Clinical trials: Immediate Effect
Contracture of Elbow Joint
Immediate Effects of Superficial Heat Associated With Elongation in the Posttraumatic Elbow Contracture
The elbow contracture is a secondary injury that can occur after direct trauma, causing the patient to have limitations in their range of motion.
- Trial name
- NCT03179098
- Testing
- Modified Weeks protocol, CIVM, GC- Sustained Stretching
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Trauma, Inflammation
Effect of C1-esterase Inhibitor on Systemic Inflammation in Trauma Patients With a Femur or Pelvic Fracture
Trauma and major operation are associated with an excessive inflammation reaction due to tissue injury. This overwhelming immune response is considered to be a major risk factor in the pathogenesis of late inflammatory…
- Conditions
- Trauma, Inflammation, Sepsis, Multiple Organ Dysfunction Syndrome
- Trial name
- CAESAR (NCT01275976)
- Testing
- C1-esterase inhibitor, Saline 0.9%
- Where
- Netherlands
- Volunteers
- 11 people
- Sponsor
- UMC Utrecht
Rhinitis,Allergic
Effects of Broccoli Sprout Extract on Allergy Rhinitis
Allergic rhinitis is a common illness suffered among US Veterans. There are medications that help relieve allergy symptoms, including nasal steroid sprays and antihistamines.
- Trial name
- NCT02885025
- Testing
- Broccoli Sprout Extract, fluticasone nasal, normal saline nasal spray
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Seasonal Allergic Rhinitis
Comparison of the Effect of Montelukast and Cetirizine on Allergic Inflammation in Children With Allergic Rhinitis
The aim of this study is to compare the effect of montelukast and cetirizine on allergic inflammation measured by exhaled nitric oxide concentration in children with seasonal allergic rhinitis.
- Trial name
- NCT00488176
- Testing
- montelukast, cetirizine, montelukast and cetirizine
- Where
- Poland
- Volunteers
- 116 people
- Sponsor
- Medical University of Lodz
Growth & Development, Obesity
Effects of Infant Egg Consumption on Child Health and Cognition Development
The objective of this study is to examine how infant egg consumption (age of introduction and frequency of intake) influences physical growth, obesity, cardio-metabolic health, risk of food allergy, and cognition development in…
- Conditions
- Growth & Development, Obesity, Cardiovascular Risk Factor, Metabolic Syndrome
- Trial name
- NCT04345185
- Testing
- Infant egg consumption (i.e., age of introduction and frequency of intake)
- Where
- United States
- Volunteers
- 5,374 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Asthma
The Effect of Odors on Asthma Symptoms
An extended replication of Jaen \& Dalton (2014), the investigators aim to investigate the role of odors and associated trigger beliefs on symptom perception and airway inflammation in individuals with asthma
- Trial name
- NCT02624362
- Testing
- Therapeutic Suggestion, Asthmogenic Suggestion, Phenylethyl Alcohol odor
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Asthma
Ultra-long Acting Bronchodilator Therapy in Smoking Asthmatics
Single centre, open-label, random order, cross-over trial, recruited over a period of approximately 2 years. Sufficient participants enrolled to complete 16 adults. Withdrawn subjects may be replaced.
- Trial name
- MAN05 (NCT02682862)
- Testing
- olodaterol hydrochloride 2.5mcg, tiotropium bromide 2.5mcg, olodaterol 2.5 mcg
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Dundee
Asthma
A Study of the Bronchodilator Effect of Formoterol Fumarate Used in Combination With Mometasone Furoate Metered Dose Inhaler in Children With Persistent Asthma (P06476 AM2)
A study to compare the bronchodilatory effect of a single dose of Mometasone Furoate/Formoterol Fumarate (MF/F) pressurized metered dose inhaler (MDI) delivered with and without an AeroChamber Plus® with Flow-Vu® Anti-Static…
- Trial name
- NCT01258803
- Testing
- Formoterol Fumarate DPI, Mometasone Furoate/Formoterol Fumarate MDI (ex-actuator) without spacer, Mometasone Furoate/Formoterol Fumarate MDI (ex-actuator) with spacer
- Volunteers
- 92 people
- Sponsor
- Organon and Co
Asthma
A Pharmacokinetic/Pharmacodynamic Inhaler Comparison Study in Healthy Volunteers
A 2-group healthy volunteer study to compare a breath actuated inhaler (BAI) and a pressurised metered dose inhaler (pMDI) with and without spacer.
- Trial name
- NCT02403713
- Testing
- Fluticasone/formoterol BAI, Formoterol, Fluticasone/formoterol PMDI without spacer
- Where
- United Kingdom
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Mundipharma Research Limited
Health Young Individuals
The Immediate Effect of Manual Therapy Application on Respiratory Functions in Healthy Young Individuals
Manual therapy techniques targeting the thoracic region are commonly used in clinical practice. It has been suggested that manual therapy interventions directed at the spine can increase mobility of the spine and chest wall…
- Trial name
- NCT05934240
- Testing
- Manual therapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Tension-Type Headache
Immediate Effects of Suboccipital Muscle Release Combined With Sustained Natural Apophyseal Glides in Patients With Chronic Tension Type Headache
Headache disorder characterized by recurrent headache are among the most common disoredrs of the nervous system. Tension type headache is widely recognized kind of headache that affects 80% of the individuals.
- Trial name
- NCT05883813
- Testing
- sustained natural apophyseal glides (SNAGS), suboccipital muscle release, Supplemental therapy
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Foundation University Islamabad
Chronic Urticaria, Anxiety
Positive Psychotherapy-Based Counseling (PPT)
Chronic urticaria is a condition that impairs the patient's quality of life, interferes with routine daily activities, and is often associated with anxiety.
- Trial name
- NCT05513079
- Testing
- Positive Psychotherapy Based Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- TC Erciyes University
Asthma
Bronchodilatation Effects of a Small Volume Spacer Used With a Metered-Dose Inhaler
The purpose of the present study is to determine whether use of a small volume spacer is associated with better bronchodilatation in an unselected population of patients with documented reversible airflow limitations.
- Trial name
- MDI (NCT00465413)
- Testing
- Small volume spacer and/or Rinsing the mouth with water
- Where
- 2 sites in Taiwan
- Volunteers
- 300 people
- Sponsor
- Mackay Memorial Hospital
Allergic Asthma, Allergic Rhinitis
Effect of Montelukast on Basophils, In-vitro
Subjects with either allergic asthma or allergic rhinitis will be recruited to obtain blood. This blood will be used to be stimulated with to whatever the patient allergic.
- Trial name
- NCT00710450
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Creighton University
Allergy to House Dust Mite, Allergic Asthma
Effects of Tregalizumab on Allergen-induced Airway Responses and Airway Inflammation in Asthmatic Patients
The study will be conducted as a randomized, double-blind, placebo-controlled, single-center study in adult patients with mild controlled allergic asthma and house dust mite allergy.
- Trial name
- Tregulaire (NCT04673591)
- Testing
- Tregalizumab
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- T-Balance Therapeutics GmbH
Allergic Asthma
Effect of Xolair on Airway Hyperresponsiveness
The purpose of this study is to determine if Xolair can reduce the abnormal increase in limitation to airflow in patients with asthma in a relatively short time period.
- Trial name
- NCT00208234
- Testing
- Omalizumab
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Creighton University
Eosinophilic Esophagitis
Allergy Immunotherapy in the Management of Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is a disease that has increased in incidence over the past decade that affects males predominantly, and in adults, is characterized by heartburn, dysphagia, strictures and food impactions.
- Trial name
- AIMEE (NCT01685034)
- Testing
- Allergy immunotherapy ("allergy shots")
- Sponsor
- United States Naval Medical Center, San Diego
Asthma
EFFORT Asthma: Effects of Diet and Exercise in Asthma
This project aims to study the effects of lifestyle changes on asthma and systemic inflammation in a randomized clinical trial of diet and exercise.
- Trial name
- EFFORT (NCT02355964)
- Testing
- Exercise, Diet
- Where
- Denmark
- Volunteers
- 149 people
- Sponsor
- University of Copenhagen
Asthma
Effect of Vitamin D as add-on Therapy for Vitamin D Insufficient Patients With Severe Asthma
The purpose of the EVITA trial is to compare the effects of vitamin D therapy with placebo on reducing the dose of inhaled or oral corticosteroids in patients with severe asthma and vitamin D insufficiency.
- Trial name
- EVITA (NCT02424552)
- Testing
- Vitamin D3
- Where
- 9 sites in Germany
- Volunteers
- 54 people
- Sponsor
- Johannes Gutenberg University Mainz
Pain
Relative Bioavailability and Food Effect Study
Initial studies have used a powder in capsule formulation of PH797804. In future studies an immediate release tablet will be used.
- Trial name
- NCT00827515
- Testing
- PH797804
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer