Clinical trials: Immune Health
Systemic Lupus Erythematosus, Contraception
The HOP-STEP Intervention: Improving Maternal Health in Women With Lupus sIRB
While the HOP-STEP (Healthy Outcomes in Pregnancy with SLE Through Education of Providers) program has been demonstrated to be effective in improving provider confidence, increasing contraception documentation, and facilitating…
- Trial name
- HOP-STEPsIRB (NCT05818254)
- Testing
- HOP-STEP (Healthy Outcomes in Pregnancy with SLE Through Education of Providers) Intervention, Routine Care
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Duke University
Moderate and High Cardiovascular Risk
Effectiveness of Financial Incentives and Text Messages to Improve Health Care in Population With Moderate and High Cardiovascular Risk
Cardiovascular diseases are increasing throughout the developing world and are the cause of almost 16.7 million deaths each year, of which 80% occur in low and middle-income countries.
- Trial name
- NCT03300154
- Testing
- Financial incentives, Framing (SMS)
- Where
- 9 sites in Argentina
- Volunteers
- 917 people
- Sponsor
- Institute for Clinical Effectiveness and Health Policy
Asthma, Communication
Using IT to Improve Access, Communication and Asthma in African American and Hispanic/Latino Adults
Background: Asthma morbidity is high in inner-city minority adults, despite the existence of efficacious therapy. Tailored, patient-centered interventions are needed to improve access to care and patient-provider communication.
- Trial name
- NCT02086565
- Testing
- Portal training and home visits, Portal training
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- University of Pennsylvania
Opioid-use Disorder, Adherence, Medication
Social Networks and Methadone Maintenance Treatment Retention and Antiretroviral Therapy Retention in Tanzania
Investigators will adapt the Brief Social Behaviour and Network Therapy (B-SBNT) intervention developed to facilitate recovery among people receiving medication-assisted treatment for opioid use disorder in the United Kingdom.
- Conditions
- Opioid-use Disorder, Adherence, Medication, HIV Infections
- Trial name
- NCT04479475
- Testing
- Supportive care through community support persons
- Where
- Tanzania
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Allergy to Fish, Allergy
Anisakis Blastocystis Cryptosporidium Fish Serology
Anisakidae frequently infect fish species that are commonly eaten by humans. Some of them are recognized as zoonotic diseases agents, and have a high impact on human health.
- Conditions
- Allergy to Fish, Allergy, Anisakis
- Trial name
- ABCFish2 (NCT02666092)
- Testing
- Questionnaire, Detection of anti-Anisakis and anti-fish antibodies
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Electrode Site Reaction, Therapy
Functional Electrostimulation on the Upper Lip in Multiple Sclerosis
Multiple sclerosis (MS) is an autoimmune disease where immune cells attack the body, triggering an inflammatory response. A study comparing multifield FES and conventional FES on upper extremity motor skills and functional…
- Conditions
- Electrode Site Reaction, Therapy, Directly Observed Therapy
- Trial name
- EM/2024 (NCT06638775)
- Testing
- Fesia Grasp, GLOBUS ELITE
- Volunteers
- 30 people
- Sponsor
- Universidad de Burgos
Type1diabetes
The Current Health Status of Patients Living With Type 1 Diabetes From the LMC Diabetes Patient Registry
This retrospective study uses the Canadian LMC Diabetes Registry to describe the current health status of Canadians with type 1 diabetes.
- Trial name
- NCT04162067
- Where
- Canada
- Volunteers
- 3,600 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Rheumatoid Arthritis
Impact Of RA Therapy Compliance On Patient-Reported Outcomes
Several observational studies have evaluated the comparative treatment costs associated with each agent, particularly those within the anti-TNF class, but few have evaluated the impact of therapy compliance, persistence…
- Trial name
- NCT01438892
- Testing
- tDMARDs, biodmards
- Volunteers
- 396 people
- Sponsor
- Pfizer
Tuberculosis, Pediatric ALL
Patient Centered Intervention to Prevent Tuberculosis Among Children Under Five Years Old
Isoniazid preventive therapy (IPT) reduces the risk of tuberculosis in 60%. Young children are at higher risk of developing severe forms of TB, though this can be prevented with a full course of IPT.
- Conditions
- Tuberculosis, Pediatric ALL, Behavior, Health
- Trial name
- NCT03881228
- Testing
- Increasing the completion of IPT
- Where
- Peru
- Volunteers
- 356 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Asthma Childhood, Exercise
Active Airways for Children and Young People With Asthma
What is this study about? The investigators want to see if exercise and education sessions can help children and young people (aged 10-17) with asthma, manage the participants asthma better.
- Conditions
- Asthma Childhood, Exercise, Children
- Trial name
- NCT07643753
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, education
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Leicester
HIV Infections, Substance Use
Women Focused Encounters for Resilience Independence Strength and Eudaimonia
The goal of this combination Type 1 hybrid and observational study is to evaluate the impact of a peer delivered intervention of acceptance and commitment therapy (ACT) + exercise + social support to address the substance…
- Conditions
- HIV Infections, Substance Use, Trauma, Medication Adherence
- Trial name
- WE RISE (NCT06216600)
- Testing
- Acceptance and Commitment Therapy (ACT), Body weight circuit training, Empathetic social support
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anxiety Depression (Mild or Not Persistent)
Implementation and Evaluation of an Internet-Based Stress Management Program for Health Students in the Sfax Region
The objective of this experimental study (randomized controlled trial) is to evaluate the effectiveness of an internet-based stress management program, inspired by the French program "Je gère mon stress," among healthcare…
- Trial name
- NCT07123311
- Testing
- Online Stress Management Program
- Where
- Tunisia
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Sfax
Human Immunodeficiency Virus, Cardiometabolic Risk
The Happy Older Latinos Are Active (HOLA) Health Promotion Study in HIV-Infected Latino Men
The purpose of this study is to examine the feasibility of an intervention to prevent chronic diseases like diabetes, high blood pressure, and obesity in midlife and older Latino adults living with HIV.
- Trial name
- HOLAHIV (NCT03839212)
- Testing
- HOLA Component 1, HOLA Component 2, HOLA Component 3
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Cardiovascular Disease, Hematologic Diseases
Gulf Long-Term Follow-Up Study
Background: There has been little research on the long-term health effects from oil spills, even though at least 10 percent of all oil tanker spills between 1970 and 2009 have affected coastal populations.
- Conditions
- Cardiovascular Disease, Hematologic Diseases, Immunologic Disease, Cancer
- Trial name
- NCT01287000
- Where
- United States
- Volunteers
- 32,658 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Dating Violence, HIV Infections
Dating Violence and HIV Prevention in Girls: Adapting Mental Health Interventions
This project is designed to develop and test a group-based preventive intervention to reduce dating violence and sexual risk behavior among adolescent females with prior dating violence exposure.
- Trial name
- NCT01326195
- Testing
- Cognitive-Behavioral Dating Violence and HIV Prevention Group, Psycho-educational Dating Violence and HIV prevention group
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Asthma
The Study of Single Dose Administration of GR2002 Injection in Chinese Health Volunteers
To evaluate the pharmacokinetic (PK) characteristics and pharmacological effect of GR2002 injection in Chinese healthy volunteers
- Trial name
- NCT05954611
- Testing
- GR2002 injection
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Genrix (Shanghai) Biopharmaceutical Co., Ltd.
HIV/AIDS, Sexually Transmitted Infection
GPS: Adaptation Trial of an HIV Prevention Counselling Program for HIV-positive and HIV-negative Gay and Bisexual Men
GPS is a sexual health promotion and HIV prevention peer-delivered counselling program. The GPS program has 4 parts: information provision about HIV and sexually transmitted infections, motivational interviewing counselling…
- Conditions
- HIV/AIDS, Sexually Transmitted Infection, Health Behavior
- Trial name
- NCT03186183
- Testing
- GPS program
- Where
- 6 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Toronto Metropolitan University
Hypertension, Substance Abuse
Linking Former Inmates to Primary Care
The Transitions Clinic Network (TCN)aims to connect former inmates to primary care using trained, culturally competent primary care providers and community health workers (CHWs).
- Conditions
- Hypertension, Substance Abuse, Asthma, Depression
- Trial name
- NCT01863290
- Testing
- Primary care redesign
- Where
- 11 sites in United States, Puerto Rico
- Volunteers
- 816 people
- Sponsor
- Yale University
Pediatric ALL
Quality of Life for Pediatric Urolithiasis
The aim of this study is to assess the quality of life (QoL) in pediatric patients with urinary stone disease.
- Trial name
- Elattar (NCT06092203)
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Type 1 Diabetes (T1D), Glycemic Control for Diabetes Mellitus
Evaluation of a Novel Insulin Sensitizer in People With Type 1 Diabetes
The purpose of this study is to see if the study drug CIR-0602K will improve glucose time-in-range and/or lower total daily insulin dose in people with type 1 diabetes who are using closed-loop automated insulin delivery.
- Conditions
- Type 1 Diabetes (T1D), Glycemic Control for Diabetes Mellitus, Insulin, Ketones
- Trial name
- WBH003 (NCT07186660)
- Testing
- CIR-0602K
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia
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