Clinical trials: Impaired Driving
Impaired Driving, Sleep Driving
Objective Assessment of the Effects of Shift Work on Drowsiness and Driving Impairment in Hospital Staff
The purpose of this protocol is to assess the risk of drowsy driving amongst shift workers using objective measures of drowsiness and driving performance in an instrumented research vehicle.
- Trial name
- NCT01672489
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cannabis Use, Driving Impaired
Neural Correlates of Driving and Cannabis
Driving is a set of complex tasks and requires use of multiple cognitive domains, including attention, planning, and memory. In laboratory studies, the main psychoactive component in cannabis, delta-9-tetrahydrocannabinol (THC)…
- Trial name
- NCT03581058
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Unity Health Toronto
Prevalence of Psychoactive Substances in Road Traffic, Psychoactive Substances in Accident Involved Drivers
Alcohol and Other Psychoactive Substances in Road Traffic - a Case-control Study
The main purpose of the study is to determine the accident risk when driving under the influence of psychoactive substances, including alcohol (DUI).
- Conditions
- Prevalence of Psychoactive Substances in Road Traffic, Psychoactive Substances in Accident Involved Drivers, Relative Risk Estimation of Accident Involvement for Impaired Drivers
- Trial name
- NCT00570518
- Where
- Finland
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Cannabis
Detection of Cannabis Impairment With ISBRG's SpotLight-THC
Subjects will participate in a 2-visit study protocol in which they will be administered cannabis of pre-determined concentrations and asked to complete a simulated drive in a driving simulator.
- Trial name
- NCT05276232
- Testing
- Cannabis(THC) inhaled
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- ISBRG Corp
Choroidal Neovascularization Secondary to Pathologic Myopia
A Study of the Criteria Establishing the Need for Re-treatment With Ranibizumab Upon Relapse in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia.
The primary objective of the study was to investigate current criteria driving re-treatment in patients affected by Choroidal Neovascularization (CNV) secondary to Pathologic Myopia (PM) and experiencing a relapse of the disease…
- Trial name
- OLIMPIC (NCT02034006)
- Testing
- Ranibizumab
- Where
- 31 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Novartis Pharmaceuticals
HIV, Cognition - Other
Speed of Processing Training in Adults With HIV
As people age with HIV, the synergistic effects with normal age-related cognitive declines will accentuate and/or accelerate declines in cognitive functioning which can be detected as early in one's 40s.
- Conditions
- HIV, Cognition - Other, Impaired Driving
- Trial name
- SOP (NCT02758093)
- Testing
- Speed of Processing Training, Internet Navigational
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- University of Alabama at Birmingham
Drunk Driving
Leveraging Transdermal Alcohol Monitoring to Reduce Drinking Among DWI Defendants
The current study will evaluate the efficacy of contingency management (i.e., reinforcement for avoiding heavy drinking) among adults arrested for drunk driving and who are at risk for ongoing heavy drinking.
- Trial name
- NCT03638596
- Testing
- Contingency Management, Control
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Psychomotor Impairment
Combined Alcohol and Cannabis Effects on Skills of Young Drivers
Alcohol and cannabis are the two most widely used substances of abuse in the world and are the psychoactive substances most often found in seriously and fatally injured drivers.
- Trial name
- NCT03106363
- Testing
- alcohol, delta 9 tetrahydrocannabinol
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Shift-Work Sleep Disorder, Insomnia
Fire Fighter Fatigue Management Program: Operation Healthy Sleep
Firefighters work some of the most demanding schedules known under highly stressful and demanding conditions. The need to work frequent extended shifts and long work weeks leads to acute and chronic partial sleep deprivation as…
- Conditions
- Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT01988129
- Testing
- Sleep disorders education and screening
- Where
- United States
- Volunteers
- 1,189 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Excessive Daytime Sleepiness, Obstructive Sleep Apnea (OSA)
Validating a Novel Driving Simulation-based MWT Against the Standard MWT in an OSA-cohort Challenged by CPAP-withdrawal
In brief, the proposed study will evaluate a recently proposed naturalistic, driving simulation test to identify and measure sleepiness behind the wheel, one of the most underestimated causes of road accidents.
- Conditions
- Excessive Daytime Sleepiness, Obstructive Sleep Apnea (OSA), CPAP Treatment, Driving Simulator Performance
- Trial name
- DS-MWT2 (NCT06872593)
- Testing
- CPAP-withdrawal, Test Sequence
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Stefan Lakämper
Parkinson Disease, Driving Impaired
Using Advanced Driver Assistance Systems (ADAS) as an Intervention Strategy for Drivers With Parkinson's Disease
Parkinson's disease (PD) impacts an individual's fitness to drive in a number of ways that increase the crash risk in this population.
- Trial name
- NCT03195608
- Testing
- Lane change assistance system, Active Control
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Western University, Canada
Impaired Driving
MedDrive's Responsiveness to Alcohol
This four-way, dose-response, crossover, double blind, placebo-controlled, randomised validation study investigates the responsiveness of MedDrive, a computed battery of neuropsychological tasks, to different doses of alcohol.
- Trial name
- OH-MedDrive (NCT01781273)
- Testing
- Ethanol, Cranberry juice
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Dementia, Mild Cognitive Impairment
Eye Scanning for Safety Driving
This is an experimental study protocol to investigate the use of vision-based assessments like eye-tracking and visual processing tests to evaluate driving ability in older adults with and without dementia.
- Conditions
- Dementia, Mild Cognitive Impairment, Older Adults
- Trial name
- NCT06396273
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loughborough University
MCI, Subjective Cognitive Decline
Senior Driving Simulation Training for Subjective Cognitive Decline and Mild Cognitive Impairment
This study aims to establish the Senior Driving Simulation Training (SDST) for Subjective Cognitive Decline (SCD) and Mild Cognitive Impairment (MCI), and explore the effectiveness of Senior Driving Simulation Training (SDST) on…
- Conditions
- MCI, Subjective Cognitive Decline, Healthy Aging
- Trial name
- SDST (NCT05380284)
- Testing
- Senior Driving Simulation Training, Waiting list control
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Driving Performance, Cognitive Impairment
The Effects of Cannabidiol on the Driving Ability of Healthy Adults
A randomized, parallel-group, double-blind, exploratory two-arm trial to assess the effects of CBD on driving ability along with changes in psychological status (i.e. mood, drowsiness, sedation) and cognitive function.
- Conditions
- Driving Performance, Cognitive Impairment, Sedation Complication, Mood
- Trial name
- NCT04590495
- Testing
- 300 mg Cannabidiol (CBD) oil
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Cannabis Intoxication
Detection of Cannabis Impairment With an Eye Tracker
Cannabis is one of the widely used psychoactive substances in the world. With increasing legalization, the prevalence of driving under the influence of cannabis will undoubtedly rise.
- Trial name
- ACS (NCT03813602)
- Testing
- Cannabis Sativa
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Underage Drinking, Driving Under the Influence
Project MADD - NIH Underage DUI and Ride
Project MADD was designed to attempt to curb the alarming trends related to drunk driving and to move the field forward by testing a brief parent-intervention's ability to change adolescents' drinking, impaired driving, and…
- Conditions
- Underage Drinking, Driving Under the Influence, Drinking, Teen
- Trial name
- NCT03506880
- Testing
- MADD Materials, Surgeon General Materials
- Where
- United States
- Volunteers
- 2,352 people, healthy volunteers welcome
- Sponsor
- Penn State University
Psychomotor Impairment
Alcohol Effects on Driving-related Skills of Young Drivers
Given the known driving behavior of Driving Under the Influence of Alcohol and some of its parallel to driving under the influence of cannabis, this supplemental study aims to validate the sensitivity of the primary and secondary…
- Trial name
- NCT02710578
- Testing
- Alcohol
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Marijuana Usage, Alcohol Drinking
Neuroscience of Alcohol and Marijuana Impaired Driving
Alcohol is one of the most widely used intoxicants. The effects of driving while intoxicated are well documented, leading to the laws and regulations behind drunk driving.
- Trial name
- NCT03431987
- Testing
- One day with a dose of active THC cannabis paired with alcohol
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Cannabis Smoking, Driving Impaired
Cannabis Consumption and Driving Impairment Assessment on a Closed Course
In a true experiment, roughly 300 volunteer participants will smoke active cannabis, a corresponding placebo, or no substance at all (control).
- Trial name
- NCT06059677
- Testing
- Active smoked cannabis
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bayliss J. Camp, PhD