Clinical trials: Implementation, open to volunteers
Cancer-related Cognitive Impairment
Electroacupuncture for Cognitive Toxicity in Cancer Survivors: Assessing Implementation, Cost, and Effectiveness for Integration
The goal of this clinical trial is to evaluate the clinical effectiveness and understand the biological mechanisms of electroacupuncture (EA) in reducing cognitive toxicity among cancer survivors.
- Trial name
- EAST-ALIGN (NCT07583979)
- Testing
- True electroacupuncture
- Where
- Singapore
- Volunteers
- 168 people
- Sponsor
- National Cancer Centre, Singapore
Anesthesia, Surgery
Veterans Enhanced Recovery Using Integrative Treatments Around Surgery
The study aims to assess the implementation and effectiveness of Integrative Treatments - Music Medicine, Aromatherapy, and Battlefield Acupuncture - in the management of perioperative pain and anxiety, and in the reduction of…
- Conditions
- Anesthesia, Surgery, Knee Arthropathy
- Trial name
- VERITAS (NCT06333938)
- Testing
- Nonpharmacologic Treatment, Standard Care
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Durham VA Medical Center
Chronic Atrophic Gastritis, Depressive Symptoms
Objective Vascular Biomarkers as Triage for Depression in Chronic Atrophic Gastritis
Depressive symptoms are highly prevalent in patients with chronic atrophic gastritis (CAG) but are frequently under-detected due to stigma and reliance on subjective questionnaires.
- Conditions
- Chronic Atrophic Gastritis, Depressive Symptoms, Depression, Gastrointestinal Diseases
- Trial name
- NCT07319338
- Testing
- Vascular-Psychological Triage Workflow
- Where
- 4 sites in China
- Volunteers
- 520 people
- Sponsor
- China Academy of Chinese Medical Sciences
Non Small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC)
Liquid BiOpsy, Lung and Colon Cancer in AndaluciA
The objective of the LOLA Project is to analyse the impact of adopting xF liquid biopsy panel, in the real world of the Andalusian Health Public System in terms of impact on clinical practice and cost through the assessment of…
- Trial name
- LOLA-PROJECT (NCT06997458)
- Testing
- xF Tempus assay
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
Suicide Ideation, Suicide Attempt
Plan and Protect: Safety Planning for Teens in Rural Emergency Departments
The goal of this observational study is to determine whether implementing a culturally sensitive, tablet-based safety planning program called Plan \& Protect (P\&P) within rural emergency departments can improve home safety and…
- Trial name
- NCT07325474
- Testing
- Plan & Protect safety planning intervention, Care as usual
- Where
- 6 sites in United States
- Volunteers
- 550 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Radiotherapy
Comparison Between Virtual vs in Person on Treatment Follow-up Visits of Radiotherapy
This study aims to evaluate the logistical feasibility and implementation of virtual versus in-person on-treatment follow up visits in a high-volume radiation oncology setting.
- Trial name
- NCT07724548
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Liver Diseases, Liver Transplant; Complications
Design and Implementation of the Pediatric Liver Transplantation Biobank
The purpose of the pediatric liver transplant biobank is to systematically collect clinical specimens from pediatric end-stage liver disease.
- Conditions
- Liver Diseases, Liver Transplant; Complications, Pediatric ALL
- Trial name
- NCT04477967
- Testing
- No intervention
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Chongqing Medical University
Systemic Lupus Erythematosus
Development of a Dietary Intervention Model Based on Genetic Data as an Implementation of a Healthy Lifestyle in the Management of Systemic Lupus Erythematosus Patients
The goal of this clinical trial is to learn if dietary intervention based on genetic data benefits in the management of systemic lupus erythematosus patients. It will also learn about the safety of this intervention.
- Trial name
- NCT07183007
- Testing
- Low gluten diet
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Indonesia
Pseudoxanthoma Elasticum
Impact of Optimized Recruitment and Follow-up of Patients With Pseudoxanthoma Elasticum (PXE)
Pseudoxanthoma elasticum (PXE) is a rare genetic disorder characterized by ectopic calcifications in the skin, retina and arterial walls. Angers University Hospital is the national rare disease reference center (CRMR) for PXE.
- Trial name
- REMOTE-PXE (NCT06636344)
- Testing
- Pseudoxanthoma Elasticum
- Where
- France
- Volunteers
- 650 people
- Sponsor
- University Hospital, Angers
Nutritional Deficiency in Pregnancy
Enhancing the Effectiveness of Home-delivery Based Produce Prescription Program Implementation Strategies
Harris Health System is currently participating, along with two other partners, GoldiFresh Inc., and Brighter Bites, in a cross-sector collaborative home delivery-based Produce Prescription Program (PPRx) pilot initiative that…
- Trial name
- NCT06114199
- Testing
- Produce Prescription Program (PPRx) Standard, Smartphone App
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
ICU Patients, Surgical
Implementation of Clinical Nutrition Practice Guidelines in Surgical ICUs
The goal of this interventional clinical trial is to evaluate whether the implementation of an evidence-based, context-adapted clinical nutrition practice guideline can improve clinical nutrition management in surgical intensive…
- Conditions
- ICU Patients, Surgical, Nutrition Intervention, Enteral Nutrition
- Trial name
- NCT07337798
- Testing
- Guideline Implementation
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Cardiac Diseases, Sickle Cell Disease
Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System
Cognizant of the prevalence of complicated non communicable diseases (NCD) and the attendant capacity problems faced by the health workers in primary care settings, we propose to adapt and pilot the Package of Essential…
- Conditions
- Cardiac Diseases, Sickle Cell Disease, Hypertension, Diabetes Mellitus
- Trial name
- PEN Plus (NCT07753681)
- Testing
- Supportive treatment
- Where
- Zambia
- Volunteers
- 2,084 people
- Sponsor
- Centre for Infectious Disease Research in Zambia
Acute Kidney Injury, Renal Replacement Therapy
FST Analysis Supporting Timely Therapy and Risk Assessment Via Clinical Decision Support for Kids
The goal of this study is to learn whether adding a clinical decision support tool to the electronic medical record helps clinicians use the furosemide stress test in critically ill children at high risk for severe acute kidney…
- Conditions
- Acute Kidney Injury, Renal Replacement Therapy, Pediatric Intensive Care Unit
- Trial name
- FAST TRACK (NCT07718464)
- Testing
- Furosemide Stress Test Clinical Decision Support Tool
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Opioid Use Disorder
Coordinating Outpatient bupreNorphiNe for Emergency Care and Continuing Treatment
The main purpose of this stepped wedge trial will be to test the impact of a bundle of implementation strategies designed to improve ED-outpatient care coordination on long-term buprenorphine retention among adult patients who…
- Trial name
- CONNECT (NCT07024498)
- Testing
- care coordination implementation strategies
- Where
- 4 sites in United States
- Volunteers
- 3,492 people
- Sponsor
- University of California, Davis
Children Unable to Walk Independently
Upright Participation for Learners: Implementation of Flexible Use of roboT-assisted Walking in Schools - PILOT
Robot-assisted walking offers children who are unable to walk new avenues for participation in their communities in addition to health benefits. Disappointingly, most children cannot access this impactful technology.
- Trial name
- UPLIFTS Pilot (NCT07726706)
- Testing
- Robotic walking
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Calgary
Colorectal Cancer (CRC) Screening
A Novel Multi-functional Artificial Intelligence System on Treatment Efficacy and Implementation in Colonoscopy
To overcome non-neoplastic polyp (NNP) resections, computer-aided diagnosis (CADx) systems have been developed. In a meta-analysis, the performance of CADx systems was superior to endoscopists.
- Trial name
- mAInstream (NCT07844252)
- Testing
- CADe/CADx
- Volunteers
- 2,818 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Occupational Health, Stress
Implementation of the ASCEND Training for Supervisors in Dutch Small and Medium-sized Enterprises (SMEs)
This cluster randomized controlled trial (cRCT) aims to evaluate the effectiveness of the Dutch adaptation of an in-person group intervention for workplace supervisors - Advancing Supervisors' Capacity for Mental Health at Work…
- Conditions
- Occupational Health, Stress, Burnout, Mental Health Conditions
- Trial name
- NCT06989398
- Testing
- Advancing Supervisors' Capacity for Mental Health at Work (ASCEND)
- Where
- Netherlands
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Hernia, Inguinal, Hernia, Femoral
Recover@Home Postoperative Follow-up Study
This proposal describes a human subjects research study evaluating mHealth Ambulatory Surgery with Follow-up Nurse (Recovery@Home), as an alternative postoperative care pathway for selected low-acuity surgical procedures in…
- Conditions
- Hernia, Inguinal, Hernia, Femoral, Hernia, Umbilical, Hernia, Ventral
- Trial name
- NCT07714343
- Testing
- Recovery@home
- Where
- 4 sites in Uganda
- Volunteers
- 194 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hiv, Transmission Vertical
Enhanced Mentor Mother Strategy for Pregnant and Postpartum Women Living With HIV
Mentor Mothers (MMs) are peer supporters who help pregnant and postpartum women living with HIV (WLHIV) as they receive prevention of mother-to-child transmission of HIV (PMTCT) services in resource-limited settings like Kenya.
- Conditions
- Hiv, Transmission Vertical, Viremia, Adherence, Treatment
- Trial name
- PIE-eMMs (NCT06999928)
- Testing
- Enhanced Mentor Mother Strategy
- Where
- Kenya
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pediatric Obesity, Rural Health
iAmHealthy Clinical Practice Guideline (CPG)
The current study is a multilevel factorial design RCT with interventions at the clinic (Healthy Clinic intervention period vs. Control period) and individual patient levels (iAmHealthy vs. Newsletter).
- Conditions
- Pediatric Obesity, Rural Health, Clinical Practice Guideline
- Trial name
- NCT06888011
- Testing
- Participants: iAmHealthy, Participants: Newsletter
- Where
- 4 sites in United States
- Volunteers
- 1,024 people
- Sponsor
- University of Kansas Medical Center
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