Clinical trials: Immune Health
Asthma
A Randomized Controlled Trial of AppS to Home Monitor Your Asthma
The objective of this study is to design, implement, and evaluate the impact of an adapted health information technology(IT)-enabled practice model for asthma symptom monitoring using patient-reported outcomes (PROs) in a primary…
- Trial name
- ASTHMA (NCT04401332)
- Testing
- Mobile health app
- Where
- United States
- Volunteers
- 413 people
- Sponsor
- RAND
Non-Hodgkin Lymphoma
PEARL Study: Improvement of Non-Hodgkin's Lymphoma Care
The main objective of the proposed study is to assess the effectiveness, feasibility and costs of a tailored strategy (developed in accordance with the barriers found and current practice) to improve care for patients with…
- Trial name
- NCT01562509
- Testing
- Implementation tools, Standard intervention
- Where
- Netherlands
- Volunteers
- 418 people
- Sponsor
- Radboud University Medical Center
Thyroiditis, Autoimmune
Evaluating the Dietary Supplement Anatabloc in Thyroid Health-ASAP (Antabloc Supplementation Autoimmune Prevention)
This is a study to evaluate the safety, tolerability, and potential effects of Anatabloc dietary supplementation on antithyroid autoantibodies, thyroid structure, and thyroid function in subjects with autoimmune thyroiditis.
- Trial name
- ASAP (NCT01551498)
- Testing
- Anatabloc Supplement
- Where
- 9 sites in United States
- Volunteers
- 165 people
- Sponsor
- Rock Creek Pharmaceuticals, Inc.
Air Pollution, mHealth Intervention
1/2- Bangladesh Center for Global Environmental and Occupational Health- Bangladesh
Almost 3 billion people worldwide, including 89% people in Bangladesh, are exposed to harmful household air pollutants (HAP) emitted from combustion of biomass (wood, agricultural residue, cow dung, etc.) fuel use for cooking.
- Conditions
- Air Pollution, mHealth Intervention, Cardiopulmonary Function, Immune Function
- Trial name
- GEOHealth-II (NCT05570552)
- Testing
- mHealth based behavioral change communication intervention
- Where
- Bangladesh
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Prostate Cancer
Impact of Yoga As Complementary Therapy in Patients Undergoing Radical Prostatectomy
The researchers hope to learn if yoga complementary therapy would improve health-related quality of life, recovery of urinary continence and erectile function in patients who underwent prostate cancer surgery (i.e.
- Trial name
- NCT02620033
- Testing
- Yoga therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
HIV Infections, Hepatitis C
Tajik Migrant Health Education Study
This study will test the efficacy of a peer-education prevention intervention to reduce risky drug, alcohol, and sexual behaviors among male Tajik labor migrants who inject drugs (MWID) while working in Moscow.
- Conditions
- HIV Infections, Hepatitis C, Risky Health Behavior, Risk Reduction Behavior
- Trial name
- NCT04853394
- Testing
- MASLIHAT, TANSIHAT
- Where
- Russia
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
HIV
Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health
This is a partially randomized, open-label phase 1 study to evaluate the safety and immunogenicity of a priming regimen of 426c.Mod.Core-C4b adjuvanted with 3M-052 AF + Alum followed by boosts with HxB2.WT.Core-C4b adjuvanted…
- Trial name
- NCT06796686
- Testing
- 426c.Mod.Core-C4b, HxB2.WT.Core-C4b, 3M-052-AF adjuvant
- Where
- 6 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
A Study of the Effects of Advantage 24 on the Rectum
The purpose of this study is to see if it is safe and acceptable for homosexual male couples, where both partners have the same HIV status, to use Advantage 24 during anal intercourse.
- Trial name
- NCT00000929
- Testing
- Nonoxynol-9
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma
Airway Inflammation and Disease Burden in Asthmatic Smokers
Aim : To compare, among patients with an uncontrolled moderate to severe asthma, the blood eosinophil levels of smokers and non-smokers.
- Trial name
- NCT02833727
- Testing
- Smoking
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Université de Montréal
Asthma
The Clinical and Laboratory Phenotypes of Severe Asthma Patients in Clalit Health Services Haifa
Asthma is a chronic illness characterized by inflammation of the airways. Severe asthma is defined in the literature as asthma not controlled by medication.
- Trial name
- NCT01741805
- Testing
- Severe Asthma
- Where
- Israel
- Sponsor
- Carmel Medical Center
Asthma (Diagnosis), Inhaler Technique
Using a Digital Spacer for Inhaler Technique Education in Pediatric Asthma
This pilot study evaluates the feasibility, usability, and potential effect of the aflo™ Smart Spacer platform in children aged 6-18 with uncontrolled asthma using pMDIs and spacers.
- Conditions
- Asthma (Diagnosis), Inhaler Technique, Pediatric Asthma
- Trial name
- INSPIRE-KIDS (NCT07803042)
- Testing
- Aflo™ Smart Spacer
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- University Medical Center Groningen
Lupus Nephritis (LN), Lupus Nephritis - WHO Class III
Safety and Efficacy of ONT01 in Lupus
ONT01 is a drug that is being studied for the treatment of Lupus Nephritis (LN) and Systemic Lupus Erythematosus (SLE) and is not approved by the FDA.
- Conditions
- Lupus Nephritis (LN), Lupus Nephritis - WHO Class III, Lupus Nephritis - WHO Class IV, Lupus Nephritis - World Health Organization (WHO) Class III
- Trial name
- NCT07107659
- Testing
- ONT01 is a small molecule CD11b modulator.
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Hospital for Special Surgery, New York
Rheumatoid Arthritis
Patient Rheumatoid Arthritis Social Support Study
The goal of PARASS is to develop a network of increased social support for Rheumatoid Arthritis (RA) patients that will improve patient outcomes and further promote understanding of RA among physicians and patients in the clinic…
- Trial name
- PARASS (NCT01525654)
- Testing
- Peer Support Program
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Multiple Sclerosis, Relapsing-Remitting
An Observational Study Comparing Multiple Sclerosis International Quality of Life Questionnaire (MusiQoL) and Multiple Sclerosis Quality of Life-54 Instrument (MSQOL-54) in Relapsing Multiple Sclerosis (RMS) Patients on Long-term Rebif® Therapy
Significant data from placebo-controlled clinical trials have demonstrated the efficacy of Rebif in relapsing remitting multiple sclerosis (RRMS) with reduction in relapse rate, delay in disability progression, and reduction in…
- Trial name
- COMPARE (NCT01141751)
- Volunteers
- 334 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
HIV/AIDS, Infant Morbidity
Impact of Point-of-Care EID for HIV-Exposed Infants
This mixed methods study will utilize a randomized step-wedge design to assess the impact of point-of-care (POC) versus conventional early infant diagnosis (EID) on key outcomes including timely return of results to caregivers…
- Conditions
- HIV/AIDS, Infant Morbidity, Pediatric HIV Infection, Transmission, Perinatal Infection
- Trial name
- POC-EID (NCT03824067)
- Testing
- Point of Care Early Infant Diagnosis, Standard of Care Early Infant Diagnosis
- Where
- 2 sites in Kenya, Zimbabwe
- Volunteers
- 9,539 people
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
Acquired Immunodeficiency Syndrome, HIV/AIDS
Technological Intervention for Reducing Alcohol Use Among People Living With HIV/AIDS
While advances in medication have led to greatly improved outcomes for people living with HIV/AIDS, less than one-third of all people living with the disease are adherent enough to their medication to achieve viral suppression.
- Conditions
- Acquired Immunodeficiency Syndrome, HIV/AIDS, Alcohol Drinking
- Trial name
- TRAC (NCT03746600)
- Testing
- Project TRAC: Tracking and Reducing Alcohol Consumption
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Carolyn Lauckner
Rheumatoid Arthritis
Arthritis Health Journal Proof of Concept Study
The purpose of this study is to determine whether an online patient passport tool called the Arthritis Health Journal can assist people with rheumatoid arthritis in managing their disease.
- Trial name
- AHJ (NCT01941433)
- Testing
- Arthritis Health Journal
- Where
- Canada
- Volunteers
- 95 people
- Sponsor
- University of British Columbia
Lupus Erythematosus, Systemic
Pilot Study to Investigate Contemplative Intervention in Lupus Patients
The study tests whether contemplative-based intervention can modify pathogenic processes in participants with Lupus. Techniques such as meditation, mindfulness and yoga may have an impact on the disease and may decrease…
- Trial name
- LUPP (NCT03103243)
- Testing
- Mindfulness Based Group Sessions
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Human Immunodeficiency Virus
Music for Health Project
The overall goal of this project is to use technology to improve adherence to antiretroviral therapy (ART)and increase access to ART adherence care for those HIV+ persons living in rural areas.
- Trial name
- MFH (NCT01786148)
- Testing
- mobile phone application
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Emory University
Eczema, Atopic Dermatitis
Studies of Skin Microbes in Healthy People and in People With Skin Conditions
This study will examine microbes (e.g., bacteria, fungi, viruses) that live on human skin and how microbes contribute to health and disease.
- Trial name
- NCT00605878
- Where
- United States
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
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