Clinical trials: Implementation, open to volunteers
Chronic Pain, Back Pain
Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back/Neck Pain
The goal of this clinical trial is to learn which treatment works better for veterans with chronic neck or back pain. This study is comparing three treatments: Pain Reprocessing Therapy (PRT), Cognitive Behavioral Therapy (CBT)…
- Conditions
- Chronic Pain, Back Pain, Back Pain Lower Back Chronic, Neck Pain
- Trial name
- POWeR (NCT07137715)
- Testing
- Pain reprocessing therapy (PRT), Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Usual Care
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of Colorado, Denver
Communication Disabilities
Implementation of Communication Disability Collection and Accommodations in Primary Care Settings
This multi-methods-multi-site study aims to adapt and evaluate the effects of an implementation support package of strategies to assist primary care clinics in documenting patients' communication disability (CD) and accommodation…
- Trial name
- DECA (NCT07656584)
- Testing
- Implementation Support Package
- Where
- 5 sites in United States
- Volunteers
- 126,870 people
- Sponsor
- NYU Langone Health
Oral Health Behavior Change, Oral Hygiene, Oral Health
A Just-in-Time Digital Learning Platform for Teacher Oral Health Training
This randomized controlled trial aims to evaluate the effectiveness and implementation of a Just-in-Time Digital Learning Platform designed to improve teachers' oral health literacy and support the delivery of oral health…
- Conditions
- Oral Health Behavior Change, Oral Hygiene, Oral Health, Digital Literacy
- Trial name
- NCT07645612
- Testing
- Just-in-Time Digital Learning Platform for Teacher Oral Health Training
- Where
- Pakistan
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Lung Cancer Screening
Kentucky - Quality Improvement Implementation Lung Cancer Screening (QUILS™) Implementation
This is an optimization pathway for lung cancer screening programs. Enrolled programs will undergo an audit for elements associated with improved quality and retention of patients in the screening process.
- Trial name
- NCT07639255
- Testing
- QUILS System
- Where
- 17 sites in United States
- Volunteers
- 330 people
- Sponsor
- Timothy Mullett
Implementation Research, Artificial Intelligence (AI)
Barriers and Facilitators to Nursing Record With AI Technology Application
The goal of this study is to examine the facilitators and barriers to the comprehensive implementation of AI technology in nursing documentation.
- Conditions
- Implementation Research, Artificial Intelligence (AI), Nursing Documentation Burden
- Trial name
- NCT07532343
- Testing
- AI-based technologies systems to assist with nursing record
- Where
- Taiwan
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Head and Neck Cancer
PromotinG Lung Cancer screenIng Awareness and Implementation in Hispanics/Latinx Head and Neck canceR Survivors
The purpose of this study is to assess the awareness of eligibility of lung cancer screening in Hispanic/LatinX Head and Neck Cancer (HNC) survivors using a survey questionnaire; and to understand the barriers to screening using…
- Trial name
- GUIAR (NCT06124508)
- Testing
- Lung Cancer Screening Education, Semi-Structured Interview, Standard of Care Lung Cancer Screening Program
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Miami
Metabolic Syndrome (MetS), Metabolic Syndrome
Effectiveness and Implementation of a Community-based Health Coach-led Artificial Intelligence (AI)-Powered Digital Self-Regulation Program for Individuals With Metabolic Syndrome (MetS)
This study aims to evaluate the effectiveness of the Lifestyle Intervention for Gentle, Healthy Transformation and Enhanced Weight Reduction-metabolic syndrome (LIGHTER-MetS) program on dietary self-regulation and cardiovascular…
- Trial name
- LIGHTER-MetS (NCT07410325)
- Testing
- LIGHTER-MetS
- Where
- Singapore
- Volunteers
- 316 people
- Sponsor
- National University Health System, Singapore
Heart Failure
Registry BAsed Optimization Of Therapy in Heart Failure
Rationale. Although several pharmacological treatments, namely renin-angiotensin-system inhibitors, sacubitril/valsartan, beta-blockers, mineralocorticoid receptor antagonists and sodium-glucose cotransporter-2 inhibitors…
- Trial name
- REBOOT-HFrEF (NCT07154758)
- Testing
- Screening for need of HFrEF GDMT implementation through SwedeHF
- Where
- 6 sites in Sweden
- Volunteers
- 1,000 people
- Sponsor
- Region Stockholm
Tobacco Use Disorder/Cigarette Smoking, HIV
Smoking Cessation Medication And Rewards Using a Teamlet to Treat Tobacco Use Disorder (SMARTTT 2.0) Among Persons With HIV: A Multi-site Hybrid Type 2 Effectiveness-implementation Trial
Cigarette smoking is an important cause of illness and death among persons with HIV (PWH). This project will study the impact of adding contingency management (use of financial rewards) to receiving medications and counseling on…
- Trial name
- NCT07835555
- Testing
- nicotine patch, nicotine gum, nicotine lozenge, varenicline, bupropion, Multi-target Contingency Management, Teamlet booster
- Where
- 5 sites in United States
- Volunteers
- 794 people
- Sponsor
- Yale University
Total Hip Arthroplasty (THA), Antibiotic Prophylaxis
Infection-related Revision Rates After Single-dose Versus Multiple-dose Antibiotic Prophylaxis in Primary Hip and Knee Arthroplasty: a Comparative Implementation Study.
Prosthetic Joint Infection (PJI) is a significant issue in joint replacement surgeries, causing additional surgeries and substantial healthcare costs.
- Conditions
- Total Hip Arthroplasty (THA), Antibiotic Prophylaxis, Revision Arthroplasty, Total Knee Arthroplasty
- Trial name
- REVISE (NCT07053943)
- Where
- Netherlands
- Volunteers
- 70,000 people
- Sponsor
- JointResearch
Acute Respiratory Distress Syndrome, Post Intensive Care Syndrome
The ICU LIBERATION Study
Acute respiratory distress syndrome (ARDS) is a condition associated with hypoxemia due to noncardiogenic causes and results in high mortality.
- Conditions
- Acute Respiratory Distress Syndrome, Post Intensive Care Syndrome, Treatment Compliance, Quality of Life
- Trial name
- LIBERATION (NCT05844579)
- Where
- Japan
- Volunteers
- 1,000 people
- Sponsor
- Japanese Society for Early Mobilization
Depression, Elder Abuse
Tele-PROTECT Therapy: Effectiveness, Empowerment, and Implementation
The purpose of this randomized trial is to conduct a fully powered effectiveness trial of video-delivered PROTECT (Tele-PROTECT) compared to a video-delivered depression education (DepEd) control condition to be delivered to 140…
- Trial name
- NCT06039930
- Testing
- Tele PROTECT, Depression Education
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Weill Medical College of Cornell University
Stage III Colorectal Cancer
Genetic and Epigenetic Determinants of Response to Fluorouracil-based Adjuvant Chemotherapy in Patients With Stage III Colorectal Cancer
The goal of this laboratory research is to look for genetic and epigenetic markers that can predict which patients with stage III colorectal cancer will benefit from fluorouracil-based adjuvant chemotherapy.
- Trial name
- NCT03127111
- Testing
- Gene mutations analysis, Gene methylation analysis, Gene expression analysis
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Neurodevelpmental Delays, Neurodevelopment
Implementation Outcomes and Cost-effectiveness of Developmental Monitoring for Children Exposed to HIV
The goal of this study is to learn about how to best carry out neurodevelopmental screening methods (tests to see if a young child can use support with brain development) in routine clinic visits in Botswana and Kenya among…
- Conditions
- Neurodevelpmental Delays, Neurodevelopment, Neurodevelopment Outcome
- Trial name
- IMPLEMENT (NCT07457411)
- Testing
- Neurodevelopmental screening
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alzheimer Blood Biomarkers, Alzheimer's Disease (AD)
The BRidge Towards Implementation of Blood-based Biomarkers to Enable Early and Accurate Diagnosis of Alzheimer's Disease
Cognitive disorders have a broad differential diagnosis, and a precise, timely diagnosis is essential for personalized treatment and care.
- Trial name
- BRIDGE-AD2 (NCT07680335)
- Testing
- Plasma p-tau217 and neurofilament light chain results
- Where
- 8 sites in Netherlands
- Volunteers
- 550 people
- Sponsor
- Alzheimercentrum Amsterdam
Anxiety, Depression
Implementation of WHO's Doing What Matters in Times of Stress in Dutch Small and Medium-sized Enterprises (SMEs)
The goal of this cluster randomized controlled trial is to explore if mental health in Dutch small and medium-sized enterprises (SMEs) can be improved by the World Health Organization's online program Doing What Matters in Times…
- Conditions
- Anxiety, Depression, Psychological Distress
- Trial name
- NCT06979089
- Testing
- Doing What Matters in Times of Stress
- Where
- Netherlands
- Volunteers
- 518 people
- Sponsor
- VU University of Amsterdam
Parenting Intervention, Maltreatment
Early Test of an Innovative Child Maltreatment (CM) Prevention Strategy
Millions of children are victims of maltreatment each year in the United States. Research on home visiting programs show that child maltreatment can be prevented; however, these programs struggle to reach families in need and…
- Conditions
- Parenting Intervention, Maltreatment, Prevention
- Trial name
- (CM) (NCT06912685)
- Testing
- Technology Enhanced Implementation Package, SafeCare
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Osteoarthritis of the Hip or Knee
Implementing a Guideline-based Model of Care for Hip and Knee Osteoarthritis in Finland. A Benchmarking-controlled Trial (FIN-OA)
This project aims to bridge the gap between guideline recommendations and clinical practice in osteoarthritis (OA) management. By implementing a systematic, evidence-based model of care, the project seeks to improve patient…
- Trial name
- FIN-OA (NCT06904885)
- Testing
- Implementation of a guideline-based model of care for hip and knee osteoarthritis
- Volunteers
- 10,000 people
- Sponsor
- University of Jyvaskyla
Post Traumatic Stress Disorder
A Hybrid 1 Effectiveness-Implementation Trial of Partner-Assisted Prolonged Exposure for PTSD
PTSD occurs in up to 17% of post-9/11 US Service Members and is associated with long-term functional impairment, family problems, unemployment, and suicidality.
- Trial name
- COOPERATE (NCT06990191)
- Testing
- Partnered Prolonged Exposure (PPE), Prolonged Exposure (PE)
- Where
- 4 sites in United States
- Volunteers
- 420 people
- Sponsor
- United States Department of Defense
Children with Medical Complexity, Child, Only
Emergency Care Action Plans for Infants with Medical Complexity
An Emergency Care Action Plan (ECAP) is a tool intended to be helpful to providers when treating a child with complex medical needs during an emergency.
- Conditions
- Children with Medical Complexity, Child, Only, Infant Morbidity, Infant Conditions
- Trial name
- ECAP (NCT06444282)
- Testing
- Emergency Care Action Plan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Vermont
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.