Clinical trials: Implementation, open to volunteers
Depression, HIV
Implementing Depression and Adherence Treatment
The goal of this clinical trial is to compare a core set and enhanced set of implementation strategies in increasing the reach of evidence-based treatments to patients with HIV and depression.
- Conditions
- Depression, HIV, Adherence, Treatment, AIDS
- Trial name
- NCT07032363
- Testing
- Core Implementation Strategies, Enhanced Implementation Strategies
- Where
- South Africa
- Volunteers
- 10 people
- Sponsor
- University of Miami
Depression
Implementation of Problem-Solving Treatment in Community Health Centers (PST-Aid)
Although evidence-based clinical interventions (CI) are a preferred treatment option for patients with depression, CIs are rarely available in community primary care settings.
- Trial name
- NCT06494384
- Testing
- Problem Solving Treatment as usual (PST as usual), Problem Solving Treatment Aid (PST-Aid)
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- University of Washington
Point of Care STI Testing
Point of Care STI Testing
The proposed research hypothesizes that point-of-care testing (POCT) for sexually transmitted infections (STIs) gonorrhea and chlamydia will be a feasible, acceptable, and appropriate implementation strategy for improving HIV…
- Trial name
- NCT06844045
- Testing
- Gonorrhea/chlamydia Point-of-Care Testing
- Where
- United States
- Volunteers
- 6,460 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cancer, Cancer Diagnosis
Avera Cancer Sequencing and Analytics Protocol (ASAP)
The purpose of this study is to characterize the breadth of molecular features present in participants receiving care within a large, integrated, community-based healthcare system.
- Conditions
- Cancer, Cancer Diagnosis, Early Detection of Cancer, Breast Cancer
- Trial name
- ASAP (NCT05142033)
- Where
- 6 sites in United States
- Volunteers
- 25,000 people
- Sponsor
- Avera McKennan Hospital & University Health Center
Sepsis, Sepsis Mrsa
Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis
The goal of this quasi-experimental interventional study is to determine the effectiveness of a multifaceted stewardship intervention in reducing overall vancomycin use in five tertiary care Pediatric Intensive Care Units (PICU).
- Conditions
- Sepsis, Sepsis Mrsa, Sepsis Bacteremia, Antimicrobial - Induced Nephropathy
- Trial name
- REVAMP (NCT05975671)
- Testing
- Multifaceted de-implementation strategy to reduce vancomycin overuse
- Where
- 4 sites in United States
- Volunteers
- 52,500 people
- Sponsor
- Children's Hospital of Philadelphia
Diabetic Foot Ulcer, Type 2 Diabetes Mellitus With Complication
Implementation of a Preventive Diabetic Foot Care Program for Patients at Risk of Diabetic Foot
This study aims to evaluate the effect of a preventive diabetic foot care program on the knowledge, behavior, self-management, and glycemic control levels of type 2 diabetic patients at risk of diabetic foot.
- Trial name
- NCT06770829
- Testing
- DiaFOOTCare Program, Ministry of Health and Education
- Volunteers
- 78 people
- Sponsor
- Akdeniz University
Autism Spectrum Disorders
Water Competency Intervention in Autism
AquOTic is an evidence-based, occupational therapy-led intervention designed to enhance water competency and swim safety skills in children on the autism spectrum.
- Trial name
- NCT07076264
- Testing
- AquOTic
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Ohio State University
Acute Dyspnea
Implementation of Mobile Intensive Care Unit Ultrasound Based Management for Acute Dyspnea
This multicentre, cluster-randomised, stepped-wedge clinical trial aims to assess whether an intervention designed to implement an ultrasound-guided pre-hospital care pathway for the management of acute dyspnea would improve the…
- Trial name
- IMICU2-Dyspnea (NCT07852364)
- Testing
- Ultrasound pre-hospital care
- Where
- 11 sites in France
- Volunteers
- 800 people
- Sponsor
- Central Hospital, Nancy, France
Wrist Osteoarthritis, Wrist Fracture
Barriers and Facilitators in Radiographic Devices and Imaging
This study aims to understand factors that may influence the implementation of a wrist-specific radiographic positioning device in healthcare settings across the United States and Canada.
- Conditions
- Wrist Osteoarthritis, Wrist Fracture, Wrist Injury
- Trial name
- NCT07766239
- Testing
- Survey using a questionnaire.
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Western University
Total Knee Arthroplasty, Functional Recovery
Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty
Patients experience dramatic quadriceps strength loss after total knee replacement, which contributes to persistent weakness and reduced long-term function after surgery.
- Conditions
- Total Knee Arthroplasty, Functional Recovery, Aging, Physical Therapy
- Trial name
- NCT06953375
- Testing
- NMES, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 3,250 people
- Sponsor
- University of Colorado, Denver
Current Status of Analgesia and Sedation Cognition and Implementation
Emergency Room Analgesia and Sedation Survey-2
Part 1: Assessment of Healthcare Providers' Knowledge on Analgesia and Sedation in Emergency Resuscitation Rooms Across China This study aims to evaluate the understanding of healthcare providers in emergency resuscitation rooms…
- Trial name
- EASY-2 (NCT07152457)
- Testing
- No intervention
- Volunteers
- 13,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Back Pain
Self-management of Low Back Pain in Horticulture Workers
The primary purpose of this hybrid Type II comparative effectiveness and implementation study is to compare two self-management strategies in nursery and landscape workers.
- Trial name
- NCT06153199
- Testing
- Self-management videos, Check lists for ergonomic options, Text reminders
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University of Florida
Malaria
Integrating the Guardian Spatial Emanator Within AVENIR II
This study will evaluate the implementation of integrating Guardian spatial emanators into the existing AVENIR II azithromycin mass drug administration program in Niger.
- Trial name
- GUARD-AV (NCT07712263)
- Testing
- Spatial Emanator
- Where
- Niger
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Spine Deformity, Idiopathic Scoliosis
Implementation of Momentum SpineTM: a New 3D Imaging Software for Idiopathic Scoliosis
Brief Summary The goal of this clinical trial is to evaluate the implementation of Momentum Spine™, a new 3D imaging software designed to improve the monitoring and management of idiopathic scoliosis in children aged 8-14 years.
- Trial name
- NCT06777992
- Testing
- Home topographic scans
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Physical Activity
Evaluating an Implementation Strategy to Improve Physical Activity and Reduce Cardiovascular Risk Factors in Children
The purpose of this study is to evaluate the impact of enhanced Movement for Academic Growth In Classrooms (MAGIC) for improving implementation and effectiveness of physically active breaks, lessons, and motor labs
- Trial name
- NCT07541118
- Testing
- MAGIC, Control
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
HIV Prevention, HIV Pre-exposure Prophylaxis
PEP/PrEP Via Pharmacist-Prescribing Implementation (PEPPI)
The goal of this clinical trial is to learn if use of the PEPPI software can improve pharmacist-provided HIV prevention (PEP/PrEP) services. The main questions it aims to answer are: 1.
- Conditions
- HIV Prevention, HIV Pre-exposure Prophylaxis, Access and Linkage to Healthcare, Technology Use
- Trial name
- PEPPI (NCT07683117)
- Testing
- PEPPI Pharmacies
- Where
- United States
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- EMPOWERX INC
Pain, Substance Use
M2VA Pain Care Pathway
The goal of this 2-cohort, cluster randomized, type 2 hybrid trial is to test the effectiveness, cost-effectiveness and patient-level effects of an implementation facilitation strategy in helping M2VA case managers adopt a…
- Conditions
- Pain, Substance Use, Opioid Misuse, Quality of Life
- Trial name
- M2VAPCP (NCT06526143)
- Testing
- M2VA Pain Care Pathway (M2VAPCP), Implementation Facilitation
- Where
- United States
- Volunteers
- 1,800 people
- Sponsor
- Yale University
Cancer
Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)
The purpose of the study is to understand patient interest in telehealth and digital tools for pre-test genetic education and/or disclosure of genetic test results.
- Trial name
- eREACH3 (NCT07471958)
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Cancer, Abdominal Cancer Surgery
Developing Pilot Postoperative Guidelines for Improved Functional Outcomes After High-Risk Cancer Surgery
The objective of this study is to develop and evaluate the implementation of novel timeline-specific National Comprehensive Cancer Network (NCCN)-style clinical guidelines designed to improve functional outcomes after high-risk…
- Conditions
- Cancer, Abdominal Cancer Surgery, Surgery, Recovery Outcomes
- Trial name
- NCT07720089
- Testing
- Algorithmic Guideline for Functional Recovery following Cancer Surgery
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of Alabama at Birmingham
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8
A Navigation Program to Improve Survivorship Support Service Participation Among Non-metastatic Breast Cancer Survivors
This clinical trial studies whether a navigation program improves survivorship support service participation among survivors of breast cancer that has not spread from where it first started (primary site) to other places in the…
- Conditions
- Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
- Trial name
- NCT07699991
- Testing
- Best Practice, Patient Navigation, Referral
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
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