Clinical trials: Implementation, open to volunteers
MASH, MASLD
Global Research Initiative for Patients Screening on MASH
GRIPonMASH will assist (primary) health care providers clinicians to implement the latest patient care pathway, as described by the European Association for the Study of the Liver (EASL), to identify patients at risk of severe…
- Conditions
- MASH, MASLD, MASH With Fibrosis, Fibrosis, Liver
- Trial name
- GRIPonMASH (NCT05651724)
- Where
- 13 sites in Belgium, Czechia and 8 more
- Volunteers
- 10,000 people
- Sponsor
- Julius Clinical
CARES, Standard of Care
Hybrid Type I Effectiveness-implementation Cluster Randomized Controlled Trial of CARES
The trial will examine the effectiveness and facilitators and barriers of implementation of CARES, an integrated screening and stepped collaborative care intervention
- Trial name
- CARES (NCT07183527)
- Testing
- CARES, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 1,750 people
- Sponsor
- University of Pittsburgh
Cancer, Exercise
From Exercise Oncology Research to Clinical Practice
Building on previous research that shows the benefits of exercise, this study aims to find out how best to implement exercise in real-world settings.
- Conditions
- Cancer, Exercise, Implementation of Evidence Based Programs, Cost Effectiveness
- Trial name
- PAC ICare (NCT07635589)
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Melanie Keats
Type 2 Diabetes
Development and Pilot Implementation of a Shared Decision-Making Intervention for Type 2 Diabetes Using the Ottawa Framework
The goal of this clinical trial is to evaluate the effectiveness of a shared decision-making (SDM) intervention program based on the Ottawa Decision Support Framework in adult patients with type 2 diabetes (aged ≥18 years…
- Trial name
- NCT07785440
- Testing
- Intervention Group
- Volunteers
- 70 people
- Sponsor
- Anhui Medical University
Stress Disorders, Post-Traumatic
Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure
The goal of this clinical trial is to learn if receiving Trauma-Informed Guilt Reduction (TrIGR) Therapy is as effective as receiving Prolonged Exposure Therapy among veterans with PTSD and trauma related guilt.
- Trial name
- PORT (NCT06296589)
- Testing
- Trauma Informed Guilt Reduction Therapy, Prolonged Exposure Therapy
- Where
- 4 sites in United States
- Volunteers
- 158 people
- Sponsor
- Veterans Medical Research Foundation
Behavioral Intervention, Viral Suppression of HIV Infection
Reactive Driven Support for Treatment, Adherence, Resilience, and Thriving (reSTART) Clinical Trial
Men who are living with HIV and use stimulants face many challenges and barriers that may interfere with remembering to take their HIV medication.
- Conditions
- Behavioral Intervention, Viral Suppression of HIV Infection, ART Adherence
- Trial name
- reSTART (NCT07125235)
- Testing
- reSTART Objective Adherence Self-Monitoring and Postive Affect mHealth Intervention, urine tenofovir point-of-care self-test
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of California, San Francisco
Cancer, Fatigue
Active Living After Cancer: Implementation Within Be Well Acres Homes
The goal of this research study is to learn more about a physical activity program adapted for cancer survivors.
- Trial name
- NCT06907706
- Testing
- Physical Activity/Physical Functioning, Quality of Life
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- M.D. Anderson Cancer Center
Dementia, Cognitive Dysfunction
Preventing Loss of Independence Through Exercise in Community Living Centers
Approximately 40,000 older Veterans with complex care needs receive long-term care in VA Community Living Centers (CLCs). Many CLC staff have limited specialized training to engage Veterans with dementia.
- Trial name
- PLIE-CLC (NCT06972004)
- Testing
- Preventing Loss of Independence through Exercise (PLIE)
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Atherosclerotic Cardiovascular Disease
Study to Evaluate the Impact of a Targeted Lipid Optimization Program on LDL-C Control in At-risk Adult Patients With Dyslipidemia
This study is an open label, randomized, prospective, type I hybrid effectiveness- implementation, pragmatic clinical trial to evaluate the impact of a targeted lipid optimization program on LDL-C control in participants with…
- Trial name
- OPTIMA (NCT07034690)
- Testing
- Educational Material, Standard of care
- Where
- United Arab Emirates
- Volunteers
- 326 people
- Sponsor
- Novartis Pharmaceuticals
Healthy
Health4Life a Digital Intervention to Promote Healthy Lifestyle Behaviours From the Start of Life
The overall aim of this project is to evaluate the effectiveness and implementation of a digital intervention to support parents to create healthy lifestyle behaviours from the start of their infant's life, in order to prevent…
- Trial name
- Health4Life (NCT06798597)
- Testing
- Health4Life app
- Where
- Sweden
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Primary Care Patients, Primary Care Center
Testing the Impact of the MOHR Follow-up Support
This study will evaluate the impact of 3 different strategies to increase engagement of participants in My Own Health Report (MOHR) and health behavior change activities over time.
- Trial name
- NCT07569224
- Testing
- Providing reminder and resources via messages, Reminder and resources sent via navigation, Regular care
- Where
- 6 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Spinal Cord Injuries (Complete and Incomplete), Spinal Cord Injuries (SCI)
Feasibility of Transcutaneous Spinal Stimulation in Rehabilitation
Transcutaneous spinal stimulation (TSS) is a non-invasive neuromodulation approach that delivers electrical stimulation to spinal nerve roots through electrodes placed over the spinal cord.
- Conditions
- Spinal Cord Injuries (Complete and Incomplete), Spinal Cord Injuries (SCI), Spinal Cord Injuries and Disorders (SCI/D)
- Trial name
- NCT07898150
- Testing
- Transcutaneous Spinal Stimulation, Inpatient SCI Physiotherapy, Inpatient SCI Occupational Therapy
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Janelle Unger
Depression, Anxiety
Behavioral Telehealth in Low-resource Primary Care Settings for Anxiety and Depression in Youth
The goal of this clinical trial is to test a brief, behavioral telehealth treatment program (STEP-UP) for depression and anxiety in youths (age 8-16 years old).
- Trial name
- STEP-UP (NCT06273982)
- Testing
- STEP-UP (transdiagnostic behavioral therapy for pediatric anxiety and depression), ARC (assisted referral to community care)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- San Diego State University
Type 2 Diabetes
Implementation of Team Clinic for Type 2 Diabetes (TCT2)
The goal of this clinical trial is to learn if shared medical appointment is an acceptable way to deliver care to youth with type 2 diabetes.
- Trial name
- NCT06923046
- Testing
- Standard of Care, Shared Medical Appointments
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Children's Hospital Los Angeles
Infection, Bacterial, Infection Prevention
Optimising Kangaroo Care to Reduce Neonatal Severe Infection/Sepsis and Resistant Bacterial Colonisation Among High-risk Infants in NICU.
NeoDeco is a pragmatic, multicenter, parallel-group, cluster-randomised hybrid effectiveness-implementation trial designed to evaluate the impact of implementing optimised Kangaroo Care (KC) at the unit level compared to standard…
- Trial name
- NeoDeco (NCT05993442)
- Testing
- Optimised kangaroo care
- Where
- 24 sites in Greece, Italy and 3 more
- Volunteers
- 3,080 people
- Sponsor
- PENTA Foundation
Postoperative Ileus, Colorectal Cancer Control and Prevention
Implementation of an Efferent Loop Stimulation Protocol Prior to Ileostomy Closure at La Paz University Hospital
Stoma creation is a common surgical procedure, employed in certain contexts within general surgery, particularly in colorectal and emergency surgery.
- Conditions
- Postoperative Ileus, Colorectal Cancer Control and Prevention, Stoma - Ileostomy
- Trial name
- NCT06974500
- Testing
- Daily efferent limb stimulation for at least two weeks prior to surgery using saline solution and a thickering agent
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Hospital Universitario La Paz
Type 1 Diabetes, Asthma
EmoTIChealth: Promoting Adolescent Health Through a Serious Game.
The intervention program targets adolescents between 12 and 16 years of age. The intervention program is designed for adolescents during a critical developmental stage marked by significant life transitions, where building strong…
- Conditions
- Type 1 Diabetes, Asthma, Allergic Rhinitis, Food Allergy
- Trial name
- NCT07212530
- Testing
- EmoTIChealth
- Where
- Spain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Urinary Incontinence
Implementing a Mobile Health Application for Women Veterans With Urinary Incontinence (MyHealtheBladder): Function QUERI 3.0
Implementing a Mobile Health Application for Women Veterans with Urinary Incontinence (MyHealtheBladder): Function QUERI 3.0 aims to compare implementation approaches while also gathering information on clinical effects of the…
- Trial name
- MHB (NCT07219433)
- Testing
- Implementation Strategy: Foundational Arm, Implementation Strategy: REACH Arm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Stress, Anxiety
Implementation of a Short Mindfulness-based Program for Young Women in Puerto Rico
The goal of this study is to evaluate the feasibility and acceptability of a revised 4-week mindfulness program among young women with elevated stress and anxiety in Puerto Rico
- Trial name
- NCT06909526
- Testing
- Mindfulness-based stress reduction :MBSR, Usual care
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Emory University
Sleep, Postpartum Depression
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers
Insufficient and disrupted sleep are rarely addressed in expectant and new mothers, despite evidence that disturbed sleep is a modifiable risk factor for negative health outcomes for mothers and their children.
- Conditions
- Sleep, Postpartum Depression, Pregnancy Related, Insomnia
- Trial name
- NCT06737055
- Testing
- Education about behavioral strategies to improve sleep
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
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