Clinical trials: Impacted Mandibular Third Molar Extraction
Dental Anxiety, Impacted Third Molar Tooth
Anxiety Control by Erythrina Mulungu
This study evaluated the effectiveness of the Erythrina mulungu in controlling anxiety in patients undergoing bilateral extraction of asymptomatic, impacted mandibular third molars.
- Trial name
- NCT01948622
- Testing
- Mulungu
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liane Maciel de Almeida Souza
Molar, Third, Low-level Laser Therapy
"Effectiveness of Dual-Wavelength Laser Therapy in Third Molar Extraction Pain, Swelling, and Trismus"
Objective: To investigate the effects of single session dual wavelength low dose laser therapy to be applied after third molar tooth extraction on postoperative pain, edema and physical activities.
- Trial name
- NCT05992233
- Testing
- Dual wavelength low level laser
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Alveolar Bone Loss
Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation
This study is designed to evaluate and compare clinically and radiographically the effectiveness of Demineralized Dentin Allograft (DDA) versus Demineralized Dentin Autograft (Auto-DD) for preservation of alveolar ridge…
- Trial name
- NCT06457373
- Testing
- Demineralized Dentin Allograft, Demineralized Dentin Autograft
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Horus University
Impacted Mandibular Third Molar Extraction, Post Operative Complications
A Comparison of Recovery After Impacted Wisdom Tooth Removal
Justification of the Study There is a high prevalence of impacted third molars, often accompanied by a range of postoperative complications.
- Trial name
- CESE-3M (NCT07304882)
- Testing
- serratiopeptidase, Escin, Conventional drugs
- Where
- Yemen
- Volunteers
- 24 people
- Sponsor
- University of Science and Technology, Yemen
Pain
Analgesic Effect of Different Combinations of Dexketoprofen Trometamol With Tramadol Hydrochloride in a Model of Moderate to Severe Pain
The purpose of this study is to evaluate the analgesic efficacy of Dexketoprofen Trometamol and Tramadol Hydrochloride given in combinations and the analgesic efficacy of each single component in comparison to placebo on moderate…
- Trial name
- DEX-TRA 02 (NCT01307020)
- Testing
- Dexketoprofen Trometamol, Tramadol Hydrochloride, Ibuprofen
- Where
- 16 sites in Germany, Hungary and 4 more
- Volunteers
- 745 people
- Sponsor
- Menarini Group
Pain, Edema
Leukocyte- and Platelet Rich Fibrin (L-PRF) Application in Impacted Mandibular Third Molar Removal Surgery
The purpose of this study was to evaluate the influence of leukocyte- and platelet-rich fibrin (L-PRF) on impacted mandibular third molar (IMTM) extraction wound healing, patient postoperative discomfort, and incidence of…
- Conditions
- Pain, Edema, Wound Heal
- Trial name
- NCT03357484
- Testing
- Leukocyte- and platelet rich fibrin, Blood clot
- Where
- Lithuania
- Volunteers
- 30 people
- Sponsor
- Lithuanian University of Health Sciences
Impacted Third Molar Tooth, Tooth Extraction Status Nos
Clinical Validation of a Novel Classification for Predicting Surgical Complexity in Mandibular Wisdom Teeth Surgery
The study evaluates and validates a new classification proposed by Juodzbalys and Daugela in 2013 predicting the complexity of impacted mandibular third molars surgical extraction, comparing it with other two, scientifically…
- Trial name
- NCT02519426
- Testing
- Mandibular third molar surgery
- Where
- 2 sites in Italy, Lithuania
- Volunteers
- 110 people
- Sponsor
- Lithuanian University of Health Sciences
Impacted Mandibular Third Molar
The Effect of Topical Application of Hyaluronic Acid and Melatonin Mixture Following Surgical Extraction of Impacted Mandibular Third Molars .
This randomized controlled clinical trial aims to evaluate the clinical and radiographical effects of the application of a mixture of hyaluronic acid and melatonin after surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07735806
- Testing
- Hyaluronic acid and Melatonin mixture, Gel foam
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University
Surgical Flaps, Oral Surgical Procedures
Oral Flap Outline and Local Blood Supply After Surgical Removal of Lower Third Molar Teeth
Wisdom teeth in the lower jaw are frequently buried in bone and must be taken out surgically. To reach the tooth, the surgeon lifts the gum away from the bone as a flap, and the shape of that flap is left to the surgeon's…
- Conditions
- Surgical Flaps, Oral Surgical Procedures, Regional Blood Flow, Tooth, Impacted
- Trial name
- NCT07758192
- Testing
- Sulcular flap elevation for wisdom tooth removal, Three-cornered flap elevation for wisdom tooth removal
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Betül Taş Özyurtseven
Periodontal Pocket, Periodontal Bone Loss
Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets
To evaluate the clinical effect of site preservation after third molars extraction by using tooth extraction of third molars with site preservation using bio-oss and bio-guide in preventing the formation of deep periodontal…
- Conditions
- Periodontal Pocket, Periodontal Bone Loss, Impacted Third Molar Tooth
- Trial name
- NCT06318247
- Testing
- site preservation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Post Operative Pain
Evaluation of the Effect of Systemic Proteolytic Enzyme Therapy on Postoperative Inflammatory Response and QoL After Surgical Extraction of Impacted Mandibular Third Molars
1. To compare the postoperative pain between the patients who receive the systemic enzyme therapy and patients in the control group in the third and seventh day. 2.
- Trial name
- NCT05681312
- Testing
- systemic proteolytic enzyme (Tibrolin), Amoxicillin 500mg+metronidazole 500mg+ doliprane 100mg
- Where
- Iraq
- Volunteers
- 55 people
- Sponsor
- University of Baghdad
Impacted Mandibular Third Molar
The Aim of This Study is to Compare the Effects of Two Different Topical Agents (KLOROBEN® and KLORHEX PLUS®) Used in the Surgical Extraction of Mandibular Bilateral Mesioangular Impacted Third Molars on Postoperative Pain, Edema, and Trismus.
This study aims to compare the effects of two commonly used topical mouth sprays on pain, swelling, and limitation of mouth opening after surgical removal of impacted lower wisdom teeth.
- Trial name
- NCT07416136
- Testing
- Kloroben topical spray, Klorhex Plus topical spray
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Healthy Subjects, Hyperalgesia
Effect of High-dose Naloxone Following Third Molar Extraction
Recent studies have focused on the role of endogenous opioids on central sensitization. Central sensitization is known to be impaired or altered in chronic pain conditions, as fibromyalgia or chronic tension headache.
- Conditions
- Healthy Subjects, Hyperalgesia, Inflammations, Endodontic, Pain, Acute
- Trial name
- TME (NCT02976337)
- Testing
- Naloxone, Normal Saline
- Where
- Denmark
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- mads u werner
Impacted Mandibular Third Molar Extraction
Hyaluronic Acid Gel After Impacted Mandibular Third Molar Surgery
Surgical removal of impacted lower wisdom teeth can cause pain, facial swelling, difficulty opening the mouth, and discomfort during wound healing.
- Trial name
- NCT07890272
- Testing
- 0.2% Hyaluronic Acid Gel
- Where
- Vietnam
- Volunteers
- 25 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Pain
Efficacy and Pharmacokinetic-Pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001
A randomised, double-blind, parallel-group, study comparing the analgesic effect of intranasal CT001 to intranasal sufentanil, intranasal ketamine or placebo for treatment of acute pain in adults undergoing surgical removal of an…
- Trial name
- NCT05508594
- Testing
- CT001, Sufentanil, Ketamine
- Where
- Denmark
- Volunteers
- 220 people
- Sponsor
- Cessatech A/S
Impacted Mandibular Third Molar Extraction
Effect of Kinesio Tape Versus Systemic Dexamethasone on Postsurgical Sequels Following Extraction of Impacted Mandibular Third Molars
The surgical removal of lower wisdom teeth is a common procedure that can cause pain, facial swelling, and difficulty in opening the mouth after surgery.
- Trial name
- NCT07353593
- Testing
- Kinesio Tape application, Intramuscular Injection of Dexamethasone, control
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ashraf elanzy
Bone Loss, Regenerative Inflammation
Osteogenic Action of a Medical Device Based on Beta-tricalcium Phosphate (BTCP)
The general objective of this split-mouth study is to analyze the osteogenic action of BTCP during the bone regeneration process following the extraction of impacted mandibular third molars.
- Conditions
- Bone Loss, Regenerative Inflammation, Third Molars Extraction
- Trial name
- BTCP (NCT06935747)
- Testing
- Medical device: beta-tricalcium phosphate, Bovine Hydroxyapatite
- Where
- 2 sites in Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mario Pérez Sayáns
Impacted Third Molar, Postoperative Pain
Natural Enzyme Mouthwash After Third Molar Surgery
This clinical study investigates whether a natural enzyme-containing mouthwash (ORAL7®) can improve healing, pain and mouth opening after the surgical removal of impacted lower wisdom teeth (mandibular third molars), compared to…
- Conditions
- Impacted Third Molar, Postoperative Pain, Trismus, Wound Healing
- Trial name
- NCT07627945
- Testing
- ORAL7® Mouthwash, 0.2% Chlorhexidine Gluconate Mouthwash
- Where
- Malaysia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- MBD MARKETING SDN. BHD.
Impacted Third Molar Tooth
Local Metformin Gel and Impacted Lower Third Molar
Completed medical and dental history will take for all patients and the position of the impacted teeth will evaluate by panoramic films.
- Trial name
- NCT06975839
- Testing
- Metformin, non metformin gel
- Volunteers
- 36 people
- Sponsor
- Fayoum University
Oral Health
Effect of Hypochlorous Acid-containing Mouthwash on Healing After Impacted Wisdom Tooth Surgery
INTRODUCTION: Local chemotherapeutic agents are used to reduce inflammation after impacted tooth extraction and to minimize possible complications, as well as to increase patient comfort.
- Trial name
- Mouthwash (NCT06920485)
- Testing
- Third molar surgery, Pain Medicine, Wound healing
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi