Clinical trials: Immune Health
T Cell Response to Dried Plum, Vitamin D Influence on Immune Response
Prebiotics (Dried Plum) and Immune Function in Postmenopausal Women
Prior studies have shown that dietary supplementation with dried plums (also known as prunes) reduces bone loss in postmenopausal women.
- Conditions
- T Cell Response to Dried Plum, Vitamin D Influence on Immune Response, Dried Plum and Immune Function
- Trial name
- NCT07222111
- Testing
- Dried plums
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hiv
Estamos Juntos (We Are Together): Improving HIV Care Delivery by Capacitating Health Care Providers
Health care workers' negative behavior towards patients (likely a reflection of low job satisfaction, frustration with delivering HIV care and treatment in extremely resource-limited settings, and burnout) is one of the primary…
- Trial name
- NCT05938621
- Testing
- behavioral therapy and education
- Where
- Mozambique
- Volunteers
- 28,448 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Anemia, Fever
Assessment of the Effectiveness of New Clinical Guidelines for Differential Diagnosis and Management of Common HIV/AIDS-related Conditions in Mozambique
Utilizing funding through the President´s Emergency Plan for AIDS Relief (PEPFAR) this project seeks to assess the effectiveness of a subset of the new Mozambican clinical guidelines for the diagnosis, initial management, and…
- Conditions
- Anemia, Fever, HIV Positive
- Trial name
- NCT01681914
- Where
- 3 sites in Mozambique
- Volunteers
- 492 people
- Sponsor
- Vanderbilt University
Primary Progressive Multiple Sclerosis (PPMS), Secondary Progressive Multiple Sclerosis (SPMS)
Evaluation of an Online, On Demand Multimodal Wellness Program to Reduce Fatigue and Improve Quality of Life in Progressive Multiple Sclerosis.
The goal of this clinical trial is to learn if an online wellness program can lower fatigue and improve mood and quality of life in people with progressive multiple sclerosis who are 45 to 70 years old and are experiencing…
- Trial name
- DEW (NCT07831928)
- Testing
- Online wellness course and online exercise platform, Usual Care Group
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Iowa
HIV Infections, Substance Use
Women Focused Encounters for Resilience Independence Strength and Eudaimonia
The goal of this combination Type 1 hybrid and observational study is to evaluate the impact of a peer delivered intervention of acceptance and commitment therapy (ACT) + exercise + social support to address the substance…
- Conditions
- HIV Infections, Substance Use, Trauma, Medication Adherence
- Trial name
- WE RISE (NCT06216600)
- Testing
- Acceptance and Commitment Therapy (ACT), Body weight circuit training, Empathetic social support
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Hiv, Sexually Transmitted Diseases
CAMELLIA Cohort: A Longitudinal Study to Understand Sexual Health and Prevention Among Women in Alabama
Pre-exposure prophylaxis (PrEP) is an important biomedical human immunodeficiency virus (HIV) prevention tool and may particularly benefit black, cis and trans-gender women, who are at an increased risk for HIV and Sexually…
- Trial name
- CAMELLIA (NCT05463692)
- Testing
- Camelia Cohort
- Where
- United States
- Volunteers
- 830 people
- Sponsor
- University of Alabama at Birmingham
Autoimmune Hepatitis, Primary Sclerosing Cholangitis
A-LiNK: Improving Outcomes in Autoimmune Liver Disease
The Autoimmune Liver disease Network for Kids (A-LiNK) is a multi-institutional group with the mission to deliver the best care to kids with pediatric autoimmune liver disease (AILD).
- Trial name
- ALINK (NCT05750498)
- Testing
- No interventions
- Where
- 8 sites in United States
- Volunteers
- 800 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
HIV Infections
The Cheeky Study: A Novel Delivery System for CAB-RPV LA
This is a single-arm implementation study of a novel integrated delivery model of CAB-RPV LA for transwomen living with HIV.
- Trial name
- NCT05979714
- Testing
- Patient-centered injection site, Patient-centered adherence support, Provider education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Public Health Foundation Enterprises, Inc.
Nursing Caries
Effects of Virtual Reality on Sleep Quality and Mental Well-being
It is known that being in natural environments helps increase a person's well-being. It may not always be easy for individuals with neurological diseases to reach these environments due to their mobility limitations, other…
- Trial name
- NCT06074419
- Testing
- Occulus quest 2 virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Effectiveness
A Study on the Efficacy and Safety of Telitacicept in the Treatment of Children Ocular Myasthenia Gravis
Under conventional treatment regimens, pediatric ocular myasthenia gravis (OMG) is prone to relapse and is associated with corticosteroid-related adverse effects, indicating an unmet clinical need.
- Trial name
- NCT07298928
- Testing
- Telitacicept
- Where
- 3 sites in China
- Volunteers
- 30 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Juvenile Idiopathic Arthritis
An Investigation Into the Relationship Between Dietary Intake and Health-related Quality of Life in Children and Young People With Juvenile Idiopathic Arthritis
"Physical activity and diet in children and young people with arthritis" A qualitative study of exploring stake holder's experiences.
- Trial name
- JIA (NCT04903067)
- Where
- United Kingdom
- Volunteers
- 99 people
- Sponsor
- Oxford Brookes University
Multiple Sclerosis
Electrical Brain Stimulation for Treatment of Secondary Symptoms in Multiple Sclerosis
Multiple Sclerosis (MS) is an autoimmune disease associated with physical disability, psychological impairment, and cognitive dysfunction. As a result, the disease burden is high, and treatment options are limited.
- Trial name
- NCT06401928
- Testing
- transcranial direct current stimulation, transcranial direct current stimulation combined with cognitive training
- Where
- Iran
- Volunteers
- 53 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
HIV/AIDS, Mental Health Issue
HIV + Service Delivery and Telemedicine Through Effective PROs
This study will examine the impact of using a multicomponent intervention (patient reported outcomes, training, and telemedicine) to assist with the management of Mental Health (MH) and Substance Use Disorders (SUD) among people…
- Conditions
- HIV/AIDS, Mental Health Issue, Substance Use Disorders
- Trial name
- HIV+STEP (NCT04489667)
- Testing
- +STEP Implementation
- Sponsor
- University of Alabama at Birmingham
Rheumatoid Arthritis
Prospective Observational Study of Filgotinib in Subjects With Rheumatoid Arthritis
An observational study to describe the effectiveness, safety, and patient-reported outcomes in patients with moderate to severe active rheumatoid arthritis (RA) receiving filgotinib in real-world setting.
- Trial name
- FILOSOPHY (NCT04871919)
- Testing
- Filgotinib
- Where
- 89 sites in Belgium, Germany and 4 more
- Volunteers
- 1,304 people
- Sponsor
- Alfasigma S.p.A.
HIV Infections, Sexually Transmitted Infections
Utilization of HIV Clinical Services in Rural India
This community-based clinical trial based in two districts of rural Maharashtra, India compares utilization of an intervention model of "fully-decentralized," or rural primary clinic-based, HIV testing and care services, with a…
- Trial name
- NCT00554567
- Testing
- HIV Testing and Care Services
- Where
- India
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Institute of Health Management, Pachod, India
Hypersensitivity Pneumonitis, Chronic Hypersensitivity Pneumonitis
Assessing Health Related Quality of Life in Hypersensitivity Pneumonitis
The objective of this study is to administer and validate a disease specific health related quality of life (HRQOL) survey for patients with Chronic Hypersensitivity Pneumonitis (CHP).
- Conditions
- Hypersensitivity Pneumonitis, Chronic Hypersensitivity Pneumonitis, Interstitial Lung Disease, Extrinsic Allergic Alveolitis
- Trial name
- CHP-HRQOL (NCT04273867)
- Testing
- Chronic Hypersensitivity Pneumonitis Health Related Quality of Life Survey Instrument
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Weill Medical College of Cornell University
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Ulcerative Colitis (UC), IBD (Inflammatory Bowel Disease)
The Prospective Improved Vitamin D Study for Inflammatory Bowel Disease Patients
The aim of this clinical trial is to gain a better understanding of the effect of Vitamin D supplementation on disease activity and overall health. The main questions it aims to answer are: 1.
- Conditions
- Ulcerative Colitis (UC), IBD (Inflammatory Bowel Disease), Crohn Disease (CD)
- Trial name
- PIVD (NCT07177157)
- Testing
- Vitamin D3 (Cholecalciferol)
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Terry Ponich
Rheumatoid Arthritis
High-intensity Interval Exercise in Rheumatoid Arthritis
Cardiovascular performance and overall fitness can be improved by high-intensity aerobic activity, and these benefits may be achievable by persons with rheumatic diseases.
- Trial name
- RA-HIIT (NCT05768165)
- Testing
- High intensity exercise
- Where
- 2 sites in Sweden
- Volunteers
- 87 people
- Sponsor
- Vastra Gotaland Region
Multiple Myeloma, Refractory Multiple Myeloma
Real World Insights During Treatment for Relapsed/Refractory Multiple Myeloma with Isatuximab
This descriptive study aims to evaluate the experience of adults with relapsed or refractory multiple myeloma receiving standard of care isatuximab-irfc through collection of quantitative, qualitative and wearable data.
- Trial name
- NCT05053607
- Testing
- Digital Health Coaching Program, Fitbit
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Pack Health
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