Clinical trials: Impaired Quality of Life
Stroke, Caregiving Burden
CaknaStrok Education Package for Stroke Caregivers
This study evaluated the feasibility and potential effectiveness of the CaknaStrok Education Package (CEP), a culturally tailored education package developed to support informal caregivers of stroke survivors.
- Conditions
- Stroke, Caregiving Burden, Caregiver, Caregiver Burden for Those Who Care for Adults With Impaired Functional Status
- Trial name
- CaknaStrok (NCT07807332)
- Testing
- CaknaStrok Education Package (CEP)
- Where
- Malaysia
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Clinical Research Centre, Malaysia
Psychological Distress, Quality of Life
Psychological Impairment Due to Covid-19
Hospital staff and emergency personnel are expected to suffer impaired psychological outcomes during a pandemic in terms of Quality of Life, anxiety, depression or other outcomes.
- Trial name
- NCT04368312
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Essen
Mild Cognitive Impairment (MCI), Depression
Brain Aging and Treatment Response in Geriatric Depression
The proposed project will evaluate the role of neuroimaging biomarkers of brain aging (i.e., neurodegenerative and vascular brain changes) and mild cognitive impairment in the patterns of treatment response to memantine combined…
- Trial name
- NCT01902004
- Testing
- Escitalopram, Memantine
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of California, Los Angeles
Breast Cancer
Intellectual Impairment in Women With Breast Cancer
RATIONALE: Breast cancer and its treatment may cause changes in a patient's ability to think, learn, and remember. Gathering information about a woman's genes, brain function, and personal history may help doctors learn more…
- Trial name
- NCT00896324
- Testing
- Cognitive Rehabilitation, Active Neurofeedback Training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
HIV/AIDS, Cognitive Impairment
A Randomized Pilot Trial Evaluating the Impact of a Yoga Intervention on Cognition in Older Adults Infected With HIV
Approximately 50% of people living with HIV (and as many as 80% over the age of 50) have difficulties with cognitive functions such as memory and thinking that can have a profound negative impact on activities of daily living and…
- Conditions
- HIV/AIDS, Cognitive Impairment, Aging, Mobility Limitation
- Trial name
- NCT03071562
- Testing
- Yoga-mindfulness
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Adria Quigley
Stroke, Cognitive Impairment
Multicontextual Treatment Approach in Stroke
BACKGROUND: It is known that cognitive disorders affect the rehabilitation of stroke patients but which cognitive rehabilitation intervention should apply to stroke patients and what their effects are on their life is not clear…
- Conditions
- Stroke, Cognitive Impairment, Quality of Life
- Trial name
- NCT06186661
- Testing
- neurophysiological exercise, cognitive rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ozden erkan
Physical Functional Impairment, Cognitive Impairment
Community Recreation to Enhance Function in Aging
This aim of this study is to examine the therapeutic impacts of a group-based recreational program that delivers guided visual artmaking and dual-task exergaming, to older adults.
- Trial name
- NCT07104435
- Testing
- Artmaking and exergaming
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Obstructive Sleep Apnea, Cognitive Impairment
Cognitive Function and Quality of Life in Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA) is a common condition that disrupts normal breathing during sleep. Beyond causing daytime tiredness, OSA can also impact a person's cognitive functions, such as their attention span, memory, and…
- Conditions
- Obstructive Sleep Apnea, Cognitive Impairment, Quality of Life
- Trial name
- NCT07678918
- Volunteers
- 86 people
- Sponsor
- Assiut University
Cognitive Impairment, Physical Functioning
REducing SEDENTary Behaviour May Slow Cognitive Decline in Older Adults With Mild Cognitive Impairment: A Pilot Study
With the nation's fastest growing demographic being adults over 65, one in every three seniors is estimated to die from Alzheimer's Disease (AD).
- Conditions
- Cognitive Impairment, Physical Functioning, Quality of Life
- Trial name
- RESEDENT (NCT03439059)
- Testing
- Reducing Sedentary Behaviour Group
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Western University, Canada
Periodontal Diseases, Oral Halitosis
The Effect of Regular Home Use of Dual-light Antibacterial Photodynamic Therapy (aPDT) or the Use of a Powered Toothbrush in Older Individuals With Periodontitis and Mild Cognitive Impairment.
Objective: To compare three different oral hygiene regimens regarding plaque index (PI), bleeding on probing (BOP), the number of deepened periodontal pockets ≥4 mm (PPD), oral halitosis, and changes in oral health-related…
- Trial name
- e-DENT II (NCT07166224)
- Testing
- Oral-B Powered toothbrush, Dual-Light aPDT Treatment - Lumoral
- Where
- 2 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Blekinge Institute of Technology
Schizophrenia, Balance; Distorted
Comparison of the Effects of Physical Activity and Virtual Reality Training in Patients With Schizophrenia
The current study aims to compare the effects of physical activity and Virtual Reality training on physical function, cognition and quality of life in patients with Schizophrenia.
- Conditions
- Schizophrenia, Balance; Distorted, Cognitive Impairment
- Trial name
- NCT07173465
- Testing
- Virtual Reality (VR), Physical Activity (PA group), occupational therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Yeditepe University
Stroke
Effects of Mobile Application-Based Cognitive Training Along With Aerobic Training
This randomized controlled trial will determine the effects of combining mobile application-based cognitive training with aerobic exercise on cognitive function and the effects of combining mobile application-based cognitive…
- Trial name
- NCT07148453
- Testing
- Experimental Group, Control Group
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Depression
Effectiveness of Methylphenidate in Improving Cognition and Function in Older Adults With Depression
This study will evaluate the safety and effectiveness of methylphenidate in improving cognition and function in older adults with depression.
- Trial name
- NCT00602290
- Testing
- Citalopram, Methylphenidate (MPH)
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of California, Los Angeles
Cognitive Impairment, Aging
Influence of Overground Walking on Biomarkers, Cognitive Function, and Quality of Life in Elderly With Mild Cognitive Impairment
The purpose of this research is to investigate the impact of overground walking as a part of a rehabilitation program on the increase in Brain-derived neurotrophic factor (BDNF) levels, decrease in IL-6 levels, decrease in hs-CRP…
- Trial name
- NCT06029920
- Testing
- Overground Walking
- Where
- Indonesia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Fibromyalgia, Work Productivity
Evaluation of Work Productivity and Activities of the Fibromyalgia Patients' Relatives
Patients suffering from fibromyalgia (FM) are challenged by symptoms such as chronic pain, fatigue, sleep disturbance and emotional distress.
- Conditions
- Fibromyalgia, Work Productivity, Quality of Life, Pain, Chronic
- Trial name
- NCT06357793
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Macular Degeneration
A Long-Term Monitoring Study of the IMT-002 Patients
This is a 5-year study of patients implanted with the Implantable Miniature Telescope (IMT by Dr. Isaac Lipshitz) under Protocol IMT-002.
- Trial name
- NCT00976235
- Testing
- IMT - Implantable Miniature Telescope
- Where
- 28 sites in United States
- Volunteers
- 129 people
- Sponsor
- VisionCare, Inc.
Cushing Syndrome
Quality of Life, Fatigue and Cognitive, Affective and Emotional Dysfunction in Patients With Cushing's Syndrome
This is a prospective, multi-center, case-control study where neurocognitive function will be evaluated in 36 patients with Cushing syndrome (CS) and 36 controls matched for age, gender and education.
- Trial name
- NCT03211624
- Where
- 3 sites in Netherlands, Spain and 1 more
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Dementia, Neurocognitive Disorders
Effectiveness and Cost-Effectiveness of Robot Therapy With the Paro Robot in People Living With Dementia
The purpose of this study is to evaluate the effectiveness and cost-effectiveness of group robot therapy with the PARO therapy robot in terms of quality of life and neuropsychiatric symptoms in people living with dementia in…
- Conditions
- Dementia, Neurocognitive Disorders, Mild Cognitive Impairment
- Trial name
- NCT05884424
- Testing
- PARO Therapy Robot
- Where
- 15 sites in Spain
- Volunteers
- 123 people
- Sponsor
- Instituto de Mayores y Servicios Sociales (IMSERSO)
Psoriatic Arthritis, Psoriasis
Psoriatic Arthritis Treated With Liraglutide Therapy: a QUality of Life and Efficacy Study
Exploratory, double-blind randomized, placebo-controlled, Phase II study to evaluate the effect(s) of short-term administration of liraglutide, a GLP-1R (glucagon-like peptide-1 receptor) agonist on joint and skin inflammation in…
- Conditions
- Psoriatic Arthritis, Psoriasis, Impaired Glucose Tolerance, Type 2 Diabetes
- Trial name
- PLAQUE (NCT02472717)
- Testing
- liraglutide
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Stroke
Effects of Combined Cognitive Training With Aerobic Exercise in Stroke Patients With MCI
Cognitive impairments have severe impact on functional recovery and quality of life after stroke. Current evidence indicated that combining exercise and cognitive training may provide additional benefits on cognition in stroke.
- Trial name
- NCT04012866
- Testing
- Aerobic exercise training, Computerized cognitive training, Control training
- Where
- 4 sites in Taiwan
- Volunteers
- 75 people
- Sponsor
- Chang Gung Memorial Hospital