Clinical trials: Implementation
Prostate Cancer, Gynecologic Cancers
Quality and Safety of Real-Time Brachytherapy Treatments: Clinical Implementation of a Multipoint Scintillation Detector for Treatment Monitoring
This project addresses a key safety gap in High-Dose-Rate (HDR) brachytherapy, where very high, localized radiation doses mean that small geometric deviations in catheter placement or radioactive source positioning can cause…
- Trial name
- (CurieInVivo) (NCT07580651)
- Testing
- Brachytherapy treatment monitoring using a plastic scintillation detector
- Volunteers
- 25 people
- Sponsor
- CISSS de Chaudière-Appalaches
Social Determinants of Health, Primary Care
DEDICATE: aDvancing carE Management aDoption In Community heAlTh cEnters
DEDICATE will refine and test the effectiveness of evidence-based implementation support strategies designed to support care management teams' sustained use of electronic health record (EHR)-based functionalities to address unmet…
- Conditions
- Social Determinants of Health, Primary Care, Diabetes Mellitus, Type 2, Hypertension
- Trial name
- DEDICATE (NCT06489002)
- Testing
- Implementation Support
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- OCHIN, Inc.
Eating Disorder
Implementation Support for Prevention Program Delivery by College Peer Educators
This project will evaluate 3 approaches of implementation support for university peer leaders who will deliver a prevention program with a particularly strong evidence-base compared to changes observed in outcomes in response to…
- Trial name
- PI (NCT03409809)
- Testing
- Training, Training and Technical Assistance, Training, Tech. Assistance, Quality Assurance/Improvement
- Where
- 4 sites in United States
- Volunteers
- 2,261 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Death, Communication, Multidisciplinary
A Multicenter Implementation Study of the 3 Wishes Project
The 3 Wishes Project (3WP) was created to promote the connections between patients, family members, and clinicians that are foundational to empathic end-of-life care.
- Conditions
- Death, Communication, Multidisciplinary, Empathy, Compassion
- Trial name
- 3WP (NCT04147169)
- Testing
- Focused end-of-life conversations to promote connections among patients, family members and clinicians.
- Where
- Canada
- Volunteers
- 730 people
- Sponsor
- McMaster University
Myocardial Infarction
Finding LCX AMI With Posterior ECG LeadS
Along with symptoms of chest pain, the presence of ST segment elevations on ECG is the criterion usually used in practice to identify patients with acute coronary artery occlusion and is essential for the direct and acute…
- Trial name
- FLAWLESs (NCT02788799)
- Testing
- Standard 12-Lead ECG, Posterior ECG Leads
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Glaucoma, Suspect, Diabetic Retinopathy
Eye Health Intervention Study in Upper Manhattan
Individuals living in Upper Manhattan have limited access to eye care, high vision impairment rates, and poor ocular health outcomes.
- Conditions
- Glaucoma, Suspect, Diabetic Retinopathy, Cataract, Refractive Errors
- Trial name
- EYES-UM (NCT06112431)
- Testing
- Intervention, Usual Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Colorectal Surgery
Colorectal Surgery, a New Robotic Platform (Hugo Ras)
A novel robotic platform -Hugo Robotic Assisted Surgery (RAS)- has been introduced with several innovations that may prove advantageous for surgeons such as an open console and four interchangeable modular arms.
- Trial name
- NCT06512480
- Testing
- colonic resection
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Autonomic Dysfunction, Stress, Psychological
The SongDanceT1 Study: Stress, Ongoing Self- Monitoring and Diabetes, Nerve Stimulation and Cognitive Empowerment.
In an implementation study, designed as a RCT in people with type 1 diabetes(T1D) and an elevated Pressure pain sensitivity of the chest bone(PPS) as indicative of dysfunction of the autonomic nervous system (ANSD), to describe…
- Trial name
- SongDanceT1 (NCT06087679)
- Testing
- PPS guided selfcare based intervention program
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Steno Diabetes Center Copenhagen
Diabetes, Cystic Fibrosis
Training in Shared Decision-making of Cystic Fibrosis Centers Competences in the Treatment of CF Related Diabetes in Adult Patients
Diabetes affects half of cystic fibrosis patients aged 30 years and older. It develops asymptomatically for a long time. Also, two options are possible: start insulin treatment now with the additional constraints associated with…
- Trial name
- FORAIDMUCO (NCT04891159)
- Testing
- Shared decision making
- Where
- 4 sites in France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Low Back Pain
Telerehabilitation-based Exercises vs Standard Home-based Exercise in Low Back Pain
The objective of the study is to compare the effect of a telerehabilitation-based exercise program, versus a home therapeutic exercise program scheduled through a dossier and an exercise diary, with respect to disability…
- Trial name
- NCT06446596
- Testing
- Exercise supported by the digital physiotherapy and telerehabilitation software TRAK, Standard home-based exercise
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Valencia
Sexually Transmitted Diseases, Disease Transmission, Infectious
Eban II: Intervention for HIV Sero-Discordant Couples
This study focuses on the implementation of an evidence-based HIV risk reduction intervention for HIV-serodiscordant, heterosexual African American couples ("Eban II") in two geographic areas (Northern and Southern California …
- Conditions
- Sexually Transmitted Diseases, Disease Transmission, Infectious, Safe Sex, HIV
- Trial name
- NCT01829282
- Testing
- Risk Reduction
- Where
- 8 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Psychiatric Hospitalization
Implementation of Caring Contacts
This quality improvement (QI) project will adapt and improve an evidence-based suicide-prevention initiative for Sunnybrook patients at high risk of suicide following psychiatric inpatient discharge, targeting one of Sunnybrook's…
- Trial name
- NCT05294549
- Testing
- Caring Contact
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Sunnybrook Health Sciences Centre
Uterine Fibroid
Implementation of Uterine Fibroid Option Grid Patient Decision Aids Across Five Organizational Settings
UPFRONT is a study that aims to use two implementation frameworks - the Consolidated Framework for Implementation Research and the Normalization Process Theory - to guide the implementation of a uterine fibroid patient decision…
- Trial name
- UPFRONT (NCT03985449)
- Testing
- Uterine Fibroid Option Grid encounter patient decision aid (text only), Uterine Fibroid Option Grid encounter patient decision aid (text + Pictures), Uterine Fibroid Option Grid encounter patient decision aid (online)
- Where
- United States
- Volunteers
- 748 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Domestic Violence, Child Development
Musical Group Intervention for Children in Shelters
The aim of the study is to augment knowledge on interventions for children who live, or have lived, in shelters after exposure to domestic violence.
- Conditions
- Domestic Violence, Child Development, Psychological Distress, Music Therapy
- Trial name
- NCT05755178
- Testing
- Music, feelings and relationships - music group for children at shelters
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Kronoberg County Council
Vitiligo
Vitiligo Extent Score (VES) Score in Comparison to Vitiligo Area and Severity Index (VASI) Score
All patients with vitiligo attending dermatology outpatient clinic at Kasr Alainy Teaching Hospital will be enrolled in this study to compare VES and VASI scores and evaluate them as assessment methods
- Trial name
- NCT03411135
- Testing
- VES and VASI scores as assessment methods for vitiligo
- Volunteers
- 101 people
- Sponsor
- Cairo University
Stage II Breast Cancer, Stage III Breast Cancer
Ask Questions (ASQ):Implementation of a Communication Intervention
This clinical trial implements a communication intervention to improve patient-oncologist communication in the outpatient medical oncology setting.
- Conditions
- Stage II Breast Cancer, Stage III Breast Cancer, Stage IV Breast Cancer, Stage II Colorectal Cancer
- Trial name
- NCT05025748
- Testing
- Behavioral Intervention
- Where
- 8 sites in United States
- Volunteers
- 81 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Temporomandibular Dysfunction (TMD), Orofacial Pain
Electrostimulation Therapies With Implementation of Multifractal Electromyographic Analysis
The objective is to compare the neuromuscular electrical activity and muscle fatigue of the masseter muscles in three groups of patients with different treatments for TMD (GA = Transcutaneous electrostimulation and splint, GB =…
- Trial name
- NCT04704778
- Testing
- Transcutaneus electrostimulation therapies, Percutaneus electrostimulation therapies, Oclusal splint
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Cancer
The Research of French PaRole OncO : A Peer Supported Program for Cancer Patients
Peer support is a valuable mode of accompaniment between individuals who are facing or have faced similar challenging life experiences.
- Trial name
- PROOF (NCT06817655)
- Testing
- PaRole OncO France : Individual peer support
- Where
- 2 sites in France
- Volunteers
- 720 people
- Sponsor
- Hospices Civils de Lyon
Pressure Injury
Machine Learning-Based Pressure Injury Staging and Nursing Care in Intensive Care
This study aims to develop a mobile nursing care system that uses machine learning to support pressure injury staging and to evaluate its effect on pressure injury healing in an intensive care unit.
- Trial name
- NCT07853534
- Testing
- Mobile Application for Pressure Injury Staging and Nursing Care Guidance, Standard Clinical Care
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ertugrul Sari
Intensive Care
Impact of the Implementation of a Clinical Pharmacy Bundle on Intensive Care Unit Patient Outcomes and Cost Expenditures
The aim of this before-after study was to assess the impact of a clinical pharmacy bundle of care activities on patient outcomes (length of hospital stay as a primary endpoint) and cost expenditure in two French ICUs.
- Trial name
- NCT02924844
- Where
- France
- Volunteers
- 2,787 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes