Clinical trials: Immune Health
Family Relations, Mental Health
Mothers Living With HIV and Their Adolescent Children
Context: Mothers living with HIV (MLH) and their children face predictable challenges: maintaining physical and mental health, parenting while ill, and addressing HIV-related stressors.
- Conditions
- Family Relations, Mental Health, Physical Health, Risky Sexual Behavior
- Trial name
- TALK LA (NCT00988390)
- Testing
- Cognitive-behavioral, small-group format sessions
- Volunteers
- 543 people
- Sponsor
- University of California, Los Angeles
Immune Health
Efficacy and Tolerability of Sensoril® in Improving Immunity and Thereby Reducing Incidence of Upper Respiratory Tract Infections
to assess the efficacy and safety of a standardized Withania somnifera extract (Sensoril®) as an immunomodulator in individuals suffering from recurrent URTIs.
- Trial name
- NCT04733924
- Testing
- Aqueous extract of roots plus leaves of Withania somnifera 125 mg, Aqueous extract of roots plus leaves of Withania somnifera 250 mg, Microcrystalline Cellulose
- Where
- 3 sites in India
- Volunteers
- 77 people
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Asthma, Adherence, Medication
Evaluating Efficacy of Smart Device in Assisting With Inhaler Technique and Adherence
Asthma affects over 10 million children in the U.S., and poses a significant health and cost burden. Metered dose inhaler (MDI) is the most common method of treatment.
- Conditions
- Asthma, Adherence, Medication, Childhood Asthma
- Trial name
- MOMMIASTHMA1 (NCT04250779)
- Testing
- CapMedic smart inhaler device, Video-based guidance
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Landon Pediatric Foundation
Cow Milk Allergy
Growth of Infants With Cow's Milk Allergy Fed an Amino Acid-based Formula Containing Two Human Milk Oligosaccharides
The main aim of this study is to provide longitudinal growth data in infants with moderate-to-severe cow's milk allergy fed an amino acid-based formula with two added human milk oligosaccharides.
- Trial name
- PLATYPUS (NCT03661736)
- Testing
- Food for Specific Medical Purpose
- Where
- Australia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
In Utero Drug Exposure
Cardiometabolic Health of Children Exposed to Anti-retroviral Therapy (ART) in Utero
The Human Immunodeficiency Virus (HIV) has been recently linked to increased risk for cardiovascular diseases (CVDs). The prevalence of cardiovascular diseases and its risk factor, hypertension, are very high in African…
- Trial name
- ARTMOMSBABES (NCT04763668)
- Testing
- Pregnant HIV positive women on ARTs, Babies born to HIV positive mothers on ARTs
- Where
- South Africa
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Walter Sisulu University
HIV/AIDS, Mental Health Issue
LinkPositively+ A Mobile Health App Delivered Intervention to Improve HIV Care Outcomes Among Black Women Affected by Mental Health and Violence
The investigative team will conduct a 2-arm randomized control trial to examine the preliminary effect of LinkPositively+ (LPP) an enhanced version of LinkPositively (LP) mobile app on improved HIV care outcomes including…
- Trial name
- LPP Plus (NCT06458660)
- Testing
- LPP+: Mindfulness Meditation Delivered, LP
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Guiding Right, Inc.
HIV Infections, Sexually Transmitted Disease
Effect of HIV/STD Risk Reduction Program on South African Adolescents
This study will evaluate the effect of an HIV/STD risk-reduction program on the sexual behavior of South African adolescents.
- Trial name
- NCT00559403
- Testing
- HIV/STD Risk-Reduction, Health Promotion
- Volunteers
- 1,057 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Crohn Disease
A Smartphone Application for Added Psychological Wellbeing in Crohn's Disease
Psychological intervention by COBMINDEX application to reduce psychological stress among CD patients, fatigue and pain and improve the patients' well being, quality-of-life and disease-coping skills, as well as improvement of the…
- Trial name
- COBMINDEX (NCT06221254)
- Testing
- COBMINDEX digital application, Human therapist (Control)
- Where
- 4 sites in Israel
- Volunteers
- 200 people
- Sponsor
- Soroka University Medical Center
Diabetes Mellitus, Type 1, Metabolic Disorder
A Telematic Program for Optimization of Metabolic Control in Diabetes Mellitus Type 1 (DM1) Patients
A greater visit frequency between the diabetes mellitus 1 (DM1) patient and the medical team increases the possibilities to improve metabolic control. The support of telematic visits can support the patient and the health system.
- Trial name
- NCT01337141
- Testing
- Control, Telecare system
- Where
- 5 sites in Spain
- Volunteers
- 154 people
- Sponsor
- Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders
Myasthenia Gravis
Integrating Art Therapy and Adapted Physical Activity: Toward Improved Quality of Life in Patients With Myasthenia Gravis
Myasthenia Gravis (MG) is a rare neuromuscular disease characterized by fluctuating muscle weakness and excessive fatigability. Although medical treatments have improved, MG continues to significantly impact patients' physical…
- Trial name
- APART-MG (NCT07125105)
- Testing
- Adapted Physical Activity Only, Adapted Physical Activity + Art Therapy
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Universite du Littoral Cote d'Opale
Multiple Sclerosis, Anxiety
Using Patient-Reported Outcomes To Improve the Care of People With Multiple Sclerosis
The proposed trial is a prospective, randomized (1:1) trial plan examining whether more routine and frequent measurement of Patient Related Outcome Measures (PROMs) in the care of patients with MS improves patient depression and…
- Conditions
- Multiple Sclerosis, Anxiety, Depression, Patient Satisfaction
- Trial name
- NCT04979546
- Testing
- Intensive Use of Patient Reported Outcome Measures and Open PROM Availability to Treating Neurologist, Conservative Use of Patient Reported Outcome Measures and Blinded PROM Availability to Treating Neurologist
- Where
- Canada
- Volunteers
- 237 people
- Sponsor
- University of Alberta
Medication Adherence, HIV/AIDS
A Mobile Gaming App to Improve Adherence to PrEP
In this study, the investigators will test the mobile game, Viral Combat, for efficacy and acceptability among diverse participants, ages 15-34 years, receiving PrEP care in clinical settings in New England and Mississippi.
- Trial name
- NCT05762705
- Testing
- Multilevel Gaming Adherence Intervention, Treatment as Usual +
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Type 1 Diabetes
Health Care for Type 1 Diabetes in Developing World
This study is a pilot 2-armed, randomized, open label, clinical trial evaluating the effectiveness of a basal approach to diabetes management as compared to the current standard treatment (regular/NPH).
- Trial name
- NCT01424046
- Testing
- basal insulin glargine, standard therapy
- Where
- Rwanda
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Lupus Erythematosus, Systemic
Women Empowered to Live With Lupus Study
The purpose of this research is to examine whether the Chronic Disease Self-management Program (CDSMP) would improve health outcomes and reduce health care use in African American women with systemic lupus erythematosus (SLE).
- Trial name
- WELL (NCT02988661)
- Testing
- Chronic Disease Self-management Program (CDSMP)
- Where
- United States
- Volunteers
- 699 people
- Sponsor
- Emory University
HIV Infections
Efficacy of Serious Game Interventions on HCV Education for HIV Patients
Hepatitis C transmission has a high rate of infection and re-infection among PLWH men who have sex with men (MSM), and co-infection increases liver and HIV morbidity.
- Trial name
- NCT05497388
- Testing
- Serious Game
- Where
- Taiwan
- Volunteers
- 162 people
- Sponsor
- National Taiwan University Hospital
Nature, Human, Microbial Colonization
Biodiversity Interventions for Assisted Living Centers
Biodiversity is essential for nature and human well-being. Land use has reduced biodiversity in cities, which weakens the functionality of the urban ecosystems and the well-being of citizens.
- Conditions
- Nature, Human, Microbial Colonization, Well-Being, Psychological, Immune System and Related Disorders
- Trial name
- BIWE (NCT06390683)
- Testing
- Rewilding
- Where
- Finland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Natural Resources Institute Finland
Rheumatoid Arthritis (RA), Anxiety
Mobile App-Based Yoga and Meditation in Rheumatoid Arthritis
The goal of this single-blind, randomized controlled trial is to evaluate the clinical effectiveness and short-term economic impact of a mobile application-based, personalized yoga and meditation program in adult patients with…
- Conditions
- Rheumatoid Arthritis (RA), Anxiety, Depression Anxiety Disorder, Mobile Health Technology (mHealth)
- Trial name
- NCT07666594
- Testing
- Mobile App-Based Yoga and Meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Tugba Civi Karaaslan
Cystic Fibrosis, Asthma
Measures of Respiratory Health (MRH)
The Lung Clearance Index, measured by multiple breath washout, is a measure of lung function that is considered a research tool in Canada as the device used to measure it is not approved by Health Canada.
- Conditions
- Cystic Fibrosis, Asthma, Sickle Cell Anemia, Bronchiolitis Obliterans
- Trial name
- MRH (NCT02657837)
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Hematologic Cancer, Colon Cancer
Precision Physical Exercise for Personalized Onco-Hematology.
Physical exercise, particularly strength training, has become an effective strategy to improve physical function, muscle mass, and quality of life in cancer patients.
- Conditions
- Hematologic Cancer, Colon Cancer, Breast Cancer, Lymphoma
- Trial name
- PEPOH (NCT07286539)
- Testing
- Supervised Intervention, Home-based Intervention
- Volunteers
- 150 people
- Sponsor
- University of Salamanca
Intestinal and Lmmune Function Lmproved
Investigating the Efficacy of Probiotics in Enhancing Gastrointestinal and Immunological Health
Evaluate the effectiveness and safety of Ligilactobacillus salivarius LS97 as a food supplement compared to a placebo in improving intestinal and immune functions in healthy adults.
- Trial name
- NCT06886724
- Testing
- Probiotic
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.