Clinical trials: Immunonutrition
Pancreatic Tumor, Bile Duct Tumor
Additional Effects of Perioperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy
The purpose of this study is to investigate whether perioperative immunonutrition has additional effects on cell-mediated immunity in patients undergoing pancreaticoduodenectomy.
- Trial name
- NCT01969110
- Testing
- Oral IMPACT
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Chiba University
Gastrointestinal Cancer
Effects of 3 Day Preoperative Immunonutrition in Well-nourished Patients With Gastrointestinal (GI) Cancer Undergoing Surgery
Major surgery is still associated with a high rate of postoperative morbidity despite improved techniques in surgical management.
- Trial name
- IPOD-3 (NCT01023412)
- Testing
- Immunonutrition
- Where
- 6 sites in Switzerland
- Volunteers
- 107 people
- Sponsor
- Société des Produits Nestlé (SPN)
Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer
GALENOS 1 in Head and Neck, Lung, and Rectal Cancer Patients
GALENOS 1 is a prospective observational study designed to explore longitudinal changes in nutritional status and body composition in patients with head and neck squamous cell carcinoma, locally advanced rectal cancer, and lung…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer, Lung Cancer
- Trial name
- GALENOS 1 (NCT07511413)
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Gastric Cancer, Colorectal Cancer
"The Impact of Immunonutrition on Gut Microbiota-related Aspects in Colorectal Cancer and Gastric Cancer Patients"
Enteral immunomodulating nutrition modifies the gastrointestinal microbiota as well as improves the intestinal barrier integrity in patients with gastric and colorectal cancer in the perioperative period.
- Trial name
- NCT04980950
- Testing
- Impact Oral Nestlé Health Science, Cubitan® Nutricia, Nutridrink® Nutricia, Resource 2.0 Nestlé Health Science
- Volunteers
- 80 people
- Sponsor
- Medical University of Gdansk
Colorectal Adenocarcinoma
ImmunoNutrition and Colorectal Adenocarcinoma Surgery - INCAS Study
Compared to upper gastrointestinal (GI) malignancies, CRC patients generally present with satisfactory nutritional status at surgery and malnutrition is typically present in advanced stages of CRC.
- Trial name
- INCAS (NCT06134440)
- Testing
- Impact Oral®
- Where
- Italy
- Volunteers
- 71 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Nutritional Deficiency, Gynecologic Cancer
Immunonutrition in ERAS Protocols in Gynecologic Oncology
A patient with oncological pathology of any type because of impaired digestion and nutrient absorption, decreased intake, and increased nutrition requirements has an increased risk of malnutrition and moderate to severe weight…
- Conditions
- Nutritional Deficiency, Gynecologic Cancer, ERAS
- Trial name
- NUTRIGO (NCT06103526)
- Testing
- Immunonutrition
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Gastrointestinal Tumors, Immunonutrition
Effects of Immunonutrition on the Improvement of Postoperative Adjuvant Chemotherapy Related Adverse Reactions in Patients With Gastrointestinal Tumors
Evaluate the effects of Suyusu (immunonutrition) in postoperative adjuvant chemotherapy for gastrointestinal cancer patients. The main endpoint of the study was the incidence of chemotherapy related adverse reactions (including…
- Conditions
- Gastrointestinal Tumors, Immunonutrition, Postoperative Adjuvant Chemotherapy
- Trial name
- NCT06085365
- Testing
- Immunonutrition （Su yusu), fluorouracil based chemotherapy regimens
- Where
- China
- Volunteers
- 324 people
- Sponsor
- China Medical University, China
Postoperative Complications
Effect of Immunonutrition on Inflamatory Markers After Bariatric Surgery
A prospective randomized clinical trial of all the patients undergoing Roux - en-Y gastric bypass will be performed. Patients will be randomly assigned into 2 groups: those patients receiving a preoperative balanced energy…
- Trial name
- NCT03010280
- Testing
- Immunonutrition, Balanced high-protein formula
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Cystic Fibrosis, Malnutrition
Impact of Immunonutrition on the Patients With Cystic Fibrosis
The primary objectives: To evaluate the effect of immunonutrition on the adult patient suffering from cystic fibrosis 1. Safety of immunonutrition 2. The effect of immunonutrition on parameters of oxidative stress 3.
- Conditions
- Cystic Fibrosis, Malnutrition, Oxidative Stress
- Trial name
- NCT02048592
- Testing
- Impact-Nutridrink, Nutridrink-Impact
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- University Hospital, Motol
Cardiac Function
Preoperative Immunonutrition and Cardiac Patients
With the progress of cardiac surgery, the indication of cardiac valve replacement has been extended to include severely ill patients, even those with cardiac cachexia caused by long-standing mitral valve disease.
- Trial name
- NCT03445221
- Testing
- IV Immunonutrition, Conventional Diet
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Esophageal Neoplasms
Effects of Preoperative Enteral Immunonutrition for Esophageal Cancer Patients Given Neoadjuvant Chemoradiotherapy
This randomized controlled trial will evaluate the effects of preoperative enteral immunonutrition in esophageal cancer patients undergoing neoadjuvant therapy.
- Trial name
- POINT (NCT04513418)
- Testing
- Preoperative immunonutrition
- Where
- 6 sites in China
- Volunteers
- 244 people
- Sponsor
- Hecheng Li M.D., Ph.D
Sepsis, Septic Shock
ICITRU : Randomized Trial of Immunonutrition With L-citrulline in Patients Hospitalized in Intensive Care for Sepsis or Septic Shock
Immunonutrition in intensive care has not yet demonstrated a beneficial effect on organ failure, the acquisition of nosocomial infections, or mortality.
- Trial name
- ICITRU (NCT04513288)
- Testing
- Experimental treatment L-citrulline (Protéocit®)
- Where
- 5 sites in France
- Volunteers
- 130 people
- Sponsor
- Rennes University Hospital
Bile Duct Cancer
Effects of Preoperative Immunonutrition in Patients Undergoing Hepatectomy
The purpose of this study is to determine whether preoperative immunonutrition is effective on infectious complication and Th1/Th2 differentiation in patients with major hepatectomy.
- Trial name
- NCT01256047
- Testing
- Oral IMPACT
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Chiba University
Diabetes Mellitus, Diabetic Peripheral Neuropathy
Immunonutrition for Diabetic Foot Ulcers
Diabetes-induced peripheral neuropathy can lead to the development of diabetic foot ulcers (DFUs), which can have a devastating effect on patients' lives and can lead to life threatening infection, amputations, and even death.
- Conditions
- Diabetes Mellitus, Diabetic Peripheral Neuropathy, Diabetic Foot Ulcer
- Trial name
- NCT05281562
- Testing
- Lovaza, L-Arginine Powder, Vitamin C
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Prisma Health-Midlands
Head and Neck Cancer, Infection
Study of Nutrition Regimens in Treating Patients With Cancer of the Upper Aerodigestive Tract
RATIONALE: It is not yet known which regimen of enteral nutrition is more effective in preventing infections in patients undergoing surgery for cancer of the upper aerodigestive tract.
- Conditions
- Head and Neck Cancer, Infection, Malnutrition
- Trial name
- NCT00765440
- Testing
- therapeutic nutritional supplementation
- Where
- France
- Volunteers
- 311 people
- Sponsor
- Centre Antoine Lacassagne
Wound Complication, Wound Heal
Immunonutrition and Carbohydrate Loading Strategies in Breast Reconstruction
This study is designed to test the following hypothesis: patients undergoing immediate alloplastic and autologous breast reconstruction following mastectomy that receive preoperative immunonutrition will experience a reduction in…
- Conditions
- Wound Complication, Wound Heal, Complications Wound, Surgical Wound Infection
- Trial name
- NCT03764943
- Testing
- Impact Advanced Recovery
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Wisconsin, Madison
Gastrointestinal Cancer
Immunonutrition and Quality of Life of Cancer Patients Undergoing Oncological Treatment
The purpose of this study is to compare the health-related quality of life following dietary supplementation with an immunonutrition formulation vs an isocaloric/isoprotein control diet supplement in patients suffering from upper…
- Trial name
- Neoimmune (NCT01423799)
- Testing
- Nutritional supplements containing arginine, n-3 and nucleotides, Isocaloric control
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Société des Produits Nestlé (SPN)
Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer
Galenos 2 Immunonutrition in Head and Neck, Lung, and Rectal Cancer Patients
GALENOS 2 is a single-arm, single-center, phase II interventional study designed to evaluate the effects of a galenic immunonutrition dietary supplement in patients with head and neck squamous cell carcinoma, locally advanced…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer, Lung Cancer
- Trial name
- GALENOS 2 (NCT07514754)
- Testing
- Galenic Immunonutrition Formula
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Major Abdominal Surgery
Immunonutrition Versus Standard Enteral Nutrition Before Major Surgery
The aim of this trial is to compare preoperative Imunnonutrition with standard enteral nutrition regarding morbidity after major abdominal surgery in patients with NRS greater 3.
- Trial name
- NCT00512213
- Testing
- Immunonutrition for 5 days preoperative, Standard enteral nutrition for 5 days preoperative
- Where
- Switzerland
- Volunteers
- 154 people
- Sponsor
- University of Lausanne Hospitals
Colorectal Cancer
Preoperative Immunonutrition in Normonourished Patients Undergoing Fast-track Laparoscopic Colorectal Surgery
Immunonutrition (IN) appears to reduce infective complications and in-hospital length of stay (LOS) after gastrointestinal surgery. More specifically, it seems to be beneficial also in colorectal cancer surgery.
- Trial name
- NCT04692545
- Testing
- Immunonutrition
- Volunteers
- 173 people
- Sponsor
- University of Rome Tor Vergata