Clinical trials: Immune Health
NMDAR Antibody-associated Auto-immune Encephalitis
Psycho-social Impact of Anti-NMDAR Encephalitis
NMDA receptor encephalitis is a rare neurological autoimmune disease with severe neuropsychiatric symptoms, but a typically good functional neurological outcome.
- Trial name
- SAPIENCE (NCT05954468)
- Testing
- standardized and validated surveys
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Lymphoma, Lung Cancer
Self-Management and Activation to Reduce Treatment-Related Toxicities (SMARTCare)
The investigators will undertake a multi-centre, randomized controlled trial to implement and evaluate a proactive model of care (SMARTCare) during active cancer treatment that incorporates self-management support (SMS).
- Conditions
- Lymphoma, Lung Cancer, Colo-rectal Cancer
- Trial name
- NCT03849950
- Testing
- SMARTCare, Control
- Where
- 3 sites in Canada
- Volunteers
- 62 people
- Sponsor
- University Health Network, Toronto
Chronic Pain, HIV
An Observational Study of Distress, Immune Function, and Pain in HIV.
This case-control study focuses on pain in HIV, which is common despite antiretroviral therapy and compromises quality of life, mental health and daily functioning.
- Conditions
- Chronic Pain, HIV, Distress, Emotional, Immune System and Related Disorders
- Trial name
- NCT04757987
- Testing
- Pain
- Where
- South Africa
- Volunteers
- 107 people
- Sponsor
- University of Cape Town
Diabetes Mellitus, Type 1, Fasting
Health Education During Ramadan Fasting in Type 1 Diabetes
Adult Muslims are obliged to start fasting during the month of Ramadan. Fasting entails refraining from all food, drink, tablets and injections(vitamins \& fluids) between sunrise and sunset; a period which varies by geographical…
- Trial name
- NCT03501511
- Testing
- IDF modules, Conversational Maps
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Ain Shams University
Rheumatoid Arthritis
High-intensity Interval Exercise in Rheumatoid Arthritis
Cardiovascular performance and overall fitness can be improved by high-intensity aerobic activity, and these benefits may be achievable by persons with rheumatic diseases.
- Trial name
- RA-HIIT (NCT05768165)
- Testing
- High intensity exercise
- Where
- 2 sites in Sweden
- Volunteers
- 87 people
- Sponsor
- Vastra Gotaland Region
Immunization
Adjuvant Effect of Physical Exercise on Immune Response to COVID-19 Vaccination and Interactions With Stress
The purpose of this study is to evaluate the extent to which a single session of light to moderate intensity exercise performed within 30 minutes after receiving either the initial dose of COVID-19 mRNA vaccine may modify the…
- Trial name
- NCT05213000
- Testing
- Exercise
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Immunosenescence, Sarcopenia
Nutritional Supplementation and Muscle Health: A Pilot Study on Immune Function
The ability of older adults to improve their muscle strength through exercise training appears related to how well their immune system functions.
- Trial name
- NCT01935271
- Testing
- Muscle Armor Supplement
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Central Arkansas Veterans Healthcare System
Tobacco Dependence, HIV Infections
Reducing Ethnic Health Disparities: Motivating HIV+ Latinos to Quit Smoking
The purpose of this study is to develop and evaluate a brief clinic-based culturally tailored smoking cessation treatment for a largely low-income, Latino, HIV+ population.
- Trial name
- AURORA (NCT00503230)
- Testing
- Standard Care Intervention (SCI), Culturally Tailored Intervention (CTI)
- Where
- 8 sites in United States
- Volunteers
- 400 people
- Sponsor
- Butler Hospital
Human Papillomavirus, Human Immunodeficiency Virus
Increasing Uptake of Evidence-Based Screening Services Through CHW-led Multi-modality Intervention
The purpose of this research study is to determine the best way to increase screening for cervical cancer, colorectal cancer, HIV, and Hepatitis C among under screened Hispanic, Haitian and African-American individuals in…
- Conditions
- Human Papillomavirus, Human Immunodeficiency Virus, Hepatitis C, ColoRectal Cancer
- Trial name
- NCT02970136
- Testing
- OraQuick Swab, Fecal Immunochemical Test, OraQuick Fingerstick
- Where
- United States
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- University of Miami
Peri-Implant Health, Peri Implant Mucositis
Impact of Smoking on Immune Responses in Peri-implant Health and Disease
Peri-implant diseases are inflammatory conditions affecting the gums and bone around dental implants. Peri-implant mucositis causes inflammation in the gums, while peri-implantitis can also lead to bone loss and, in severe cases…
- Conditions
- Peri-Implant Health, Peri Implant Mucositis, Peri-implantitis
- Trial name
- NCT07750171
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Gazi University
Allergy
Study of Indoor Air Pollutants and Their Impact in Children's Health and Wellbeing
The goal of this study is to identify and assess in real time the impact of the combined action of various types of air and dust pollutants within a classroom on children's health and quality of life, particularly regarding…
- Trial name
- SynAir-G2 (NCT07402200)
- Testing
- Standardized questionnaires, Lung function tests, Prick tests
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Asthma
Survey on the Effect of Health Related Quality of Life (QOL) Associated With Compliance of Carbocisteine in Asthma Patients
The objectives of this study are to investigate the influence on HR-QOL (SF-36 v2) resulting from the compliance of MUCODYNE Tablets or MUCODYNE DS (Dry Syrup) 50% in asthma patients whose control levels are partly controlled or…
- Trial name
- NCT01693471
- Where
- Japan
- Volunteers
- 179 people
- Sponsor
- Kyorin Pharmaceutical Co.,Ltd
Growth
BIG Study (Brain, Immune, and Gut Health Evaluation of Infants/Young Children Fed Infant Formula, and Later Supplemental Toddler Nutrition, With 5 Specific HMOs)
The purpose of this study is to evaluate the growth and development outcomes of infants fed a new infant formula and toddler drink through 24 months of age.
- Trial name
- NCT04957992
- Testing
- Control Infant Formula, Control Toddler Drink, Experimental Infant Formula
- Where
- 42 sites in United States
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Atopic Dermatitis
The Effect of Nature-based Exposure on the Immune System and Skin Health of Atopic Dermatitis Patients.
The purpose of the study is to explore the effect of nature-based exposure on immunological biomarkers and the condition and symptoms of atopic skin.
- Trial name
- NCT06129136
- Testing
- Nature-based exposure by biodiversity component in lotion.
- Where
- Finland
- Volunteers
- 142 people
- Sponsor
- Uute Scientific Oy
Hiv, Mental Health Issue
Striving Towards EmPowerment and Medication Adherence R01
This is a study for Black women living with HIV to test a counseling program for Black women living with HIV. This participant may be a good fit if the participant is a Black woman, living with HIV, has a history of trauma, and…
- Trial name
- NCT06463886
- Testing
- STEP-AD, Enhanced treatment as usual (E-TAU)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Miami
HIV/AIDS, Sexually Transmitted Infection
GPS: Adaptation Trial of an HIV Prevention Counselling Program for HIV-positive and HIV-negative Gay and Bisexual Men
GPS is a sexual health promotion and HIV prevention peer-delivered counselling program. The GPS program has 4 parts: information provision about HIV and sexually transmitted infections, motivational interviewing counselling…
- Conditions
- HIV/AIDS, Sexually Transmitted Infection, Health Behavior
- Trial name
- NCT03186183
- Testing
- GPS program
- Where
- 6 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Toronto Metropolitan University
Immune Health
Exploring the Role of Almonds in Enhancing Immune Strength
The COVID-19 pandemic highlights the importance of good nutritional status for immune strength and for reducing comorbidities that increase morbidity and mortality of infections.
- Trial name
- NCT05059639
- Testing
- Almond, Pretzel
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- San Diego State University
Histologically Confirmed Classical Hodgkin Lymphoma According to the Current World Health Organisation Classification
The Use of FDG-PET in Patient With Hodgkin Lymphoma: a Population Based Study From Northern Italy
Positron Emission Tomography (PET) represents a step forward in the definition of response to therapy in patients with Hodgkin Lymphoma (HL).
- Trial name
- NCT01248000
- Testing
- FDG-PET
- Where
- Italy
- Volunteers
- 136 people
- Sponsor
- Gruppo Italiano Studio Linfomi
Substance-Related Disorders, Mental Disorder
Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa
Poor engagement in care contributes to HIV- and TB-related morbidity and mortality in South Africa (SA). Community health workers (CHWs) are frontline lay health workers who work to re-engage patients who are lost to follow-up…
- Conditions
- Substance-Related Disorders, Mental Disorder, Social Stigma, Depression
- Trial name
- Siyakhana (NCT05282173)
- Testing
- Siyakhana CHW Training
- Where
- South Africa
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
HIV, AIDS
Smoking Cessation for People Living With HIV/AIDS
In this proposed study with People Living with HIV/AIDS (PLWHA), we will use a stepped care model called a Sequential Multiple Assignment Randomized Trial (SMART) to examine the efficacy of low- and high-intensity smoking…
- Conditions
- HIV, AIDS, Nicotine Dependence
- Trial name
- NCT01965405
- Testing
- Bupropion, Brief Counseling, High-magnitude prize contingency management
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Wayne State University
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