Clinical trials: Implementation, open to volunteers
Lung Cancer, Cancer of the Lung
Implementation and Effectiveness of the BJC-Pink and Pearl Project on Lung Cancer Screening
The investigators proposal is ripe for executing as the investigators seek to leverage this "natural experiment" initiated by the BJC health system to evaluate the effectiveness of the Pink \& Pearl Campaign as an implementation…
- Trial name
- NCT06898333
- Where
- United States
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Inflammatory Bowel Disease
Testing the Impact of Measurement-Based Care on Quality of Life and Disease Management Among Veterans With Inflammatory Bowel Disease
This research study is addressing issues related to Inflammatory bowel disease (IBD), which is a chronic autoimmune disorder that affects over 60,000 Veterans.
- Trial name
- MBC-IBD (NCT07210580)
- Testing
- MBC-IBD Intervention, Enhanced Treatment as Usual (E-TAU)
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- VA Office of Research and Development
Eating Disorders in Adolescence, Transition of Care
Feasibility of the TransitionED Framework for Youth and Young Adults With Eating Disorders
Moving from pediatric (children's) health care to adult health care can be challenging for youth and young adults with eating disorders.
- Trial name
- TransitionED 3 (NCT07518641)
- Testing
- TransitionED Healthcare Transition Framework
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- McMaster University
Hip Arthroplasty, Total, Knee Arthroplasty, Total
Perceptions of De-implementing Routine Follow-ups After Hip and Knee Arthroplasty
After undergoing total hip or total knee arthroplasty, current guidelines recommend routine follow-up with an X-ray within 3 months and again at 1 year.
- Trial name
- HAKA-QUALI (NCT07041528)
- Where
- Netherlands
- Volunteers
- 90 people
- Sponsor
- Tergooi Medical Center
Breast Carcinoma, Malignant Digestive System Neoplasm
Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital
This study examines how the American College of Surgeons Geriatric Surgery Verification Program, also called the ACS GSV Program, is implemented at the James Cancer Hospital.
- Conditions
- Breast Carcinoma, Malignant Digestive System Neoplasm, Malignant Female Reproductive System Neoplasm, Malignant Genitourinary System Neoplasm
- Trial name
- NCT07606287
- Testing
- Serious Illness Conversation Program training, ACS Geriatric Surgery Verification Program Implementation
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Heart Failure, Chronic Heart Failure (CHF)
SUPPORT-HEART-PK: Effectiveness, Implementation, and Cost-Effectiveness of a Theory-Based, RE-AIM-Informed Digital Self-Management Intervention for Heart Failure in Pakistan-A Hybrid Type 1 Effectiveness-Implementation Randomized Controlled Trial
Medication non-adherence leads to recurrent admissions, worsening symptoms, poor quality of life, and increased healthcare costs in an already overburdened health system.
- Trial name
- NCT07580508
- Testing
- RE-AIM-informed autonomy-competence intervention
- Where
- Pakistan
- Volunteers
- 870 people
- Sponsor
- Universiti Putra Malaysia
Implementation Science, Chronic Disease Self-management
Adapting and Implementing a Chronic Disease Self-Management Program for Primary Care Patients With Opioid Use Disorder and Serious Mental Illness
The purpose of this study is to evaluate a self-management education program designed to help people with opioid use disorder (OUD), serious mental illness (SMI), and other chronic health conditions better manage their health.
- Conditions
- Implementation Science, Chronic Disease Self-management, Mental Illness, Addiction
- Trial name
- NCT07865078
- Testing
- The Chronic Disease Self-Management Program (CDSMP), Treatment as Usual plus self-management information
- Volunteers
- 40 people
- Sponsor
- University of Utah
Mental Health, Parenting Stress
SBIR/ STTR Family Check-up Online
The Family Check-Up Online, a digital health intervention, was designed to improve child mental health through family-centered intervention.
- Conditions
- Mental Health, Parenting Stress, Academic Achievement, Parenting Skills
- Trial name
- NCT06876246
- Testing
- Family Check-Up Online, FCU Online with Telehealth Coaching
- Where
- United States
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Colorectal Surgery
Colorectal Surgery, a New Robotic Platform (Hugo Ras)
A novel robotic platform -Hugo Robotic Assisted Surgery (RAS)- has been introduced with several innovations that may prove advantageous for surgeons such as an open console and four interchangeable modular arms.
- Trial name
- NCT06512480
- Testing
- colonic resection
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
HIV, PrEP
Pharmacy-based Provision of Pre-exposure Prophylaxis (PrEP) for Adolescent Girls and Young Women in Tanzania
Implementation study comparing standard pre-exposure prophylaxis (PrEP) services to four models of pharmacy-based PrEP access for young women aged 18-24 (YW) in Tanzania.
- Trial name
- MWOTAJI (NCT07687888)
- Testing
- Pharmacy-based PrEP services, Distribution of HIV self-test kits
- Where
- Tanzania
- Volunteers
- 2,818 people, healthy volunteers welcome
- Sponsor
- Mzumbe University - Centre of Excellence in Health Monitoring and Evaluation
Pulmonary Embolism
Nudging Provider Adoption of Clinical Decision Support: Implementation of an EHR-Agnostic Pulmonary Embolism Risk Prediction Tool
The purpose of this study is to examine the impact of the nudge implementation strategy (CDS tool + Nudge) on adoption of guideline-concordant CT ordering for pulmonary embolism (PE) in 10 EDs.
- Trial name
- NCT07249385
- Testing
- Clinical Decision Support (CDS) tool with Nudges
- Where
- 3 sites in United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Advanced Heart Failure, Acquired Heart Disease
TORCH-LATAM-004: Regional Advanced-Therapy Pathways for Adults With Acquired or Structural Heart Disease
TORCH-LATAM-004 is a pragmatic stepped-wedge cluster randomized trial evaluating a regional pathway for adults with advanced heart failure secondary to acquired or structural heart disease who may require heart or combined…
- Conditions
- Advanced Heart Failure, Acquired Heart Disease, Structural Heart Disease, Heart Transplantation
- Trial name
- TORCH-004 (NCT07826078)
- Testing
- TORCH Adult Advanced Therapies Pathway (TORCH-AATP)
- Volunteers
- 360 people
- Sponsor
- CardioVision International Tech, S.A.S. de C.V.
Health Behavior, Adolescence
THRIVE-Belize: A School-Based Life-Skills Program to Support Teen Health in Toledo District, Belize (Feasibility)
THRIVE-Belize is a school-based program being developed to support the health and well-being of adolescents in the Toledo District of southern Belize.
- Conditions
- Health Behavior, Adolescence, Feasibility Studies
- Trial name
- THRIVE-Belize (NCT07687199)
- Where
- Belize
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Coronary Artery Bypass Graft (CABG)
Saudi CABG Audit and Registry
The Saudi CABG Audit and Registry (SCAR) is a prospective, multicenter national clinical quality registry designed to systematically collect perioperative and long-term outcome data for all patients undergoing coronary artery…
- Trial name
- SCAR (NCT07316777)
- Testing
- Prospective Clinical Data Collection
- Volunteers
- 3,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Aortic Dissection
Research on the Development and Implementation of an Exercise Rehabilitation Program for Aortic Dissection Patients After Percutaneous Intervention Based on the Behavior Change Wheel Theory
Study Title ： Effectiveness of a BCW Theory-Based Exercise Rehabilitation Program in Post-Endovascular Aortic Dissection Patients: A Randomized Controlled Trial Primary Objective ： To determine whether an exercise rehabilitation…
- Trial name
- NCT07117500
- Testing
- Routine, BCW
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shuzhen Wang
Breast Cancer, Ovarian Cancer
Navigation Intervention for Adolescent and Young Adult Cancer Survivors
The investigators propose to: 1) Adapt an evidence-based cancer-focused patient navigation (PN) program for the Adolescent and Young Adult (AYA) cancer survivor population; and 2) Plan and conduct an effectiveness-implementation…
- Conditions
- Breast Cancer, Ovarian Cancer, Cervical Cancer, Testicular Cancer
- Trial name
- NCT07406087
- Testing
- Adapted patient navigation program targeting adolescent and young adult cancer survivors
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Kaiser Permanente
Posttraumatic Stress Disorder (PTSD), Substance Use Disorders (SUD)
Project COMET: Massed Prolonged Exposure for PTSD and SUD
The goal of this clinical trial is to learn if Massed Prolonged Exposure Therapy (M-PE) can improve PTSD symptoms and reduce substance use in adults receiving intensive outpatient (IOP) treatment for substance use disorder (SUD).
- Conditions
- Posttraumatic Stress Disorder (PTSD), Substance Use Disorders (SUD), Comorbidity, Trauma and Stressor Related Disorders
- Trial name
- PROJECT COMET (NCT06968832)
- Testing
- Massed Prolonged Exposure Therapy (M-PE), Standard outpatient SUD care
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Rutgers, The State University of New Jersey
HIV Prevention
Pre-exposure Prophylaxis (PrEP) Adherence for Black MSM
The goal of this clinical trial is to learn if two interventions-C4 and C4+3MV-can improve PrEP adherence (taking medication to prevent HIV) among Black men who have sex with men (MSM).
- Trial name
- C4+3MV (NCT06661343)
- Testing
- C4 Program, C4 + 3MV Program
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yale University
Type 2 Diabetes, Overweight and Obese Adults
Plant-Based Online Weight Loss Through Education and Resources Program and Study
This is an interventional study that will evaluate the feasibility, implementation, and efficacy of an online, 12-week, plant-based, nutrition education program in a community setting.
- Trial name
- POWER (NCT07095543)
- Testing
- Low-fat, vegan diet
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Physicians Committee for Responsible Medicine
Psychological Distress, Stress Psychological
A Community-based, Peer-led Counseling Service: A Hybrid Type 3 Effectiveness-implementation Study
The goal of this observational study is to learn how a community-based peer counselling service works in everyday practice and whether it helps people who are going through a psychologically difficult time.
- Conditions
- Psychological Distress, Stress Psychological, Mental Health, Recovery
- Trial name
- NCT07879443
- Volunteers
- 65 people
- Sponsor
- St.Gallen University of Applied Sciences
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