Clinical trials: Immunosenescence
Cancer Survivors, Healthy Participant
A Study to Evaluate the Effects of the Combination of GI-102 With GIB-7 on Biomarkers of Aging in Healthy Adults and Cancer Survivors
This Phase 2a clinical study (GIANTS-1) aims to evaluate a novel dual-combination strategy using GI-102 and GIB-7 to address key pathological features of aging, including immunosenescence (the aging of the immune system)…
- Conditions
- Cancer Survivors, Healthy Participant, Elderly
- Trial name
- GIANTS-1 (NCT07363057)
- Testing
- GI-102 in combination with GIB-7
- Where
- 2 sites in Australia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- GI Innovation, Inc.
Alzheimer Disease, Late Onset
BCG and Plasma Amyloid in Non-Demented Adults
BCG vaccination, the most widely used vaccination in the world, is used to reduce risk of tuberculosis infection; it is used for other mycobacterial infections as well, benefiting leprosy and Buruli ulcer.
- Trial name
- NCT04449926
- Testing
- Bacillus of Calmette and Guerin (BCG)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Mindful Diagnostics and Therapeutics, LLC
Clinically Symptomatic Respiratory Illness
Effect of RTB101 on Illness Associated With Respiratory Tract Infections in the Elderly
The purpose of this study is to determine if RTB101 prevents illness associated with respiratory tract infections in people ≥65 years of age.
- Trial name
- NCT04139915
- Testing
- Dactolisib
- Sponsor
- Restorbio Inc.
Chronic Inflammation, Inflammaging
2021 PMT iAge® Intervention Trial by Edifice Health
This is a decentralized, double-blind, randomized, placebo-controlled study to assess the effectiveness of different dietary supplements in decreasing systemic chronic inflammation (SCI) and lowering inflammatory age (iAge®).
- Trial name
- NCT04983017
- Testing
- Dietary supplement
- Where
- 2 sites in United States
- Volunteers
- 781 people, healthy volunteers welcome
- Sponsor
- Edifice Health
Epigenetic Aging, Immunosenescence
Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial
The TRIIM-X trial is an expanded pilot clinical study that will evaluate a personalized combination treatment regimen for thymus regeneration.
- Trial name
- TRIIM-X (NCT04375657)
- Testing
- TRIIM Treatment, Active Control
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Intervene Immune, Inc.
Immune Deficiency
Efficacy of QBKPN Site-Specific Immunomodulator in Improving Innate Immune Function & Reducing Respiratory Tract Infection in Older Adults
This study is designed to test whether QBKPN SSI can improve immune function in older adults, including how well it can protect against respiratory and other infections, whether it improves the body's response to COVID-19…
- Trial name
- RESILIENCE (NCT05421325)
- Testing
- QBKPN SSI
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Qu Biologics Inc.
Immunosenescence
The Effect of Prebiotic B-GOS on the Immune Function, Metabolism and Gut Microbiota of Elderly People
The purpose of this study is to determine the effects of prebiotic B-GOS on the immune function, metabolism and gut microbiota of elderly people
- Trial name
- PRIMES (NCT01303484)
- Testing
- Bi2muno® GOS, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clasado
Healthy
Effect of TA-65MD on Healthy Volunteers
TA-65 MD® is pure, natural, plant-based compound that can help maintain or rebuild telomeres. A telomere is a region of repetitive DNA at the end of a chromosome, which protects the end of the chromosome from deterioration.
- Trial name
- TA-65MD (NCT02766790)
- Testing
- TA-65MD
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Telomerase Activation Sciences, Inc
Immunity Disorders, Aging
The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age
This is a prospective, interventional, single-arm, open-label pilot study of 50 patients to evaluate the effect of a polyphenol-rich nutritional supplement on epigenetic and cellular markers of immune age.
- Conditions
- Immunity Disorders, Aging, Inflammation
- Trial name
- NCT05234203
- Testing
- HTB Rejuvenate
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Big Bold Health, PBC