Clinical trials: Impaired Synaptic Plasticity
Mild Cognitive Impairment
Memory Training and Neural Plasticity
This study will evaluate the efficacy of working memory training in older adults with amnestic mild cognitive impairment (MCI).
- Trial name
- WMTrain (NCT05380739)
- Testing
- Working Memory Training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Michigan
Schizophrenia
Training-induced Cerebral Reorganization in Schizophrenia
The purpose of this study is to reveal the effects of computer-aided cognitive-auditory training on cerebral reorganization in schizophrenia.
- Trial name
- NCT00695708
- Testing
- Brain Fitness Program, Cogpack
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Mild Cognitive Impairment, Chronic Kidney Diseases
Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity
The purpose of this study is to see if 6 months of home-based walking will improve memory, and brain structure and function, compared to health education in older adults that have chronic kidney disease and mild cognitive…
- Trial name
- EXEC (NCT05655325)
- Testing
- Home-based walking exercise, Attention control
- Where
- 2 sites in United States
- Volunteers
- 144 people
- Sponsor
- Columbia University
Cancer Survivors, Chemotherapy-related Cognitive Impairment
Neuroplasticity-Based Cognitive Remediation for Chemotherapy-Related Cognitive Impairment
The investigators propose to apply neuroplasticity-based computerized cognitive remediation (nCCR) to treat chemotherapy-related cognitive impairment (CRCI).
- Trial name
- NCT04230863
- Testing
- Neuroplasticity-based Computerized Cognitive Remediation
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Vanderbilt University Medical Center
Mild Cognitive Impairment
Improving Neurological Health With Acetylcholine Via Neuroplasticity-based Computerized Exercise in Mild Cognitive Impairment
This study is a validation study to evaluate efficacy of two neuroplasticity-based, computerized cognitive training programs to improve neurological and neuropsychological health in older adults with mild cognitive impairment…
- Trial name
- INHANCE-MCI (NCT07243600)
- Testing
- Computerized speed-based cognitive training, Computerized executive function cognitive training
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Posit Science Corporation
Mild Cognitive Impairment, Memory Impairment
Enhancing Frontal Lobes Plasticity in Mild Cognitive Impairment
More than 5 million people live with Alzheimer's dementia (AD) in North America. No effective treatment exists yet probably because by the time AD has developed it is too late to intervene.
- Trial name
- PAS-MCI (NCT04583215)
- Testing
- Paired Associative Stimulation (PAS)
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health