- Where
- 34 sites in United States, Canada
- Volunteers
- 85 people
- Sponsor
- Daiichi Sankyo
PET Imaging in Patients With Prostate Cancer
Phase I/II Clinical Study of HRS-1738 for the Diagnosis of Prostate Cancer Patients
This study aims to evaluate the safety and pharmacokinetics of HRS-1738 injection in adult patients with prostate cancer.
- Trial name
- NCT07056439
- Testing
- HRS-1738 Injection
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Diagnostic Imaging
Magnevist Post-marketing Surveillance in Japan
This study is a regulatory post-marketing surveillance in Japan, and it is a local prospective and observational study of patients who have received Magnevist at a dose of more than 0.2 ml/kg for MR angiography of peripheral…
- Trial name
- NCT01376739
- Testing
- Gadopentetate dimeglumine (Magnevist, BAY86-4882)
- Where
- Japan
- Volunteers
- 2,051 people
- Sponsor
- Bayer
Diabetic Retinopathy, Retinal Imaging
Real-time Eye Tracking and Imaging of the Eye in Diabetic Retinopathy Patients
Diabetic retinopathy (DR) is a leading cause of vision loss in working age Canadians. Current treatment consists of early detection and laser photocoagulation therapy for preventing progressive or severe vision loss.
- Trial name
- NCT05608265
- Testing
- OSNAT 800 IO
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- PulseMedica
Breast Cancer
Evaluation of the Bexa Breast Examination
Objective: The "Bexa Breast Exam," or "BBE," for the purposes of this study is defined as the use of a Bexa device in conjunction with a portable, focused ultrasound examination to identify and further evaluate abnormal breast…
- Trial name
- BBE (NCT06643767)
- Testing
- Bexa and focus ultrasound
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sure, Inc.
Healthy Volunteers, Breast Cancer
Study to Evaluate the Safety, Biodistribution, Radiation Dosimetry and Tumor Imaging Potential of [131I]-SGMIB Anti-HER2 VHH1 in Healthy Volunteers and Breast Cancer Patients
Primary purpose of the clinical study is to evaluate the safety, biodistribution and radiation dosimetry of [131I]-SGMIB Anti-HER2 VHH1 in healthy volunteers and patients with HER2+ breast cancer.
- Trial name
- CAM-VHH1 (NCT02683083)
- Testing
- [131I]-SGMIB Anti-HER2 VHH1
- Where
- Belgium
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Precirix
Facial Skin Aging, Facial Volume Loss
Comparing Facial Aging Between Identical Twins With 3D Imaging
Identical twins share the same genes, which makes them a powerful way to study how lifestyle and environment - rather than genetics - affect how faces age.
- Conditions
- Facial Skin Aging, Facial Volume Loss, Wrinkle Appearance
- Trial name
- NCT07760532
- Testing
- GLP-1 Receptor Agonists
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ponsky Facial Aesthetics And Plastic Surgery, Llc
Schizophrenia
The Effect of Ketamine on Attentiveness
The objective of this study is to develop an exploratory design for future Proof-of-Concept trials which reliably and accurately measure the central nervous system (CNS) effects of potentially new drugs that oppose the effects of…
- Trial name
- NCT01165294
- Testing
- ketamine
- Volunteers
- 24 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Alzheimer's Disease
Amyloid Imaging And Safety Study Of ACC-001 In Subjects With Early Alzheimer's Disease
This study in individuals with early Alzheimer's disease is designed to assess:(1) safety and tolerability (2) the capacity of ACC-001 and QS-21 adjuvant to reduce brain amyloid load as measured by positron emission tomography…
- Trial name
- NCT01227564
- Testing
- ACC-001 3 μg/ QS-21 50 μg, ACC-001 10 μg/ QS-21 50 μg
- Where
- 40 sites in United States
- Volunteers
- 63 people
- Sponsor
- Pfizer
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