Clinical trials: Impacted Mandibular Third Molar Extraction, active
Postoperative Pain, Facial Swelling
Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery
This randomized, single-blind, controlled clinical trial aims to evaluate the efficacy and safety of Aescin-based herbal extract (Reparil®) compared with Ibuprofen in managing postoperative sequelae following surgical removal of…
- Conditions
- Postoperative Pain, Facial Swelling, Trismus
- Trial name
- Reparil (NCT07244029)
- Testing
- Escin, Ibuprofen 400 mg
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Oral Health
Effect of Hypochlorous Acid-containing Mouthwash on Healing After Impacted Wisdom Tooth Surgery
INTRODUCTION: Local chemotherapeutic agents are used to reduce inflammation after impacted tooth extraction and to minimize possible complications, as well as to increase patient comfort.
- Trial name
- Mouthwash (NCT06920485)
- Testing
- Third molar surgery, Pain Medicine, Wound healing
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Impacted Third Molar Tooth
Lidocaine Patch and Lower Third Molar
Completed medical and dental history will take for all patients and the position of the impacted teeth will evaluate by panoramic films.
- Trial name
- NCT07330726
- Testing
- Lidocaine patch
- Volunteers
- 21 people
- Sponsor
- Fayoum University
Alveolar Bone Loss
Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation
This study is designed to evaluate and compare clinically and radiographically the effectiveness of Demineralized Dentin Allograft (DDA) versus Demineralized Dentin Autograft (Auto-DD) for preservation of alveolar ridge…
- Trial name
- NCT06457373
- Testing
- Demineralized Dentin Allograft, Demineralized Dentin Autograft
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Horus University
Oral Health Care
The Effect of Supplementary Foods Containing Trypsin, Chymotrypsin and Serratia Peptidase on Healing After Impacted Wisdom Tooth Surgery
Introduction: The aim of this study was to determine the effects of a dietary supplement containing trypsin, chymotrypsin, and serratia peptidase (Tripser Forte N30, Incir Pharma, Turkey) on postoperative healing and to determine…
- Trial name
- Trypsin (NCT07269171)
- Testing
- Pain Assessment, Number of Analgesics Needed, Edema Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Pain (Visceral, Somatic, or Neuropathic)
Postoperative Pain and Swelling After Flap vsFlapless Technique For Mandibular Third Molar Surgery
This randomized controlled trial evaluates postoperative pain and facial swelling following surgical removal of partially impacted mandibular third molars using flap versus flapless techniques.
- Trial name
- NCT07247929
- Testing
- flap technqiue for mandibular third molar extraction Arm A, flapless technquie arm b
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Post Operative Swelling
Assessment of Post Operative Swelling Among Patients Following Extraction of Impacted Third Molars
This randomized controlled trial aims to compare Ward's incision and Comma incision regarding postoperative swelling following extraction of impacted mandibular third molars.
- Trial name
- APOSTM (NCT07655089)
- Testing
- Ward's Incision, Comma Incision
- Volunteers
- 116 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluating The Use of CGF Made Plugs in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) plugs help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07484997)
- Testing
- Concentrated Growth Factor (CGF) Plug
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Impacted Mandibular Third Molar
Comparison of Electrocautery and Scalpel Blade Incisions of Impacted Mandibular Third Molars
This randomized controlled trial aims to compare electrocautery and scalpel blade incisions during surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07723326
- Testing
- scalpel blade incision, electrocautery incision
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Riphah International University
Bone Loss, Regenerative Inflammation
Osteogenic Action of a Medical Device Based on Beta-tricalcium Phosphate (BTCP)
The general objective of this split-mouth study is to analyze the osteogenic action of BTCP during the bone regeneration process following the extraction of impacted mandibular third molars.
- Conditions
- Bone Loss, Regenerative Inflammation, Third Molars Extraction
- Trial name
- BTCP (NCT06935747)
- Testing
- Medical device: beta-tricalcium phosphate, Bovine Hydroxyapatite
- Where
- 2 sites in Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mario Pérez Sayáns
Alveolar Bone Loss, Periodontal Pocket
Regenerative Gel (Emdogain®) for Healing After Wisdom Tooth Extraction
This study investigates whether the intraoperative application of a specialized regenerative gel (Emdogain®) can improve the periodontal health of the mandibular second molar by preventing or reducing the formation of tissue…
- Conditions
- Alveolar Bone Loss, Periodontal Pocket, Impacted Tooth With Abnormal Positioning
- Trial name
- NCT07718932
- Testing
- Enamel Matrix Derivative (Emdogain®)
- Where
- 2 sites in Greece
- Volunteers
- 70 people
- Sponsor
- Aristotle University Of Thessaloniki
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluating The Use of CGF Made Gel in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) Gel help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07520097)
- Testing
- Concentrated Growth Factor (CGF) Gel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Impact Molar
Clinical and Radiographic Evaluation of Local Application of Melatonin on Postoperative Outcomes After Surgical Removal of Impacted Mandibular Third Molar
Clinical and Radiographic Evaluation of Local Application of Melatonin on Postoperative Outcomes after Surgical Removal of Impacted Mandibular Third Molar: A Randomized Controlled Study
- Trial name
- NCT07374536
- Testing
- Control, Melatonin gel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Impacted Mandibular Third Molar Extraction, Dentin Graft
Autologous Dentine Graft Compared to Xenograft in Managing Periodontally Compromised Second Molar After Third Molar Removal
The goal of this study is to evaluate the efficacy of autologous dentin graft (ADG) in treating periodontal defects on the distal aspect of mandibular 2nd molar (M2) after surgical removal of impacted mandibular 3rd molar (M3) by…
- Conditions
- Impacted Mandibular Third Molar Extraction, Dentin Graft, Xenograft, Bone Defects
- Trial name
- NCT07362394
- Testing
- Autologous dentin graft, Xenograft
- Where
- Malaysia
- Volunteers
- 34 people
- Sponsor
- National University of Malaysia
Impacted Third Molar Tooth
Local Metformin Gel and Impacted Lower Third Molar
Completed medical and dental history will take for all patients and the position of the impacted teeth will evaluate by panoramic films.
- Trial name
- NCT06975839
- Testing
- Metformin, non metformin gel
- Volunteers
- 36 people
- Sponsor
- Fayoum University
Facial Swelling, Tooth Position Anomalies
Platelet-Rich Fibrin as an Antibiotic Delivery Vehicle in Mandibular Third Molar Surgery
The present study aims to evaluate the effect of platelet-rich fibrin (PRF) used as a local antibiotic delivery vehicle on postoperative outcomes, including facial swelling, trismus, and pain, following mandibular third molar…
- Conditions
- Facial Swelling, Tooth Position Anomalies, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT07764757
- Testing
- Antibiotic-enriched Platelet-Rich Fibrin (PRF), Platelet-Rich Fibrin (PRF)
- Where
- Italy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice