Clinical trials: Immune Health
General Population
Effects of Vital Shower on Quality of Life, Immune Function, Cardiovascular Regulation and Well-being
The aim of this exploratory randomized controlled clinical study is to evaluate the health-promoting effects of Kneipp hydrotherapy, in the form of the Vital Shower in a four-week daily application.
- Trial name
- NCT05328856
- Testing
- Hansgrohe prototype/shower head
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Suicide, Suicidal Ideation
Telehealth to Reduce Suicidality and Improve HIV Care Engagement in Tanzania
The overall objectives of the proposed research are to develop a brief telehealth counseling intervention to provide support for people living with HIV and experiencing suicidal ideation, and to support HIV care engagement.
- Conditions
- Suicide, Suicidal Ideation, HIV Infections, Adherence, Medication
- Trial name
- NCT04696861
- Testing
- IDEAS for Hope, Enhanced Standard of Care (Safety Planning)
- Where
- 2 sites in Tanzania
- Volunteers
- 60 people
- Sponsor
- Duke University
Asthma
Comparing Asthma Action Plans for Pediatric Asthma
The purpose of this study is to evaluate and compare the relative effectiveness of two asthma action plans (pictorial versus written) in terms of asthma action plan knowledge, medication use, and family satisfaction with asthma…
- Trial name
- NCT00136305
- Testing
- Pictorial asthma action plan, Written asthma action plan
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Children's Mercy Hospital Kansas City
Asthma
The Role of Vitamins E and C in Maintaining Lung Health in People With Asthma
This study will determine if airway antioxidant levels in allergic asthmatics are enhanced with a combination of vitamin E and vitamin C therapy.
- Trial name
- VITAS (NCT00142610)
- Testing
- Vitamin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of North Carolina, Chapel Hill
Healthy
Galactooligosaccharide, Immune Strength, and Digestive Health in Older Adults Over Cold and Flu Season
The purpose of this research study is to determine whether a functional fiber, galactooligosaccharide, can help maintain immune strength and digestive health in free-living older adults.
- Trial name
- GOS (NCT01302561)
- Testing
- Sucrose, Galactooligosaccharide
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Florida
Asthma
Rural Asthma Effectiveness Study
The investigators will test if their intervention, Asthma Self-Management for Adolescents (ASMA), an 8-week, high school-based intervention for teenagers, improves asthma in rural high school students with uncontrolled asthma…
- Trial name
- NCT03533764
- Testing
- ASMA
- Where
- United States
- Volunteers
- 359 people
- Sponsor
- Columbia University
Respiratory Tract Infections (RTI), Mucosal Immunity
Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before and After a Race
This study aims to evaluate whether a fermented milk drink containing the probiotic strain Lacticaseibacillus paracasei strain Shirota (LCS), commonly found in Yakult®, can help reduce upper respiratory symptoms in triathletes…
- Conditions
- Respiratory Tract Infections (RTI), Mucosal Immunity, Systemic Inflammation, Depressive Disorder
- Trial name
- NCT06970964
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
HIV Infections, Breast Cancer
The MARVIN Chatbots to Provide Information for Different Health Conditions
This research is a continuation of a usability study with the MARVIN chatbot. The investigators aim to adapt the MARVIN chatbot to open it to other health domains (e.g. breast cancer) and populations (e.g. pharmacists).
- Conditions
- HIV Infections, Breast Cancer, Pediatric Emergency Medicine
- Trial name
- NCT05789901
- Testing
- MARVIN, MARVIN-Pharma, MARVINA
- Where
- 2 sites in Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
HIV Infections
A Study of Two Adherence Plans to Help HIV-Positive Patients Take Their Medications Correctly
The purpose of this study is to look at different ways to help patients follow their anti-HIV medication schedules. It is very important that HIV-positive patients take their anti-HIV medications correctly so they get the best…
- Trial name
- NCT00001129
- Testing
- Electronic Medication Reminder System, Medication Manager
- Where
- 20 sites in United States
- Volunteers
- 1,248 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hodgkin Lymphoma, Non-Hodgkin Lymphoma
Telehealth Exercise Intervention to Improve Cardiovascular Health in Lymphoma Survivors, TECHS Trial
This clinical trial tests how well a telehealth exercise intervention works to improve cardiovascular health in lymphoma survivors.
- Trial name
- NCT05205512
- Testing
- Exercise Intervention, Questionnaire Administration, Telemedicine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- City of Hope Medical Center
Lymphoma, Non-Hodgkin
Chronic and Late Effects of Non-Hodgkin's Lymphoma and Its Treatment in Long Term Survivors
Non-Hodgkin's lymphoma has been studied in the Pediatric Branch for at least 20 years, during which time a number of different treatment protocols have been used.
- Trial name
- NCT00001301
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- National Cancer Institute (NCI)
Diabetes Mellitus, Type 1, Child
Breaking Disparities in Access to Advanced Diabetes Technologies in Children With Type 1 Diabetes
50 children/adolescents (ages 6 to <18yrs) with T1D in suboptimal control (HbA1c≥8.0%) and lower SES (below 200% poverty line) on insulin therapy (either injections or open-loop pumps) will be recruited at Nemours ~ 1/3 each AA…
- Conditions
- Diabetes Mellitus, Type 1, Child, Delivery of Health Care, Equipment and Supplies
- Trial name
- NCT05849753
- Testing
- Advanced artificial pancreas closed-loop technology
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Nemours Children's Clinic
HIV/AIDS
Developing and Examining Evidenced-Based HIV Testing Messages
The goals of this study are to: 1. Develop a HIV test message tailored for African American women. A generic non-tailored message will be developed as well for comparison.
- Trial name
- NCT03433053
- Testing
- HIV Testing Message Intervention, Control
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Kidney Diseases, Chronic Kidney Diseases
NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities
The overarching goal of this project is to refine and adapt previous work on the NAVIGATE-Kidney project for individuals with CKD.
- Trial name
- NAV-Kidney (NCT06810622)
- Testing
- Community health worker intervention, Standard Care (in control arm)
- Where
- 2 sites in United States
- Volunteers
- 448 people
- Sponsor
- University of Colorado, Denver
Juvenile Idiopathic Arthritis
Oral Health, Saliva Bacteria, and Disease Activity in Children With JIA: A Cross-Sectional Study.
The goal of this observational study is to learn about the relationship between disease activity and oral health status in children with juvenile idiopathic arthritis (JIA).
- Trial name
- JIA (NCT07799831)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
HIV, Mental Health
Social Contact-Based Brief Video Interventions To Reduce Stigma and ImproVe Engagement in HIV Prevention and Care and Mental Health Care for Youth Living With and Vulnerable to HIV
HIV stigma, poverty, and racism contribute to high rates of mental health problems and impede treatment for young sexually minoritized men living with and vulnerable to HIV.
- Trial name
- STRIVE (NCT07851077)
- Testing
- Brief Videos for HIV Stigma
- Volunteers
- 3,900 people, healthy volunteers welcome
- Sponsor
- City University of New York, School of Public Health
Diabetes, Hypertension
Exploring Folk Health Practices in Latinos With Chronic Medical Conditions
This study will explore how culture influences the use of folk healing practices and medical services in Latinos with chronic medical conditions.
- Conditions
- Diabetes, Hypertension, Asthma, Heart Disease
- Trial name
- NCT00224237
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Weill Medical College of Cornell University
Asthma, Pediatric ALL
Registry and Screening Tool to Identify Children With Asthma Likely to Benefit From Home Assessment and Remediation
Recognizing a decline in pediatric primary care visits and immunizations rates, an increase in utilization of the emergency room and stagnating academic achievement, leaders of MetroHealth Medical Center and the Cleveland…
- Conditions
- Asthma, Pediatric ALL, School Health Services, Registries
- Trial name
- CREST (NCT03916237)
- Testing
- Home assessment, Home remediation, Referral to Medical Legal Partnership
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- MetroHealth Medical Center
Depression, HIV Infection
Suubi-Mhealth: A Mobile Health Intervention to Address Depression Among Youth
The overall goal of this study is to develop an mHealth intervention (Suubi-Mhealth) for use among Ugandan youth (14-17 years) with comorbid HIV and depression, taking into account their unique contextual, cultural, and…
- Trial name
- NCT05965245
- Testing
- Suubi-Mhealth
- Where
- 2 sites in United States, Uganda
- Volunteers
- 248 people
- Sponsor
- Washington University School of Medicine
Cancer
Development and Validation of a Health-related Quality of Life Instrument
This study aims to develop a health related quality of life (HRQOL) patient reported outcome (PRO) for patients receiving immune checkpoint modulator (ICM) therapy.
- Trial name
- FACT-ICM (NCT02651831)
- Testing
- Focus groups and individual interviews, Questionnaire
- Where
- Canada
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
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