Clinical trials: Immune System Disease
Multiple Sclerosis, Relapsing-Remitting, Healthy Controls
The Relationships Between Personal Identity, Autobiographical Memory and Future Thinking in People With Multiple Sclerosis
Personal identity is composed of multiple facets of the self that are constructed and nourished through memories of past experiences (i.e., autobiographical memory) and the imagination of events that may occur in the future…
- Trial name
- SELFSEP (NCT05648292)
- Testing
- Neuropsychological tests and psychological questionnaires
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Chronic Urticaria
Stress Intervention for Chronic Urticaria
Stress and chronic urticaria has been linked. The purpose of the study is to evaluate a patients chronic urticaria and stress levels before and after he/she goes through six sessions designed to help that participant manage…
- Trial name
- NCT01111136
- Testing
- Stress intervention
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Mississippi Medical Center
HIV Infections, Acquired Immunodeficiency Syndrome
Efficacy of Thrice Weekly Directly Observed Treatment, Short-course (DOTS) in HIV-associated Tuberculosis
Tuberculosis (TB) is the most common opportunistic infection among HIV infected persons living in developing countries. Directly observed treatment, short-course (DOTS) is the internationally recommended strategy for the…
- Conditions
- HIV Infections, Acquired Immunodeficiency Syndrome, Tuberculosis
- Trial name
- NCT00698334
- Testing
- INH, Rifampicin, Ethambutol and Pyrazinamide
- Where
- India
- Volunteers
- 150 people
- Sponsor
- All India Institute of Medical Sciences
Nonspecific Chronic Low Back Pain
Effectiveness of the Addition of the Kinesio Taping Method to Conventional Physical Therapy Treatment in Patients With Chronic Nonspecific Low Back Pain
The purpose of this study is to determine the effectiveness of the addition of the use of Kinesio Taping in patients with chronic nonspecific low back pain who receive conventional physical therapy.
- Trial name
- NCT01866332
- Testing
- Conventional Physical Therapy, Kinesio Tex Gold ( Kinesiotaping )
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- Universidade Cidade de Sao Paulo
HIV Infections, Hepatitis B
Project UNITY - HIV Risk Reduction and Vaccine Education Interventions
To determine the efficacy of an enhanced HIV risk reduction intervention delivered concurrently with a vaccination schedule to reduce the number of unprotected vaginal and anal sex acts among HIV-negative, high-risk non-injection…
- Trial name
- NCT00150098
- Testing
- Enhanced HIV risk reduction and HIV vaccine education
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- New York Blood Center
Asthma
Impact of a Hospital Pharmacist's Intervention on FENO (Fractional Exhaled Nitric Oxide) in Asthmatic Patients
The impact of a pharmacist's intervention on asthma control has now been well demonstrated, but its effect on inflammatory markers of FENO (Fractional exhaled nitric oxide) in asthmatic patients has been little studied in the…
- Trial name
- NCT03093363
- Testing
- Pharmacist's intervention, Questionnaires for control group
- Volunteers
- 68 people
- Sponsor
- University of Liege
HIV-1, HIV Infections
Genotypic Resistant HIV Strains in Taiwan
Based on the investigators previous study, seventy-four of 786 HIV-1 isolates (9.4%), collected between 1999 to 2006, harbored one or more primary mutations associated with antiretroviral resistance to reverse-transcriptase…
- Trial name
- NCT00954863
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Multiple Myeloma
GMMG-HD11/DSMM XXI/64007957MMY3010
This is an open-label, randomized interventional multicenter Phase 3 clinical trial to investigate the efficacy and safety of Tec-DRd induction therapy and fixed-duration Tec-D maintenance post ASCT in adult participants with TE…
- Trial name
- AugMMent (NCT07671287)
- Testing
- Teclistamab, Daratumumab, Lenalidomide
- Volunteers
- 399 people
- Sponsor
- University of Heidelberg Medical Center
Adult Onset Still Disease
Multi-center Registration Study of Adult Onset Still's Disease in Chinese Population
This multi-center registration study will investigate the clinical characteristics of AOSD population in China , identify possible factors inducing the onset and active condition of AOSD in Chinese population , and identify the…
- Trial name
- MAOSDC (NCT03651193)
- Testing
- Exon sequencing and Methylated sequencing
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Second Xiangya Hospital of Central South University
Multiple Myeloma
Finistere Myeloma Observatory (OMYFIN)
Current molecular risk stratification of multiple myeloma (MM), based on the presence of t(4 ;14) and 17p deletion, cannot fully explain treatment outcome heterogeneity, as other features also predict prognosis.
- Trial name
- OMYFIN (NCT06552221)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Lymphoma
Autologous and Allogenic Transplantation With Campath-1H for T-Cell Lymphoma
Primary Objectives: 1. To evaluate the role of autologous and allogenic stem cell transplantation with Campath-1H for patients with peripheral T-cell lymphoma (PTCL). 2.
- Trial name
- NCT00505921
- Testing
- Campath-1H, G-CSF, GM-CSF
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- M.D. Anderson Cancer Center
Respiratory Diseases, Neurological Disorders
Exhaled Breath Analysis by Secondary Electrospray Ionization - Mass Spectrometry in Children and Adolescents
This study is to investigate breath analysis (breath metabolomics) combined with established bioinformatic tools as a platform for companion diagnostics.
- Conditions
- Respiratory Diseases, Neurological Disorders, Type 1 Diabetes
- Trial name
- EBECA (NCT04461821)
- Testing
- Real-time SESI-MS breath analysis, Off-line breath analysis, Blood analysis
- Where
- Switzerland
- Volunteers
- 3,600 people
- Sponsor
- University Children's Hospital Basel
Multiple Sclerosis
Can Transcranial Direct Current Stimulation Improve Ambulation and Fatigue Resistance in People With MS?
In this project the investigators will be using non-invasive brain stimulation on people with multiple sclerosis (PwMS) to improve leg muscle function. Two groups of participants will be recruited.
- Trial name
- NCT02987621
- Testing
- tDCS
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Colorado State University
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
The main purpose of this study is to evaluate the safety and efficacy of nipocalimab compared to placebo in delaying relapse in adults with chronic inflammatory demyelinating polyneuropathy (CIDP) who initially respond to…
- Trial name
- NCT05327114
- Testing
- Nipocalimab
- Where
- 120 sites in United States, Argentina and 17 more
- Volunteers
- 201 people
- Sponsor
- Janssen Research & Development, LLC
Type 1 Diabetes
Washed Microbiota Transplantation for Type 1 Diabetes Mellitus
This is a real-world study to explore the safety and the efficacy of washed microbiota transplantation (WMT) for patients with Type 1 Diabetes Mellitus (T1DM).
- Trial name
- NCT06256614
- Testing
- WMT
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Second Hospital of Nanjing Medical University
HIV, Seroconversion, HIV
Accurate Staging of Immuno-virological Dynamics During Acute HIV Infection
In this prospective longitudinal study we aim to assess how immunologic and viral aspects of the human immunodeficiency virus (HIV) viral reservoir, established during early HIV infection and responsible for viral rebound at…
- Trial name
- ACS (NCT03449706)
- Testing
- Early combination anti-retroviral treatment
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Atopic Dermatitis
Study of Dupilumab in Adult Patients With Extrinsic Moderate-to-Severe Atopic Dermatitis
The primary objective was to assess the clinical efficacy of repeated subcutaneous (SC) doses of Dupilumab in adult participants with moderate-to-severe atopic dermatitis (AD).
- Trial name
- NCT01548404
- Testing
- Dupilumab
- Where
- 21 sites in Czechia, France and 3 more
- Volunteers
- 109 people
- Sponsor
- Regeneron Pharmaceuticals
Atopic Dermatitis
Efficacy Study of Montelukast in Atopic Dermatitis Induced by Food Allergens
AD is a disease found in children; the focus of the study is the mechanisms associated in children with AD induced by food allergies.
- Trial name
- NCT00557284
- Testing
- Montelukast
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- 1st Allergy & Clinical Research Center
Avascular Necrosis, Osteoarthritis
Zimmer Continuum Metal on Polyethylene (MoP) PostMarket Clinical Followup (PMCF) Study
This is a prospective, multi-center, non-randomized, non-controlled study designed to obtain survival and outcome data on the Continuum Metal on Polyethylene Acetabular System when used in primary total hip arthroplasty.
- Conditions
- Avascular Necrosis, Osteoarthritis, Inflammatory Arthritis, Post-traumatic Arthritis
- Trial name
- NCT01307384
- Testing
- Continuum Metal on Polyethylene Acetabular System
- Where
- 2 sites in United States
- Volunteers
- 195 people
- Sponsor
- Zimmer Biomet
Multiple Myeloma
PF-06863135 As Single Agent And In Combination With Immunomodulatory Agents In Relapse/Refractory Multiple Myeloma
To assess the safety and tolerability at increasing dose levels of PF-06863135 in patients with relapse/ refractory multiple myeloma in order to determine the maximum tolerated dose and select the recommended Phase 2 dose.
- Trial name
- NCT03269136
- Testing
- PF-06863135 monotherapy IV or SC, PF-06863135 + dexamethasone, PF-06863135 + lenalidomide
- Where
- 37 sites in United States, Canada
- Volunteers
- 101 people
- Sponsor
- Pfizer
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