Clinical trials: Immediate Effect
Chronic Disease, Asthma
Feasibility of Ripple Health Smart Pill Caps in Clinical Settings
The purpose of this research is to determine whether Ripple Health Smart Medicine Bottle Caps can allow for better interface medication administration than traditional pill bottles.
- Trial name
- NCT05192928
- Testing
- Ripple Health Smart Pill Cap
- Where
- 4 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Manan Shukla
Asthma (Diagnosis)
The Effect of a Cold Air Eucapnic Hyperventilation Test on Lower Respiratory Airways in Healthy Volunteers and Patients With Asthma
In this study, we want to evaluate the feasibility and safety of a CAEH test in healthy volunteers and patients with asthma. We want to develop a CAEH test to differentiate patients with different types of asthma and…
- Trial name
- CLARINET (NCT07220928)
- Testing
- Cold air challenge
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Morbid Obesity
Effect of Boussignac CPAP Ventilation on PaO2 and PaO2/FiO2 Ratio in Morbidly Obese Patients Undergoing Bariatric Surgery
The purpose of this study is to determine if the application of Boussignac continuous positive airway pressure (CPAP) immediately after extubation improves PaO2 and PaO2/FiO2 ratio in morbidly obese patients undergoing gastric…
- Trial name
- NCT02297828
- Testing
- Boussignac CPAP, Venturi face mask
- Where
- Portugal
- Volunteers
- 24 people
- Sponsor
- Centro Hospitalar do Porto
Exercise Induced Bronchospasm, Exercise Induced Asthma
Inspiratory Muscle Training on The Severity of Exercise-Induced Bronchoconstriction and Time-Trial Performance (IMT_EIB)
Due to the lack of studies examining the impact of inspiratory muscle training (IMT) on the severity of exercise-induced bronchoconstriction (EIB) and exercise performance, the specific aim of this study is to assess the efficacy…
- Trial name
- IMT_EIB (NCT06336681)
- Testing
- PrO2Fit Device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Indiana University
Asthma
Effects of Pilates Exercises in Asthmatic Patients
Asthma is a chronic respiratory disease with high prevalence worldwide, considered an important cause of morbidity, mortality and high economic costs.
- Trial name
- NCT03670654
- Testing
- Pilates, Muscle stretching
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Healthy Adults
A Study to Learn if a Medicine That Reduces Stomach Acid Affects the Blood Level of Study Medicine PF-08049820 in Healthy Chinese Adults.
This clinical study is designed to evaluate a study medicine called PF-08049820. The main aim is to understand how the body processes this medicine and whether giving it with another medicine, rabeprazole, affects how it behaves.
- Trial name
- NCT07284173
- Testing
- PF-08049820, Rabeprazole
- Where
- 2 sites in China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pfizer
Pneumonia, Pulmonary Fibrosis
Pulmonary Rehabilitation in Non-chronic Obstructive Pulmonary Disease Patients.
To determine the effect of pulmonary rehabilitation on pulmonary function in non-chronic obstructive pulmonary disease patients.To determine the effect of pulmonary rehabilitation on health related quality of life in non-chronic…
- Conditions
- Pneumonia, Pulmonary Fibrosis, Tuberculosis, Bronchiectasis
- Trial name
- NCT05174741
- Testing
- Conventional Chest Physiotherapy, Aerobic training Group
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Asthma
Effects of the Kata® Inhalations-App on Inhaler Handling Errors, Adherence, and Asthma Control in Patients With Asthma.
The Kata® App is a digital therapy assistant for patients with asthma who need to inhale their therapy. Kata features inhalation trainers that shows patients in a simple and understandable way how to improve their inhalation…
- Trial name
- NCT06178341
- Testing
- Kata Inhalations-App
- Where
- 13 sites in Germany
- Volunteers
- 146 people
- Sponsor
- VisionHealth GmbH
Chronic Spontaneous Urticaria
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Single and Multiple Doses of HRS-3095 Oral Administration in Healthy Subjects, as Well as the Effect of HRS-3095 on CYP3A4 Metabolic Enzymes
The study is being conducted to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of HRS-3095 oral administration in healthy subjects.
- Trial name
- NCT07230418
- Testing
- HRS-3095 Tablet
- Where
- China
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Chengdu Suncadia Medicine Co., Ltd.
Food Allergy
OIT Effect on FAQLQ
Patients with food allergy and their parents will answer a food allergy quality of life questionnaire that will be translated to Hebrew and validated.
- Trial name
- NCT02375360
- Testing
- Oral immunotherapy
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Assaf-Harofeh Medical Center
Dental Implant, Tooth Extractions
Effects of Implant Placement Depth (4 mm Versus 6 mm) on Crestal Bone Stability in Immediate Implant Placement: A Clinical Study With 1-Year Post-Restorative Results
The aim of a study was to analyze the effect of implant placement depth (4 mm versus 6 mm below the mid-facial gingival margin) on marginal bone loss (MBL) around implant and implant stability during immediate implant placement…
- Conditions
- Dental Implant, Tooth Extractions, Marginal Bone Loss Around Implants, Primary Stability of the Implants
- Trial name
- NCT07574710
- Testing
- Implants were positioned 4 mm below the mid-facial gingival margin, Implant was placed 6 mm below free gingival margin
- Where
- Lithuania
- Volunteers
- 35 people
- Sponsor
- Tomas Linkevicius
Asthma, Wheezing
Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation
In a randomized clinical trial (RCT) published in JAMA, the investigators have provided evidence that vitamin C supplementation (500 mg daily during pregnancy) ameliorates the effects of maternal smoking during pregnancy on…
- Conditions
- Asthma, Wheezing, In Utero Nicotine, Pulmonary Function
- Trial name
- VCSIP-ECHO (NCT03206710)
- Testing
- No current intervention
- Where
- 2 sites in United States
- Volunteers
- 395 people
- Sponsor
- Oregon Health and Science University
Anaphylaxis, Mastocytosis
Analysis of the Role of IgE Proteoforms in Health and Disease
The goal of this observational study is to evaluate the role of IgE proteoforms in healthy volunteers and in patients with type I allergy, patients with chronic spontaneous urticaria, patients with a recent history of…
- Conditions
- Anaphylaxis, Mastocytosis, X-linked Agammaglobulinaemia, Venom Allergy
- Trial name
- IgE-PhD (NCT07328178)
- Testing
- Blood sample collection
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Asthma and Rhinitis
Follow-up Study to Investigate the Effect of GSK2245035 on Nasal Allergic Reactivity in Subjects Completing Treatment in Study TL7116958
This study will evaluate the duration of effect of GSK2245035 on allergic reactivity by repeating a nasal allergen challenge (NAC) approximately one year after treatment in subjects from TL7116958.
- Trial name
- NCT02446613
- Testing
- Pollen allergen extract
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- GlaxoSmithKline
Allergic Conjunctivitis
A Single-Center Evaluation of the Anti-Inflammatory Effects of Lastacaft as Measured by In-Vivo Confocal Microscopy
A Single-Center Evaluation of the Anti-Inflammatory Effects of Lastacaft ® as Measured by In-Vivo Confocal Microscopy
- Trial name
- NCT02308501
- Testing
- Lastacaft ®
- Volunteers
- 25 people
- Sponsor
- ORA, Inc.
Rhinitis, Allergic, Perennial
Probiotic Administration and Perennial Allergic Rhinitis
The purpose of this study is to evaluate the efficacy of a probiotic strain in improving the quality of life in adult subjects suffering from perennial allergic rhinit.
- Trial name
- NCT01779895
- Testing
- Lactobacillus paracasei probiotic strain
- Where
- Switzerland
- Volunteers
- 64 people
- Sponsor
- Société des Produits Nestlé (SPN)
Eosinophilic Esophagitis
Pediatric Eosinophilic Esophagitis (pedEoE): Effect of Allergen Heat Denaturation on EoE Remission: a Pilot Trial
The objective of the study is to study whether the introduction of heated food products (more specifically heated hen's egg and/or cow's milk) in children with EoE would be possible without re-occurrence of the eosinophilic…
- Trial name
- NCT06381219
- Testing
- Implementation of cow's milk in decreasingly heated forms, Implementation of hen's egg in decreasingly heated forms
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Patients
The Effects of Sphenopalatine Ganglion Acupuncture in Patients With Seasonal Allergic Rhinitis
Sphenopalatine ganglion (SPG)-acupuncture has been shown to exhibit distinct effects in treatment of nasal inflammatory disease.
- Trial name
- NCT03282630
- Testing
- Sphenopalatine ganglion acupuncture
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Tongren Hospital
Asthma
Efficacy of L-menthol on Breathlessness in Asthma
The purpose of this study is to assess the effect of L-menthol on breathlessness and exercise capacity in patients with Asthma.
- Trial name
- Ment-Astma (NCT07500974)
- Testing
- L-menthol
- Where
- 2 sites in Sweden
- Volunteers
- 20 people
- Sponsor
- Region Skane
Asthma, Obstructive Sleep Apnea
Asthma and Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea (OSA) is a common but under-diagnosed form of sleep disordered breathing (SDB). Asthma is a common disease with rising prevalence, which continues to pose significant morbidity and costs.
- Trial name
- NCT01026298
- Testing
- FDA-Approved Treatment
- Where
- United States
- Volunteers
- 744 people
- Sponsor
- University of Wisconsin, Madison
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