Clinical trials: Immediate Effect
Allergic Rhinitis, Phototherapy
Subjects With Clinical Diagnosis of Allergic Rhinitis Were Randomly Divided Into 2 Groups, With Patients in One Group Given One Treatment Session of Red Light Rhinophototherapy, Followed by Medical Treatment. Those in the Second Group Were Treated With Medical Treatment Only.
To investigate the short-term effects of red light rhinophototherapy on nasal patency in patients with a clinical diagnosis of allergic rhinitis using both active anterior rhinomanometry and acoustic rhinometry.
- Trial name
- NCT03752645
- Testing
- Transverse Many Channels Laser Instrument
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taichung Veterans General Hospital
Allergic Rhinitis
The Effect of Allergic Rhinitis on Educational Outcomes
The study will assess the the burden of living with allergic rhinitis (AR) and the effect of AR on school performance for children and adolescents in Denmark.
- Trial name
- NCT05881577
- Testing
- Observational
- Where
- Denmark
- Volunteers
- 150,000 people
- Sponsor
- ALK-Abelló A/S
Drug Hypersensitivity
Establishment of a Registry for Immediate Drug Allergy
Immediate drug hypersensitivity reactions are acute adverse reactions that occur within one hour of drug administration and can result in life-threatening symptoms such as urticaria, angioedema, and anaphylaxis.
- Trial name
- NCT07390370
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Dental Restoration Failure, Postoperative Hypersensitivity
The Effect of Decoupling With Time Technique on the Clinical Performance of Proximal Posterior Composite Restorations
This randomized clinical trial will evaluate whether the decoupling with time technique improves the clinical performance of Class II posterior composite restorations compared with conventional composite restoration techniques.
- Trial name
- DWT (NCT07917572)
- Testing
- Decoupling With Time Technique, Conventional Composite Restoration
- Volunteers
- 50 people
- Sponsor
- Cairo University
Asthma
Usage, Usability & Effect on Adherence and Clinical Outcomes of Text Message Reminders for Adolescents With Asthma
The purpose of this randomized crossover study is to determine the efficacy of participant designed medication reminders on asthma control, asthma related quality of life,and medication adherence.
- Trial name
- NCT01253330
- Testing
- Text Message Reminders
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Atopic Dermatitis
Effect of Oral Steroids on Skin Outcomes in Atopic Dermatitis
Atopic Dermatitis (AD), also known as eczema, is a common skin disease characterized by itchy lesions. The prevalence of AD has increased over the past few decades, with 15-30% of children and 2-10% of adults being affected.
- Trial name
- OSAD (NCT02908698)
- Testing
- Prednisone
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- McMaster University
Postural Balance, Aging
Immediate Effects of Vojta Therapy on Postural Control in Older Adults
This exploratory randomized assessor-blinded study aimed to determine whether a single session of Reflex Locomotion Therapy according to Vojta produces immediate changes in postural control in community-dwelling older adults…
- Conditions
- Postural Balance, Aging, Frailty
- Trial name
- VOJTABALANCE (NCT07829172)
- Testing
- Reflex Locomotion Therapy according to Vojta, Educational Session
- Where
- Chile
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Marianela Alejandra Valenzuela Sandoval
Atopic Dermatitis, Dermatitis Atopic
Dupilumab Skin BArrier Function and LIpidomics STudy in Atopic Dermatitis in China
This is a 16-week, open label, exploratory study designed to investigate dupilumab's effect on skin barrier function as measured by transepidermal water loss (TEWL) before and after skin tape stripping.
- Trial name
- BALISTAD-CN (NCT05624112)
- Testing
- Dupilumab
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sanofi
Dermatitis, Atopic
Drug Drug Interaction Study Evaluating the Effect of Fluvoxamine or Fluconazole on PK and Safety of PF-04965842.
A Phase 1, Open Label, Parallel-Cohort, Randomized, Fixed Sequence Study To Evaluate The Pharmacokinetic Drug Drug Interaction Between PF-04965842 and Fkuvoxamine (cohort 1) or Fluconazole (Cohort 2) in healthy subjects.
- Trial name
- NCT03634345
- Testing
- Period 1 - Day 1: PF-04965842 administered, Period 2: Cohort 1: Fluvoxamine & PF-04965842, Period 2: Cohort 2: Fluconazole & PF-04965842
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Asthma
A Study in Healthy Volunteers and Patients With Mild Asthma to Investigate the Safety, Anti-inflammatory Effect of Inhaled AZD0449
This will be a Phase I, first in human (FIH) study consisting of the following parts: Part 1a (SAD), Part 1b (IV Cohort), Part 2 (Multiple ascending dose (MAD), and Part 3 dry-powder inhalation (DPI)/ Proof of mechanism (PoM).
- Trial name
- NCT03766399
- Testing
- AZD0449
- Where
- 4 sites in Germany, New Zealand and 1 more
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Volunteers
A Study to Assess the Bioavailability and Effect of Food of BMS-986419 Immediate-release Tablet Formulation in Healthy Adult Participants
The purpose of this study is to assess the impact of the BMS-986419 new immediate release (IR) tablet formulation compared to the current enteric (DR) capsule formulation, and to assess the effect of food on the drug levels of…
- Trial name
- NCT05963932
- Testing
- BMS-986419 DR Capsule, BMS-986419 IR Tablet
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Stress Related Disorder, Musculoskeletal Pain
Immediate Effect of Energy Alignment and Mantra on Stress Related Pain in Adolescents
Psychiatrists have expressed concern at the emergence of education as a serious source of stress for school-going children - causing high incidence of deaths by suicide.
- Conditions
- Stress Related Disorder, Musculoskeletal Pain, Headache
- Trial name
- NCT03308630
- Testing
- Yoga based Energy Alignment and Mantra
- Where
- India
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- NMP Medical Research Institute
Cardiac Allograft Vasculopathy
A Study to Compare the Effectiveness of a Drug That Suppresses the Immune System Called Thymoglobulin® in Preventing the Development of a Disease That Affects the Majority of Heart Transplant Recipients Called Cardiac Allograft Vasculopathy (CAV)
The purpose of this study is to test the hypothesis that administering Thymoglobulin® induction therapy early after transplant prevents the development of cardiac allograft vasculopathy (CAV).
- Trial name
- NCT01157949
- Testing
- Thymoglobulin
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Approach/Avoidance Behavior
Theta Phase-specific TMS to Modulate Prefrontal Activity
The purpose of this study is to evaluate the causal link between the phase of ongoing theta oscillations in the prefrontal cortex and approach/avoidance (Ap/Av) behavior in adults using theta phase-specific transcranial magnetic…
- Trial name
- NCT05416138
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Rhinitis, Allergic, Seasonal
Study of Nasal Symptom Relief and Side Effects in Hayfever Patients Treated With Aerius (Desloratadine)(P03442)
The purpose of this study was to test the effectiveness and side effects of desloratadine (Aerius) in patients with hayfever. Patients took desloratadine once a day for 15 days.
- Trial name
- NCT00805584
- Testing
- desloratadine
- Volunteers
- 311 people
- Sponsor
- Organon and Co
ACE Inhibitor-Induced Angioedema
Safety and Efficacy of Conestat Alfa for ACE-Induced Angioedema
Angiotensin-converting enzyme inhibitors (ACE-Is), prescribed most often to treat hypertension, have been used extensively since the 1980s.
- Trial name
- NCT06679426
- Testing
- Conestat Alfa
- Volunteers
- 24 people
- Sponsor
- University of Cincinnati
Asthma
The Additive Anti-inflammatory Effect of Simvastatin in Combination With Inhaled Corticosteroids on p38 MAPK in Asthma
To test whether simvastatin has an additional anti-inflammatory effects on p38 MAPK, a signaling molecule for inflammation in inhaled steroid-treated asthmatics.
- Trial name
- Simvastatin (NCT01266434)
- Testing
- Simvastatin, B1-6-12
- Where
- Thailand
- Volunteers
- 44 people
- Sponsor
- Mahidol University
Tension-Type Headache
Immediate Effects of Suboccipital Muscle Release Combined With Sustained Natural Apophyseal Glides in Patients With Chronic Tension Type Headache
Headache disorder characterized by recurrent headache are among the most common disoredrs of the nervous system. Tension type headache is widely recognized kind of headache that affects 80% of the individuals.
- Trial name
- NCT05883813
- Testing
- sustained natural apophyseal glides (SNAGS), suboccipital muscle release, Supplemental therapy
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Foundation University Islamabad
Seasonal Allergic Rhinitis, Sinusitis
A Study To Investigate If MRI Scanning Is Effective At Seeing What Hayfever Drugs Do In Nasal Passage.
The purpose of this study is to establish whether MRI scanning is a sensitive measure of the effects of existing drug treatments on nasal dimensions following challenge with intranasal allergen in subjects with hayfever.
- Trial name
- NCT00517946
- Testing
- pseudoephedrine hydrochloride, cetirizine hydrochloride
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- GlaxoSmithKline
Cognitive Dysfunction
The Effect of Physostigmine on Cognitive Functioning in the Immediate Period After Sedation for Colonoscopy
The purpose of this study is to determine whether the administration of physostigmine in combination with sedation for colonoscopy can minimize the cognitive decline at the time of hospital discharge
- Trial name
- NCT01121497
- Testing
- Physostigmine
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Rabin Medical Center
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