Clinical trials: Implementation, open to volunteers
Parent-Child Relations
Promoting Socioemotional Development in Early Childhood: Implementation and Evaluation of the VIPP-SD Parenting Intervention in Portugal
The Video-feedback Intervention to Promote Positive Parenting and Sensitive Discipline (VIPP-SD) is an attachment-based intervention aimed at promoting parental sensitivity and the use of developmentally appropriate, non-coercive…
- Trial name
- SAF-Parents (NCT07153198)
- Testing
- VIPP-SD
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Cardiovascular Health Status, Smoking Status
Effectiveness and Implementation Evaluation of NeoMayor for Improving Cardiovascular Health in Chilean Older Adults
This study aims to evaluate the effectiveness and implementation of NeoMayor, a mobile health (mHealth) intervention designed to improve cardiovascular health among older adults at elevated cardiovascular risk in Chile.
- Conditions
- Cardiovascular Health Status, Smoking Status, Physical Activity, Diet Quality
- Trial name
- NEOMAYOR (NCT07633392)
- Testing
- NeoMayor App, Wearable Device Support, Human Health Coach Support
- Where
- 2 sites in Chile
- Volunteers
- 240 people
- Sponsor
- University of Chile
Depression, Insomnia
Implementation of Internet-based Psychotherapy for Symptoms of Depression, Insomnia and Anxiety in Primary Care in the Cities of Indaiatuba and Jaguariuna
The main objective of this study is to evaluate the effectiveness and success of implementing internet-based cognitive behavioral psychotherapy (iCBT) guided by a therapist for symptoms of depression, insomnia and anxiety in…
- Conditions
- Depression, Insomnia, Anxiety
- Trial name
- NCT06817109
- Testing
- interactive technological intervention for improvement of mental health symptoms in Primary Care users Health
- Where
- 2 sites in Brazil
- Volunteers
- 268 people
- Sponsor
- University of Sao Paulo General Hospital
Food Choice, Implementation Science
Healthy Options At Pantries (HOAP) Study
This study will evaluate a digital nudge intervention, Healthy Options At Pantries (HOAP), in the online food pantries of three large charitable food organizations.
- Conditions
- Food Choice, Implementation Science, Food Insecurity, Diet, Healthy
- Trial name
- HOAP (NCT07729436)
- Testing
- Behavioral economics-based Healthy Options At Pantries (HOAP) digital nudge intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Chronic Pain, Musculoskeletal Pain
Improving Health for Older Adults With Pain Through Engagement
The goal of this project is to conduct a randomized, hybrid type 1 effectiveness-implementation trial (N=200) to evaluate the effectiveness and implementation of a 10-week mind-body and walking program (GetActive+) vs treatment…
- Trial name
- iHOPE (NCT06119698)
- Testing
- GetActive+
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Chronic Disease Prevention
Engaging Partners in Caring Communities
The goal of the EPICC observational study is to learn about capacity to implement evidence-based health promotion programs (EBPs) in congregations that are offered semi-structured technical assistance (TA).
- Trial name
- EPICC (NCT06932549)
- Testing
- Technical assistance is designed to integrate Expert Recommendations for Implementing Change (ERIC) strategies, and Getting To Outcomes-TA.
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tennessee State University
Chronic Pain
Effectiveness and Implementation of a Digital Intervention for Pediatric Chronic Pain Co-designed With Patients
Children and adolescents with chronic pain often lack a proper diagnosis and treatment. Research has shown that, if left untreated, it usually doesn't resolve and continues through adulthood.
- Trial name
- Digital SPA (NCT05917626)
- Testing
- Digital SPA
- Where
- 6 sites in Spain
- Volunteers
- 195 people
- Sponsor
- University of Malaga
PrEP Adherence Monitoring
A Hybrid Effectiveness-Implementation Trial of Urine Point-of-Care Assay to Increase PrEP Adherence Among Women in Kenya
The goal of this randomized trial study is to learn if drug-level feedback counseling works to improve oral PrEP adherence in adolescent girls and young women. Researchers will compare urine TFV assay positivity between arms.
- Trial name
- NCT07725679
- Testing
- POC urine TFV test with DLFB
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Washington
Lethal Means Safety, Brief Intervention
Testing Family Firearm Secure Storage Training (FFAST) to Prevent Suicide
Firearms are the lethal means used in over 70% of Veteran suicides with rates of Veteran deaths via self-induced firearm injury rising dramatically (by 64.8%) from 2001 to 2022.
- Conditions
- Lethal Means Safety, Brief Intervention, Concern Significant Others
- Trial name
- FFAST RCT (NCT07692854)
- Testing
- The Family Firearms Secure storage Training (FFAST) Intervention, Health and Stress Counseling
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Asthma, Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Implementation of a Joint Pulmonologist and ENT Consultation in the Care Pathway of Patients Suffering From Asthma and Chronic Rhinosinusitis With Nasal Polyposis: Effectiveness Compared With Consultations by Specialty (CON-PO Study).
Asthma affects the lower respiratory tract (bronchi), whereas chronic rhinosinusitis with nasal polyposis (CRSwNP) involves the upper airways.
- Trial name
- CON-PO (NCT07134686)
- Testing
- Joint consultation, Mucus sampling, Nasal brushing
- Where
- France
- Volunteers
- 195 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Homelessness, Substance Use Disorder (SUD)
Coordinated Access for Addiction Recovery and Equity in VA Supportive Housing
The Department of Housing and Urban Development-VA Supportive Housing (HUD-VASH) Program provides subsidized permanent housing with case management to homeless-experienced Veterans (HEVs).
- Trial name
- CARE-VASH (NCT07141394)
- Testing
- Medication for Addiction Treatment (MAT), Cognitive Behavioral Therapy for Substance Use Disorders (CBT-SUD)
- Where
- United States
- Volunteers
- 7,908 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Suicide Prevention, Suicide Safety Planning
Suicide Safety Planning
The goal of this clinical trial is to learn the best way to provide suicide prevention care to adults receiving outpatient mental health care.
- Conditions
- Suicide Prevention, Suicide Safety Planning, Suicidal Ideation, Suicide Attempt
- Trial name
- STAY (NCT07783490)
- Testing
- Local Care Continuity, Centralized Care Navigation
- Where
- United States
- Volunteers
- 176,000 people
- Sponsor
- Kaiser Permanente
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Implementation Development for Distress Screening in Pediatric Oncology (ID-DISTRESSS)
This study is being done to understand how digital strategies (e.g., electronic health record [EHR]-technology, third-party platforms, and institution-developed solutions) can be used to deliver and respond to evidence-based…
- Trial name
- NCT07908485
- Testing
- Non-Interventional Study
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Oncology Group
Implicit Bias
Virtual Implicit Bias Reduction and Neutralization Training (VIBRANT)
Healthcare providers' implicit bias has been identified as a contributor to longstanding health inequities via negative impacts on the patient-clinician relationship and biased delivery of high-quality evidence-based practices…
- Trial name
- VIBRANT (NCT05970991)
- Testing
- Brief Online Training (BOLT) for measurement-based care (MBC), Virtual Implicit Bias Reduction and Neutralization Training (VIBRANT), Live Post-Training Consultation
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Washington
Parkinson Disease
Adaptive DBS to Offset STN Dysregulation During Exercise in PD
The investigators conduct a prospective study to evaluate the effects of exercise on Parkinson's Disease brain biomarkers detected with the PerceptTM PC neurostimulator.
- Trial name
- NCT06296810
- Testing
- aDBS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
Cancer Survivorship
Evaluating the Implementation of a Need-Based Cancer Survivorship Program
The project aims to conduct an implementation evaluation of the need-based cancer survivorship program using the RE-AIM framework.
- Trial name
- NCT07830368
- Testing
- Moderate needs intervention, High needs
- Where
- 5 sites in Hong Kong
- Volunteers
- 12,500 people
- Sponsor
- The University of Hong Kong
Primary Care
Arrival Time Implementation
This is a prospective clinical trial evaluating how behaviorally informed message framing can improve patient on-time arrival for outpatient visits.
- Trial name
- NCT07314697
- Testing
- Behaviorally informed appointment communications, Control appointment communications
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- University of California, Los Angeles
Pharmacogenomic Drug Interaction, Side Effect of Drug
Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice:
The purpose of this study is to determine whether the implementation of pre-emptive pharmacogenomic (PGx) testing of a panel of clinically relevant PGx markers, to guide the dose and drug selection for 39 commonly prescribed…
- Conditions
- Pharmacogenomic Drug Interaction, Side Effect of Drug, Ineffective Drug Action, Drug Metabolism, Poor, CYP2D6-Related
- Trial name
- PREPARE-Mayo (NCT06322238)
- Testing
- PGx panel test
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Children, Family Engagement
Effective Implementation Control Trial
This study will evaluate the effectiveness and implementation of a theory-driven, WhatsApp-based family engagement intervention designed to improve oral health among primary school children.
- Conditions
- Children, Family Engagement, Oral Health Behavior Change
- Trial name
- NCT07736443
- Testing
- SmileConnect
- Where
- Pakistan
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Suicide
THRIVE: A Recovery-Focused Suicide Prevention Intervention in Crisis Stabilization Centers
Suicide is a major public health concern in the United States, with more than 1.4 million adults attempting suicide and nearly 50,000 adults dying by suicide each year.
- Trial name
- THRIVE (NCT07784634)
- Testing
- Toward Hope, Recovery, Interpersonal Growth, Values, and Engagement (THRIVE), Center Care as Usual
- Where
- 3 sites in United States
- Volunteers
- 552 people
- Sponsor
- University of Alabama at Birmingham
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