Clinical trials: Immediate Effect
Medication Adherence, Medication Nonadherence
Determining the Impact of a Medication Delivery Unit on Medication Adherence of Adults With Common Cardiac Conditions
The research study is a randomized controlled trial (RCT). The primary endpoint is to compare medication adherence of adult patients recently hospitalized with a diagnosis of common cardiac conditions who require medication…
- Conditions
- Medication Adherence, Medication Nonadherence, Adverse Reaction to Drug
- Trial name
- EMMA-RCT (NCT01600677)
- Testing
- Computerized medication delivery unit, Usual care
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Pittsburgh
Asthma, Obesity
Effects of Weight Loss in Obese Difficult-to-treat Asthmatics
Sixty percent of patients with difficult to control asthma seen in our outpatient clinic are obese. The impact of weight reduction in this subpopulation of asthmatics has not been studied.
- Conditions
- Asthma, Obesity, Weight Loss
- Trial name
- NCT01047657
- Testing
- Low caloric diet plus orlistat and sibutramine
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- University of Sao Paulo General Hospital
Seasonal Allergic Rhinitis
Montelukast in Seasonal Allergic Rhinitis: Fall 2001 Study (0476-240)
This is a study to evaluate the treatment effect of montelukast 10 mg taken in the morning, versus placebo, in patients with seasonal allergic rhinitis. Loratadine is included in the study as an active control.
- Trial name
- NCT00963469
- Testing
- montelukast sodium, Comparator: loratadine
- Volunteers
- 1,079 people
- Sponsor
- Organon and Co
Neck Pain
Immediate Effect of Cervical Manual Therapy Methods in Patients With Neck Pain
Chronic neck pain is an important health problem in modern society and is frequently encountered today. Approximately 10% of the adult population experiences neck pain at least once in their lives.
- Trial name
- NCT05567302
- Testing
- Manual therapy, myofascial release
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Istanbul Medipol University Hospital
Asthma
Effect of Budesonide / Formoterol Combination in Repeated AMP Provocations
The aim is to study whether the budesonide component within the budesonide/ formoterol combination inhaler has additive value in a model of "slow onset acute asthma" , namely three AMP provocation tests performed on one day
- Trial name
- NCT00272753
- Testing
- budesonide/formoterol Turbuhaler, formoterol Turbuhaler, salbutamol
- Where
- 2 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- AstraZeneca
Asthmatic
Laura Mitchell's Relaxation Versus Papworth Exercise in Ashmatic Patient
Asthma is a lung disease that is characterized by airway obstruction that is reversible either spontaneously or with treatment, airway inflammation, and increase airway responsiveness to a variety of stimuli.
- Trial name
- NCT05915845
- Testing
- Laura Mitchell's Relaxation technique, Papworth exercise
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Pulmonary Disease, Chronic Obstructive
A 5-Period, Single Dose, Phase 1 Study in Healthy Elderly Subjects to Assess Relative Bioavailability and Food Effect of Two Oral Formulations of GSK1325756 (Free Base vs HBr Salt) and Food Effect on the HBr Formulation When Given With Omeprazole
The current study will help to increase our understanding of the pharmacokinetics (PK) of danirixin. The primary objective of the study is to estimate the relative bioavailability of danirixin Hydrobromide (HBr) tablet, when…
- Trial name
- NCT02453022
- Testing
- Danirixin HBr 50 mg IR Tablet, Danirixin FB 50 mg IR Tablet, Prilosec (omeprazole) 40mg Delayed-Release capsule
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Bronchial Asthma, Childhood Asthma
Effect of Multimedia Protocol About Asthma Control
This study aims to evaluate the effect of multimedia protocol about asthma control on asthmatic children's adaptation in the era of climate changes.
- Conditions
- Bronchial Asthma, Childhood Asthma, Climate Change, Multimedia Learning Education
- Trial name
- NCT06974331
- Testing
- Multimedia Protocol about Asthma Control
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Mansoura University
Multi-drug Resistant Tuberculosis
Single-dose Study in Two Panels of Healthy Adult Participants to Assess Immediate-Release and Dispersible Formulations of Pretomanid
This is a single-dose, open-label, randomized, four-period, four-treatment, crossover study in healthy adult subjects.
- Trial name
- NCT04309656
- Testing
- Pretomanid
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Global Alliance for TB Drug Development
Breast Feeding, Counselling
Effects of Individualized Immediate Postnatal Counselling on Exclusive Breast Feeding
Breastfeeding is crucial for the health of both mothers and infants, promoting healthier populations and reducing long-term healthcare costs. To maximize these benefits, education, support, and effective policies are essential.
- Trial name
- NCT06564922
- Testing
- Counselling
- Where
- Ethiopia
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Bule Hora University
Attachment Loss, Tooth,Non Vital
Immediate Verses Delayed Surgical Periodontal Therapy After Endodontic Treatment in Endo Perio Lesion With Communication
The aim of the study is to conduct a prospective randomized clinical trial to evaluate the effect of immediate and delayed surgical periodontal therapy after non-surgical endodontic treatment on periodontal healing of the…
- Trial name
- NCT02630745
- Testing
- Immediate periodontal surgery, Delayed periodontal surgery
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Asthma
Effects of Mometasone Furoate/Formoterol Combination Versus Mometasone Furoate Alone in Persistent Asthmatics (Study P04334AM1)(COMPLETED)
This is a randomized, multi-center, double-blind, double-dummy, placebo-controlled, parallel-group study, evaluating the efficacy of mometasone furoate (MF) /formoterol fumarate (F)[MF/F] metered dose inhaler (MDI) versus MF for…
- Trial name
- NCT00383240
- Testing
- mometasone furoate/formoterol fumarate combination MDI 200/10 mcg BID, Mometasone furoate MDI (MF MDI) 200 mcg, formoterol fumarate 10 mcg
- Volunteers
- 781 people
- Sponsor
- Organon and Co
Asthma
The Effect of Allergen Inhalation on Sputum Myeloid and Plasmacytoid Dendritic Cells in Mild Atopic Asthmatics
Summary: A picture is emerging of dendritic cells migrating through the blood to the airways following allergen inhalation in atopic asthmatics.
- Trial name
- NCT00625989
- Testing
- Aeroallergen
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Hamilton Health Sciences Corporation
Asthma
Effects of Framing on Medication Beliefs, Intentions to Take Medication, Adherence, and Asthma Control
The goal of this study is to examine the effects of framed mobile messages on young adults' beliefs about their daily Inhaled Corticosteroids (ICS), intentions to take their ICS, adherence, and asthma control.
- Trial name
- NCT06033313
- Testing
- Negatively Framed text messages, Positively Framed text messages
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Auburn University
Acute Myocardial Infarction
Effectiveness of Intracoronary Injection of Eptifibatide in Primary Coronary Intervention in STEMI Patients
The achievement of high local concentration of Eptifibatide, a GP 2b3a inhibitor,via direct intracoronary injection, promotes (in vitro) clot disaggregation.
- Trial name
- ICE (NCT00945308)
- Testing
- Eptifibatide
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Asthma
Effects of Leukotriene Modulator Montelukast on Cough Variant Asthma
This study aims to observe the therapeutic effect of leukotriene modulator montelukast alone or combined with inhaled corticosteroid(ICS) on cough variant asthma(CVA). The investigators hypothesize: 1.
- Trial name
- NCT01404013
- Testing
- ICS/LABA, Montelukast, ICS/LABA and Montelukast
- Where
- China
- Volunteers
- 99 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Atopic Dermatitis
Effect of Holly Mangrove Shower Gel in Atopic Dermatitis Patients
Atopic dermatitis is a chronic intermittent inflammatory skin disease. Currently, there are many cosmeceutical skin products in which their major action affects skin hydration and skin barrier function.
- Trial name
- NCT02178215
- Testing
- Holly Mangrove Shower Gel
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Asthma, Asthma, Bronchial
Mechanistic Study of Anti-inflammatory Effects of Fevipiprant in Patients With Eosinophilic Asthma.
This is an exploratory, randomized, subject- and investigator-blinded, placebo-controlled mode-of-action study to demonstrate the anti-inflammatory effects of fevipiprant compared to placebo after 12 weeks of treatment in 48…
- Conditions
- Asthma, Asthma, Bronchial, Bronchial Asthma, Eosinophilia
- Trial name
- NCT03989635
- Testing
- QAW039
- Sponsor
- Novartis Pharmaceuticals
Nasal Polyposis, Asthma
Clinical and Biological Effects of Anti-IgE (Omalizumab) in Patients With Bilateral Nasal Polyposis and Asthma
This pilot study is a double-blinded, randomized controlled, two-centre trial in which subjects will receive 4 to 8 (subcutaneous administered) doses of medication (Omalizumab or placebo) (dose and dosing interval calculated on…
- Trial name
- NCT01393340
- Testing
- Omalizumab
- Where
- 2 sites in Belgium
- Volunteers
- 23 people
- Sponsor
- University Hospital, Ghent
Rhinitis, Allergic, Perennial
The Clinical Effects of Montelukast in Patients With Perennial Allergic Rhinitis (0476-265)
The purpose of this study is to determine the effect of an approved medication on the symptoms of perennial allergic rhinitis (an inflammation of the mucous membrane of the nose similar to that found in hay fever except that…
- Trial name
- NCT00092118
- Testing
- Montelukast
- Volunteers
- 1,992 people
- Sponsor
- Organon and Co
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