Clinical trials: Impairment of Attention
Central or Peripheral Visual Impairment
Study of Visual-spatial Attention by Eye Tracking as a Function of Central or Peripheral Visual Impairment
The objective of this pilot work is to determine the role of central and peripheral visions in explicit attention processes (saccade planning) in the case of visual impairment.
- Trial name
- BEHAVE (NCT03505398)
- Testing
- microperimetry, visual acuity, automated visual field
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Nantes University Hospital
Impaired
A Study on Effects of Acupressure Among the Frail Elderly in Residential Care Services for the Elderly
Acupressure has been used for thousands of years in China. Through applying pressure on the specific acupoints based on Traditional Chinese Medicine theory, acupressure could promote relaxation and wellness, balance yin-yang and…
- Trial name
- NCT02491216
- Testing
- Acupressure
- Where
- China
- Volunteers
- 65 people
- Sponsor
- The University of Hong Kong
Mild Cognitive Impairment
The Effect of Transcranial Direct Current Stimulation on Visual Attention in Mild Cognitive Impairment
Progressively causes the breakdown of cognitive functions and impairs quality of life for patients and their caregivers. In addition to memory impairment, visual attention is also compromised, even at the stage of mild cognitive…
- Trial name
- NCT03974087
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- Czechia
- Volunteers
- 35 people
- Sponsor
- Masaryk University
Traumatic Brain Injury, Attention Deficit
Effect of Fixed vs. Tailored Intensity tDCS for Attention Deficit After TBI
Traumatic brain injury (TBI) is an important global health concern. Recently, advances in neurocritical care have led to an increase in the number of recovering TBI patients, and concomittantly in the incidence of complications…
- Conditions
- Traumatic Brain Injury, Attention Deficit, Cognitive Impairment
- Trial name
- NCT05302362
- Testing
- transcranial direct current stimulation
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Seoul National University Hospital
Driving, Intoxication
Validation of Driving Simulator to Blood Alcohol Concentration Standards for Impaired Driving
The proposed study will validate and determine sensitivity of our new driving simulator, created to evaluate driving ability in a related study to show similar driving performance between patients on chronic opioid treatment and…
- Conditions
- Driving, Intoxication, Impairment, Alcohol Impaired Driving
- Trial name
- ALCDrive (NCT00559819)
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Driving Under the Influence
Whole Blood-plasma-oral Fluid Ratios of Psychoactive Drugs and Medicines
The aim of this study is to get new information on the whole blood-plasma-oral fluid ratios of psychoactive drugs which are encountered in traffic.
- Trial name
- NCT00650130
- Where
- Finland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Schizoaffective Disorder, Bipolar Type, Bipolar Disorder
Psychoneuromentalism Disorder: A Medical Condition That Affects People With Psychological Impairments From Health Issues
Psychoneuromentalism Disorder is a disorder arising in the mind; that is related to the mental and emotional state of a person. It is the science of mental life. The body has a natural design to heal itself.
- Conditions
- Schizoaffective Disorder, Bipolar Type, Bipolar Disorder, ADHD - Combined Type, Dissociative Disorder
- Trial name
- PNMD (NCT06235177)
- Testing
- Decompartmentalization Framework, Liquid Herbal TInctures, Mental Imagery
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Essence of Integrative Health and Medicine Practice
Schizophrenia, Schizoaffective Disorder
Guanfacine Adjunctive Treatment to Atypical Antipsychotics for Cognitive Dysfunction in Schizophrenia
Our overall aim is to determine if the administration of guanfacine in combination with aripiprazole, olanzapine, quetiapine, and/or risperidone is significantly more effective than any of those medications alone in treating some…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Cognitive Impairment
- Trial name
- Guanfacine (NCT00469664)
- Testing
- Guanfacine/Tenex
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Cognitive Change, Memory; Disturbance, Mild
The Influence of Food for Special Dietary Use - Spread Enriched With 5-hydroxytryptophan, Theanine and Gamma-aminobutyric Acid on Psychophysiological Functions of Subjects Without Meaningful Organic and Cognitive Pathology
This is a single-centre, single-blind, two-arms, controlled study to assess the efficacy and safety of food for special dietary use enriched with 5-hydroxytryptophan, L-theanine and Gamma-aminobutyric acid in generally healthy…
- Conditions
- Cognitive Change, Memory; Disturbance, Mild, Emotional Regulation, Concentration Ability Impaired
- Trial name
- Spread Bogatyr (NCT05543811)
- Testing
- Food for special dietary use
- Where
- Russia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Scientific Institution
Attention Impaired, Mental Health Issue
Brief Mental Training and Internal Attentional Control
Previous research documented that real-time feedback on attention as well as related forms of mental training (e.g. mindfulness meditation) may be used to train and impact external attentional control.
- Conditions
- Attention Impaired, Mental Health Issue, Rumination
- Trial name
- NCT05353231
- Testing
- Attention Feedback Awareness and Control Training (A-FACT), Mindful Disengagement from Thoughts Training (MDTT)
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Stroke, Hemispatial Neglect
Guanfacine for the Treatment of Spatial Neglect and Impaired Vigilance
To find out if spatial neglect following stroke and brain injury can be reduced using guanfacine, a drug that was shown to improve neglect in two stroke patients in a previous pilot study (Malhotra et al, 2006).
- Trial name
- GASNIV (NCT00955253)
- Testing
- Guanfacine
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- Imperial College London
Renal Impairment
Study to Assess the Plasma Concentration of Tolebrutinib Given as a Tablet to Adult Participants With Renal Impairment Compared to Healthy Participants.
The purpose of this parallel group, Phase 1, open-label, 2-arm study is to assess the effect of severe (Part A) and moderate (Part B, conditional) renal impairment (RI) on pharmacokinetics (PK), safety and tolerability of…
- Trial name
- NCT05282030
- Testing
- tolebrutinib
- Where
- 4 sites in United States, Germany
- Volunteers
- 22 people
- Sponsor
- Sanofi
Attention Impairment
Efficacy and Safety of Donepezil Hydrochloride in Preadolescent and Adolescent Children With Attention Impairment Following Cancer Treatment
The purpose of this study is to evaluate the efficacy, safety and tolerability of donepezil in children with persistent attention impairment that is present at least 12 months after the completion of cancer treatment.
- Trial name
- NCT00688376
- Testing
- Donepezil hydrochloride
- Where
- 31 sites in United States, Argentina and 8 more
- Volunteers
- 72 people
- Sponsor
- Eisai Inc.
Memory Disorder, Retention Disorder, Cognitive
Investigation of Memantine in the Treatment of Memory, Concentration or Attention Problems
In this study, memantine will be tested in a new indication: in the treatment of subjective memory, concentration, or attention problems (subjective cognitive impairment) in the absence of dementia.
- Conditions
- Memory Disorder, Retention Disorder, Cognitive, Subjective Cognitive Impairment, Memory, Concentration or Attention Problems
- Trial name
- NCT01261741
- Testing
- Memantine
- Where
- 14 sites in Germany, United Kingdom
- Volunteers
- 299 people
- Sponsor
- Merz Pharmaceuticals GmbH
Epilepsy Syndrome
Cognitive Impairments in Children With Epilepsy
Since the proportion of language and attentional difficulties in patients with epilepsy is recognized, both in the literature and in the clinical experience of practitioners, it is appropriate to propose a complete…
- Trial name
- NCT05097742
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Bipolar Disorder
Research Study of Bipolar Mood Symptoms and Cognitive Problems
This is a sixteen week, randomized, double-blind add-on study of valacyclovir versus placebo in approximately 60 outpatients meeting diagnostic criteria according to the Diagnostic and Statistical Manual of Mental Disorders (DSM)…
- Trial name
- NCT00428298
- Testing
- Valacyclovir
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Bipolar Disorder, Cognitive Impairment
Quetiapine XR for Cognitive and Functional Disability in Clinically Stable Patients With Bipolar Disorder
Quetiapine has been reported to have beneficial cognitive effects in several randomized controlled trials in schizophrenia. It has not yet been studied in bipolar disorder, but promising results from the use of extended release…
- Trial name
- NCT00746421
- Testing
- Quetiapine XR
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Emory University
Psychosis
Psychosis TMS Study
The main goal of this study is to investigate the neural mechanisms of working memory function in patients with early psychosis using Transcranial Magnetic Stimulation (TMS) in conjunction with functional MRI.
- Trial name
- NCT05857137
- Testing
- Active TMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Movement Disorders (Incl Parkinsonism), Parkinsonian Disorders
Effect of Motor Function, Depression and Sleep Quality on Attention in Parkinson's Disease
Our study was planned to analyze motor function, endurance and sleep attention information in Parkinson's patients with detailed and objective measurements.
- Conditions
- Movement Disorders (Incl Parkinsonism), Parkinsonian Disorders, Attention Impaired, Movement Disorders, Functional
- Trial name
- NCT06283043
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Inonu University
Attention Deficit Hyperactivity Disorder
A Naturalistic Study of Functional Impairment for Individuals With ADHD in the Early Morning and Late Afternoon/Evening Hours
The objective of this study is to assess the burden and impact of ADHD impairment in the early morning and late afternoon/evening hours for adolescents and young adults.
- Trial name
- NCT04473755
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Florida International University