Clinical trials: Immediate Effect
Poisoning
Mechanisms of N-acetylcysteine Mediated Vascular Adverse Effects
Paracetamol overdose is the leading cause of acute liver failure in the Western World. N-acetylcysteine (NAC) has been the antidote of choice for over 30 years but its use is associated with adverse effects in 40% of cases.
- Trial name
- NCT01209455
- Testing
- Chlorphenamine and Ranitidine, Paracetamol
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Asthma, Yoga
The Effect of Yoga on Respiratory Functions, Symptom Control and Life Quality of Asthma Patients
This study was conducted to find out the effect of yoga applied to asthma patients on the patients' respiratory functions, symptom control and quality of life.
- Trial name
- NCT04107415
- Testing
- yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Asthma in Children, Exercise Induced Asthma
The Rainbow Study - the Effect of Feedback on Asthmatic Symptom Perception
Asthma is a common childhood disease that is characterized by chronic airway inflammation and episodic expiratory airflow obstruction.
- Trial name
- NCT06702735
- Testing
- Rainbow tool, Feedback
- Where
- Netherlands
- Volunteers
- 39 people
- Sponsor
- Medisch Spectrum Twente
Asthma
Study to Investigate the Effect of PBF-680 on Forced Expiratory Volume in 1 Second (FEV1) in Asthmatic Patients
The present trial is an exploratory study aiming at evaluating the safety, tolerability, and efficacy of a 15-day, once daily administration of 10 mg PBF-680 in subjects with persistent, mild-to-moderate atopic asthma.
- Trial name
- ADENOASMA (NCT03774290)
- Testing
- PBF-680
- Where
- Spain
- Volunteers
- 107 people
- Sponsor
- Palobiofarma SL
Chronic Low-back Pain
Immediate Effects of Two Spinal Manipulative Techniques
The aim of this study is to investigate the instant effects of direct vertabral manipulation and indirect vertebral manipulation techniques on muscles mechanical properties, pressure-pain threshold and joint range of motion in…
- Trial name
- NCT05057091
- Testing
- Group 1 - Maitland's Posterior-Anterior Central Vertebral Manipulation, Group 2- Side-Lying Lumbar Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Alanya Alaaddin Keykubat University
Thoracic Hyperkyphosis
Kinesio Taping in Young Adults With Thoracic Hyperkyphosis
Thoracic hyperkyphosis is a postural disorder characterized by excessive thoracic curvature exceeding 40°, which may negatively affect proprioception, postural alignment, and muscle mechanical properties.
- Trial name
- NCT07888790
- Testing
- Kinesiology Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istinye University
Hereditary Angioedema (HAE)
Study of C1 Inhibitor (Human) for the Prevention of Angioedema Attacks and Treatment of Breakthrough Attacks in Japanese Subjects With Hereditary Angioedema (HAE)
The purpose of this study is to determine if an investigational treatment is safe and well tolerated when administered by intravenous (IV) infusion in Japanese subjects with HAE.
- Trial name
- NCT02865720
- Testing
- CINRYZE 500 U, CINRYZE 1000 U
- Where
- 10 sites in Japan
- Volunteers
- 8 people
- Sponsor
- Shire
Asthma, Status Asthmaticus
Study Evaluating the Safety and Effects of MN-221 in Subjects Experiencing an Acute Exacerbation of Asthma
The objective of this clinical study is to examine the safety and effectiveness of intravenous MN-221 compared to placebo when administered as an adjunct to standard therapy in subjects experiencing an acute exacerbation of…
- Trial name
- NCT00683449
- Testing
- Dose Group 1, Dose Group 2, Dose Group 3
- Where
- 9 sites in United States
- Volunteers
- 29 people
- Sponsor
- MediciNova
Asthma
Effects of Abdominal Binder on Dysnea, Control Pause and Quality of Life in Asthmatic Patients
This study investigates the effects of using an abdominal binder as an adjunct to diaphragmatic breathing in asthma patients. The goal is to determine if the binder improves respiratory mechanics, specifically reducing dyspnea…
- Trial name
- NCT07612384
- Testing
- Abdominal binder -assisted diaphragmatic breathing, Conventional diaphragmatic breathing exercise
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Foundation University Islamabad
Asthma (Diagnosis) With Forward Head Posture
Comparative Effects of Posture Correction Exercises and Papworth Technique in Asthmatic Forward Head Posture
This study aims to evaluating and contrasting the effects of posture correction and papworth technique on dyspnea, chest expansion and quality of life in asthmatic patients with forward head.
- Trial name
- NCT07573904
- Testing
- papworth teachnique, posture correction exercises
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Healthy
Immediate Effects of Myofascial Release on the Quadriceps or Hamstrings on Active Cervical Range of Motion
The purpose of this study is to verify the immediate effects of quadriceps or hamstring myofascial release on the active cervical flexion and extension range of motion.
- Trial name
- NCT05725811
- Testing
- Dynamic foam rolling
- Where
- 2 sites in Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Fernando Pessoa
Asthma
Laminar Airflow in Severe Asthma for Exacerbation Reduction - 48 Month Follow-up.
Temperature-controlled Laminar Airflow (TLA) treatment delivered by the Airsonett treatment device is a new treatment for patients with allergic asthma.
- Trial name
- LASER-48 (NCT02813811)
- Where
- United Kingdom
- Volunteers
- 77 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Healthy
A Comparative Bioavailability/Food Effect Study of Immediate-Release and Extended-Release Tramadol HCl/Acetaminophen Combination Products Following Single-Dose and Multiple-Dose Administration in Healthy Adult Volunteers
The objectives of this two-part study were to compare the single-dose and multiple-dose pharmacokinetics of extended release and immediate-release fixed combination formulations containing tramadol-HCl/acetaminophen and to…
- Trial name
- NCT00973232
- Testing
- DDS-06C (650 mg acetaminophen and 75 mg tramadol HCl), DDS-06C (650 mg acetaminophen and 75 mg tramadol), Zaldiar®
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Labopharm Inc.
Exercise-Induced Bronchospasm
Effects of Montelukast on Occult Exercise-Induced Bronchospasm in Athletes
The purpose of this study is to determine if treatment of exercise-induced Bronchospasm with montelukast will help college athletes train more effectively and thus become more competitive in a non ergogenic manner.
- Trial name
- NCT00375232
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Asthma
Combined Effects of Inspiratory Muscles Training With Pilate Training in Asthma Patients
Asthma is a chronic (long-term) condition that affects the airways in the lungs. The airways are tubes that carry air in and out of your lungs. In asthma the airways can become inflamed and narrowed at times.
- Trial name
- NCT06762236
- Testing
- Pillatate Training
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Schizophrenia
A Study to Evaluate the Effect of Oral Paliperidone Extended-Release and Oral Risperidone Immediate-Release on Cognitive Function in Clinically Stable Patients With Schizophrenia
The purpose of this study is to compare the effect of oral paliperidone extended-release and oral risperidone immediate-release on cognitive function, especially the category fluency of Cognitive Abilities Screening Instrument…
- Trial name
- NCT01670071
- Testing
- Paliperidone extended-release, Risperidone immediate-release
- Where
- 3 sites in Taiwan
- Volunteers
- 17 people
- Sponsor
- Johnson & Johnson Taiwan Ltd
Acquired Dysarthria (Finding)
Immediate Effects of Postural Repositioning on Voice Production Tasks in Seated Individuals With Acquired Dysarthria:
To determine the effectiveness of a single 10-min postural repositioning session on the maximum phonation duration in individuals with acquired dysarthria.
- Trial name
- NCT04520828
- Testing
- postural repositioning
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Rhinitis, Allergic, Perennial
The Clinical Effects of Montelukast in Patients With Perennial Allergic Rhinitis (0476-265)
The purpose of this study is to determine the effect of an approved medication on the symptoms of perennial allergic rhinitis (an inflammation of the mucous membrane of the nose similar to that found in hay fever except that…
- Trial name
- NCT00092118
- Testing
- Montelukast
- Volunteers
- 1,992 people
- Sponsor
- Organon and Co
Delayed Onset Muscle Soreness (DOMS), Inflammation
Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion
The goal of this clinical trial is to learn if applying cold therapy can reduce swelling, inflammation, and pain after physical activity in adults who experience muscle soreness (Delayed Onset Muscle Soreness, or DOMS).
- Conditions
- Delayed Onset Muscle Soreness (DOMS), Inflammation, Muscle Pain, Muscle Damage
- Trial name
- NCT06813690
- Testing
- Cold Therapy with Axanova Cold Hot Pearls Maxi Pack
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Allergic Rhinitis
Free Diving Breathing Training in Allergic Rhinitis
The purpose of this study was to investigate the effects of diver-style breathing training on symptoms, pulmonary function, and respiratory muscle, in patients with allergic rhinitis.
- Trial name
- NCT07455968
- Testing
- Free diving breathing training
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
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