Clinical trials: Imaging Guided
Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy
Tractography-Guided Nerve-Sparing in Prostate Cancer
Radical prostatectomy (RP) is an effective treatment leading to a high rate of oncological control. However, despite advances in robot-assisted RP, the genito-urinary function, especially erectile function and urinary continence…
- Conditions
- Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy, Urinary Incontinence Following Surgical Procedure
- Trial name
- PRO-TRACT (NCT07847385)
- Testing
- Prostate Tractography for Nerve-Sparing
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Massimo Valerio
Degenerative Knee Disorders, Knee Osteoarthritis
Artificial Intelligence-Assisted Advanced Analysis of Knee Imaging and Outcome Prediction
This study aims to develop and validate an artificial intelligence (AI)-assisted platform for musculoskeletal knee ultrasonography and to establish an interpretable prediction model for clinical outcomes following…
- Conditions
- Degenerative Knee Disorders, Knee Osteoarthritis, Musculoskeletal Ultrasonography, Artificial Intelligence
- Trial name
- AI; R-CNN (NCT07721116)
- Testing
- artificial intelligence-assisted advanced analysis
- Where
- Taiwan
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Ventricular Tachycardia (VT), Ischemic Cardiomyopathy
MRI-guided Ventricular Tachycardia Ablation in Patients With Structural Heart Disease
Ventricular tachycardia (VT) is a life-threatening heart rhythm disorder that frequently occurs in patients with structural heart disease, such as ischemic or non-ischemic cardiomyopathy.
- Conditions
- Ventricular Tachycardia (VT), Ischemic Cardiomyopathy, Non-ischemic Cardiomyopathy
- Trial name
- MAGNET-VT (NCT07896980)
- Testing
- LGE-MRI-integrated EAM-guided catheter ablation, Conventional EAM-guided catheter ablation
- Where
- China
- Volunteers
- 526 people
- Sponsor
- China National Center for Cardiovascular Diseases
ST Segment Elevation Myocardial Infarction (STEMI)
Evaluating the Safety and Efficacy of Drug-Coated Autoperfusion Balloons Versus Conventional Drug-Coated Balloons Guided by IVUS-OCT Multimodal Imaging for Treating Acute Myocardial Infarction: OPERA-AMI Study
Trial Goals: 1. Evaluation of Mid- to Long-Term Safety and Effectiveness of Drug-Coated Autoperfusion Balloon Dilatation Catheter (DCAB) versus Conventional Drug coated balloon (DCB) in Patients with ST Segment Elevation…
- Trial name
- NCT06794801
- Testing
- Drug Coated Autoperfusion Balloon Dilatation Catheter（DCAB）, Conventional Drug coated balloon (DCB)
- Where
- China
- Volunteers
- 134 people
- Sponsor
- LanZhou University
Metastatic Colorectal Cancer
Image Guided Treatment Optimization With Cetuximab for Patients With Metastatic Colorectal Cancer
In this study the investigators will evaluate the uptake of 89Zirconium labeled cetuximab in extra-hepatic colorectal metastases. The investigators hypothesize that uptake of 89Zr-cetuximab is required for response to cetuximab.
- Trial name
- IMPACT-CRC (NCT02117466)
- Testing
- Dose escalation cetuximab, Standard dose cetuximab
- Where
- 3 sites in Netherlands
- Volunteers
- 85 people
- Sponsor
- Amsterdam UMC, location VUmc
Image, Body
Augmenting Ultrasound Imaging in Order to Replace Fluoroscopy in Image Guided Pain Procedures
Utilizing existing data from CT/MRI images of patients, the investigators wish to develop an algorithm for augmenting the image obtained by ultrasound. In order to improved injection by ultrasound guidance
- Trial name
- NCT04528875
- Testing
- Ultrasound imaging
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Nonvalvular Atrial Fibrillation
TEE-Guided Versus CCTA-Guided Preprocedural Imaging for Left Atrial Appendage Closure
This prospective, open-label, multicenter randomized controlled trial will compare two preprocedural imaging assessment strategies in adults with nonvalvular atrial fibrillation who are scheduled to undergo percutaneous left…
- Trial name
- PEARL-LAAC (NCT07815119)
- Testing
- Transesophageal Echocardiography-Guided Preprocedural Assessment, Cardiac Computed Tomography Angiography-Guided Preprocedural Assessment
- Where
- China
- Volunteers
- 590 people
- Sponsor
- Shanghai Zhongshan Hospital
Brain Neoplasms, Eloquent Area Brain Tumors
CONNEctome-guided Navigation for Eloquent-area Tumor Surgery Trial
This study is designed for patients with brain tumors located in eloquent brain areas involved in language, motor, or major functional brain networks.
- Trial name
- CONNECT Trail (NCT07657403)
- Testing
- Connectome-Guided Navigation-Assisted Microsurgical Resection, Conventional DTI Tractography-Guided Tumor Resection
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Generalized Anxiety Disorder
Repetitive Magnetic Transcranial Stimulation (rTMS) in the Treatment of Generalized Anxiety Disorder (GAD)
Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive method that holds promise for treating several psychiatric disorders. Yet the most effective location and parameters for treatment need more exploration.
- Trial name
- NCT00662584
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Los Angeles
Adenocarcinoma
PRIMER: Development of Daily Online Magnetic Resonance Imaging for Magnetic Resonance Image Guided Radiotherapy
In radiotherapy high-tech scans with x-rays (CT scans) are taken before and during treatment to locate the tumour and ensure the radiation is hitting the target.
- Trial name
- NCT02973828
- Testing
- Imaging
- Where
- United Kingdom
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Institute of Cancer Research, United Kingdom
Atrial Fibrillation
Risk of Asymptomatic Cerebral Embolism During AF Ablation With AI-HPSD Strategy Versus Standard Settings
The purpose of this prospective randomized controlled study is to evaluate the risk of asymptomatic cerebral embolism during catheter ablation of atrial fibrillation (AF) with AI-HPSD strategy versus standard radiofrequency…
- Trial name
- NCT04408716
- Testing
- Ablation Index Guided High-Power Short-Duration Strategy, Standard Radiofrequency Ablation Technique
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Malignant Brain Tumors, Glioma
Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG
Participants in this research study are people who are likely to have, or have been diagnosed with a brain tumor, for which surgical removal (or "resection") is the standard of care treatment.
- Trial name
- NCT07438860
- Testing
- SBK2-ICG, Craniotomy (Standard of Care)
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Tiffany Hodges
Prostate Cancer
Study of MR-based IGRT for Prostate Cancer
MR (Magnetic Resonance Imaging) - based IGRT (image-guided radiotherapy) for patients with prostate carcinoma.
- Trial name
- M-basePro (NCT02724670)
- Testing
- IGRT
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- University Hospital Tuebingen
Cervical Cancer
Gynaecologic Organ Segmentation and Motion Tracking Using Ultrasound
This study will establish the feasibility and accuracy of localising and outlining the uterus on ultrasound images using both healthy volunteer and cervical patient cohorts.
- Trial name
- GENIUS (NCT02503917)
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Renal Tumors
Imaging-Guided Classification for Endophytic Renal Tumors: PN Strategies & Outcomes
Study Title: Imaging-Guided Classification \& Surgical Outcomes in Endophytic Renal Tumors Study Goal: This observational study investigates whether an imaging-guided classification system improves partial nephrectomy (PN)…
- Trial name
- NCT06954571
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Tianjin Medical University Second Hospital
Coronary Artery Disease, Coronary Stenosis
QFR-Guided Virtual Stenting for Preprocedural Physiological Optimization of Percutaneous Coronary Intervention: A Randomized Controlled Trial
Coronary angiography-guided percutaneous coronary intervention (PCI) remains the standard treatment strategy for patients with coronary artery disease; however, suboptimal post-PCI physiological outcomes remain common and are…
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Ischemic Heart Disease
- Trial name
- FAVOR-Virtual (NCT07635407)
- Testing
- Virtual Stenting-Guided PCI Optimization, Standard Angiography-Guided PCI
- Where
- China
- Volunteers
- 1,472 people
- Sponsor
- China National Center for Cardiovascular Diseases
Bone Metastases, Bone Neoplasm
MR Imaging- Guided High Intensity Focused Ultrasound (HIFU) Therapy of Bone Metastases
Bone metastasis give rise to major complications that lead to significant morbidity and impairment of life quality. The most common primary for bone metastasis is prostate, lung and breast carcinoma.
- Conditions
- Bone Metastases, Bone Neoplasm, Bone Cancer, Bone Lesion
- Trial name
- NCT03106675
- Testing
- Thermal ablation of bone metastasis with MR-HIFU device Philips Sonalleve coupled with Philips Ingenia 3.0T, Varian Truebeam Radiotherapy System
- Volunteers
- 30 people
- Sponsor
- Turku University Hospital
Cardiac Disease
Ultrasound Guided Internal Jugular Vein Cannulation Using Biplanar Imaging: A Pilot Study
Central Venous access by real-time ultrasound guidance is considered as gold standard and a recommended clinical practice. Internal jugular vein cannulation is one of the central venous access commonly used for major cardiac…
- Trial name
- NCT04432844
- Testing
- Biplanar Ultrasound guided Internal Jugular Vein Cannulation
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Rectal Cancer, Sigmoid Colon Cancer
Indocyanine Green Lymphatic Mapping in Minimally Invasive Sigmoid and Rectal Cancer Surgery
This prospective, single-center, non-randomized study with a historical control group evaluated the clinical utility of indocyanine green-guided lymphatic mapping (ICG-LM) during minimally invasive surgery for sigmoid colon and…
- Trial name
- NCT07916532
- Testing
- Intraoperative ICG-Guided Lymphatic Mapping
- Where
- Poland
- Volunteers
- 29 people
- Sponsor
- Jagiellonian University
Shoulder Pain
High Resolution Ultrasound in Evaluation of Shoulder Pain Guided by MRI
To asses causes of shoulder pain by Ultrasound in guide of MRI diagnosis to help Ultrasound to be used alone in the future
- Trial name
- NCT03891992
- Volunteers
- 50 people
- Sponsor
- Assiut University