Clinical trials: Imaging Guided
Ultrasound Imaging of Anatomical Structures
Clinical Performance Study: Evaluate Scanning & Interpretation Performance With & Without ScanNav Anatomy PNB
This is a single-centre, randomised, interventional prospective cohort study to be undertaken at offices of Intelligent Ultrasound Limited in Cardiff, United Kingdom.
- Trial name
- PNB (NCT05156099)
- Testing
- Ultrasound Scanning, Ultrasound Scanning - 2 months later
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- IntelligentUltrasound Limited
Breast Cancer
MRg-NIRS Imaging System Breast Cancer Trial
This trial is a study of 20 women with breast cancer to evaluate the addition of MR-guided (MRg) near-infrared spectroscopy (NIRS) with and without contrast, as part of a program to improve clinical management of women receiving…
- Trial name
- MRg-NIRS (NCT06400563)
- Testing
- MRg-NIRS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Keith D. Paulsen
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
Real-time Margin Assessment in Head and Neck Cancer
To investigate if the combination of fresh frozen sectioning based on cetuximab-800CW can enhance tumor-positive margin detection intra-operatively.
- Trial name
- LIGHTNING (NCT05499065)
- Testing
- Fluorescence guided detection of tumor positive margins, Cetuximab-IRDye800
- Where
- Netherlands
- Volunteers
- 23 people
- Sponsor
- University Medical Center Groningen
Non-hepatobiliary Indications
EUS-Guided ATI and SWE in Individuals With Normal FibroScan
The goal of this observational study is to establish preliminary reference values for Endoscopic Ultrasound (EUS)-guided Attenuation Imaging (ATI) and Shear Wave Elastography (SWE) in adults undergoing diagnostic EUS for…
- Trial name
- EUS ATI&SWE (NCT07714941)
- Testing
- Endoscopic Ultrasound (EUS), EUS-guided Attenuation Imaging (ATI), EUS-Guided Shear Wave Elastography (SWE)
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Asian Institute of Gastroenterology, India
Prostate Cancer, Prostate Cancer (Adenocarcinoma)
A Single-Arm, Blinded, Fluorescent PSMA Histopathology Trial of AS1986NS
A Single-Arm, blinded, fluorescent PSMA histopathology trial of AS1986NS
- Conditions
- Prostate Cancer, Prostate Cancer (Adenocarcinoma), Fluorescence Imaging
- Trial name
- LUMA-PSMA (NCT06906471)
- Testing
- AS1986NS
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Antelope Surgical Solutions, Inc
Suspected Prostate Cancer
MRI Guided Prostate Biopsy
This study aims to assess the feasibility of magnetic resonance (MR) guided prostate biopsy using a needle holder frame. This frame is used to help position the needle used for the biopsy.
- Trial name
- NCT06302595
- Testing
- MRI-guided prostate biopsy using the needle holder frame.
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Brigham and Women's Hospital
Peripheral Artery Disease, Critical Limb Ischemia
Imaging-Guided Vessel Sizing in the Tibial Arteries
This study aims to investigate the utilization of intravascular imaging in treatment of tibial vessels in peripheral artery disease and critical limb ischemia (CLI).
- Trial name
- iVEST (NCT04748965)
- Testing
- Digital Subtraction Angiography
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Lung Cancer (Including Metastatic Cancer), Radiation Pneumonitis
Functional Lung Avoidance Radiotherapy Guided by 4DCT Pulmonary Ventilation Function Imaging: A Prospective Single-arm Clinical Study
This prospective, single-center, single-arm study will evaluate the feasibility and safety of 4DCT ventilation functional imaging-guided functional lung avoidance radiotherapy (FLAR) in patients with lung malignancies receiving…
- Conditions
- Lung Cancer (Including Metastatic Cancer), Radiation Pneumonitis, Radiation-induced Lung Injury
- Trial name
- 4DCT-FLAR (NCT07339644)
- Testing
- 4DCT Ventilation Imaging-Guided Functional Lung Avoidance Radiotherapy (FLAR)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
HNSCC,Larynx, Pharynx and Oral Cavity, Squamous Cell Carcinoma
Study Evaluating the Safety and Feasibility of Panitumumab-IRDye800 and [18F]NOTA-ABY-030 for Targeted Dual-Modality Imaging (TDMI) in Head and Neck Squamous Cell Carcinoma
The goal of this clinical trial is to learn whether using two imaging agents-Panitumumab-IRDye800 (Pan800) and[18F]NOTA-ABY-030-is safe and feasible for helping surgeons identify tumors and cancer-containing lymph nodes during…
- Conditions
- HNSCC,Larynx, Pharynx and Oral Cavity, Squamous Cell Carcinoma, Head and Neck Cancer, Head and Neck Surgery
- Trial name
- NCT07741643
- Testing
- Panitumumab-IRDye800, [18F]NOTA-ABY-030
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Hallucinations, Schizophrenia
Multimodal MRI-guided rTMS to Treat Refractory Hallucinations
The efficacy of neuro-navigated rTMS for patients with schizophrenia suffering from drug-resistant multisensory hallucinations will be tested by the implementation of a double-blind randomized controlled trial (RCT) This study…
- Conditions
- Hallucinations, Schizophrenia, Perceptual Disorders
- Trial name
- MULTIMODHAL (NCT01373866)
- Testing
- MagPro X100 repetitive Transcranial Magnetic Stimulation
- Where
- 2 sites in France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Lille
Gliomas, Malignant, Metastases to Brain
Intraoperative Sonographically Versus Fluorescence-guided Resection of Contrast-enhancing Gliomas and Brain Metastases
Objective of the study is to determine whether intraoperative ultrasound guided resection of gliomas with contrast enhancement in magnetic resonance imaging and brain metastases can achieve as high rate of gross total resection…
- Trial name
- SONOFLUO (NCT05475522)
- Testing
- Ultrasound guided brain tumor resection, 5-aminolevulinic acid fluorescence-guided brain tumor resection
- Where
- Russia
- Volunteers
- 134 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Lung Cancer
Piloting a Virtual Navigation (VN) System for Bronchoscopic Lung Nodule Sampling
The overall goal is to evaluate the role of a Virtual Navigation (VN) system (the Virtual Navigator) in the bronchoscopic evaluation and tissue sampling of lung cancer and other chest lesions at the Penn State Hershey Medical…
- Trial name
- NCT05599321
- Testing
- Virtual Navigation System
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Penn State University
Cancer, Bone Metastases
Magnetic Resonance Guided High Intensity Focused Ultrasound (MRgHIFU) for Pain Palliation of Bone Metastases
The primary objective of this study is to determine whether intra- and post-procedural MR changes are indicative of reduction in pain symptom scores.
- Trial name
- HIFU-Bone (NCT03479151)
- Testing
- Magnetic Resonance Image-guided High Intensity Focused Ultrasound (MR-HIFU)
- Where
- United Kingdom
- Sponsor
- Institute of Cancer Research, United Kingdom
Prostate Cancer
Targeted Cryoablation of Prostate Cancer Lesions: An Investigator-initiated Trial
This clinical trial is to provide a minimally invasive treatment option in which the targeted prostate cancer tissue is killed by cryoablation at extremely low temperatures only in the specific area of cancer "that should be…
- Trial name
- PROCRY (NCT05500846)
- Testing
- The Visual Ice Cryoablation System
- Where
- 2 sites in Japan
- Volunteers
- 51 people
- Sponsor
- Osamu Ukimura
Malignancy, Infection
Augmented Reality Headset as Adjunct Display Monitor in AMIGO
The investigators' overarching goal is to investigate whether use of an augmented reality display system (utilized in addition to, not as a replacement to, conventional CT and MRI displays currently available in the procedure…
- Conditions
- Malignancy, Infection, Pain
- Trial name
- NCT03328416
- Testing
- Augmented Reality
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Edentulous Jaw
Horizontal Augmentation With Deproteinized Bovine Bone Mineral Alone or in Combination With Particulate Autogenous Bone
Background: Placement of oral implants is frequently compromised due to atrophy of the alveolar process. Lateral ridge augmentation with an autogenous bone block is frequently necessary to increase the width of the alveolar…
- Trial name
- NCT04755166
- Testing
- Lateral ridge augmentation
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- NU-Hospital Organization, Sweden
Coronary Artery Disease, Angina Pectoris
PREcise Percutaneous Coronary Intervention for Stent OptimizatION in Treatment of COMPLEX Lesion (PRECISION-COMPLEX)
The aim of the study is to compare post-interventional fractional flow reserve (FFR) value between optical coherence tomography(OCT)-guided and angiography-guided strategy for treatment of complex coronary lesion.
- Trial name
- NCT05493904
- Testing
- OCT-guided PCI, Angiography-guided PCI, Drug-eluting stent
- Where
- 4 sites in South Korea
- Volunteers
- 320 people
- Sponsor
- Chonnam National University Hospital
Glioma
IRDye800CW-BBN PET-NIRF Imaging Guiding Surgery in Patients With Lower Grade Glioma
This is an open-label positron emission tomography/near infrared (PET/NIRF) study to investigate the imaging navigation performance and evaluation efficacy of dual modality imaging probe 68Ga-BBN-IRDye800CW in patients with lower…
- Trial name
- NCT03407781
- Testing
- 68Ga-BBN-IRDye800CW
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Deling Li
Brain Neoplasms, Brain Tumor
MR Guided Laser Interstitial Thermal Therapy for the "Minimal Invasive" Treatment of Brain Metastasis and Primary Brain Tumors
The purpose of this study is to determine if the stereotactic, MR guided, laser interstitial thermal therapy treatment technique can be safety and efficiently used for human brain metastasis and primary brain tumors.
- Conditions
- Brain Neoplasms, Brain Tumor, Brain Cancer, Recurrent Brain Tumor
- Trial name
- NCT00392119
- Testing
- MR-guided Laser Interstitial Thermal Therapy System
- Where
- France
- Volunteers
- 18 people
- Sponsor
- BioTex, Inc.
Cervix Cancer
Prediction of Clinical Response and Outcome in Uterine Cervix Cancer
Observational study based on the routine clinical treatment and diagnostic course, to correlate imaging features with outcome objectives.
- Trial name
- NCT01764217
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Maastricht Radiation Oncology