Clinical trials: Imaging
Elastography, Shear Wave Elastography
HIBOC = Hepatic Imaging Biomarkers in Obese Children
The goal of this prospective, diagnostic observational study is to learn about how imaging based markers for components of liver disease appear in children with obesity.
- Conditions
- Elastography, Shear Wave Elastography, Shear Wave Dispersion, Attenuation Imaging
- Trial name
- NCT06463223
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Sahlgrenska University Hospital
Opioid-Related Disorders, Mobile Applications
Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder
The proposed clinical trial would evaluate the use of smartphone applications ("apps", which have well-established efficacy in reducing cigarette and alcohol use) to prevent relapse among patients receiving medication-assisted…
- Conditions
- Opioid-Related Disorders, Mobile Applications, Opiate Substitution Treatment, Magnetic Resonance Imaging
- Trial name
- NCT05336188
- Testing
- Smartphone
- Where
- United States
- Volunteers
- 336 people
- Sponsor
- University of Arkansas
Prostate Cancer, Molecular Imaging
Molecular Profiling of MRI-PSMA PET Discordance in Prostate Cancer
MRI and PSMA-PET are highly sensitive imaging tools for prostate cancer, yet they often detect different lesions. These discordant findings pose clinical uncertainty because their biological significance is unclear.
- Conditions
- Prostate Cancer, Molecular Imaging, Transcriptomics, RNA
- Trial name
- MP-PET-MRI (NCT07485257)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS San Raffaele
Multiparametric, Magnetic Resonance Imaging
Multiparametric MRI for Bladder Cancer: Validation of VI-RADS for the Detection of Muscle Invasive Bladder Cancer
This research aimed to determine how accurately multiparametric magnetic resonance imaging (MRI), when interpreted using the VI-RADS scoring system, can distinguish between invasive and non-invasive bladder cancer.
- Conditions
- Multiparametric, Magnetic Resonance Imaging, Validation, Vesical Imaging Reporting and Data System (VI-RADS)
- Trial name
- NCT07578233
- Testing
- Magnetic resonance imaging
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Chewing Problem, Cognitive Decline
Cognitive Changes and Neural Correlates After Rehabilitation of Masticatory Function in Elderly -an Intervention Study
Today in elderly tooth loss and loss of oral function is widespread, but it is an underexplored modifiable risk factor potentially contributing to the development of dementia.
- Conditions
- Chewing Problem, Cognitive Decline, Magnetic Resonance Imaging, Degenerative; Dementia
- Trial name
- NCT04458207
- Testing
- Oral prosthetic rehabilitation
- Where
- 2 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Folktandvården Stockholms län AB
Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET
FAPI PET/CT Imaging in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (FAPI-ARVC))
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease associated with fibrofatty myocardial replacement, ventricular arrhythmias, and an increased risk of sudden cardiac death.
- Conditions
- Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET, Cardiac Magnetic Resonance Imaging
- Trial name
- FAPI-ARVC (NCT07563660)
- Testing
- 68Ga-DOTA-SA-FAPI PET/CT
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Istanbul University - Cerrahpasa
Magnetic Resonance Imaging, Major Depression
Ketamine Alcohol (in Treatment-Resistant Depression)
A single subanesthetic dose infusion of the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine has rapid and robust antidepressant effects in patients with treatment-refractory major depressive disorder (TRD).
- Conditions
- Magnetic Resonance Imaging, Major Depression, Alcoholism
- Trial name
- NCT02122562
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mark Niciu
Procedural Anxiety, Procedural Pain
Stress Ball and Empathic Verbal-Tactile Interventions for Reducing Anxiety and Pain in Mammography and Breast Ultrasonography: A Randomized Trial
This prospective, randomized controlled trial aims to determine the effects of stress ball use and empathic verbal communication with therapeutic touch on anxiety and pain perception in women undergoing mammography and breast…
- Conditions
- Procedural Anxiety, Procedural Pain, Breast Imaging
- Trial name
- NCT07562828
- Testing
- Stress Ball, Empathic Verbal-Tactile Intervention
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Education, Medical, Ultrasound Imaging
Artificial Intelligence for Learning Point-of-Care Ultrasound
Point-of care-ultrasonography has the potential to transform healthcare delivery through its diagnostic and therapeutic utility.
- Trial name
- NCT05900440
- Testing
- Ultrasound with Artificial Inteligence Engabled, Ultrasound without Artificial Intelligence Enabled
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Stanford University
Imaging
JURA Study - Observational First-in-human Feasibility Study
Evaluate the functionality of the JURA System v. 1.0
- Trial name
- JURA (NCT07259759)
- Testing
- Visualization / Imaging
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Intuitive Surgical
Contrast Agent, Medical Imaging Data
ELUDYN: Assessment of Intra-individual Variability of Vascular Dynamics of Gadopiclenol Injection Parameters in Contrast-enhanced MRI
This study aims to understand how the volumes and speeds of intravenous injection of a recent type of contrast agent can be optimized in order to improve the information provided by medical images.
- Conditions
- Contrast Agent, Medical Imaging Data, MRI Image Enhancement
- Trial name
- ELUDYN (NCT07346131)
- Testing
- contrast agent, Gadolinium
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hôpital Fribourgeois
Gingival Vascularization, Oral Soft Tissue Wound Healing
Analysis of the Reliability and Validity of Laser Speckle Contrast Imaging
This study is designed to validate laser speckle contrast imaging (LSCI) as a non-invasive method for measuring superficial gingival blood perfusion.
- Conditions
- Gingival Vascularization, Oral Soft Tissue Wound Healing, Laser Speckle Contrast Imaging, Periodontal Wound Healing
- Trial name
- LSCI (NCT07527351)
- Testing
- Laser Speckle Contrast Imaging
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Treatment-naive Prostate Cancer, Suspected Prostate Cancer
Delayed PSMA PET/CT Imaging for Diagnosing Clinically Significant Prostate Cancer in Biopsy-Naïve Men With Suspected Prostate Cancer
Brief Summary This prospective, multicenter study evaluates whether delayed PSMA PET imaging improves diagnostic efficacy for detecting clinically significant prostate cancer (Gleason score ≥7) compared with standard imaging in…
- Conditions
- Treatment-naive Prostate Cancer, Suspected Prostate Cancer, Molecular Imaging
- Trial name
- DEPICT (NCT07531329)
- Testing
- [⁶⁸Ga]Ga-PSMA PET/CT with Delayed Pelvic PET-Only Acquisition
- Where
- 9 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Xijing Hospital
Cardiomyopathy, Dilated, Prognosis
Cardiac Magnetic Resonance-Clinical Prediction Model-Dilated Cardiomyopathy
Dilated cardiomyopathy (DCM) is a common and serious heart disease characterized by left ventricular enlargement and impaired pumping function, with adverse prognosis (including heart failure, arrhythmia, heart-related…
- Conditions
- Cardiomyopathy, Dilated, Prognosis, Magnetic Resonance Imaging, Cardiac, Death, Sudden, Cardiac
- Trial name
- MPS-CMR-DCM (NCT07527715)
- Testing
- left ventricular ejection fraction
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Digestive Diseases, Radiology
AI-Driven Multimodal Imaging Integration for Diagnosis and Prognostication of Digestive System Diseases
The goal of this observational, retrospective and prospective study is to develop a noninvasive disease assessment system by leveraging artificial intelligence (AI) to comprehensively analyze multi-modal imaging features…
- Conditions
- Digestive Diseases, Radiology, AI (Artificial Intelligence), Imaging
- Trial name
- NCT07087418
- Testing
- Virtual endoscopy model-assisted diagnosis
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Ketoses, Metabolic, Ketogenic Dieting
Effect of Nutritional Ketosis on Alcohol Metabolism
The research study is being conducted in health controls to better understand the effects of ketosis on brain functioning after 3 different, randomly assigned, 3-day dietary interventions and the acute effects of alcohol after…
- Conditions
- Ketoses, Metabolic, Ketogenic Dieting, Alcohol Intoxication, Magnetic Resonance Imaging
- Trial name
- KAM (NCT06065657)
- Testing
- Ketone Supplement, Control Diet, Ketogenic diet
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Femoral Artery Stenosis, Angioplasty
an Observational Study Evaluting the Effectiveness and Safety of DKutting LL Noval Scoring Balloon Angioplasty for Vessel Preparation Facilitated by IVUS on the Lower Limb Ischemia Patients With Calcified Lesions
This is a prospective, single-center, single-arm, observational study. It plans to enroll 58 patients with moderate to severely calcified lesions in the femoropopliteal or infrapopliteal arteries.
- Conditions
- Femoral Artery Stenosis, Angioplasty, Cutting Balloon Angioplasty, Calcifications, Vascular
- Trial name
- DkuLL CALVEP (NCT07397390)
- Testing
- DKutting LL scoring balloon angioplasty
- Where
- China
- Volunteers
- 58 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Heart Failure, Cardiac Imaging Techniques
MRI to Predict Rejection and Failure in Transplant and Cardiomyopathy Patients
Overall Research Strategy of this protocol is to refine and validate noninvasive CMR imaging sequences with invasive hemodynamic and pathology results to create a comprehensive, noninvasive, radiation-reduced regimen for…
- Conditions
- Heart Failure, Cardiac Imaging Techniques, Congenital Heart Defects
- Trial name
- NCT03822442
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Children's National Research Institute
Surgical Fitness, Imaging
Can Imaging be an Alternative to Exercise Testing as a Predictor of Surgical Fitness?
This study aims to explore an alternative method for assessing a participant's readiness for surgery, specifically for those undergoing surgery for gastric, oesophageal, or pancreatic cancer.
- Trial name
- RESPIRE (NCT06544187)
- Testing
- MRS scan, CPET
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Hospitals of North Midlands NHS Trust
Stroke, Magnetic Resonance Imaging
Intravoxel Incoherent Motion Prognostic Value in the Initial Evaluation of Patients With Acute Ischemic Strokes Using 3 Tesla Magnetic Resonance Imaging
Ischemic strokes are the first cause of handicap in adult people, the second cause of dementia and the third cause of death in France.
- Trial name
- IMPROVES (NCT03265860)
- Testing
- IntraVoxel Incoherent Motion sequence
- Where
- France
- Volunteers
- 274 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild