Clinical trials: Impact on Patients
Diabetes Mellitus Type 2
A Clinical Trial Assessing The Impact Of Inhaled Insulin On Glucose Control In Patients With Type 2 Diabetes Mellitus
To assess the impact on glucose control by inhaled insulin in patients with type 2 diabetes who are not well controlled on 2 or more oral anti-diabetic agents
- Trial name
- NCT00282971
- Testing
- Inhaled Insulin (Exubera), Standard of Care
- Where
- 64 sites in Canada, France and 5 more
- Volunteers
- 354 people
- Sponsor
- Pfizer
Breast Cancer
Health-Related Quality of Life Coupled With Therapeutic Information on Compliance to Endocrine Therapy in Breast Cancer
Only 59% of women with breast cancer (BC) treated with Endocrine Therapy (ET) remain compliant one year upon initial prescription, despite its proven effectiveness in reducing recurrence and improving survival.
- Trial name
- COMPLIANCE (NCT04176809)
- Testing
- Routine Assessment of HRQoL coupled with Therapeutic Information
- Where
- France
- Volunteers
- 342 people
- Sponsor
- Centre Georges Francois Leclerc
Heart Failure, Transplant; Failure, Heart
Exercise-based Cardiac Rehabilitation Program on Hospitalized Heart Failure Patients Submitted to Cardiac Transplantation
Objective: To evaluate the effects of an early-based cardiac rehabilitation program on the functional capacity, inspiratory muscular strength and clinical outcomes in hospitalized heart failure patients before and after heart…
- Conditions
- Heart Failure, Transplant; Failure, Heart, Physical Activity
- Trial name
- NCT03506737
- Testing
- Conventional exercise protocol, Cycle ergometer exercise protocol
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Nasopharyngeal Cancinoma (NPC)
Impact of Vitamin D on Therapeutic Respons in NPC Chemoradiated Patients
Nasopharyngeal cancer is the sixth most common cancer and the sixth leading cause of death in Indonesia. NPC is a radiosensitive cancer so radiotherapy is the basic therapy for NPC.
- Trial name
- NCT07042711
- Testing
- Vitamin D 5,000IU Oral Tablet
- Where
- Indonesia
- Volunteers
- 300 people
- Sponsor
- Universitas Indonesia
Gastroesophageal Reflux Disease, Morbid Obesity
Gastroesophageal Reflux Disease (GERD) Before and After Gastric Bypass
The hypothesis of this study was that gastric bypass (GBP) ameliorates gastroesophageal reflux disease (GERD) in morbidly obese patients.
- Trial name
- NCT00951093
- Testing
- Gastric bypass
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Clinica Gastrobese
Impact of SGLT2-inhibitors on PC-AKI in ACS Patients Receiving Invasive Strategy
SGLT2-inhibitors on PC-AKI
Percutaneous coronary intervention (PCI) is one of the most common invasive strategies employed in the diagnosis and treatment of coronary artery disease (CAD) patients.
- Trial name
- NCT06491953
- Testing
- SGLT-2 inhibitors
- Where
- China
- Volunteers
- 3,600 people
- Sponsor
- Shenyang Northern Hospital
Anorexia Nervosa
Assessment of the Impact of Early Treatment for Anorexia Nervosa in a Day Hospital on Food Symptomatology, the Outcome of Young Patients, and the Family Experience
During the management of chronic illnesses, the day hospital (DH) serves as a brief and effective alternative to traditional hospitalization, offering access to multidisciplinary care.
- Trial name
- EVA-FAM (NCT06218472)
- Testing
- Day Hospital Treatment, Multidisciplinary follow-up "as usual" within the service, Conduct semi-structured qualitative interviews
- Where
- France
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Laparoscopic Surgery, Positive End-Expiratory Pressure
Recruitment Maneuvers and PEEP-guided Electrical Impedance Tomography for Abdominal Laparoscopic Surgery Patients
Abdominal laparoscopy is widely utilized due to its benefits, including minimal invasiveness, improved cosmetic outcomes, and shorter hospital stays.
- Conditions
- Laparoscopic Surgery, Positive End-Expiratory Pressure, Electrical Impedance Tomography
- Trial name
- PEEP-EIT (NCT06850844)
- Testing
- electrical impedance tomography, Conventional Ventilation
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- Nguyen Dang Thu
Acute Heart Failure
Care Pathways of Acute Heart Failure Patients: Impact on In-hospital Mortality.
The investigators conducted a prospective observational study to describe the different pre-hospital and in-hospital pathways of patients with acute heart failure (AHF) and their association with in-hospital mortality.
- Trial name
- NCT03903198
- Volunteers
- 3,677 people
- Sponsor
- frederic ADNET
Chronic Heart Failure, Obstructive Sleep Apnea
CPAP and Physiotherapy for Heart Failure and Sleep Apnea in the Elderly
This study evaluates whether adding physiotherapy (including herbal medicine, acupuncture, and Tuina massage) to standard continuous positive airway pressure (CPAP) therapy can provide superior benefits compared to CPAP alone for…
- Trial name
- NCT07061171
- Testing
- Continuous Positive Airway Pressure, Herbal Decoction, Acupuncture
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Weihua Peng
Calcaneal Fractures
Sustentaculum Tali Screw Fixation Mode and Postoperative Foot-Ankle Function in Calcaneal Fractures
This is an observational, ambidirectional cohort study. Calcaneal fractures are the most common tarsal bone fractures, and most are intra-articular fractures involving the subtalar joint.
- Trial name
- NCT07822698
- Testing
- Screw Tip Position Relative to the Sustentaculum Tali
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Peking University Third Hospital
Rhabdomyolysis-Induced Renal Failure
Impact of Extrarenal Myoglobin Clearance on Renal Recovery in Patients With Severe Rhabdomyolysis
Severe rhabdomyolysis is a common medical emergency that can lead to acute kidney injury (AKI), sometimes requiring extracorporeal renal replacement therapy (ECRT).
- Trial name
- MYORHEIN (NCT07853677)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Elderly, Surgery
Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery
A majority of the elderly patients undergo surgery for malignant tumors. For these patients, postoperative tumor recurrence and metastasis are main factors that worsen long-term outcomes.
- Conditions
- Elderly, Surgery, Analgesia, Dexmedetomidine
- Trial name
- NCT03012971
- Testing
- Dexmedetomidine supplemented morphine analgesia, Morphine analgesia
- Where
- 12 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Peking University First Hospital
Hyperglycemia, Critically Ill Patients
Impact of 2 Blood Glucose Levels on Hospital Mortality in Patients Admitted in ICU
During hospitalization in the intensive care unit (ICU), the occurrence of a blood glucose imbalance is frequent and associated with increased mortality.
- Trial name
- INSUREA (NCT00591071)
- Testing
- Strict glycemic control, Conventional glycemic control
- Where
- 2 sites in France
- Volunteers
- 440 people
- Sponsor
- Poissy-Saint Germain Hospital
Cystic Fibrosis
Impact of Bronchial Drainage Technique by the Medical Device Simeox® on Respiratory Function and Symptoms in Adult Patients With Cystic Fibrosis
The main objective of the study is to evaluate the short-term effects of the airway clearance technique by the medical device Simeox (Physio Assist, France) versus Autogenic Drainage, on the pulmonary function of adult patients…
- Trial name
- MUCOSIM (NCT04010253)
- Testing
- SIMEOX, Autogenic drainage
- Where
- 8 sites in France
- Volunteers
- 31 people
- Sponsor
- Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche
Coronary Artery Disease (CAD), Cardiac Rehab
The Effect of Cardiac Rehabilitation on Ferroptosis in Patients With Coronary Artery Disease
Coronary artery disease (CAD) remains a major global health concern and is the leading cause of cardiovascular mortality worldwide.
- Conditions
- Coronary Artery Disease (CAD), Cardiac Rehab, Ferroptosis
- Trial name
- NCT07722637
- Testing
- Cardiac Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Diabetes Mellitus, Type 2
Impact of a Diabetes Transitions Tool Kit on Post-Hospitalization Glycemic Control
The goal of this research is to evaluate the impact and feasibility of using web-based patient-provider communication and a remote glucose monitoring tool to improve post-hospitalization glycemic control and patient self-care.
- Trial name
- DTTK (NCT01495975)
- Testing
- Diabetes Transitions Tool Kit
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Deborah Wexler, MD
Pelvic Floor Disorders
Does Using a 'Virtual Clinic' in Urogynaecology Improve Patient Experience and Reduce Cost?
The purpose of this study is to assess the impact of using a virtual clinic which combines a web-based interactive questionnaire (ePAQ-PF) used in advance of clinic appointments in combination with a telephone consultation has on…
- Trial name
- NCT02176330
- Testing
- ePAQ-PF followed by a telephone consultation., ePAQ-PF followed by a face to face consultation
- Where
- United Kingdom
- Volunteers
- 195 people
- Sponsor
- University of Sheffield
Nutrition Education, Enhanced Recovery After Surgery
Nutrition Education in Spine Surgery
The goal of this interventional study is to learn if having 15 minutes of surgery related nutrition education changes the food choices participants make during the time right before and after a spine surgery in participants who…
- Trial name
- NCT06719492
- Testing
- nutrition education
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Jennifer Bowden
Benign Prostatic Hyperplasia, Prostate Cancer
Impact of Anticoagulants and Antiplatelets in Patients on Transurethral Resection of the Prostate
Benign prostatic hyperplasia(BPH) is a common disease in urology among old men. If BPH symptom cannot be controlled by drugs, then transurethral resection of the prostate (TURP), is recommended.
- Trial name
- NCT02822963
- Where
- Taiwan
- Sponsor
- National Cheng-Kung University Hospital