Clinical trials: Immune Health
Immunology
A Randomized, Double-Blind, Placebo-Controlled, Parallel Study to Evaluate the Safety of a Bovine Thymus Nuclear Extract
The goal of this trial is to find out if Thymus Nuclear Extract is safe and well-tolerated in healthy men and women by testing three different dose levels and comparing the results to a placebo.
- Trial name
- NCT06795945
- Testing
- TPG1, TPG2, TPG3
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Standard Process Inc.
Rheumatoid Arthritis, Arthritis, Psoriatic
Golimumab Safety and Surveillance Program Using the Ingenix NHI Database
The participants included in this observational study will be drawn from a research database containing claims and enrollment data for members of a large, geographically diverse US health plan.The objective of this study is to…
- Conditions
- Rheumatoid Arthritis, Arthritis, Psoriatic, Ankylosing Spondylitis
- Trial name
- NCT01081717
- Testing
- systemic non-biological treatments, anti-TNF biologics, golimumab
- Volunteers
- 1,064 people
- Sponsor
- Janssen Biotech, Inc.
HIV Infections
A Study of Combivir Plus Abacavir Plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs
The purpose of this study is to test the effectiveness of Combivir plus abacavir plus 141W94 in patients who previously have used anti-HIV drugs.
- Trial name
- NCT00002217
- Testing
- Lamivudine/Zidovudine, Abacavir sulfate, Amprenavir
- Where
- United States
- Sponsor
- Glaxo Wellcome
Rheumatoid Arthritis
Study Evaluating Health Related Utility in Rheumatoid Arthritis
The purpose of this study is to determine in Australia what effect rheumatoid arthritis has on quality of life, and also to determine the costs that are associated with having rheumatoid arthritis.
- Trial name
- NCT00471874
- Where
- 4 sites in Australia
- Volunteers
- 250 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
HIV/AIDS
PlusCare: Mobile Platform to Increase Linkage to Care in Adolescents Living With HIV/AIDS
While major advancements in medical technology over the past decade have significantly improved the life expectancy of persons infected with human immunodeficiency virus (HIV), HIV-positive youth today face new barriers to the…
- Trial name
- NCT03758066
- Testing
- PlusCare
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Dimagi Inc.
HIV Infections
A Study of Two Anti-HIV Drug Combinations
The purpose of this study is to compare the safety and effectiveness of taking lamivudine (3TC) plus zidovudine (ZDV) plus a protease inhibitor (PI) with taking the 3TC/ZDV combination tablet (Combivir) plus a PI.
- Trial name
- NCT00002203
- Testing
- Lamivudine/Zidovudine, Lamivudine, Zidovudine
- Where
- 7 sites in United States, Puerto Rico
- Sponsor
- Glaxo Wellcome
Rheumatoid Arthritis
Registry for Analysis of Compliance in Colombian Participants With Rheumatoid Arthritis Exposed to Golimumab
The purpose of this study is to describe adherence to golimumab in Colombian participants with rheumatoid arthritis (RA) experiencing adequate treatment response, in a real-world clinical settings.
- Trial name
- Go-Compl-Ar (NCT02414984)
- Testing
- Golimumab
- Where
- 5 sites in Colombia
- Volunteers
- 37 people
- Sponsor
- Janssen-Cilag, S.A.
Non Hodgkin Lymphoma, Breast Cancer
Patient Preference for Pegfilgrastim (Neulasta®) Application Forms
The study aims to compare two application forms (pre-filled syringe and On-body injector) of the same active drug (pegfilgrastim) in adult patients under chemotherapy regarding patient preference and health economics.
- Trial name
- CONVENIENCE (NCT03619993)
- Testing
- On-body injector, Pre-filled syringe
- Where
- 48 sites in Germany
- Volunteers
- 404 people
- Sponsor
- iOMEDICO AG
Asthma
Effectiveness of the Propeller Health (Formerly Asthmapolis) Monitoring System
Propeller Health is collaborating with Dignity Health (formerly Catholic Healthcare West (CHW)) to carry out a focused demonstration project to evaluate the effectiveness and potential cost savings of a deployment of the…
- Trial name
- NCT01509183
- Testing
- Propeller Health System (formerly Asthmapolis System)
- Where
- United States
- Volunteers
- 495 people
- Sponsor
- Reciprocal Labs
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Impacts of Glucose Forecasting
This is a study of individuals with type I or type II diabetes. It is meant to test the effect of using the Diabits app on a participant's blood glucose control.
- Trial name
- NCT04217369
- Testing
- Diabits Predictions
- Volunteers
- 90 people
- Sponsor
- Bio Conscious Technologies Ltd
Multiple Sclerosis
Evaluation of Quality of Life (QoL) in Subjects With Highly Active Relapsing Multiple Sclerosis (MS) (CLARIFY MS)
The main purpose of the study was to assess the health-related quality of life (HRQoL) through the Multiple Sclerosis Quality of Life-54 Questionnaire (MSQoL-54) scale in highly-active relapsing multiple sclerosis (RMS)…
- Trial name
- NCT03369665
- Testing
- Mavenclad®
- Where
- 92 sites in Austria, Belgium and 16 more
- Volunteers
- 485 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Respiratory Disease
A Pilot Study to Assess the Suitability of the HealthBeacon Injection Care Management System (ICMS) as a Remote Therapeutic Monitoring (RTM) Device
This goal of this study is to assess the suitability of the HealthBeacon Injection Care Management System (ICMS) as a Remote Therapeutic Monitoring (RTM) device for patients on injectable medications in the home-setting, for the…
- Trial name
- NCT05592769
- Testing
- HealthBeacon Injection Care Management System (ICMS)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- HealthBeacon Plc
Healthy Adults
Probiotic LR08 Improves Gut and Metabolism
Evaluate the efficacy and safety of LR08 as a dietary supplement compared to a placebo in enhancing intestinal health and immune function in healthy adults.
- Trial name
- NCT06875362
- Testing
- Probiotic
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Multiple Sclerosis
Study of Utilization Patterns of Dimethyl Fumarate in Germany
The primary objective of this study is to estimate the proportion of DMF use that is prescribed "on-label" versus "off-label". The secondary objectives are: To describe the demographic characteristics and medical history of DMF…
- Trial name
- NCT02969304
- Testing
- dimethyl fumarate
- Where
- Germany
- Volunteers
- 930 people
- Sponsor
- Biogen
Age-related Functional Decline, Mild Cognitive Impairment
Health Benefits of Nutraceutical Supplementation in Older Adults.
This study examines a multi-ingredient nutraceutical designed to support several areas of health in older adults, including muscle strength, cognitive function, immune response, and inflammation.
- Trial name
- NCT07534878
- Testing
- Powder containing whey isolate and herbal extracts (30g sachet)
- Where
- India
- Volunteers
- 23 people
- Sponsor
- GPLIFE HEALTHCARE PRIVATE LIMITED
Asthma
Successful Control and Clinical Effectiveness Of SERETIDE(Salmeterol/Fluticasone Propionate) Study In Asthma.(SUCCESS)
The primary study objective is to demonstrate the clinical effectiveness of SERETIDE therapy compared to the current care in management of moderate to severe persistent asthma patients in Korea.
- Trial name
- NCT00480649
- Testing
- Salmeterol/ fluticasone propionate
- Where
- 12 sites in South Korea
- Volunteers
- 424 people
- Sponsor
- GlaxoSmithKline
Intestinal Health
Research on the Improvement of Intestinal and Immune Functions by Probiotics
Evaluate the effectiveness and safety of Limosilactobacillus fermentum LF61 as a food supplement compared to a placebo in improving intestinal and immune functions in healthy adults.
- Trial name
- NCT06873425
- Testing
- Probiotic
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Lymphocytic Leukemia, Chronic
An Observational Study on The Health Related Quality of Life in Patients With Chronic Lymphocytic Leukaemia
This observational study will assess the health related quality of life (HQRL) profiles of patients with chronic lymphocytic leukaemia.
- Trial name
- NCT01395615
- Where
- 5 sites in United Kingdom
- Volunteers
- 34 people
- Sponsor
- Hoffmann-La Roche
Atopic Dermatitis
Use of a Mobile Health App in Managing Pediatric Atopic Dermatitis
A randomized controlled study in children with AD, divided into three groups: a control group without access to the app, an experimental observational group with the app, and an experimental interventional group with potential…
- Trial name
- NCT06412094
- Testing
- Standard care, Access to the "AtopicApp" mobile application, Virtual oversight through the AtopicApp
- Where
- Russia
- Volunteers
- 66 people
- Sponsor
- Avanta Trading Ltd.
Knee Arthritis, Knee Osteoarthritis
Gold Factor on Knee Joint Health and Function
The purpose of this clinical study was to determine whether gold nanoparticles (AuNP) supplement holds clinical value in improving joint health, function, and quality of life for arthritis patients.
- Conditions
- Knee Arthritis, Knee Osteoarthritis, Knee Pain Chronic, Knee Discomfort
- Trial name
- NCT05347602
- Testing
- Gold Factor (Gold Nanoparticles, AuNPs)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- 4Life Research, LLC