Clinical trials: Immune Health
Type 1 Diabetes Mellitus
Effectiveness of The Health Care CEO App for T1D
The present study aims to evaluate the intervention effectiveness of the Healthcare Chief Executive Officer mobile application(Healthcare CEO app) in patients with type 1 diabetes transitioning from adolescence to early adulthood.
- Trial name
- NCT05022875
- Testing
- Healthcare CEO app- for experimental app intervention, Healthcare CEO app-for control app intervention
- Where
- Taiwan
- Volunteers
- 96 people
- Sponsor
- Chang Gung University
Type 1 Diabetes Mellitus
Feasibility Study Using Zone-MPC Controller, HMS and Technosphere® Insulin Inhalation System From MannnKind Corp
This clinical trial is a feasibility study to assess the performance of an Artificial Pancreas (AP) device using the Artificial Pancreas System (APS©) platform for subjects with type 1 diabetes using rapid-acting insulin as well…
- Trial name
- NCT01874392
- Testing
- Investigational inhaled insulin (Technosphere), Artificial Pancreas (AP) device (APS©)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Sansum Diabetes Research Institute
Healthy Individuals, Allergic Rhinitis
Health Effects of Wood Smoke and Traffic-Related Air Pollution Exposures: a Necessary Comparison
Accumulating evidence demonstrates that breathing air pollutants leads to devastating increases in sickness and death worldwide over time.
- Trial name
- WADE (NCT06749093)
- Testing
- Filtered Air (FA), Wood Smoke (WS), Diesel Exhaust (DE)
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Diabetes Mellitus, Type 1 Diabetes, Mobile Health Platform
Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes
The goal of this clinical trial is to examine the feasibility and effectiveness of a tele-diabetes remote monitoring system on managing type 1 diabetes (T1DM) among children and adolescents.
- Conditions
- Diabetes Mellitus, Type 1 Diabetes, Mobile Health Platform, Mobile Health Technology (mHealth), Mobile Health
- Trial name
- NCT07828106
- Testing
- Tele-diabetes Remote System
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Hiv, Cardiovascular Diseases
Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV
Older people with HIV (OPWH) are disproportionately impacted by cardiovascular disease (CVD) attributable to behavioral risk factors, and chronic HIV immune dysregulation resulting inflammation.
- Trial name
- OM-OH (NCT06001814)
- Testing
- One-Mind One-Heart, Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy
Almonds: Digestive Health and Immune Function of Adults and Children
The purpose of this study is to determine whether incorporating almonds into the diets of families with young children will induce beneficial changes in gastrointestinal function, the fecal microbiota profile, and immune and…
- Trial name
- NCT01973595
- Testing
- Almonds, Then no almonds, No Almonds, Then almonds
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Florida
Neuromyelitis Optica Spectrum Disorder
CorEvitas SPHERES (Synergy of Prospective Health & Experimental Research for Emerging Solutions) Registry for Neuromyelitis Optica Spectrum Disorder (NMOSD)
This is a Prospective, observational research study for patients with NMOSD under the care of a licensed neurologist. Approximately 800 patients and 35 clinical sites in North America will be recruited to participate with no…
- Trial name
- NCT04886492
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- CorEvitas
Depression, HIV
Implementing Depression and Adherence Treatment
The goal of this clinical trial is to compare a core set and enhanced set of implementation strategies in increasing the reach of evidence-based treatments to patients with HIV and depression.
- Conditions
- Depression, HIV, Adherence, Treatment, AIDS
- Trial name
- NCT07032363
- Testing
- Core Implementation Strategies, Enhanced Implementation Strategies
- Where
- South Africa
- Volunteers
- 10 people
- Sponsor
- University of Miami
Human Immunodeficiency Virus, Smoking Cessation
V+PSF-M for Tobacco Cessation in HIV Care in India
The goal of this research study is to test an intervention to help quit tobacco use in participants with Human Immunodeficiency Virus (HIV).
- Conditions
- Human Immunodeficiency Virus, Smoking Cessation, Smoking, Tobacco
- Trial name
- NCT05786547
- Testing
- Varenicline, Positively Smoke Free Mobile (PSF-M), Standard Care
- Where
- 2 sites in United States, India
- Volunteers
- 400 people
- Sponsor
- University of Colorado, Denver
HIV Infection
Traditional Healer-initiated HIV Counseling and Testing in South Africa
The objective of this proposal is to conduct a pilot test of a program aimed at training traditional healers to conduct HIV testing and implementing HIV testing among people living in Bushbuckridge, South Africa.
- Trial name
- NCT05079347
- Testing
- HIV rapid test
- Where
- South Africa
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Multiple Sclerosis
Therapeutic Adherence of Multiple Sclerosis Patients
The goal of this study is to assess the role of sociocognitive and interpersonal factors in the therapeutic adherence of multiple sclerosis patients.
- Trial name
- FELSA-SEP (NCT04837352)
- Testing
- Study of the role of sociocognitive factors
- Where
- 4 sites in France
- Volunteers
- 153 people
- Sponsor
- Lille Catholic University
Cancer, Cancer Metastatic
Evaluating the Effect of a Mobile Audio Companion (Elly) to Reduce Anxiety in Cancer Patients
This is a single-arm, prospective, interventional study in cancer survivors and patients to examine the feasibility of a mobile health application, Elly (Elly Health Inc.), to reduce levels of anxiety, stress, loneliness, and…
- Conditions
- Cancer, Cancer Metastatic, Neoplasms, Breast Cancer
- Trial name
- NCT04604158
- Testing
- Elly Mobile Phone Application
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Gillian Gresham
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
HIV/AIDS, Smoking Cessation
Learn to Quit-HIV Pilot Study
The study team will conduct a feasibility, acceptability, and preliminary efficacy trial comparing Learn to Quit-HIV (n=30) to an app based on U.S.
- Conditions
- HIV/AIDS, Smoking Cessation, Tobacco Use Disorder
- Trial name
- NCT04609514
- Testing
- Learn to Quit-HIV, QuitGuide, Nicotine patch
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Duke University
Inflammation, Nutrition, Healthy
Probiotic Beer to Enhance Gut Health and Immune System Function
This study investigates the immunological and gut microbiome effects of moderate probiotic beer consumption.
- Trial name
- PBEER (NCT05401604)
- Testing
- Moderate probiotic beer consumption, Moderate normal beer consumption
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Idiopathic Thrombocytopenic Purpura (ITP), Immune Thrombocytopenic Purpura (ITP)
Clinical Trial of Rituximab in Children and Adolescents With Chronic Idiopathic Thrombocytopenic Purpura (ITP)
The purpose of the study is to evaluate the safety and efficacy of rituximab in children ages 18 months to 18 years, who have severe, chronic ITP.
- Trial name
- NCT01713738
- Testing
- rituximab
- Where
- 9 sites in United States
- Volunteers
- 36 people
- Sponsor
- Neufeld, Ellis J, MD, PhD
Medication Adherence
China Adherence Through Technology Study
The CATS project is designed to increase understanding of interventions that are feasible and effective in helping injection drug users (IDU) or other patients at high risk of poor medication adherence who are HIV-positive to…
- Trial name
- CATS (NCT01722552)
- Testing
- adherence feedback, standard of care
- Where
- 2 sites in United States, China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boston University
Bone Cancer, Brain Cancer
Enhanced Assistance During Radiotherapy for Unmet Essential Needs
This is a prospective single-arm study of an enhanced assistance intervention for patients with unmet essential needs undergoing >10 fractions of radiotherapy comparing delay-free completion of radiotherapy in study participants…
- Conditions
- Bone Cancer, Brain Cancer, Colorectal Cancer, Esophagus Cancer
- Trial name
- EARN (NCT06582849)
- Testing
- Standard assistance, Enhanced assistance
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Washington University School of Medicine
HIV Infections, Health Literacy
Trial Embedded in an Electronic Personal Medical Health Records
This is a research study to determine if a personal health record, called myHERO, will help improve health. A personal health record is a secure internet (also called online) tool that contains personal health information like…
- Trial name
- NCT00972348
- Testing
- Online access to a personal health record, No access to the PHR
- Where
- United States
- Volunteers
- 338 people
- Sponsor
- University of California, San Francisco
Rheumatoid Arthritis
Oral Health Assessment in Rheumatoid Arthritis and Other Autoimmune Diseases-- Anti- TNF Substudy
The objective of this study is to evaluate the effect of Tumor Necrosis Factor (TNF) inhibition on oral parameters in patients with RA and to examine changes in levels of proinflammatory cytokines in serum, gingival crevicular…
- Trial name
- NCT01698515
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University