Clinical trials: Imaging
Chewing Problem, Cognitive Decline
Cognitive Changes and Neural Correlates After Rehabilitation of Masticatory Function in Elderly -an Intervention Study
Today in elderly tooth loss and loss of oral function is widespread, but it is an underexplored modifiable risk factor potentially contributing to the development of dementia.
- Conditions
- Chewing Problem, Cognitive Decline, Magnetic Resonance Imaging, Degenerative; Dementia
- Trial name
- NCT04458207
- Testing
- Oral prosthetic rehabilitation
- Where
- 2 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Folktandvården Stockholms län AB
Magnetic Resonance Imaging Contrast Media Adverse Reaction, Sedation Complication
Non-operating Room Anesthesia Experiences in Pediatric Magnetic Resonance Imaging Cases
In recent years, out patient anesthesia applications have been increasing for diagnostic and interventional procedures for pediatric patients.
- Trial name
- NCT05423821
- Testing
- Anesthesia efficacy in patients undergoing MRI
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Yunus Emre
Breast Cancer
High Risk Screening Breast MR Using a Rapid Imaging Exam
This study is being done to find out if breast cancer detection will be improved using a short MRI (magnetic resonance imaging) scan, in addition to mammography, in patients who are at an increased risk of developing breast…
- Trial name
- NCT00588614
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hernia, Recurrence
Magnetic Resonance Imaging of Mesh Position After Ventral Hernia Repair
Purpose of the study is the visualization of the mesh and the determination of the mesh surface observed by MRI at 3 weeks and 13 months after ventral hernia repair with mesh visible IPOM (Dynamesh®).
- Trial name
- NCT02177214
- Testing
- MRI scan
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Abdominal Aortic Aneurysm (AAA), No Abdominal Aortic Aneurysm (Non-AAA)
NIH CCR2 AAA Study
Abdominal aortic aneurysm (AAA) is a degenerative vascular disease, which is typically asymptomatic until rupture, resulting in high mortality.
- Trial name
- NCT04586452
- Testing
- AAA Group (Aim 3A), Non-AAA Group, Ex Vivo Human AAA Specimens (Aim 2A)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Urethral Internal Sphincter Morphology, Benign Prostatic Hyperplasia
MRI-DTI Assessment of Urethral Internal Sphincter Ring and Prostate Base Morphology
This is a single-center, observational imaging study designed to evaluate the in vivo morphology of the male urethral internal sphincter ring using magnetic resonance diffusion tensor imaging (MRI-DTI) fiber tracking and to…
- Conditions
- Urethral Internal Sphincter Morphology, Benign Prostatic Hyperplasia, Prostate Cancer
- Trial name
- NCT07694752
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Jiangsu Taizhou People's Hospital
Myocardial Ischemia
Evaluation of Myocardial Ischemia Using Standard Single Photon Emission Computed Tomography (SPECT) With Regadenoson and Simultaneous Cardiac Echocardiography
This study is for people who have a SPECT scan (nuclear imaging of the blood flow to the heart muscle) ordered by their medical doctors.
- Trial name
- Lexi-Echo (NCT01150578)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- Aiden Abidov
Angina, Heart Disease
Impact of Ranolazine on Myocardial Ischemia Detected by High-Field 3T Cardiovascular Magnetic Resonance (CMR) Imaging and P-31 Spectroscopy
Evaluation of use of ranolazine in patients with stable heart pain with cardiac magnetic resonance imaging (CMRI) and phosphorous-31 magnetic resonance spectroscopy (31P MRS).
- Trial name
- NCT01804543
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Westside Medical Associates of Los Angeles
Obesity (BMI>30)
MRI Assessment of Body Composition in Bariatric Surgery
The goal of this observational study is to evaluate changes in adipose tissue and skeletal muscle distribution using magnetic resonance imaging (MRI) in adults with obesity undergoing bariatric surgery.
- Trial name
- COMPOSE (NCT07711925)
- Testing
- MRI
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Parkinson's Disease
fMRI-guided Transcranial Magnetic Stimulation Treatment for Parkinson's Disease
The goal of this clinical trial is to compare the efficacy of targeting the newly discovered SCAN versus traditional effector-specific networks in M1 using multimodal imaging and rTMS in patients with Parkinson's disease.
- Trial name
- NCT06734676
- Testing
- Intermittent theta burst stimulation (iTBS)
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Changping Laboratory
Intracerebral Haemorrhage
Ischaemic Lesions in Acute Intracerebral Haemorrhage
The aim of this observational study is to determine how and why inadequate brain blood flow occurs after bleeding in patients with intracerebral haemorrhage (ICH).
- Trial name
- CHALLENGE-ICH (NCT06410274)
- Testing
- Transcranial Doppler ultrasonography (TCD)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Leicester
Dry Eye Syndrome, Tear Film Insufficiency
Corneal Tear Film Imaging of the Cornea Before and After Restasis Therapy
Dry Eye Syndrome (DES) is a disease affects the production and stability of the tear film, leading to vision disturbances and a major decrease in quality of life.
- Trial name
- NCT03403023
- Testing
- Tear Film Imager, Restasis
- Volunteers
- 40 people
- Sponsor
- Meir Medical Center
CAR T-Cell Therapy
Neuroimaging and Biomarkers of Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy
The goal of this study is to understand why some people receiving chimeric antigen receptor (CAR) T-cell therapy for cancer experience neurotoxicity.
- Trial name
- NCT07075523
- Testing
- Brain magnetic resonance imaging, neurocognitive assessments, quality of life questionnaire, biomarkers
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of California, San Diego
Glioblastoma Multiforme of Brain
MRSI to Predict Response to RT/TMZ ± Belinostat in GBM
In the first phase of this study (Cohort 1), the investigators will determine the feasibility of adding MRSI to the evaluation of newly-diagnosed GBM patients treated with standard RT/TMZ and determine whether magnetic resonance…
- Trial name
- NCT02137759
- Testing
- Standard Radiation Therapy, Standard Temozolomide, Belinostat
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Emory University
Magnetic Resonance Imaging
Quantitative T1rho Magnetic Resonance Imaging in Healthy Subjects
T1rho imaging is a new MRI technique that has strong potential in neuroimaging. This technique does not require exogenous contrast agents and has high spatial resolution.
- Trial name
- NCT04993196
- Testing
- T1rho imaging
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Asthma
Assessment of Bronchial Thickness Using MRI in Asthma
Bronchial remodeling is a major pathological feature of asthma. Non-invasive assessment of this bronchial remodeling is a crucial issue for asthma patients' follow-up.
- Trial name
- ASTHMAGRI (NCT03089346)
- Testing
- Magnetic Resonance Imaging (MRI) with Ultrashort Echo Time (UTE), Computed tomography (CT)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bordeaux
Coronary Artery Disease
VIBE-assisted DEB Registry
VIBER aims at assessing angiographic outcome of drug-eluting balloon angioplasty assisted by the Vascular Imaging Balloon Catheter (VIBE, Volcano, San Diego, CA) device, which integrates a predilation catheter with electronic…
- Trial name
- VIBER (NCT01411462)
- Testing
- VIBE + drug-eluting balloon
- Where
- Italy
- Sponsor
- Ospedale Santa Maria Goretti
Utilization, Laboratory, Hospital
Effect of Norms on Laboratory and Imaging Testing (ENLITen)
Studies suggest that some laboratory tests ordered for hospitalized patients are duplicative or have limited value. This study will evaluate a normative feedback intervention to reduce overuse of laboratory tests for hospitalized…
- Trial name
- ENLITen (NCT02330289)
- Testing
- Normative report card
- Volunteers
- 154 people
- Sponsor
- University of Pennsylvania
ST-Elevation Myocardial Infarction (STEMI), Heart Failure With Preserved Ejection Fraction (HFpEF)
Platelet Derived Growth Factor Receptor ß (PDGFRß) Imaging in Cardiac Fibrosis
An observational, cross-sectional, longitudinal, microdosing Position Emission Tomography (PET) imaging study to investigate platelet derived growth factor receptor beta (PDGFRß) expression in the heart of patients with high or…
- Trial name
- PARIS (NCT06956560)
- Testing
- PET/MRI or separate PET/CT and MRI
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Cancer, Metabolic Disease
An Observational Study On TheAccuracy Of Whole-Body Magnetic Resonance Imaging (Wb-Mri) ScreeningTo Predict Clinically Significant Diagnoses In General Population Subjects Interested In Proactive And Advanced General Preventive Healthcare.
This is a prospective, single-arm, observational study capturing data from whole-body magnetic resonance imagining (WB-MRI) from up to 100,000 male and female subjects 18 years of age or older recruited at multiple clinical sites…
- Conditions
- Cancer, Metabolic Disease, Aneurysm, Neurologic Disorder
- Trial name
- Hercules (NCT06212479)
- Testing
- MRI Scan
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Hercules